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https://www.readbyqxmd.com/read/29046039/topical-review-transitional-services-for-teens-and-young-adults-with-attention-deficit-hyperactivity-disorder-a-process-map-and-proposed-model-to-overcoming-barriers-to-care
#1
Jason M Fogler, David Burke, James Lynch, William J Barbaresi, Eugenia Chan
Objective: To provide a topical review of the personal vulnerabilities and systemic barriers facing transitional age young adults with attention-deficit hyperactivity disorder (ADHD), followed by a proposed model for overcoming those barriers. Methods: Drawing from a growing, but limited, literature on the topic, we outline a process map for identifying and troubleshooting barriers to care in this at-risk population. Results: Young adults with ADHD frequently lack the organizational skills, time management, prioritization, and persistence to manage their health care at an expected level of adult independence...
November 1, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29045273/oneflorida-clinical-research-consortium-linking-a-clinical-and-translational-science-institute-with-a-community-based-distributive-medical-education-model
#2
Elizabeth Shenkman, Myra Hurt, William Hogan, Olveen Carrasquillo, Steven Smith, Andrew Brickman, David Nelson
PROBLEM: Developing a national pragmatic clinical trial infrastructure is central to understanding the effectiveness of interventions applied under usual conditions and where people receive health care. To address this challenge, three Florida universities- the University of Florida Clinical and Translational Science Institute, Florida State University (with its community-based distributive medical education model), and the University of Miami-created (2010-2013) a statewide consortium, the OneFlorida Clinical Research Consortium, to support the conduct of pragmatic clinical trials and provide mentored research experiences for medical and graduate students in real-world practice settings...
October 17, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29044796/social-traits-social-networks-and-evolutionary-biology
#3
David N Fisher, Andrew G McAdam
The social environment is both an important agent of selection for most organisms, and an emergent property of their interactions. As an aggregation of interactions among members of a population, the social environment is a product of many sets of relationships, and so can be represented as a network or matrix. Social network analysis in animals has focused on why these networks possess the structure they do, and whether individuals' network traits, representing some aspect of their social phenotype, relate to their fitness...
October 17, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/29044467/the-influence-of-text-cohesion-and-picture-detail-on-young-readers-knowledge-of-science-topics
#4
Juliette C Désiron, Erica de Vries, Anna N Bartel, Nalini Varahamurti
BACKGROUND AND AIM: The effects of text cohesion and added pictures on acquired knowledge have been heavily studied each in isolation. Furthermore, studies on the effects of specific characteristics of pictures, whether facilitating or hindering, are scarce. Schnotz's ITCP Model (2014) allows to formulate hypotheses regarding the combined effect of text cohesion and presence and level of detail of a picture. This study investigates these hypotheses in the case of children reading scientific texts...
October 16, 2017: British Journal of Educational Psychology
https://www.readbyqxmd.com/read/29043860/development-and-in-vitro-in-vivo-evaluation-of-hpmc-chitosan-gel-containing-simvastatin-loaded-self-assembled-nanomicelles-as-a-potent-wound-healing-agent
#5
Jaleh Varshosaz, Somayeh Taymouri, Mohsen Minaiyan, Fatemeh Rastegarnasab, Azar Baradaran
The aim of this study was to develop hydroxypropyl methyl cellulose (HPMC)/chitosan gel containing polymeric micelles loaded with simvastatin (Sim) and evaluates its wound healing properties in rats. An irregular full factorial design was employed to evaluate the effects of various formulation variables including polymer/drug ratio, hydration temperature, hydration time and organic solvent type on the physicochemical characteristics of pluronic F127-cholesterol nanomicelles prepared using the film hydration method...
October 18, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/29043773/coherence-spectroscopy-in-the-condensed-phase-insights-into-molecular-structure-environment-and-interactions
#6
Jacob C Dean, Gregory D Scholes
The role of coherences, or coherently excited superposition states, in complex condensed-phase systems has been the topic of intense interest and debate for a number of years. In many cases, coherences have been utilized as spectators of ultrafast dynamics or for identifying couplings between electronic states. In rare cases, they have been found to drive excited state dynamics directly. Interestingly though, the utilization of coherences as a tool for high-detail vibronic spectroscopy has largely been overlooked until recently, despite their encoding of key information regarding molecular structure, electronically sensitive vibrational modes, and intermolecular interactions...
October 18, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29043523/analysis-of-potential-factors-affecting-allografts-contamination-at-retrieval
#7
A Paolin, C Romualdi, L Romagnoli, D Trojan
The microbiological contamination of retrieved tissues has become a very important topic and it is a critical aspect in the safety of allografts, especially from multi-tissue donors whose tissues are frequently contaminated as a consequence of retrieval. We analysed a total of 10,107 tissues, 8178 musculoskeletal and 1929 cardiovascular tissues, retrieved from 978 multi-tissue donors. Of these, 159 heart-beating donors (HBD) were also organ donors, while the remaining 819 non-heart-beating donors (NHBD) were tissue donors only...
October 17, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/29043322/chirality-in-adsorption-on-solid-surfaces
#8
REVIEW
Francisco Zaera
In the present review we survey the main advances made in recent years on the understanding of chemical chirality at solid surfaces. Chirality is an important topic, made particularly relevant by the homochiral nature of the biochemistry of life on Earth, and many chiral chemical reactions involve solid surfaces. Here we start our discussion with a description of surface chirality and of the different ways that chirality can be bestowed on solid surfaces. We then expand on the studies carried out to date to understand the adsorption of chiral compounds at a molecular level...
October 18, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/29043082/effect-of-sex-and-age-on-traumatic-brain-injury-a-geographical-comparative-study
#9
Raaj Kishore Biswas, Enamul Kabir, Rachel King
BACKGROUND: Traumatic brain injury (TBI) is a much researched topic in medical health, which requires additional studies to understand various effects of demographic and geographic factors that can assist in developing the most effective treatments. Thousands of people of different ages are suffering from lifelong disabilities, either mild or severe, from TBI and the number is increasing. This study aims to increase our understanding of the effect of sex and age by applying five different statistical methods to evaluate the effect of these covariates on two independent TBI data sets representing patients from different geographical cohorts...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29042806/feeding-filaggrin-effects-of-l-histidine-supplementation-in-atopic-dermatitis
#10
Siao Pei Tan, Simon B Brown, Christopher Em Griffiths, Richard B Weller, Neil K Gibbs
Atopic dermatitis (AD), also known as eczema, is one of the most common chronic skin conditions worldwide, affecting up to 16% of children and 10% of adults. It is incurable and has significant psychosocial and economic impacts on the affected individuals. AD etiology has been linked to deficiencies in the skin barrier protein, filaggrin. In mammalian skin, l-histidine is rapidly incorporated into filaggrin. Subsequent filaggrin proteolysis releases l-histidine as an important natural moisturizing factor (NMF)...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/29042150/paul-joyce-and-the-infinite-alleles-model
#11
Stephen M Krone
Paul Joyce's work touched on a variety of topics in population genetics-from mathematical models of idealized systems to working closely with biologists on experimental evolution and landscape genetics. I will focus on his earlier mathematical/statistical work that centered on the infinite alleles model.
October 14, 2017: Theoretical Population Biology
https://www.readbyqxmd.com/read/29040834/effect-of-oil-structure-on-cyclodextrin-based-pickering-emulsions-for-bupivacaine-topical-application
#12
Jiun-Wen Hu, Mei-Wen Yen, Ae-June Wang, I-Ming Chu
Cyclodextrins (CDs) coupled with oils forms an insoluble inclusion complex that is able to adsorb to the interface between oils and aqueous phases; it thereby stabilizes Pickering emulsions. Three types of oils (triglyceride, linear chain oil, and ring-structured oil) were chosen to work with CDs to prepare bupivacaine (BPC)-encapsulated Pickering emulsions. We also investigated the relationship between oils and CDs; as well as their influences on stability, drug-releasing capability and skin permeability. Particle sizes and microstructures were determined by dynamic light scattering and scanning electron microscopy, respectively...
October 4, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29039888/which-is-best-method-for-instillation-of-topical-therapy-to-the-upper-urinary-tract-an-in-vivo-porcine-study-to-evaluate-three-delivery-methods
#13
Zhenbang Liu, Junxiang Ng, Arianto Yuwono, Yadong Lu, Yung Khan Tan
PURPOSE: To compare the staining intensity of the upper urinary tract (UUT) urothelium among three UUT delivery methods in an in vivo porcine model. MATERIALS AND METHODS: A fluorescent dye solution (indigo carmine) was delivered to the UUT via three different methods: antegrade perfusion, vesico-ureteral reflux via indwelling ureteric stent and retrograde perfusion via a 5F open-ended ureteral catheter. Twelve renal units were tested with 4 in each method. After a 2-hour delivery time, the renal-ureter units were harvested en bloc...
October 17, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29039223/predictors-of-excessive-use-of-social-media-and-excessive-online-gaming-in-czech-teenagers
#14
Jana Spilková, Pavla Chomynová, Ladislav Csémy
Background and aims Young people's involvement in online gaming and the use of social media are increasing rapidly, resulting in a high number of excessive Internet users in recent years. The objective of this paper is to analyze the situation of excessive Internet use among adolescents in the Czech Republic and to reveal determinants of excessive use of social media and excessive online gaming. Methods Data from secondary school students (N = 4,887) were collected within the 2015 European School Survey Project on Alcohol and Other Drugs...
October 17, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29039216/breast-cancer-screening-and-migrants-exploring-targeted-messages-for-moroccan-migrant-women-in-brussels
#15
Wanda Monika Johanna Van Hemelrijck, L Suzanne Suggs, Alessandra Agnese Grossi, Peter Schröder-Bäck, Katarzyna Czabanowska
OBJECTIVES: This study explored views of Moroccan migrant women on barriers and facilitators to the organized breast cancer screening program in Brussels (Belgium), and the potential of targeted printed invitations to increase this population's attendance to the program. METHODS: We conducted one expert interview with the breast cancer screening program coordinator on current practices and challenges with regards to inviting Moroccan migrant women in Brussels for screening...
October 17, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/29039104/in-vitro-and-in-vivo-methods-for-analysis-of-nanoparticle-potential-to-induce-delayed-type-hypersensitivity-reactions
#16
Timothy M Potter, Barry W Neun, Marina A Dobrovolskaia
Delayed-type hypersensitivity (DTH) reactions are among the common reasons for drug withdrawal from clinical use during the post-marketing stage. Several in vivo methods have been developed to test DTH responses in animal models. They include the local lymph node assay (LLNA) and local lymph node proliferation assay (LLNP). While LLNA is instrumental in testing topically administered formulations (e.g., creams), the LLNP was proven to be predictive of drug-mediated DTH in response to small molecule pharmaceuticals...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29038097/recommending-education-materials-for-diabetic-questions-using-information-retrieval-approaches
#17
Yuqun Zeng, Xusheng Liu, Yanshan Wang, Feichen Shen, Sijia Liu, Majid Rastegar-Mojarad, Liwei Wang, Hongfang Liu
BACKGROUND: Self-management is crucial to diabetes care and providing expert-vetted content for answering patients' questions is crucial in facilitating patient self-management. OBJECTIVE: The aim is to investigate the use of information retrieval techniques in recommending patient education materials for diabetic questions of patients. METHODS: We compared two retrieval algorithms, one based on Latent Dirichlet Allocation topic modeling (topic modeling-based model) and one based on semantic group (semantic group-based model), with the baseline retrieval models, vector space model (VSM), in recommending diabetic patient education materials to diabetic questions posted on the TuDiabetes forum...
October 16, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29038092/implications-of-attrition-in-a-longitudinal-web-based-survey-an-examination-of-college-students-participating-in-a-tobacco-use-study
#18
Bennett McDonald, Regine Haardoerfer, Michael Windle, Michael Goodman, Carla Berg
BACKGROUND: Web-based survey research has several benefits, including low cost and burden, as well as high use of the Internet, particularly among young adults. In the context of longitudinal studies, attrition raises concerns regarding the validity of data, given the potential associations with individual and institutional characteristics, or the focal area of study (eg, cigarette use). OBJECTIVES: The objective of this study was to compare baseline characteristics of nonresponders versus responders in a sample of young adult college students in a Web-based longitudinal study regarding tobacco use...
October 16, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/29037604/met-activation-and-physical-dynamics-of-the-metastatic-process-the-paradigm-of-cancers-of-unknown-primary-origin
#19
REVIEW
Giulia M Stella, Silvia Benvenuti, Alessandra Gentile, Paolo M Comoglio
The molecular and cellular mechanisms which drive metastatic spread are the topic of constant debate and scientific research due to the potential implications for cancer patients' prognosis. In addition to genetics and environmental factors, mechanics of single cells and physical interaction with the surrounding environment play relevant role in defining invasive phenotype. Reconstructing the physical properties of metastatic clones may help to clarify still open issues in disease progression as well as to lead to new diagnostic and therapeutic approaches...
September 21, 2017: EBioMedicine
https://www.readbyqxmd.com/read/29037415/dental-phenotypic-shape-variation-supports-a-multiple-dispersal-model-for-anatomically-modern-humans-in-southeast-asia
#20
Julien Corny, Manon Galland, Marta Arzarello, Anne-Marie Bacon, Fabrice Demeter, Dominique Grimaud-Hervé, Charles Higham, Hirofumi Matsumura, Lan Cuong Nguyen, Thi Kim Thuy Nguyen, Viet Nguyen, Marc Oxenham, Thongsa Sayavongkhamdy, François Sémah, Laura L Shackelford, Florent Détroit
The population history of anatomically modern humans (AMH) in Southeast Asia (SEA) is a highly debated topic. The impact of sea level variations related to the Last Glacial Maximum (LGM) and the Neolithic diffusion on past population dispersals are two key issues. We have investigated competing AMH dispersal hypotheses in SEA through the analysis of dental phenotype shape variation on the basis of very large archaeological samples employing two complementary approaches. We first explored the structure of between- and within-group shape variation of permanent human molar crowns...
November 2017: Journal of Human Evolution
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