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https://www.readbyqxmd.com/read/28743498/hydrogen-rich-medium-protects-mouse-embryonic-fibroblasts-from-oxidative-stress-by-activating-lkb1-ampk-foxo1-signal-pathway
#1
Jihyun Lee, Goowon Yang, Young-Joo Kim, Tran Quynh Hoa, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha
Persistent oxidative stress is recognized as a major cause of many pathological conditions as well as ageing. However, most clinical trials of dietary antioxidants have failed to produce successful outcomes in treating oxidative stress-induced diseases. Molecular hydrogen (H2) has recently received considerable attention as a therapeutic agent owing to its novel antioxidant properties, a selective scavenger of hydroxyl and peroxynitrite radicals. Beyond this, numerous reports support that H2 can modulate the activity of various cellular signal pathways...
July 22, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28739411/impact-of-heat-moisture-and-annealing-treatments-on-physicochemical-properties-and-digestibility-of-starches-from-different-colored-sweet-potato-varieties
#2
Phan Thanh Bao Trung, Luu Bui Bao Ngoc, Phan Ngoc Hoa, Nguyen Ngoc Thanh Tien, Pham Van Hung
The objective of this study is to investigate the change in physicochemical properties and digestibility of starches isolated from colored sweet potato varieties under heat-moisture treatment (HMT) or annealing treatment (ANN). The results showed that morphology and X-ray diffraction patterns of the sweet potato starches remained unchanged after the HMT or ANN. The HMT significantly reduced peak viscosity, breakdown and setback and significantly increased pasting temperature, trough and final viscosities of the sweet potato starches...
July 21, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28736660/effect-of-higher-order-aberrations-and-intraocular-scatter-on-contrast-sensitivity-measured-with-a-single-instrument
#3
Junlei Zhao, Fei Xiao, Haoxin Zhao, Yun Dai, Yudong Zhang
Higher-order aberrations (HOAs) and intraocular scatter lead to the degradation of image quality on the retina, and consequently deteriorate subjective visual performance. In this article, we modified an adaptive optics double-pass system to combine objective and subjective visual testing capabilities. Employing the modified DP system, we investigated the effects of HOAs and intraocular scatter on contrast sensitivity. Contrast sensitivity measurements were performed with HOAs either retained or corrected by adaptive optics, and with scatter either remaining at the natural eye-induced level or further enhanced by a set of three different scatter filters...
April 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28728368/assessment-of-frozen-storage-duration-effect-on-quality-characteristics-of-various-horsemeat-muscles
#4
Pil Nam Seong, Hyun Woo Seo, Jin Hyoung Kim, Soo Hyun Cho, Yoon Seok Kim, Beom Young Park, Hoa Van Ba
Objective: The study aimed at assessing the effects of frozen storage duration on quality characteristics, lipid oxidation and sensory quality of various horse muscles. Methods: Five representative muscles: longissimus dorsi (LD), gluteus medius (GM), semimembranosus (SM), biceps femoris (BF) and triceps brachii (TB) at 24 h post-mortem obtained from 28-mo-old Jeju female breed horses (n=8) were used in the present investigation. The muscles were vacuum-packaged and frozen at -20oC for 120, 240 and 360 days...
June 27, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28720940/recovery-of-protein-hydrolysate-and-chitosan-from-black-tiger-shrimp-penaeus-monodon-heads-approaching-a-zero-waste-process
#5
Pham Thi Dan Phuong, Nguyen Cong Minh, Hoang Ngoc Cuong, Nguyen Van Minh, Nguyen The Han, Nguyen Van Hoa, Ha Thi Hai Yen, Trang Si Trung
Shrimp heads are considered as a potential source for the recovery of many valuable components such as chitin, protein and carotenoids. In the present study, both protein hydrolysate and chitin/chitosan were recovered using combination of physical, biological and chemical treatments. Shrimp heads were separated from liquid phase by a facile and efficient physical pretreatment. The liquid fraction was then hydrolyzed using formic acid and vacuum concentrated to obtain an astaxanthin-rich protein hydrolysate...
June 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28702217/erratum-to-culturally-adaptive-storytelling-intervention-versus-didactic-intervention-to-improve-hypertension-control-in-vietnam-a-cluster-randomized-controlled-feasibility-trial
#6
Hoa L Nguyen, Jeroan J Allison, Duc A Ha, Germán Chiriboga, Ha N Ly, Hanh T Tran, Cuong K Nguyen, Diem M Dang, Ngoc T Phan, Nguyen C Vu, Quang P Nguyen, Robert J Goldberg
[This corrects the article DOI: 10.1186/s40814-017-0136-9.].
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28701159/bacterial-bloodstream-infections-in-a-tertiary-infectious-diseases-hospital-in-northern-vietnam-aetiology-drug-resistance-and-treatment-outcome
#7
Vu Quoc Dat, Hieu Ngoc Vu, Hung Nguyen The, Hoa Thi Nguyen, Long Bao Hoang, Dung Vu Tien Viet, Chi Linh Bui, Kinh Van Nguyen, Trung Vu Nguyen, Dao Tuyet Trinh, Alessandro Torre, H Rogier van Doorn, Behzad Nadjm, Heiman F L Wertheim
BACKGROUND: Bloodstream infections (BSIs) are associated with high morbidity and mortality worldwide. However their aetiology, antimicrobial susceptibilities and associated outcomes differ between developed and developing countries. Systematic data from Vietnam are scarce. Here we present aetiologic data on BSI in adults admitted to a large tertiary referral hospital for infectious diseases in Hanoi, Vietnam. METHODS: A retrospective study was conducted at the National Hospital for Tropical Diseases between January 2011 and December 2013...
July 12, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28685418/dysfunctional-lens-syndrome
#8
Mohammad Reza Sedaghat, Hamed Momeni-Moghaddam, Shehzad S Naroo, Hossein Ghavamsaeedi, Alireza Vahedi
PURPOSE: To report the pre- and post-operative findings of a case with dysfunctional lens syndrome. METHODS: An adult patient was evaluated using iTrace aberrometer, Tomey topographer and slitlamp biomicroscopy to confirm dysfunctional lens syndrome. RESULTS: A 45-year-old male patient presented with the chief complaint of poor visual quality; uncorrected visual acuity 20/40 in the right eye, best spectacle corrected visual acuity 20/25 in the right eye with refraction Plano/-1...
July 6, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28683793/comparison-of-visual-results-and-higher-order-aberrations-after-small-incision-lenticule-extraction-smile-high-myopia-vs-mild-to-moderate-myopia
#9
Hong-Ying Jin, Ting Wan, Fang Wu, Ke Yao
BACKGROUND: To compare the refractive results and higher-order aberrations (HOAs) after small incision lenticule extraction (SMILE) in high myopia and mild to moderate myopia patients. METHODS: This prospective study included 165 eyes (86 patients) undergoing SMILE. According to the preoperative spherical equivalent (SE), treated eyes were divided into two groups: the high myopia group (more than -6.0 D, group-H) and the mild to moderate group (less than -6.0 D, group-M)...
July 6, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28681909/medium-to-long-term-results-of-corneal-cross-linking-for-keratoconus-using-phototherapeutic-keratectomy-for-epithelial-removal-and-partial-stromal-ablation
#10
Xiangjun Chen, Aleksandar Stojanovic, Yangyang Xu, Wen Zhou, Sten Raeder, Sam Enayati, Tor Paaske Utheim
PURPOSE: To evaluate the medium- to long-term outcomes of corneal cross-linking in treatment of keratoconus using transepithelial phototherapeutic keratectomy (PTK-CXL) for epithelial removal and partial stromal ablation to stabilize the cornea, reduce corneal irregularity, and improve corrected vision. METHODS: Retrospective analysis of 46 keratoconic eyes that underwent PTK-CXL. Corrected distance visual acuity (CDVA), manifest refraction, steep and flat simulated keratometry (Kmax and Kmin), corneal irregularity index (IRI), corneal higher order aberrations (HOAs), epithelial thickness profile, and corneal biomechanical characteristics were evaluated preoperatively and postoperatively...
July 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28681436/human-eyes-do-not-need-monochromatic-aberrations-for-dynamic-accommodation
#11
Paula Bernal-Molina, Iván Marín-Franch, Antonio J Del Águila-Carrasco, Jose J Esteve-Taboada, Norberto López-Gil, Philip B Kruger, Robert Montés-Micó
PURPOSE: To determine if human accommodation uses the eye's own monochromatic aberrations to track dynamic accommodative stimuli. METHODS: Wavefront aberrations were measured while subjects monocularly viewed a monochromatic Maltese cross moving sinusoidally around 2D of accommodative demand with 1D amplitude at 0.2 Hz. The amplitude and phase (delay) of the accommodation response were compared to the actual vergence of the stimulus to obtain gain and temporal phase, calculated from wavefront aberrations recorded over time during experimental trials...
July 5, 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28674018/high-serum-serotonin-in-sudden-infant-death-syndrome
#12
Robin L Haynes, Andrew L Frelinger, Emma K Giles, Richard D Goldstein, Hoa Tran, Harry P Kozakewich, Elisabeth A Haas, Anja J Gerrits, Othon J Mena, Felicia L Trachtenberg, David S Paterson, Gerard T Berry, Khosrow Adeli, Hannah C Kinney, Alan D Michelson
Sudden infant death syndrome (SIDS), the leading cause of postneonatal infant mortality, likely comprises heterogeneous disorders with the common phenotype of sudden death without explanation upon postmortem investigation. Previously, we reported that ∼40% of SIDS deaths are associated with abnormalities in serotonin (5-hydroxytryptamine, 5-HT) in regions of the brainstem critical in homeostatic regulation. Here we tested the hypothesis that SIDS is associated with an alteration in serum 5-HT levels. Serum 5-HT, adjusted for postconceptional age, was significantly elevated (95%) in SIDS infants (n = 61) compared with autopsied controls (n = 15) [SIDS, 177...
July 18, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28673750/quality-of-vision-in-eyes-with-epiphora-undergoing-lacrimal-passage-intubation
#13
Shizuka Koh, Yasushi Inoue, Shintaro Ochi, Yoshihiro Takai, Naoyuki Maeda, Kohji Nishida
PURPOSE: To investigate visual function and optical quality in eyes with epiphora undergoing lacrimal passage intubation. DESIGN: Prospective case series. METHODS: Thirty-four eyes of 30 patients with lacrimal passage obstruction were enrolled. Before and 1 month after lacrimal passage intubation, functional visual acuity (FVA), higher-order aberrations (HOAs), lower tear meniscus and tear clearance were assessed. An FVA measurement system was used to examine changes in continuous visual acuity (VA) over time, and visual function parameters such as FVA, visual maintenance ratio, and blink frequency were obtained...
June 30, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28671724/tunneling-photocurrent-assisted-by-interlayer-excitons-in-staggered-van-der-waals-hetero-bilayers
#14
Dinh Hoa Luong, Hyun Seok Lee, Guru Prakash Neupane, Shrawan Roy, Ganesh Ghimire, Jin Hee Lee, Quoc An Vu, Young Hee Lee
Vertically stacked van der Waals (vdW) heterostructures have been suggested as a robust platform for studying interfacial phenomena and related electric/optoelectronic devices. While the interlayer Coulomb interaction mediated by the vdW coupling has been extensively studied for carrier recombination processes in a diode transport, its correlation with the interlayer tunneling transport has not been elucidated. Here, a contrast is reported between tunneling and drift photocurrents tailored by the interlayer coupling strength in MoSe2 /MoS2 hetero-bilayers (HBs)...
July 3, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28671035/molecular-characterization-of-%C3%AE-thalassemia-mutations-in-central-vietnam
#15
Maria G Doro, Giuseppina Casu, Laura Frogheri, Ivana Persico, Le Phan Minh Triet, Phan Thi Thuy Hoa, Nguyen Huy Hoang, Monica Pirastru, Paolo Mereu, Francesco Cucca, Bruno Masala
The molecular basis of β-thalassemia (β-thal) mutations in North and in South Vietnam have been described during the past 15 years, whereas limited data were available concerning the central area of the country. In this study, we describe the molecular characterization and frequency of β-globin gene mutations in the Thua Thien Hue Province of Central Vietnam as the result of a first survey conducted in 22 transfusion-dependent patients, and four unrelated heterozygotes. Nine different known mutations were identified (seven of the β(0) and two of the β(+) type) in a total of 48 chromosomes...
March 2017: Hemoglobin
https://www.readbyqxmd.com/read/28667961/novel-design-of-high-voltage-pulse-source-for-efficient-dielectric-barrier-discharge-generation-by-using-silicon-diodes-for-alternating-current
#16
Hoa Thi Truong, Misaki Hayashi, Yoshihiko Uesugi, Yasunori Tanaka, Tatsuo Ishijima
This work focuses on design, construction, and optimization of configuration of a novel high voltage pulse power source for large-scale dielectric barrier discharge (DBD) generation. The pulses were generated by using the high-speed switching characteristic of an inexpensive device called silicon diodes for alternating current and the self-terminated characteristic of DBD. The operation started to be powered by a primary DC low voltage power supply flexibly equipped with a commercial DC power supply, or a battery, or DC output of an independent photovoltaic system without transformer employment...
June 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28665538/%C3%AE-glucosidase-inhibitory-xanthones-from-the-roots-of-garcinia-fusca
#17
Nam K Nguyen, Xuyen A Truong, Thai Q Bui, Dzung N Bui, Hai X Nguyen, Phuong T Tran, Lien-Hoa D Nguyen
An ethyl acetate extract of the roots of Garcinia fusca produced two new compounds, fuscaxanthones J (1) and K (2), together with eight known xanthones (3-10). Their structures were determined using spectroscopic methods, mainly 1-D and 2-D NMR. α-Glucosidase inhibitory activity of the isolated compounds was evaluated and fuscaxanthone J (1) showed the most significant effect with IC50 value of 8.3 ± 1.8 μM (compared with acarbose, IC50 = 214.5 ± 2.3 μM). This article is protected by copyright. All rights reserved...
June 30, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28662727/frontal-brain-activation-changes-due-to-dual-tasking-under-partial-body-weight-support-conditions-in-older-adults-with-multiple-sclerosis
#18
Gioella Chaparro, Julia M Balto, Brian M Sandroff, Roee Holtzer, Meltem Izzetoglu, Robert W Motl, Manuel E Hernandez
BACKGROUND: Gait impairments present while dual-tasking in older adults with multiple sclerosis (MS) have been associated with an increased risk of falls. Prior studies have examined prefrontal cortex (PFC) activity using functional near infrared spectroscopy (fNIRS) while dual-tasking in older adults with and without cognitive impairment. While the benefits of partial body weight support (PBWS) on gait have been clearly outlined in the literature, the potential use of PBWS to improve the ability to dual task in older adults with and without MS has not been examined...
June 29, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28661465/antibiotic-resistance-and-antibiotic-resistance-genes-in-escherichia-coli-isolates-from-hospital-wastewater-in-vietnam
#19
La Thi Quynh Lien, Pham Thi Lan, Nguyen Thi Kim Chuc, Nguyen Quynh Hoa, Pham Hong Nhung, Nguyen Thi Minh Thoa, Vishal Diwan, Ashok J Tamhankar, Cecilia Stålsby Lundborg
The environmental spread of antibiotic-resistant bacteria has been recognised as a growing public health threat for which hospitals play a significant role. The aims of this study were to investigate the prevalence of antibiotic resistance and antibiotic resistance genes (ARGs) in Escherichia coli isolates from hospital wastewater in Vietnam. Wastewater samples before and after treatment were collected using continuous sampling every month over a year. Standard disk diffusion and E-test were used for antibiotic susceptibility testing...
June 29, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28661450/functional-amyloids-in-reproduction
#20
REVIEW
Aveline Hewetson, Hoa Quynh Do, Caitlyn Myers, Archana Muthusubramanian, Roger Bryan Sutton, Benjamin J Wylie, Gail A Cornwall
Amyloids are traditionally considered pathological protein aggregates that play causative roles in neurodegenerative disease, diabetes and prionopathies. However, increasing evidence indicates that in many biological systems nonpathological amyloids are formed for functional purposes. In this review, we will specifically describe amyloids that carry out biological roles in sexual reproduction including the processes of gametogenesis, germline specification, sperm maturation and fertilization. Several of these functional amyloids are evolutionarily conserved across several taxa, including human, emphasizing the critical role amyloids perform in reproduction...
June 29, 2017: Biomolecules
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