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https://www.readbyqxmd.com/read/28721155/clinical-importance-of-epicardial-adipose-tissue
#1
Eszter Nagy, Adam L Jermendy, Bela Merkely, Pal Maurovich-Horvat
Different visceral fat compartments have several systemic effects and may play a role in the development of both insulin resistance and cardiovascular diseases. In the last couple of years special attention has been paid to the epicardial adipose tissue (EAT), which can be quantified by non-invasive cardiac imaging techniques. The epicardial fat is a unique fat compartment between the myocardium and the visceral pericardium sharing a common embryologic origin with the visceral fat depot. Epicardial adipose tissue has several specific roles, and its local effects on cardiac function are incorporated in the complex pathomechanism of coronary artery disease...
June 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28719906/a-common-ancestral-asn242ser-mutation-in-tmem67-identified-in-multiple-iranian-families-with-joubert-syndrome
#2
MohammadReza Dehghani, Majid Mojarad, Ehsan Ghayoor Karimiani, Mohammad Yahya Vahidi Mehrjardi, Afsaneh Sahebalzamani, Farah Ashrafzadeh, Mehran Beiraghi Toosi, Atiyeh Eslahi, Najmeh Ahangari, Seyed Mojtaba Yassini, Afsaneh Hassanbeigi, Azam Rasti, Seyed Mehdi Kalantar, Reza Maroofian
BACKGROUND: Joubert syndrome (JS) is a clinically and genetically heterogeneous group of rare neurodevelopmental disorder characterised by peculiar midbrain-hindbrain malformation, known as the "molar tooth" sign. JS can manifest a broad range of signs and symptoms. The most common features of JS are hypotonia, ataxia, developmental delay/intellectual disability, abnormal eye movements, and neonatal breathing abnormalities. To date, 29 genes have been shown to cause JS. METHODS: We employed whole-genome single nucleotide polymorphism genotyping in a group of Iranian families with JS and Sanger sequencing of a known mutation associated with JS located in a single homozygous regions shared by affected members of the families...
July 19, 2017: Public Health Genomics
https://www.readbyqxmd.com/read/28718807/melanin-and-melanin-related-polymers-as-materials-with-biomedical-and-biotechnological-applications-cuttlefish-ink-and-mussel-foot-proteins-as-inspired-biomolecules
#3
REVIEW
Francisco Solano
The huge development of bioengineering during the last years has boosted the search for new bioinspired materials, with tunable chemical, mechanical, and optoelectronic properties for the design of semiconductors, batteries, biosensors, imaging and therapy probes, adhesive hydrogels, tissue restoration, photoprotectors, etc. These new materials should complement or replace metallic or organic polymers that cause cytotoxicity and some adverse health effects. One of the most interesting biomaterials is melanin and synthetic melanin-related molecules...
July 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28717518/the-sharing-of-radiological-images-by-professional-mixed-martial-arts-fighters-on-social-media
#4
George Rahmani, Cormac W Joyce, Peter McCarthy
BACKGROUND: Mixed martial arts is a sport that has recently enjoyed a significant increase in popularity. This rise in popularity has catapulted many of these "cage fighters" into stardom and many regularly use social media to reach out to their fans. An interesting result of this interaction on social media is that athletes are sharing images of their radiological examinations when they sustain an injury. PURPOSE: To review instances where mixed martial arts fighters shared images of their radiological examinations on social media and in what context they were shared...
June 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/28713880/finding-street-gang-members-on-twitter
#5
Lakshika Balasuriya, Sanjaya Wijeratne, Derek Doran, Amit Sheth
Most street gang members use Twitter to intimidate others, to present outrageous images and statements to the world, and to share recent illegal activities. Their tweets may thus be useful to law enforcement agencies to discover clues about recent crimes or to anticipate ones that may occur. Finding these posts, however, requires a method to discover gang member Twitter profiles. This is a challenging task since gang members represent a very small population of the 320 million Twitter users. This paper studies the problem of automatically finding gang members on Twitter...
August 2016: Proc IEEE ACM Int Conf Adv Soc Netw Anal Min
https://www.readbyqxmd.com/read/28711120/from-efficacy-to-global-impact-lessons-learned-about-what-not-to-do-in-translating-our-research-to-reach
#6
Carolyn B Becker
Although members of the Association for Behavioral and Cognitive Therapies have made significant strides toward the collective goals outlined in our mission statement, we routinely acknowledge that our ability to develop empirically supported treatments exceeds our success in improving dissemination and implementation of said interventions. Further, as noted by Kazdin and Blase (2011), even if we succeeded in having every clinician worldwide administer our best treatments with excellent competency, we still would be unsuccessful in markedly impacting the worldwide burden of mental illness because most treatments require intensive labor by expensive providers...
September 2017: Behavior Therapy
https://www.readbyqxmd.com/read/28710057/images-of-little-cigars-and-cigarillos-on-instagram-identified-by-the-hashtag-swisher-thematic-analysis
#7
Jon-Patrick Allem, Patricia Escobedo, Kar-Hai Chu, Tess Boley Cruz, Jennifer B Unger
BACKGROUND: Little cigar and cigarillo use is becoming more prevalent in the United States and elsewhere, with implications for public health. As little cigar and cigarillo use grows in popularity, big social media data (eg, Instagram, Google Web Search, Twitter) can be used to capture and document the context in which individuals use, and are marketed, these tobacco products. Big social media data may allow people to organically demonstrate how and why they use little cigars and cigarillos, unprimed by a researcher, without instrument bias and at low costs...
July 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28709718/gadoxetic-acid-enhanced-high-temporal-resolution-hepatic-arterial-phase-imaging-with-view-sharing-technique-impact-on-the-li-rads-category
#8
Satoshi Goshima, Yoshifumi Noda, Kimihiro Kajita, Nobuyuki Kawai, Hiromi Koyasu, Hiroshi Kawada, Masayuki Matsuo, Kyongtae T Bae
PURPOSE: To evaluate the value of view-sharing multi-hepatic arterial-phase (mHAP) imaging for diagnosis of hypervascular hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Forty-seven consecutive patients with HCC underwent gadoxetic acid-enhanced magnetic resonance (MR) imaging before angiographic and lipiodol CT. Hepatic arterial-phase images were obtained at 5 consecutive phases with shared central k-space of 25%, followed by portal venous, late (2 and 3min), and hepatobiliary phase imaging...
July 3, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28709027/singlet-oxygen-triggers-chloroplast-rupture-and-cell-death-in-the-zeaxanthin-epoxidase-defective-mutant-aba1-of-arabidopsis-thaliana-under-high-light-stress
#9
Álvaro Sánchez-Corrionero, Inmaculada Sánchez-Vicente, Sergio González-Pérez, Ascensión Corrales, Anja Krieger-Liszkay, Óscar Lorenzo, Juan B Arellano
The two Arabidopsis thaliana mutants, aba1 and max4, were previously identified as sharing a number of co-regulated genes with both the flu mutant and Arabidopsis cell suspension cultures exposed to high light (HL). On this basis, we investigated whether aba1 and max4 were generating high amounts of singlet oxygen ((1)O2) and activating (1)O2-mediated cell death. Thylakoids of aba1 produced twice as much (1)O2 as thylakoids of max4 and wild type (WT) plants when illuminated with strong red light. (1)O2 was measured using the spin probe 2,2,6,6-tetramethyl-4-piperidone hydrochloride...
July 4, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28708774/identifying-unilateral-disease-in-chinese-patients-with-primary-aldosteronism-by-using-a-modified-prediction-score
#10
Ying Zhang, Wenquan Niu, Fangfang Zheng, Hua Zhang, Wenlong Zhou, Zhoujun Shen, Jianzhong Xu, Xiaofeng Tang, Jin Zhang, Ping-Jin Gao, Ji-Guang Wang, Limin Zhu
OBJECTIVE: The current study aimed to evaluate the role of Küpers' score in predicting unilateral aldosteronism, and develop a modified score in Chinese patients with primary aldosteronism. METHODS: The current retrospective study included 406 patients with primary aldosteronism who underwent successful adrenal venous sampling (AVS) and were divided into the unilateral (n = 211) and bilateral (n = 195) groups according to the AVS results. Normokalemia was noted in both the unilateral (n = 64) and bilateral groups (n = 84) when plasma and urinary aldosterone were measured...
July 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28707710/perception-and-image-of-dermatology-in-the-german-general-population-2002-2014
#11
M Augustin, L Eissing, P Elsner, K Strömer, I Schäfer, A Enk, M Reusch, R Kaufmann
BACKGROUND: In contrast to other European countries, dermatologists in Germany provide healthcare for a broad spectrum of diseases of the skin and mucous membranes. Current population-based data on the perception of dermatology were lacking to date. OBJECTIVE: Analysis of the perception of dermatology from the general population's perspective with regard to utilization, satisfaction, and responsibility. METHODS: Nation-wide survey on awareness, utilization, rating, and image of dermatology in Oct/2014 through computer-assisted telephone interviews on a representative sample of the adult general population (n = 1,015), performed by the FORSA institute...
July 14, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28707639/life-in-unexpected-places-employing-visual-thinking-strategies-in-global-health-training
#12
Jill Allison, Shree Mulay, Monica Kidd
BACKGROUND: The desire to make meaning out of images, metaphor, and other representations indicates higher-order cognitive skills that can be difficult to teach, especially in the complex and unfamiliar environments like those encountered in many global health experiences. Because reflecting on art can help develop medical students' imaginative and interpretive skills, we used visual thinking strategies (VTS) during an immersive 4-week global health elective for medical students to help them construct new understanding of the social determinants of health in a low-resource setting...
January 2017: Education for Health: Change in Training & Practice
https://www.readbyqxmd.com/read/28707180/a-social-needs-assessment-tool-for-an-urban-latino-population
#13
Beth A Careyva, Roya Hamadani, Timothy Friel, Cathy A Coyne
Unmet social needs contribute significantly to health outcomes, yet they are not routinely assessed in health care settings. Identifying modifiable social needs and feasible tools to assess them may improve health and decrease costs. We conducted 18 focus groups with 115 participants, stratified by age (18-35, 36-64, and 65+), ethnicity (Hispanic, non-Hispanic), and language (English, Spanish) to explore priority social needs, images to depict social need categories, and acceptability of a computer-based program to identify these needs...
July 13, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28705767/common-and-distinct-dysfunctional-patterns-contribute-to-triple-network-model-in-schizophrenia-and-depression-a-preliminary-study
#14
Yuchao Jiang, Mingjun Duan, Xi Chen, Xin Chang, Hui He, YingJia Li, Cheng Luo, Dezhong Yao
BACKGROUND: Schizophrenia (SCH) and depression (DEP) are prevalent psychiatric disorders and share common and distinguished elements in their pathophysiology. A triple network model composed of the default mode network (DMN), salience network (SN) and central executive network (CEN) may represent a major abnormality across several psychiatric disorders including SCH and DEP. However, common and distinct dysfunctional patterns between SCH and DEP across three core networks remain unclear...
July 10, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28704294/early-detection-of-neonatal-hypoxic-ischemic-white-matter-injury-an-mr-diffusion-tensor-imaging-study
#15
Youngseob Seo, Geun-Tae Kim, Jin Wook Choi
The purpose of this study was to compare diffusion tensor metrics in normal age-matched neonates with survivors of hypoxic-ischemic encephalopathy (HIE) and extracorporeal membrane oxygenation (ECMO). Thirty-five normal, 27 HIE, and 13 ECMO infants underwent MRI at 3 T. Neurodevelopmental assessments were performed. Fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) of the inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, anterior commissure, genu corpus callosum and splenium of the corpus callosum, anterior and posterior limb of the internal capsule, superior longitudinal fasciculus, and the centrum semiovale were analyzed with tract-based spatial statistics modified for use in neonates...
July 12, 2017: Neuroreport
https://www.readbyqxmd.com/read/28702350/reading-related-white-matter-structures-in-adolescents-are-influenced-more-by-dysregulation-of-emotion-than-behavior
#16
Tzipi Horowitz-Kraus, Scott K Holland, Amelia L Versace, Michele A Bertocci, Genna Bebko, Jorge R C Almeida, Susan B Perlman, Michael J Travis, Mary Kay Gill, Lisa Bonar, Claudiu Schirda, Jeffrey L Sunshine, Boris Birmaher, Gerry Taylor, Vaibhav A Diwadkar, Sarah M Horwitz, David Axelson, Thomas Frazier, Eugene L Arnold, Mary A Fristad, Eric A Youngstrom, Robert L Findling, Mary L Phillips
Mood disorders and behavioral are broad psychiatric diagnostic categories that have different symptoms and neurobiological mechanisms, but share some neurocognitive similarities, one of which is an elevated risk for reading deficit. Our aim was to determine the influence of mood versus behavioral dysregulation on reading ability and neural correlates supporting these skills in youth, using diffusion tensor imaging in 11- to 17-year-old children and youths with mood disorders or behavioral disorders and age-matched healthy controls...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28702112/patient-preference-for-transradial-access-over-transfemoral-access-for-cerebrovascular-procedures
#17
Sudhakar R Satti, Ansar Z Vance, Sohil N Golwala, Tim Eden
PURPOSE: Shared decision-making, when physicians and patients collaborate and agree on health care decisions, is a key tenant of patient-centered care. Choice of access site for neurovascular procedures is rarely a shared decision point between physicians and patients. We present our initial evaluation of patient preference for radial over femoral access for cerebrovascular procedures. MATERIALS AND METHODS: IRB approved single-center, prospective, and consecutive survey of all patients undergoing transradial access for cerebrovascular imaging and intervention...
June 2017: Journal of Vascular and Interventional Neurology
https://www.readbyqxmd.com/read/28700575/synaptic-organization-of-visual-space-in-primary-visual-cortex
#18
M Florencia Iacaruso, Ioana T Gasler, Sonja B Hofer
How a sensory stimulus is processed and perceived depends on the surrounding sensory scene. In the visual cortex, contextual signals can be conveyed by an extensive network of intra- and inter-areal excitatory connections that link neurons representing stimulus features separated in visual space. However, the connectional logic of visual contextual inputs remains unknown; it is not clear what information individual neurons receive from different parts of the visual field, nor how this input relates to the visual features that a neuron encodes, defined by its spatial receptive field...
July 12, 2017: Nature
https://www.readbyqxmd.com/read/28695820/research-advances-in-clinical-and-imaging-characteristics-of-intraductal-papillary-mucinous-neoplasm-of-the-bile-duct
#19
(no author information available yet)
Understanding on the intraductal papillary mucinous neoplasm of the pancreas (IPMN-P) has dramatically improved in the past three decades. A new disease named intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) reported in recent years shares several similar clinical features with IPMN-P. The clinical manifestations and imaging characteristics of IPMN-B have been gradually recognized. This review summarizes some of the typical cases reported since 2000 and find that clinical manifestations of IPMN-B include epigastric discomfort,biliary colic,jaundice,intermittent fever,sometimes without any symptoms; imaging triads for IPMN-B are mucobilia,dilated bile duct,and bile duct mural nodule...
June 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28693952/pathogenesis-of-adenomyosis-an-update-on-molecular-mechanisms
#20
REVIEW
Silvia Vannuccini, Claudia Tosti, Francisco Carmona, S Joseph Huang, Charles Chapron, Sun-Wei Guo, Felice Petraglia
Adenomyosis is a uterine disorder becoming more commonly diagnosed in women of reproductive age because of diagnostic imaging advancements. The new epidemiological scenario and the clinical evidence of pelvic pain, abnormal uterine bleeding and infertility are changing the classic perspective of adenomyosis as a premenopausal disease. In the last decade, the evaluation of multiple molecular mediators has improved our knowledge of pathogenic mechanisms of adenomyosis, supporting that this is an independent disease from endometriosis...
June 27, 2017: Reproductive Biomedicine Online
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