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https://www.readbyqxmd.com/read/29339065/accommodative-esotropia-treatment-plan-utilizing-simultaneous-strabismus-surgery-and-photorefractive-keratectomy
#1
H Sprague Eustis, Pulin Shah
PURPOSE: Accommodative esotropia is a common cause of acquired esotropia. Pathogenesis varies among patients but usually includes excessive hyperopia and a high accommodative convergence/accommodation ratio or tight medial recti. The present study reviews an individualized treatment plan combining photorefractive keratectomy (PRK) and strabismus surgery to correct these problems. DESIGN: This study is a retrospective, interventional case series. METHODS: Records for 15 patients who were treated for accommodative esotropia were reviewed...
January 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29296550/comparison-of-transepithelial-corneal-crosslinking-with-epithelium-off-crosslinking-epithelium-off-cxl-in-adult-pakistani-population-with-progressive-keratoconus
#2
Bushra Akbar, Rana Intisar-Ul-Haq, Mazhar Ishaq, Ayesha Fawad, Sabahat Arzoo, Kashif Siddique
PURPOSE: The purpose of this study is to compare the safety and efficacy of transepithelial corneal crosslinking (CXL) with epithelium-off crosslinking (epithelium-off CXL) in the treatment of progressive keratoconus in adult Pakistani population. MATERIALS AND METHODS: Sixty-four eyes of 64 consecutive patients of progressive keratoconus were included in this quasi-experimental study. Thirty-two eyes received transepithelial CXL with Peschke TE (0.25% riboflavin (Vitamin B2), 1...
October 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29275378/results-of-viscobubble-deep-anterior-lamellar-keratoplasty-after-failure-of-pneumatic-dissection
#3
Vincenzo Scorcia, Valentina De Luca, Andrea Lucisano, Adriano Carnevali, Giovanna Carnovale Scalzo, Cristina Bovone, Massimo Busin
AIM: To report the outcomes of bubble formation obtained by means of intrastromal injection of ophthalmic viscoelastic device (OVD) after failure of pneumatic dissection for deep anterior lamellar keratoplasty (DALK). METHODS: DALK was performed in 140 keratoconic eyes of 130 patients by injecting air and OVD only secondarily, after pneumatic dissection had failed; the bubble formation rates after air and OVD injection were recorded; complications, best spectacle-corrected visual acuity (BSCVA) and corneal tomographic parameters were evaluated 3 months, 6 months and 12 months postoperatively, as well as after complete suture removal...
December 23, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29227512/efficacy-and-safety-comparison-between-suberoylanilide-hydroxamic-acid-and-mitomycin-c-in-reducing-the-risk-of-corneal-haze-after-prk-treatment-in-vivo
#4
Govindaraj Anumanthan, Ajay Sharma, Michael Waggoner, Chuck W Hamm, Suneel Gupta, Nathan P Hesemann, Rajiv R Mohan
PURPOSE: This study compared the efficacy and safety of suberoylanilide hydroxamic acid (SAHA) and mitomycin C (MMC) up to 4 months in the prevention of corneal haze induced by photorefractive keratectomy (PRK) in rabbits in vivo. METHODS: Corneal haze in rabbits was produced with -9.00 diopter PRK. A single application of SAHA (25 μM) or MMC (0.02%) was applied topically immediately after PRK. Effects of the two drugs were analyzed by slit-lamp microscope, specular microscope, TUNEL assay, and immunofluorescence...
December 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29216872/late-onset-diffuse-lamellar-keratitis-4%C3%A2-years-after-femtosecond-laser-assisted-small-incision-lenticule-extraction-a-case-report
#5
Meiyan Li, Dong Yang, Yingjun Chen, Meng Li, Tian Han, Xingtao Zhou, Katherine Ni
BACKGROUND: To report a first case of late-onset diffuse lamellar keratitis (DLK) occurring 4 years after femtosecond laser-assisted small incision lenticule extraction (SMILE). CASE PRESENTATION: A 41-year-old man who underwent SMILE 4 years prior developed DLK in the right eye 1 day after he was struck in the eye by a finger while playing with his son. Slim-lamp microscopy and anterior segment optical coherence tomography (AS-OCT) were used to evaluate the cornea of the right eye...
December 8, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29200817/evaluation-of-corneal-symmetry-after-uv-corneal-crosslinking-for-keratoconus
#6
Hanan Mofty, Khaled Alzahrani, Fiona Carley, Sophie Harper, Arun Brahma, Leon Au, Debbie Morley, M Chantal Hillarby
Purpose: The purpose of this study was to assess UV corneal crosslinking (CXL) treatment outcomes for keratoconus by evaluating the corneal regularity in patients through follow-up using the Oculus Pentacam. Patients and methods: A total of 18 eyes from CXL patients with keratoconus were studied before and after CXL treatment, and six eyes from six patients who were not treated with CXL served as controls. Treated patients had Pentacam images taken before CXL treatment and regularly 3 months post treatment up to the 12th month...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29189945/could-adverse-effects-and-complications-of-selective-laser-trabeculoplasty-be-decreased-by-low-power-laser-therapy
#7
REVIEW
Alexandre de Carvalho Mendes Paiva, Adenilson de Souza da Fonseca
Selective laser trabeculoplasty (SLT) has been used for treatment of primary open-angle glaucoma, ocular hypertension, pigmenter and pseudoexfoliative glaucoma being considered a low-risk procedure. Therefore, transitory and permanent adverse effects have been reported, including corneal changes, subclinical edema, and reduction in endothelial cells and in central corneal thickness. Despite rarer, serious corneal complications after SLT can be permanent and lead to visual impairment, central corneal haze, opacity and narrowing...
November 30, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29180340/-association-between-hepatocyte-growth-factor-in-tears-and-corneal-haze-in-rabbits-early-after-epipolis-laser-in-situ-keratomileusis
#8
Jing Chen, Su-Ning Han, Xiu-Lan Zou, Yu-Ping Zou
OBJECTIVE: To study the dynamic changes of levels of hepatocyte growth factor (HGF) in tears and their association with corneal haze in rabbits early after epipolis laser in situ keratomileusis (Epi-LASIK). METHODS: Twenty-four New Zealand rabbits received Epi-LASIK with an ablation depth of 100 µm in one eye and of 150 µm in the other eye. Before and at 3, 7, 14, and 30 days after the surgery, the level of HGF in tears collected from the rabbits was measured using enzyme-linked immunosorbent assay (ELISA), and corneal haze was graded after surgery...
November 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/29141390/-the-clinical-analysis-of-corneal-interface-fluid-syndrome-after-laser-lamellar-corneal-refractive-surgery
#9
K J Lin, J Chen, W Lin, X D Lin, Y M Zhou, L D Zheng, Y Tong
Objective: To analysis, the clinical characteristics, refractive changes, and clinical treatment of interface fluid syndrome after laser lamellar corneal refractive surgery. Methods: During Dec. 2010 to Apr. 2016. In total 6 cases(9 eyes), 3 cases were bilateral, 3 cases were unilateral. Five patients were male and 1 was female. The age of the patients ranged from 20 to 29 years was (24.83±4.02) years. Six cases(9 eyes)of IFS were diagnosed at our hospital. The history and complete ophthalmic examination that include Slit-lamp examination, Slit-lamp photography, refraction, corneal thickness measurement, corneal endothelial cell counting, IOP, anterior segment OCT(AS-OCT), exams were recorded...
November 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29111069/chitosan-and-thiolated-chitosan-novel-therapeutic-approach-for-preventing-corneal-haze-after-chemical-injuries
#10
Forouhe Zahir-Jouzdani, Mirgholamreza Mahbod, Masoud Soleimani, Faezeh Vakhshiteh, Ehsan Arefian, Saeed Shahosseini, Rasoul Dinarvand, Fatemeh Atyabi
Corneal haze, commonly caused by deep physical and chemical injuries, can greatly impair vision. Growth factors facilitate fibroblast proliferation and differentiation, which leads to haze intensity. In this study, the potential effect of chitosan (CS) and thiolated-chitosan (TCS) nanoparticles and solutions on inhibition of fibroblast proliferation, fibroblast to myofibroblast differentiation, neovascularization, extracellular matrix (ECM) deposition, and pro-fibrotic cytokine expression was examined. Transforming growth factor beta-1 (TGFβ1) was induced by interleukin-6 (IL6) in human corneal fibroblasts and expression levels of TGFβ1, Platelet-derived growth factor (PDGF), α-smooth muscle actins (α-SMA), collagen type I (Col I), fibronectin (Fn) and vascular endothelial growth factor (VEGF) were quantified using qRT-PCR...
January 1, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29103962/corneal-stroma-enhancement-with-decellularized-stromal-laminas-with-or-without-stem-cell-recellularization-for-advanced-keratoconus
#11
Jorge L Alió Del Barrio, Mona El Zarif, Albert Azaar, Nehman Makdissy, Charbel Khalil, Walid Harb, Ibrahim El Achkar, Ziad Abdul Jawad, María P de Miguel, Jorge L Alió
PURPOSE: Phase-1 study to preliminarily evaluate the safety and efficacy of decellularized human corneal stromal lamina transplantation with or without autologous adipose derived adult stem cells (ADASC) recellularization within the corneal stroma of patients with advanced keratoconus. DESIGN: Phase one clinical trial METHODS: Femtosecond-assisted 120μm-thickness and 9mm-diameter laminas were obtained from the anterior stroma of human donor corneas and decellularized with a sodium dodecyl sulfate solution...
November 2, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29082123/ocular-surface-chemical-injury-treated-by-regenerating-agent-rgta-cacicol20
#12
Melih Ustaoglu, Nilgun Solmaz, Feyza Onder
Objective: To present the successful outcome of regenerating agent (RGTA) treatment in a patient with severe ocular surface chemical injury. Methods: Case report Results: A 14-year-old female patient was admitted to our clinic following chemical burn in the left eye. Her best corrected visual acuity (BCVA) was 20/40; and she had total corneal and 75% conjunctival epithelial loss, corneal haze, and limbal ischemia for nine clock hours in the left eye. The patient had already received standard therapy consisting of patching, preservative-free artificial tears, topical netilmicin, topical dexamethasone, oral doxycycline, and vitamin C for two weeks...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/29067107/conventional-vs-pulsed-light-accelerated-corneal-collagen-cross-linking-for-the-treatment-of-progressive-keratoconus-12-month-results-from-a-prospective-study
#13
Liang-Zhu Jiang, Wei Jiang, Shi-Yan Qiu
The aim of the present study was to compare the clinical outcomes of conventional corneal collagen cross-linking (CXL) and pulsed-light accelerated CXL (pl-ACXL) in the eyes of patients with progressive keratoconus. A total of 72 eyes with progressive keratoconus in 58 patients were equally divided into the CXL and pl-ACXL treatment groups. The CXL treatment was performed using the UVX 1000 system with 0.1% riboflavin solution in 20% dextran presoak for 30 min, and 3 mW/cm2 ultraviolet A (UVA) light for 30 min...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29019068/early-epithelial-complications-of-accelerated-trans-epithelial-corneal-crosslinking-in-treatment-of-keratoconus-a-case-series
#14
Sharon S W Chow, Tommy C Y Chan, Ian Y H Wong, Michelle C Y Fan, Jimmy S M Lai, Alex L K Ng
BACKGROUND: To report a case series of early postoperative complications following combined accelerated corneal crosslinking (CXL) and trans-epithelial technique in keratoconus. CASE PRESENTATIONS: Eleven eyes underwent accelerated trans-epithelial CXL (18 mW/cm2 for 5 min). Seven eyes (64%) developed complications in the first week postoperatively. Five eyes had large epithelial defects, and two eyes were complicated with diffuse punctate epithelial erosions...
October 10, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29018762/visual-performance-after-excimer-laser-photorefractive-keratectomy-for-high-myopia
#15
Yu-Ling Liu, Chien-Chi Tseng, Chang-Ping Lin
PURPOSE: To evaluate the efficacy, safety, predictability, and visual performance of excimer laser photorefractive keratectomy (PRK) for myopia greater than -8 diopters (D). METHODS: Fifty-four patients (104 eyes) with myopia from -8D to -13D and cylinder up to -4D received surface ablation technique with the Allegretto wave version 1009-1 excimer laser to correct their refractive error. The patients were examined on days 1, 3, 7, and 14 and 1, 3, 6, and 12 months postoperatively...
April 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/28985815/young-donor-graft-assisted-endothelial-keratoplasty-pdek-dmek-with-epithelial-debridement-for-chronic-pseudophakic-bullous-keratopathy
#16
Amar Agarwal, Priya Narang, Dhivya A Kumar, Ashvin Agarwal
OBJECTIVE: The aim of this study was to describe the applicability and report visual outcomes for the treatment of subepithelial fibrosis and anterior stromal scarring in cases of chronic pseudophakic bullous keratopathy (PBK) with epithelial debridement and endothelial keratoplasty (EK) (pre-Descemet endothelial keratoplasty [PDEK]; Descemet membrane endothelial keratoplasty [(DMEK]) using young donor tissue. DESIGN: Prospective, single-centre, interventional study...
October 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28945648/clinical-study-of-mitomycin-c-in-reducing-haze-formation-after-ultraviolet-a-riboflavin-crosslinking-for-keratoconus
#17
Linlin Xu, Xiangchen Tao, Zhiwei Li, Yanyun Xu, Wei Zhu, Huijuan Xu, Wei Pu, Yi Xie, Guoying Mu
OBJECTIVES: To evaluate the safety and efficacy of mitomycin C (MMC) in haze formation after ultraviolet A/riboflavin corneal crosslinking (CXL) for progressive keratoconus. METHODS: A total of 60 keratoconic eyes of 48 patients were enrolled in this prospective comparative study after obtaining informed consent. In the CXL group, standard corneal CXL was performed, whereas in the CXL+MMC group, 0.02% MMC was used for 30 s soon after CXL. Comprehensive ophthalmologic examinations were performed on all patients before surgery and at 1, 3, 6, and 12 months after surgery...
September 21, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28894403/corneal-cell-morphology-in-keratoconus-a-confocal-microscopic-observation
#18
Somnath Ghosh, Haliza Abdul Mutalib, Sharanjeet Kaur, Rituparna Ghoshal, Shamala Retnasabapathy
PURPOSE: To evaluate corneal cell morphology in patients with keratoconus using an in vivo slit scanning confocal microscope. METHODS: A cross-sectional study was conducted to evaluate the corneal cell morphology of 47 keratoconus patients and 32 healthy eyes without any ocular disease. New keratoconus patients with different disease severities and without any other ocular co-morbidity were recruited from the ophthalmology department of a public hospital in Malaysia from June 2013 to May 2014...
March 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28872519/changes-in-corneal-density-after-accelerated-corneal-collagen-cross-linking-with-different-irradiation-intensities-and-energy-exposures-1-year-follow-up
#19
Semra Akkaya Turhan, Ebru Toker
PURPOSE: To determine and compare the changes in corneal density after 2 different protocols of accelerated corneal collagen cross-linking (A-CXL) in patients with progressive keratoconus. METHODS: Two groups of eyes received A-CXL treatment; 20 eyes received A-CXL using continuous UVA light exposure at 9 mW/cm for 10 minutes with a total energy dose of 5.4 J/cm, and 24 eyes received A-CXL using continuous UVA light exposure at 30 mW/cm for 4 minutes with a total energy dose of 7...
August 31, 2017: Cornea
https://www.readbyqxmd.com/read/28827430/topical-ayurvedic-ointment-induced-chemical-injury-presenting-as-bilateral-acute-keratitis
#20
Pranita Sahay, Gunjan Saluja, Prafulla Kumar Maharana, Jeewan S Titiyal
A 40-years-old female patient was referred to the cornea clinic as a probable case of bilateral keratitis. The patient had a history of headache followed by acute onset of redness, pain and discharge from both eyes for 15 days. The patient was diagnosed as bilateral keratitis by the first contact physician and was started on topical antibiotics, cycloplegics and lubricating eye-drops. At presentation, both eyes had visual acuity of perception of light, conjunctival congestion, limbal blanching, diffuse corneal oedema and epithelial defect...
August 20, 2017: BMJ Case Reports
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