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https://www.readbyqxmd.com/read/28097917/repeatability-of-whole-cornea-measurements-using-an-anterior-segment-imaging-device-based-on-oct-and-placido-disk
#1
Noelia Martínez-Albert, José J Esteve-Taboada, Robert Montés-Micó
AIM: To evaluate the repeatability of topographic measurements using an integrated Placido disk - OCT device. METHODS: Thirty right eyes of thirty healthy subjects aged between 20 and 30 years were included. The topographic parameters of simulated keratometry, asphericity, minimum pachymetry, white-to-white distance, spherical aberration and corneal elevation were studied. Three measurements were taken by the same observer using the Visante omni device. The coefficient of repeatability (CoR), coefficient of variation (CoV) and intraclass correlation coefficient (ICC) were calculated to assess the repeatability...
January 18, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28095867/effects-of-ablation-depth-and-repair-time-on-the-corneal-elastic-modulus-after-laser-in-situ-keratomileusis
#2
Xiaojun Wang, Xiaona Li, Weiyi Chen, Rui He, Zhipeng Gao, Pengfei Feng
BACKGROUND: The biomechanical properties of the cornea should be taken into account in the refractive procedure in order to perform refractive surgery more accurately. The effects of the ablation depth and repair time on the elastic modulus of the rabbit cornea after laser in situ keratomileusis (LASIK) are still unclear. METHODS: In this study, LASIK was performed on New Zealand rabbits with different ablation depth (only typical LASIK flaps were created; residual stroma bed was 50 or 30% of the whole cornea thickness respectively)...
January 17, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28089285/thick-keratoconic-cornea-associated-with-posterior-polymorphous-corneal-dystrophy
#3
K Zaarour, E Slim, J Antoun, N Waked
INTRODUCTION: We herein report a case of bilateral unusually thick non-edematous keratoconic corneas with associated endothelial features of posterior polymorphous corneal dystrophy (PPCD). CASE REPORT: We report the case of a 27-year-old myopic woman who presented for refractive surgery. Slit lamp exam showed bilateral corneal protrusion with diffuse deep stromal and endothelial vesicular opacities and small paracentral bands. Topography showed generalized advanced corneal steepening in both eyes with increased anterior and posterior central corneal elevations in comparison to the best fit sphere...
January 12, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28069281/-effect-of-donor-graft-characteristics-on-clinical-outcomes-in-descemet-stripping-automated-endothelial-keratoplasty-dsaek
#4
G Ho Wang Yin, M Sampo, S Soare, L Hoffart
INTRODUCTION: The purpose of our study was to evaluate the progression of lamellar corneal grafts after endothelial keratoplasty by Descemet stripping automated endothelial keratoplasty (DSAEK) and the effect of their characteristics on the clinical and functional results. MATERIALS AND METHODS: This was a prospective study in which 74 patients who had undergone endothelial keratoplasty by DSAEK were included. The corneal grafts were obtained from a French tissue bank and were delivered in a preservation medium containing a deturgescent agent (Corneajet(®) or Stemalpha 3(®))...
January 6, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28068950/corneal-hysteresis-in-patients-with-glaucoma-like-optic-discs-ocular-hypertension-and-glaucoma
#5
Melissa L Murphy, Olya Pokrovskaya, Marie Galligan, Colm O'Brien
BACKGROUND: To compare corneal hysteresis (CH) measurements between patients with glaucoma, ocular hypertension (OHT) and glaucoma-like optic discs (GLD)- defined as a cup to disc ratio greater than or equal to 0.6 with normal intraocular pressure (IOP) and visual fields. The secondary aim was to investigate whether corneal resistance factor (CRF) and central corneal thickness (CCT) differ between patient groups. METHODS: In this cross sectional study a total of 123 patients (one eye each) were recruited from a glaucoma outpatient department to undergo ocular response analyser (ORA) testing and ultrasound pachymetry as well as clinical examination...
January 10, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28060059/efficacy-of-intrastromal-corneal-ring-segments-combined-with-flash-collagen-cross-linking-in-keratoconus
#6
Carlos H Gordillo, Juan C Grandin, Roger Zaldivar, Roberto Zaldivar, Adriana C Lotfi
PURPOSE: To evaluate outcomes, efficacy, and safety of intrastromal corneal ring segment implantation for treatment of keratoconus combined with collagen cross-linking (CXL) with 1-year follow-up. METHODS: One hundred nineteen eyes of 82 patients with keratoconus (37 females) underwent femtosecond (Intralase FS; Abbott Medical Optics, Inc) laser-assisted intrastromal corneal ring segment implantation (INTRASEG; Gamma Vision) with flash CXL (18 mW/cm for 5 minutes)...
February 2017: Cornea
https://www.readbyqxmd.com/read/28050086/management-of-recurrent-acute-bilateral-corneal-endotheliitis-monitored-by-serial-corneal-pachymetry
#7
B V Rao, Devika S Joshi, Sandeep Gupta, P S Moulick
No abstract text is available yet for this article.
December 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28029294/corneal-thickness-of-eyes-of-healthy-goats-sheep-and-alpacas-manually-measured-by-use-of-a-portable-spectral-domain-optical-coherence-tomography-device
#8
Alexander J LoPinto, Chris G Pirie, Daniela Bedenice, Sandra L Ayres
OBJECTIVE To determine corneal thickness of eyes of healthy goats, sheep, and alpacas by use of a portable spectral-domain optical coherence tomography (SD-OCT) device and evaluate intraoperator reliability for measurements. ANIMALS 11 female goats, 10 female sheep, and 11 (4 males and 7 females) alpacas. PROCEDURES Each animal was sedated, and gentle manual restraint was used to ensure proper positioning of the head and globe. Corneal pachymetry was performed (in triplicate) with a portable SD-OCT device on both eyes of each animal...
January 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28025794/alterations-in-corneal-epithelial-thickness-in-patients-with-congenital-myogenic-eyelid-ptosis
#9
Aysun Sanal Dogan, Mutlu Acar, Mustafa Kosker, Nese Arslan, Canan Gurdal
PURPOSE: To evaluate whether the corneal epithelial thickness (CET) maps obtained by optical coherence tomography (OCT) of the congenital myogenic eyelid ptosis differ from controls. METHODS: CET maps of 13 patients with congenital myogenic eyelid ptosis (m/f = 9/4; mean age 20.5 ± 7.5) and randomly selected one eye of 13 controls (m/f = 7/6; mean age 21.5 ± 6.5) were investigated. Three pachymetry scans of each eye were performed by OCT (RTVue-XR, Optovue Inc...
December 26, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/28003782/corneal-endothelial-cell-density-in-healthy-caucasian-population
#10
Rahmi Duman, Mediha Tok Çevik, Sadık Görkem Çevik, Reşat Duman, İrfan Perente
AIM: To reveal the changes of corneal endothelial characteristics with aging among Caucasian population. METHODS: Non-contact specular microscopy was performed in 564 eyes of 282 healthy Caucasian Turkish patients. Endothelial cell density (MCD), mean cell area (MCA), coefficient of variation (CV) in cell size, percentage of hexagonal cells, and central corneal thickness (CCT) were measured. RESULTS: The mean age was 42 ± 17.1 (6-85) years...
October 2016: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28003737/comparison-of-goldmann-applanation-tonometry-and-pascal-dynamic-contour-tonometry-in-relation-to-central-corneal-thickness-and-corneal-curvature
#11
Konstantinos Andreanos, Chryssanthi Koutsandrea, Dimitris Papaconstantinou, Andreas Diagourtas, Andreas Kotoulas, Panagiotis Dimitrakas, Marilita M Moschos
PURPOSE: The aim of the study was to assess the influence of central corneal thickness (CCT) and corneal curvature in tonometry measurements taken by Goldmann applanation tonometry (GAT) and Pascal dynamic contour tonometry (DCT). METHODS: This was a prospective study of 185 eyes from 97 subjects, attending outpatient ophthalmology appointments, who underwent intraocular pressure measurements by GAT and Pascal DCT. CCT and corneal curvature were obtained using ultrasound pachymetry and Orbscan topography, respectively...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27993593/repeatability-and-agreement-of-orbscan-ii-pentacam-hr-and-galilei-tomography-systems-in-corneas-with-keratoconus
#12
Jay J Meyer, Akilesh Gokul, Hans R Vellara, Zak Prime, Charles Nj McGhee
PURPOSE: To assess the repeatability and agreement of keratometry and pachymetry measurements obtained using three tomographers in eyes with keratoconus. DESIGN: Reliability analysis. METHODS: Setting: Institutional. STUDY POPULATION: 50 eyes of 50 participants with keratoconus. Observational Procedure: Steep keratometry, flat keratometry, central corneal thickness (CCT), and thinnest corneal thickness (TCT) measurements using Galilei, Orbscan II, and Pentacam HR...
December 16, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27984362/efficacy-of-intrastromal-corneal-ring-segments-combined-with-flash-collagen-cross-linking-in-keratoconus
#13
Carlos H Gordillo, Juan C Grandin, Roger Zaldivar, Roberto Zaldivar, Adriana C Lotfi
PURPOSE: To evaluate outcomes, efficacy, and safety of intrastromal corneal ring segment implantation for treatment of keratoconus combined with collagen cross-linking (CXL) with 1-year follow-up. METHODS: One hundred nineteen eyes of 82 patients with keratoconus (37 females) underwent femtosecond (Intralase FS; Abbott Medical Optics, Inc) laser-assisted intrastromal corneal ring segment implantation (INTRASEG; Gamma Vision) with flash CXL (18 mW/cm for 5 minutes)...
December 14, 2016: Cornea
https://www.readbyqxmd.com/read/27982210/comparison-of-central-corneal-thickness-estimated-by-an-ultrasonic-pachymeter-and-non-contact-specular-microscopy
#14
Sadık Görkem Çevik, Rahmi Duman, Mediha Tok Çevik, Sertaç Argun Kıvanç, Berna Akova-Budak, Irfan Perente, Resat Duman
Purpose: To compare central corneal thickness (CCT) measurements of healthy individuals obtained with ultrasonic pachymetry (UP) and non-contact specular microscopy (NCSM). Method: In total, 148 eyes of 74 subjects with no ocular or systemic diseases were included in the study. Central corneal thickness measurements of all patients performed with UP and NCCM were compared. Results: A total of 74 subjects (38 females) were included in this study...
September 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/27958215/congenital-keratoglobus-with-blue-sclera-in-two-siblings-with-overlapping-marshall-stickler-phenotype
#15
Serhat Imamoglu, Vedat Kaya, Ebru Yalin Imamoglu, Kemran Gok
We aimed to describe congenital keratoglobus with blue sclera in two siblings with overlapping Marshall/Stickler phenotype. Two sisters (ages four and six) with bilateral high astigmatism were evaluated by slit-lamp microscopy. Corneal topography and pachymetry maps were also obtained. Slit-lamp examination revealed that both corneas were globular in shape with peripheral corneal thinning. Pachymetry maps showed diffuse corneal thinning. Two siblings had in common the features of keratoglobus, blue sclera, atypical face, hearing loss, and hypermobile joints...
November 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27951595/corneal-endothelial-cell-migration-and-proliferation-enhanced-by-rho-kinase-rock-inhibitors-in-in-vitro-and-in-vivo-models
#16
Landon C Meekins, Noel Rosado-Adames, Rupalatha Maddala, Jiagang J Zhao, Ponugoti V Rao, Natalie A Afshari
Purpose: To explore the role of Rho-associated kinases (ROCK) in corneal physiology and regeneration, and the effects of suppressing its activity in stimulating corneal endothelial cell proliferation and migration in vitro and in vivo. Methods: Immunohistochemistry was performed to detect RhoA and ROCK-1 and ROCK-2 in human corneal tissue. Adult porcine corneal endothelial cells (CECs) were isolated, grown to confluence, and further characterized. Under the treatment of ROCK inhibitors, changes in the cellular distribution profile of ZO-1 and F-actin were examined by immunofluorescence staining...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27941386/ten-year-clinical-outcome-of-the-first-patient-undergoing-descemet-membrane-endothelial-keratoplasty
#17
Lamis Baydoun, Thomas Müller, Itay Lavy, Jack Parker, Marina Rodriguez-Calvo-de-Mora, Vasilios S Liarakos, Isabel Dapena, Gerrit R J Melles
PURPOSE: To describe the 10-year clinical outcome of the first patient worldwide who underwent Descemet membrane endothelial keratoplasty (DMEK). METHODS: In 2006, a 63-year-old man presented at the Melles Cornea Clinic, Rotterdam, with bilateral Fuchs endothelial dystrophy and cataract. After phacoemulsification, in vivo DMEK was performed in the left eye and 10 months later in the right eye. Best spectacle-corrected visual acuity (BSCVA), endothelial cell density, pachymetry, and complications were recorded every 6 months over a 10-year period...
December 8, 2016: Cornea
https://www.readbyqxmd.com/read/27930789/comparison-of-corneal-riboflavin-gradients-using-dextran-and-hpmc-solutions
#18
Tobias Ehmke, Theo G Seiler, Isaak Fischinger, Tammo Ripken, Alexander Heisterkamp, Beatrice E Frueh
PURPOSE: To determine the riboflavin concentration gradient in the anterior corneal stroma when using hydroxypropyl methylcellulose (HPMC) or dextran as the carrier agent. METHODS: Four different groups of porcine corneas (5 each) were compared regarding the riboflavin concentration in the anterior stroma. Prior to all experiments, stable hydration conditions were established for the corresponding solution. The dextran groups were treated with 0.1% riboflavin in 20% dextran for 10 and 30 minutes and the HPMC groups with 0...
December 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27891366/evaluation-of-the-central-corneal-thickness-with-anterior-segment-optical-coherence-tomogram-after-penetrating-keratoplasty
#19
Anuradha Raj, Renu Dhasmana, Harsh Bahadur, Ramesh Chander Nagpal
INTRODUCTION: Graft central thickness evaluates the graft quality which affects the outcome of Penetrating Keratoplasty (PK). It varies at different point of time after PK. Anterior Segment Optical Coherence Tomography (ASOCT) can measure graft's central thickness with quite high precision. AIM: The purpose of the study was to monitor the Central Corneal thickness (CCT) with ASOCT after PK and to evaluate its relationship with the pre-operative diagnosis. MATERIALS AND METHODS: This is an observational retrospective study where records of optical PK done in December 2012 and June 2015 were reviewed...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27878429/comparison-of-specular-microscopy-and-ultrasound-pachymetry-before-and-after-cataract-surgery
#20
Alberto López-Miguel, María Sanchidrián, Itziar Fernández, Alfredo Holgueras, Miguel J Maldonado
PURPOSE: To compare specular microscopy (Topcon SP-3000P, Topcon Corporation, Tokyo, Japan) and ultrasound (US) technology when evaluating central corneal thickness (CCT) prior to and after phacoemulsification. METHODS: Corneal edema was assessed in phacoemulsification patients due to senile cataract by measuring CCT preoperatively and 1 day, 1 month, and 3 months postoperatively. Bland-Altman analysis was performed to assess interchangeability between pachymetry techniques for each visit...
November 22, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
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