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https://www.readbyqxmd.com/read/28317678/quality-of-vision-after-wavefront-guided-laser-in-situ-keratomileusis-or-photorefractive-keratectomy-contralateral-eye-evaluation
#1
Michele D Lee, Edward E Manche
PURPOSE: To compare quality of vision between laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK). SETTING: Byers Eye Institute, Stanford University School of Medicine, Palo Alto, California, USA. DESIGN: Prospective randomized case series. METHODS: Patients had refractive surgery, with 1 eye treated with LASIK and the other with PRK. Eyes were randomized for dominance. The patients completed a questionnaire assessing quality of vision in each eye at the initial visit and 1, 3, 6, and 12 months postoperatively...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28303903/a-novel-toolbox-to-investigate-tissue-spatial-organization-applied-to-the-study-of-the-islets-of-langerhans
#2
Hoa Tran Thi Nhu, Rafael Arrojo E Drigo, Per-Olof Berggren, Thomas Boudier
Thanks to the development of new 3D Imaging techniques, volumetric data of thick samples, especially tissues, are commonly available. Several algorithms were proposed to analyze cells or nuclei in tissues, however these tools are limited to two dimensions. Within any given tissue, cells are not likely to be organized randomly and as such have specific patterns of cell-cell interaction forming complex communication networks. In this paper, we propose a new set of tools as an approach to segment and analyze tissues in 3D with single cell resolution...
March 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28303384/spinopelvic-parameter-changes-and-low-back-pain-improvement-due-to-femoral-neck-anteversion-in-patients-with-severe-unilateral-primary-hip-osteoarthritis-undergoing-total-hip-replacement
#3
Andrea Piazzolla, Giuseppe Solarino, Davide Bizzoca, Viola Montemurro, Pedro Berjano, Claudio Lamartina, Biagio Moretti
PURPOSE: The study of the interrelation between hip and spine disorders is gaining increasing importance in the last years, but the link between Hip Osteoarthritis (HOA) and Low Back Pain (LBP) remains still unclear. Aim of the study is to assess the relationship between Femoral Neck Anteversion (FNA), LBP, and spinopelvic parameters in patients undergoing Total Hip Replacement (THR) for unilateral severe primary HOA. MATERIALS AND METHODS: 91 patients were recruited...
March 16, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28295602/child-survival-revolutions-revisited-lessons-learned-from-bangladesh-nicaragua-rwanda-and-vietnam
#4
REVIEW
Lars Åke Persson, Anisur Rahman, Rodolfo Peña, Wilton Perez, Aimable Musafili, Dinh Phuong Hoa
Analysing child mortality may enhance our perspective on global achievements in child survival. We used data from surveillance sites in Bangladesh, Nicaragua and Vietnam and Demographic Health Surveys in Rwanda to explore the development of neonatal and under-five mortality. The mortality curves showed dramatic reductions over time, but child mortality in the four countries peaked during wars and catastrophes and was rapidly reduced by targeted interventions, multi-sectorial development efforts and community engagement CONCLUSION: Lessons learned from these countries may be useful when tackling future challenges, including persistent neonatal deaths, survival inequalities and the consequences of climate change and migration...
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28295383/recovery-of-pectic-hydrocolloids-and-phenolics-from-huanglongbing-related-dropped-citrus-fruit
#5
Randall G Cameron, Hoa K Chau, Arland T Hotchkiss, John A Manthey
BACKGROUND: Citrus preharvest fruit drop, caused by Huanglongbing infection, has increased dramatically concomitant with declining tree health and crop harvest size. This loss of harvestable fruit is damaging to both growers and juice processors. Recovering and converting this fruit to alternative value added products would benefit the citrus industry. Therefore, we have explored the potential for using this fruit as a feedstock in our newly developed pilot scale continuous steam explosion process...
March 12, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28292680/robust-quantitation-of-basic-protein-higher-order-aggregates-using-size-exclusion-chromatography
#6
David Gervais, Andrew Downer, Darryl King, Patrick Kanda, Nicholas Foote, Stuart Smith
Detection of higher-order aggregates (HOA) using size-exclusion chromatography (SEC) was found to be variable for a basic protein, using exposed-silanol or diol-silica-based SEC columns. Preparations of the tetrameric biopharmaceutical enzyme Erwinia chrysanthemil-asparaginase (ErA), which has an isoelectric point of 8.6, were analysed using a diol-silica SEC column. Although the proportions of ErA main peak and octamer species were unaffected, HOA recovery and detection were extremely variable and had poor agreement with an orthogonal measurement technique, analytical ultracentrifugation (AUC)...
March 7, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28290736/accuracy-and-reliability-of-marker-based-approaches-to-scale-the-pelvis-thigh-and-shank-segments-in-musculoskeletal-models
#7
Hans Kainz, Hoa Hoang, Chris Stockton, Roslyn R Boyd, David G Lloyd, Christopher P Carty
Gait analysis together with musculoskeletal modelling is widely used for research. In the absence of medical images, surface marker locations are used to scale a generic model to the individual's anthropometry. Studies evaluating the accuracy and reliability of different scaling approaches in a paediatric and/or clinical population have not yet been conducted and, therefore, formed the aim of this study. Magnetic resonance images (MRI) and motion capture data were collected from twelve participants with cerebral palsy and six typically developed participants...
March 14, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28290280/combined-effect-of-shearing-and-cooling-rate-on-the-rheology-of-organogels-developed-by-selected-gelators
#8
A De la Peña-Gil, F M Álvarez-Mitre, M M González-Chávez, M A Charó-Alonso, J F Toro-Vazquez
In this study we investigated the combined effect of shearing and cooling rate in the rheology of organogels developed in high oleic safflower oil by (R)-12-hydroxystearic acid (HSA), its primary amide derivative [(R)-12-hydroxyoctadecanamide, HOA], and the N-octadecyl derivative of HOA [(R)-N-octadecyl-12-hydroxyoctadecanamide, OHOA]. The experimental set up to develop the organogels involved: 1). The use of quiescent (0s(-1)) or shearing (300, 600, and 1200s(-1)) conditions during cooling the gelator solutions (2%) just until achieving the gelator's melting temperature (TM) in the vegetable oil, to then continuing the cooling under static conditions until achieving 15°C) The use of cooling rate protocols involving a constant cooling rate of 1°C/min (CR1) or 10°C/min (CR10) in the shearing and static stages, or variable cooling rates in each stage (i...
March 2017: Food Research International
https://www.readbyqxmd.com/read/28285388/effect-of-iris-registration-on-visual-outcome-in-wavefront-guided-lasek-for-myopic-astigmatism
#9
Jong Joo Lee, Mee Kum Kim, Won Ryang Wee
PURPOSE: This study aimed to investigate the effect of iris registration (IR) on visual outcomes in wavefront-guided LASEK for myopic astigmatism. METHODS: The retrospective chart review was performed for wavefront-guided LASEK using VISX Star S4 in patients with myopic astigmatism (cylinder ≥ 1.00 diopter[D]). Eyes were divided into IR group (LASEK with IR at the time of surgery) and Non-IR group (LASEK without IR system + failed-IR engagement during LASEK)...
March 11, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28274429/pectic-oligosaccharide-structure-function-relationships-prebiotics-inhibitors-of-escherichia-coli-o157-h7-adhesion-and-reduction-of-shiga-toxin-cytotoxicity-in-ht29-cells
#10
Rong Di, Malathi S Vakkalanka, Chatchaya Onumpai, Hoa K Chau, Andre White, Robert A Rastall, Kit Yam, Arland T Hotchkiss
Shiga toxin (Stx)-producing, food-contaminating Escherichia coli (STEC) is a major health concern. Plant-derived pectin and pectic-oligosaccharides (POS) have been considered as prebiotics and for the protection of humans from Stx. Of five structurally different citrus pectic samples, POS1, POS2 and modified citrus pectin 1 (MCP1) were bifidogenic with similar fermentabilities in human faecal cultures and arabinose-rich POS2 had the greatest prebiotic potential. Pectic oligosaccharides also enhanced lactobacilli growth during mixed batch faecal fermentation...
July 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28271543/associations-between-pro-inflammatory-cytokines-learning-and-memory-in-late-life-depression-and-healthy-aging
#11
Rebecca A Charlton, Melissa Lamar, Aifeng Zhang, Xinguo Ren, Olusola Ajilore, Ghanshyam N Pandey, Anand Kumar
OBJECTIVES: Pro-inflammatory cytokines may play a role in learning and memory difficulties and may be exacerbated in late-life depression (LLD), where pro-inflammatory markers are already elevated because of aging and age-related vascular risk. METHODS: Learning and memory, and pro-inflammatory cytokines-Interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and Interleukin-6 (IL-6) were measured in 24 individuals with LLD and 34 healthy older adults (HOA)...
March 8, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28262745/a-biomimetic-gelatin-based-platform-elicits-a-pro-differentiation-effect-on-podocytes-through-mechanotransduction
#12
Mufeng Hu, Evren U Azeloglu, Amit Ron, Khanh-Hoa Tran-Ba, Rhodora C Calizo, Iman Tavassoly, Smiti Bhattacharya, Gomathi Jayaraman, Yibang Chen, Vera Rabinovich, Ravi Iyengar, James C Hone, John C He, Laura J Kaufman
Using a gelatin microbial transglutaminase (gelatin-mTG) cell culture platform tuned to exhibit stiffness spanning that of healthy and diseased glomeruli, we demonstrate that kidney podocytes show marked stiffness sensitivity. Podocyte-specific markers that are critical in the formation of the renal filtration barrier are found to be regulated in association with stiffness-mediated cellular behaviors. While podocytes typically de-differentiate in culture and show diminished physiological function in nephropathies characterized by altered tissue stiffness, we show that gelatin-mTG substrates with Young's modulus near that of healthy glomeruli elicit a pro-differentiation and maturation response in podocytes better than substrates either softer or stiffer...
March 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28254051/chemical-characterization-and-source-apportionment-of-atmospheric-submicron-particles-on-the-western-coast-of-taiwan-strait-china
#13
Liming Cao, Qiao Zhu, Xiaofeng Huang, Junjun Deng, Jinsheng Chen, Youwei Hong, Lingling Xu, Lingyan He
Taiwan Strait is a special channel for subtropical East Asian Monsoon and its western coast is an important economic zone in China. In this study, a suburban site in the city of Xiamen on the western coast of Taiwan Strait was selected for fine aerosol study to improve the understanding of air pollution sources in this region. An Aerodyne high-resolution time-of-flight aerosol mass spectrometer (HR-ToF-AMS) and an Aethalometer were deployed to measure fine aerosol composition with a time resolution of 5 min from May 1 to 18, 2015...
February 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28250191/food-insecurity-is-associated-with-subjective-well-being-among-individuals-from-138-countries-in-the-2014-gallup-world-poll
#14
Edward A Frongillo, Hoa T Nguyen, Michael D Smith, Alisha Coleman-Jensen
Background: Food insecurity is an aspect of living conditions that is particularly important for quality of life, health, and subjective well-being. The implementation of the 8-item Food Insecurity Experience Scale in 147 countries in the 2014 Gallup World Poll provided an unprecedented opportunity to understand the association of food insecurity with subjective well-being.Objective: We examined how food insecurity relates with measures of living conditions and how food insecurity and other living conditions relate with physical health and, in turn, subjective well-being...
March 1, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28243467/coronary-heart-disease-is-associated-with-a-worse-clinical-outcome-of-hand-osteoarthritis-a-cross-sectional-and-longitudinal-study
#15
Alice Courties, Jérémie Sellam, Emmanuel Maheu, Christian Cadet, Yoann Barthe, Fabrice Carrat, Francis Berenbaum
OBJECTIVE: To determine whether cardiometabolic factors are associated with hand osteoarthritis (HOA) symptoms, radiographic severity and progression in a post hoc analysis of the phase III Strontium ranelate Efficacy in Knee OsteoarthrItis triAl (SEKOIA) trial, designed to determine the effect of strontium ranelate on knee osteoarthritis (OA). METHODS: Among the 1683 patients randomised in the SEKOIA study, 869 with radiographic HOA at baseline (rHOA≥2 joints with Kellgren-Lawrence grade ≥2) were included in a cross-sectional analysis...
2017: RMD Open
https://www.readbyqxmd.com/read/28241225/laryngeal-aerodynamics-in-healthy-older-adults-and-adults-with-parkinson-s-disease
#16
Deborah Matheron, Elaine T Stathopoulos, Jessica E Huber, Joan E Sussman
Purpose: The present study compared laryngeal aerodynamic function of healthy older adults (HOA) to adults with Parkinson's disease (PD) while speaking at a comfortable and increased vocal intensity. Method: Laryngeal aerodynamic measures (subglottal pressure, peak-to-peak flow, minimum flow, and open quotient [OQ]) were compared between HOAs and individuals with PD who had a diagnosis of hypophonia. Increased vocal intensity was elicited via monaurally presented multitalker background noise...
March 1, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28241043/use-of-eschar-swabbing-for-the-molecular-diagnosis-and-genotyping-of-orientia-tsutsugamushi-causing-scrub-typhus-in-quang-nam-province-vietnam
#17
Nhiem Le Viet, Maureen Laroche, Hoa L Thi Pham, Nho L Viet, Oleg Mediannikov, Didier Raoult, Philippe Parola
BACKGROUND: Scrub typhus is a rickettsiosis which is caused by Orientia tsutsugamushi and occurs throughout the Asia-Pacific region. Molecular diagnosis of rickettsioses using eschar swabs has recently emerged, and may be very useful for the diagnosis of these diseases in tropical settings. METHODOLOGY/PRINCIPAL FINDINGS: Quantitative polymerase chain reaction (qPCR) was used to detect O. tsutsugamushi DNA in whole blood and eschar swab specimens of 67 patients who were clinically suspected of scrub typhus in Quang Nam province, Vietnam...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28239301/the-reversal-effect-of-prothrombin-complex-concentrate-pcc-activated-pcc-and-recombinant-activated-factor-vii-against-anticoagulation-of-xa-inhibitor
#18
Nina Haagenrud Schultz, Hoa Thi Tuyet Tran, Stine Bjørnsen, Carola Elisabeth Henriksson, Per Morten Sandset, Pål Andre Holme
BACKGROUND: An increasing number of patients are treated with direct-acting oral anticoagulants (DOACs), but the optimal way to reverse the anticoagulant effect is not known. Specific antidotes are not available and prothrombin complex concentrate (PCC), activated PCC (aPCC) and recombinant factor VIIa (rFVIIa) are variously used as reversal agents in case of a major bleeding. We aimed to determine the most effective haemostatic agent and dose to reverse the effect of rivaroxaban in blood samples from patients taking rivaroxaban for therapeutic reasons...
2017: Thrombosis Journal
https://www.readbyqxmd.com/read/28237233/application-of-discrete-choice-experiment-to-assess-farmers-willingness-to-report-swine-diseases-in-the-red-river-delta-region-vietnam
#19
Hoa T T Pham, Marisa Peyre, Tuyen Quang Trinh, Oanh Cong Nguyen, Ton Dinh Vu, Theera Rukkwamsuk, Nicolas Antoine-Moussiaux
A discrete choice experiment (DCE) is carried out to value socio-economic factors influencing the farmer's decision to report swine diseases and to assess the willingness of farmers to report swine diseases. Data were collected between March and July 2015 in two provinces in the Red River Delta, Northern Vietnam, from 196 pig producers by face-to face interview. A conditional logit model is used to measure the relative importance of the socio-economic factors and calculate the expected probability of disease reporting under changes of levels of these factors...
March 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28225339/latent-tuberculous-infection-in-household-contacts-of-multidrug-resistant-and-newly-diagnosed-tuberculosis
#20
G J Fox, N T Anh, N V Nhung, N T Loi, N B Hoa, L T Ngoc Anh, N K Cuong, T N Buu, G B Marks, D Menzies
BACKGROUND: Differences in the prevalence of latent tuberculous infection (LTBI) and tuberculosis (TB) disease among contacts of patients with multidrug-resistant TB (MDR-TB) and drug-susceptible TB are not well understood. OBJECTIVE: To compare the prevalence of tuberculin skin test (TST) positivity in household contacts of patients with MDR-TB and in contacts of patients never previously treated for TB ('new TB'). DESIGN: Consecutive patients with MDR-TB and their household contacts at nine urban district clinics in Viet Nam were screened for TB and LTBI, and followed up for 6 months...
March 1, 2017: International Journal of Tuberculosis and Lung Disease
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