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Lasik Ectasia

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https://www.readbyqxmd.com/read/28379654/corneal-collagen-crosslinking-for-post-lasik-ectasia-an-australian-study
#1
Jessica Y Tong, Deepa Viswanathan, Christopher Hodge, Gerard Sutton, Colin Chan, John J Males
PURPOSE: Post laser-assisted in situ keratomileusis (LASIK) ectasia is a rare and unpredictable complication after LASIK. Corneal collagen crosslinking (CXL) has emerged as a promising technique to address this complication. Our study evaluates the long-term efficacy of CXL for post-LASIK ectasia in an Australian setting. DESIGN: Retrospective review of post-LASIK ectasia patients referred to and treated at 3 corneal refractive surgery institutions in Sydney, Australia...
March 29, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28355171/glaucoma-mini-shunt-implantation-after-keratoplasty
#2
Jasbeth Ledesma-Gil, María de Los Ángeles García-Rodríguez, Lulu U Gurria, Enrique O Graue-Hernández, Alejandro Navas
PURPOSE: To report the outcomes of patients who underwent miniature glaucoma shunt implantation after secondary glaucoma due to keratoplasty. MATERIALS AND METHODS: Prospective study of consecutive clinical cases who underwent mini-glaucoma shunt implantation following keratoplasty. In brief, a fornix-based conjunctival flap was performed, approximately 50% thickness scleral flap. Mitomycin C 0.025% placed under Tenon's capsule. A 25-G needle created entry for mini-shunt...
April 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28317666/transepithelial-crosslinking-retreatment-of-progressive-corneal-ectasia-unresponsive-to-classic-crosslinking
#3
Roy S Rubinfeld, Rachel H Epstein, Parag A Majmudar, Deborah Kim, Michael Choi, Randy J Epstein
A 41-year-old man presented 10 years after uneventful laser in situ keratomileusis (LASIK) with symptomatic post-LASIK ectasia. He had treatment with the classic Dresden epithelium-off technique and presented 4 years later with progression of the ectasia. He was subsequently retreated with conductive keratoplasty (CK) followed by a new proprietary epithelium-on corneal collagen crosslinking (CXL) procedure using a proprietary transepithelial riboflavin formulation and delivery system on the following day...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28192838/topography-guided-prk-and-crosslinking-in-eyes-with-keratoconus-and-post-lasik-ectasia
#4
T M Müller, A P Lange
Topography-guided photorefractive keratectomy (TG-PRK) combined with corneal collagen crosslinking (CXL) has been shown to potentially improve vision and stabilize progression in patients with keratoconus (KC). We attempted to reproduce the previously published results using a different laser platform (AMARIS 500E) in patients with KC and post-LASIK ectasia (PLE). All of the 9 included eyes showed improved topography (Kmax, Kmean, RMS HOA, vertical coma, cylinder; p < 0.05) and improved visual acuity (BCVA, UCVA; p < 0...
February 13, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28168049/photorefractive-keratectomy-for-residual-myopia-after-myopic-laser-in-situ-keratomileusis
#5
Kamal A M Solaiman, Sameh M Fouda, Ashraf Bor'i, Haitham Y Al-Nashar
Purpose. To evaluate the safety, efficacy, and predictability of photorefractive keratectomy (PRK) on the corneal flap for correction of residual myopia following myopic laser in situ keratomileusis (LASIK). Patients and Methods. A retrospective study on eyes retreated by PRK on the corneal flap for residual myopia after LASIK. All eyes had no enough stroma after LASIK sufficient for LASIK enhancement. Data included spherical equivalent (SE), uncorrected and best corrected visual acuity (UCVA and BCVA), central pachymetry, corneal higher order aberrations (HOAs), corneal hysteresis (CH), corneal resistance factor (CRF), and corneal haze...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28068447/corneal-ectasia-after-lasik-combined-with-prophylactic-corneal-cross-linking
#6
Suphi Taneri, Saskia Kiessler, Anika Rost, H Burkhard Dick
PURPOSE: To report a case of unilateral corneal ectasia following LASIK surgery combined with prophylactic corneal cross-linking (CXL) in a young patient. METHODS: Case report. RESULTS: Preoperative topography was unremarkable in both eyes with a minimum corneal thickness of 554 μm in the right eye and 546 μm in the left eye. Preoperative corrected distance visual acuity (CDVA) was 1.0 (20/20 Snellen) in both eyes with a refraction of +1...
January 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28031696/under-flap-stromal-bed-cxl-for-early-post-lasik-ectasia-a-novel-treatment-technique
#7
Avi Wallerstein, Eser Adiguzel, Mathieu Gauvin, Nima Mohammad-Shahi, Mark Cohen
PURPOSE: Collagen cross-linking (CXL) for post-laser-assisted in situ keratomileusis (LASIK) ectasia (PLE) is traditionally performed either epi-on or epi-off on the corneal surface. This study describes a novel technique in treating early PLE with under-flap CXL (ufCXL) to the stromal bed and reports on 6-month outcomes. PATIENTS AND METHODS: Case series of seven patients (eight eyes) with topography-diagnosed early PLE treated with ufCXL. Inclusion criteria were early, mild PLE defined as new-onset postoperative manifest refraction cylinder ≤1...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27930791/computational-biomechanical-analysis-of-asymmetric-ectasia-risk-in-unilateral-post-lasik-ectasia
#8
Ali Vahdati, Ibrahim Seven, Naveen Mysore, J Bradley Randleman, William J Dupps
PURPOSE: To develop a computational approach to corneal biomechanical risk analysis in refractive surgery and to investigate its utility in an enigmatic case of unilateral ectasia after bilateral LASIK. METHODS: Preoperative corneal elevation datasets from both eyes of a patient who developed unilateral post-LASIK ectasia were used to construct geometrically patient-specific, microstructurally motivated finite element models. Models were assessed before and after implementation of case-specific treatment parameters for interocular differences in corneal geometry and strain behavior under physiological loading conditions...
December 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27824384/refractive-lenticule-transplantation-for-correction-of-iatrogenic-hyperopia-and-high-astigmatism-after-lasik
#9
Apostolos Lazaridis, Dan Z Reinstein, Timothy J Archer, Stephan Schulze, Walter Sekundo
PURPOSE: To design a technique for intrastromal transplantation of stromal lenticules with specific refractive power for correction of post-LASIK induced hyperopia and astigmatism. METHODS: A 28-year-old patient was referred for consultation after complicated LASIK for moderate myopia and astigmatism. The refractive error of the right eye was severely overcorrected due to data entry error. Post-LASIK refraction showed high astigmatism (right eye: +6.50 -9.00 @ 84°) and corrected distance visual acuity (CDVA) of 20/32...
November 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27757009/corneal-endothelial-changes-after-accelerated-corneal-collagen-cross-linking-in-keratoconus-and-postlasik-ectasia
#10
Amani E Badawi
PURPOSE: The purpose of this study was to evaluate the effects of accelerated cross-linking (CXL) on corneal endothelium in keratoconus and postlaser-assisted in situ keratomileusis (LASIK) ectasia. DESIGN: This study is a prospective nonrandomized controlled study. SETTING: This study was conducted in Mansoura Ophthalmic Center (Mansoura University) and Al-Mostakbal Ophthalmic Center, Mansoura, Egypt. METHODS: In total, 40 eyes with progressive keratoconus and 10 eyes with postLASIK ectasia were subjected to an accelerated CXL (10 mW/cm(2) for 9 minutes)...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27689082/efficacy-and-safety-of-lasik-combined-with-accelerated-corneal-collagen-cross-linking-for-myopia-six-month-study
#11
Ying Wu, Lei Tian, Li-Qiang Wang, Yi-Fei Huang
This was a prospective controlled clinical trial. 48 myopia patients (96 eyes) were included in this study. After LASIK, accelerated corneal collagen cross-linking (ACXL) was used for myopia treatment. During 6-month follow-up, the results of LASIK-ACXL treatment were studied and compared to the LASIK-only procedure. The results showed that no statistically significant differences in UDVA, CDVA, MRSE, K mean, pachymetry, or ECD were found between the two groups at the visit after 6 months of follow-up (all P > 0...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27630372/a-large-scale-computational-analysis-of-corneal-structural-response-and-ectasia-risk-in-myopic-laser-refractive-surgery
#12
William Joseph Dupps, Ibrahim Seven
PURPOSE: To investigate biomechanical strain as a structural susceptibility metric for corneal ectasia in a large-scale computational trial. METHODS: A finite element modeling study was performed using retrospective Scheimpflug tomography data from 40 eyes of 40 patients. LASIK and PRK were simulated with varied myopic ablation profiles and flap thickness parameters across eyes from LASIK candidates, patients disqualified for LASIK, subjects with atypical topography, and keratoconus subjects in 280 simulations...
August 2016: Transactions of the American Ophthalmological Society
https://www.readbyqxmd.com/read/27505311/combining-placido-and-corneal-wavefront-data-for-the-detection-of-forme-fruste-keratoconus
#13
Alain Saad, Damien Gatinel
PURPOSE: To evaluate the accuracy of a new objective method based on Placido disk-derived data for the detection of eyes at risk of ectasia. METHODS: One hundred nineteen eyes of 176 patients were included and separated into two groups, normal and forme fruste keratoconus (FFKC), using automated corneal classification software. Normal eyes (n = 114) were classified as negative for keratoconus and keratoconus suspect and had undergone LASIK with unremarkable follow-up for 4 years...
August 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27498450/the-assessment-of-the-stability-of-the-corneal-structure-after-lasik-correction-of-myopia-by-different-optical-zone-diameters
#14
Milorad Milivojević, Vladimir Petrović, Miroslav Vukosavljević, Ivan Marjanović, Mirko Resan
BACKGROUND/AIM: Enlargement of optical zone (OZ) diameter during laser in situ keratomileusis (LASIK) correction of myopia postoperatively improves the optical outcome, however, it also leads to the increased stroma tissue consumption--progressive corneal thinning. The aim of this investigation was to present the possibility of safe OZ enlargement without impairing the structural stability of the cornea, while obtaining an improved optical outcome with LASIK treatment of short-sightedness...
June 2016: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
https://www.readbyqxmd.com/read/27467046/globe-rupture-of-a-post-lasik-keratectasia-eye-from-blunt-trauma
#15
Albert Y Cheung, David G Heidemann
PURPOSE: To report a case of globe rupture in a patient with post-laser in situ keratomileusis (LASIK) ectasia after blunt trauma. METHODS: Observational case report. RESULTS: A 42-year-old man with a history of post-LASIK ectasia sustained paracentral corneal rupture secondary to blunt trauma from a fist to his left eye (OS). Slit-lamp examination revealed rupture in the posterior stroma (inferior paracentral) of the OS with an overlying intact LASIK flap; however, the inferior edges of the LASIK flap were Seidel positive...
December 2016: Cornea
https://www.readbyqxmd.com/read/27466722/prosthetic-replacement-of-the-ocular-surface-ecosystem-prose-treatment-for-complications-after-lasik
#16
Sophia Z Mian, Joshua S Agranat, Deborah S Jacobs
OBJECTIVES: To report experience with Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) treatment for complications after laser in situ keratomileuisis (LASIK). METHODS: Retrospective review of clinical and manufacturing records. A database of patients who underwent PROSE treatment from 1992 to 2007 was searched to yield all patients with history of LASIK. Primary indication for PROSE treatment and year of LASIK is reported as well as history of contact lens intolerance and pretreatment and posttreatment best-corrected visual acuity (BCVA)...
November 2016: Eye & Contact Lens
https://www.readbyqxmd.com/read/27391537/topographic-tomographic-and-aberrometric-characteristics-of-post-lasik-ectasia
#17
Prema Padmanabhan, Sudhir Rachapalle Reddi, Poornima Devi Sivakumar
PURPOSE: To report the refractive, topographic, tomographic, and aberrometric characteristics of post-LASIK ectasia; to compare these characteristics with normal post-LASIK controls; and to propose a comprehensive system to grade the severity of post-LASIK ectasia. METHODS: The refraction, corrected distance visual acuity (CDVA), magnitude, and location of the steepest and thinnest point on the cornea, the highest anterior and posterior surface elevation, the radius of best fit sphere, corneal asphericity, and corneal aberrations were measured in 50 eyes of 29 patients with post-LASIK ectasia...
November 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27315293/-intracorneal-ring-segments-to-treat-keratectasia-interim-results-and-potential-complications
#18
M El-Husseiny, L Daas, A Langenbucher, B Seitz
BACKGROUND AND PURPOSE: Implantation of intracorneal ring segments (ICRS) using a femtosecond laser is a minimally invasive procedure which represents a reliable option to widen the spectrum of the stage-related therapy of keratoconus in patients with contact lens intolerance, or with post-LASIK-keratectasia or pellucide marginale degeneration (PMD). METHODS: From August 2011 to September 2015, 84 eyes of 69 patients were implanted with ICRS. 74 eyes were implanted with INTACS-SK (Intacs, Addition Technology, Inc...
June 2016: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/27255248/sixteen-year-follow-up-of-hyperopic-laser%C3%A2-in-situ-keratomileusis
#19
Reena Dave, David P S O'Brart, Vijay K Wagh, Wei S Lim, Parul Patel, Jennifer Lee, John Marshall
PURPOSE: To assess the long-term efficacy and safety of hyperopic laser in situ keratomileusis (LASIK). SETTING: Department of Ophthalmology, St. Thomas' Hospital, London, United Kingdom. DESIGN: Prospective cohort study. METHODS: Hyperopic LASIK was performed using a mechanical microkeratome, an optical zone of 6.5 mm, and a blend zone of 1.5 mm. Simple hyperopia was treated. RESULTS: The mean patient age was 51...
May 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27152484/combined-laser-in-situ-keratomileusis-and-accelerated-corneal-cross-linking-an-update
#20
REVIEW
Minoru Tomita
PURPOSE OF REVIEW: The purpose is to review the literature of combined laser in-situ keratomileusis (LASIK) and accelerated corneal collagen cross-linking (CXL) in context of its indications-contraindications, kerato-refractive, visual and safety outcomes, particularly with reference to preventing the development of post-LASIK ectasia. RECENT FINDINGS: LASIK + accelerated CXL has been developed with the rationale that the addition of CXL after LASIK may strengthen the LASIK compromised corneal biomechanics and minimize the complications such as post-LASIK ectasia...
July 2016: Current Opinion in Ophthalmology
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