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https://www.readbyqxmd.com/read/28633712/use-of-inhaled-corticosteroids-for-obstructive-lung-disease-following-anti-tuberculosis-treatment
#1
Anthony D Harries, Serge Ade, Nguyen Binh Hoa, Srinath Satyanarayana, Ajay M V Kumar
No abstract text is available yet for this article.
July 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28626821/mesopic-visual-quality-after-accelerated-corneal-cross-linking-a-12-month-follow-up-study
#2
Hassan Hashemi, Soheila Asgari
PURPOSE: To determine the 1-year changes of mesopic higher order aberrations (HOAs) and contrast sensitivity (CS) after accelerated corneal cross linking (CXL) in progressive keratoconus. METHODS: In this prospective case series, 70 eyes of 62 keratoconic patients underwent accelerated CXL (18 mW/cm(2), 5 min). HOAs and CS were measured using the OPD Scan III and CSV-1000 CS test charts under mesopic conditions before and 6 and 12 months after CXL. RESULTS: At 1 year, logarithmic mesopic CS in spatial frequencies of 3, 6, 12, and 18 cycles per degree (CPD) had increased by 0...
June 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28624142/anti-diabetic-xanthones-from-the-bark-of-garcinia-xanthochymus
#3
Chi N Nguyen, Binh T D Trinh, Toan B Tran, Le-Thu T Nguyen, Anna K Jäger, Lien-Hoa D Nguyen
An ethyl acetate extract the bark of Garcinia xanthochymus exhibited strong inhibition towards α-glucosidase and PTP1B with IC50 values of 0.3±0.1μg/mL and 2.3±0.4μg/mL, respectively. Chemical constituents of the extract were therefore examined, and two new compounds, xanthochymusxanthones A (1) and B (2), along with ten known xanthones (3-12), were isolated. Their structures were determined using spectroscopic methods, mainly 1D and 2D NMR. Inhibitory activity of the isolated compounds was then tested, and subelliptenone F (12) showed significant effect towards α-glucosidase with IC50 value of 4...
June 8, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28623904/impact-of-preconceptional-micronutrient-supplementation-on-maternal-mental-health-during-pregnancy-and-postpartum-results-from-a-randomized-controlled-trial-in-vietnam
#4
Phuong H Nguyen, Ann M DiGirolamo, Ines Gonzalez-Casanova, Hoa Pham, Wei Hao, Hieu Nguyen, Truong V Truong, Son Nguyen, Kimberly B Harding, Gregory A Reinhart, Reynaldo Martorell, Usha Ramakrishnan
BACKGROUND: Micronutrient malnutrition has been associated with maternal depressive symptoms (MDS), but little is known about the effects of preconceptional micronutrient supplementation. This paper examined the effects of preconceptional micronutrient supplementation on MDS during pregnancy and postpartum. METHODS: We used data from a double-blind controlled trial (PRECONCEPT) in which 5011 Vietnamese women were randomized to receive weekly supplements containing either a) multiple micronutrients (MM) b) iron and folic acid (IFA) or c) folic acid (FA) until conception (n = 1813)...
June 17, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28619105/patterns-of-antimicrobial-resistance-in-intensive-care-unit-patients-a-study-in-vietnam
#5
Giang M Tran, Thao P Ho-Le, Duc T Ha, Chau H Tran-Nguyen, Tuyet S M Nguyen, Thao T N Pham, Tuyet A Nguyen, Dung A Nguyen, Hoa Q Hoang, Ngoc V Tran, Tuan V Nguyen
BACKGROUND: Antimicrobial resistance has emerged as a major concern in developing countries. The present study sought to define the pattern of antimicrobial resistance in ICU patients with ventilator-associated pneumonia. METHODS: Between November 2014 and September 2015, we enrolled 220 patients (average age ~ 71 yr) who were admitted to ICU in a major tertiary hospital in Ho Chi Minh City, Vietnam. Data concerning demographic characteristics and clinical history were collected from each patient...
June 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28617099/characterising-omission-errors-in-everyday-task-completion-and-cognitive-correlates-in-individuals-with-mild-cognitive-impairment-and-dementia
#6
Jenna Beaver, Kaci B Wilson, Maureen Schmitter-Edgecombe
OBJECTIVE: Functional ability declines with age and cognitive impairment. This study investigated errors of omission made by community-dwelling older adults completing everyday tasks in a naturalistic setting. METHOD: Sixty-five cognitively healthy older adults (HOA), 19 individuals with single domain mild cognitive impairment (sdMCI), 33 individuals with multi-domain MCI (mdMCI), and 13 individuals with dementia completed measures of memory, processing speed, working memory, and executive functioning, as well as eight different activities of daily living in a naturalistic environment...
June 14, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/28615923/changes-in-meibomian-gland-morphology-and-ocular-higher-order-aberrations-in-eyes-with-chalazion
#7
Shima Fukuoka, Reiko Arita, Rika Shirakawa, Naoyuki Morishige
PURPOSE: To examine the changes in meibomian gland morphology and ocular higher-order aberrations (HOAs) in eyes with chalazion and its excision. METHODS: Seven male patients with previous history of chalazion excision and seven control male subjects were enrolled. Changes in meibomian gland morphology (meiboscores, gland dropout, and shortening) were evaluated by using meibography equipped in a wavefront analyzer KR-1W and in a slit-lamp device BG-4M. Ocular HOAs were measured sequentially with KR-1W...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28611133/long-term-clinical-outcome-of-femtosecond-laser-assisted-lamellar-keratectomy-with-phototherapeutic-keratectomy-in-anterior-corneal-stromal-dystrophy
#8
Jonghyun Lee, Jin Hyoung Kim, Doh Lee, Ji Woong Chang, Joo Youn Shin, Ji Won Seo, Min Hwan Seo, Nam Ju Moon
PURPOSE: To evaluate long-term outcome of femtosecond laser-assisted lamellar keratectomy (FLK) with phototherapeutic keratectomy (PTK) in patients with anterior corneal stromal dystrophies. METHODS: A total of 10 eyes from seven patients who underwent FLK were included. The patients had suffered from recurrent corneal erosion or visual disturbance in anterior corneal dystrophies (five Avellino dystrophies and two lattice dystrophies). Planar-shaped lamellar keratectomy was performed using femtosecond laser...
June 13, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28600494/serum-lipid-levels-and-risk-of-hand-osteoarthritis-the-chingford-prospective-cohort-study
#9
M Garcia-Gil, C Reyes, R Ramos, M T Sanchez-Santos, D Prieto-Alhambra, T D Spector, D J Hart, N K Arden
The development of hand osteoarthritis (HOA) could be linked to hyperlipidaemia. No longitudinal studies have addressed the relationship between serum lipid profile and HOA. The study aim was to determine the association between serum lipid profile and the incidence of radiographic hand osteoarthritis (RHOA). All women in a prospective population-based cohort from the Chingford study with available baseline lipid measurements and without RHOA on a baseline were included. Study outcome was the incidence of RHOA in year 11 of follow-up...
June 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28600472/precision-medicine-in-pediatric-oncology-translating-genomic-discoveries-into-optimized-therapies
#10
Thai Hoa Tran, Avanthi Tayi Shah, Mignon L Loh
Survival of children with cancers has dramatically improved over the past several decades.  This success has been achieved through improvement of combined modalities in treatment approaches, intensification of cytotoxic chemotherapy for those with high-risk disease and refinement of risk stratification incorporating novel biologic markers in addition to traditional clinical and histologic features. Advances in cancer genomics have shed important mechanistic insights on disease biology and have identified "driver" genomic alterations, aberrant activation of signaling pathways, and epigenetic modifiers that can be targeted by novel agents...
June 9, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28594474/cyclopenta-ring-fused-bisanthene-and-its-charged-species-with-open-shell-singlet-diradical-character-and-global-aromaticity-anti-aromaticity
#11
Qing Wang, Tullimilli Y Gopalakrishna, Hoa Phan, Tun Seng Herng, Shaoqiang Dong, Jun Ding, Chunyan Chi
Cyclopenta ring fused bisanthene and its charged species were synthesized. The neutral compound has open-shell singlet ground state and displays global anti-aromaticity. The dication also exhibits singlet diradical character but has a unique [10]annulene-within-[18]annulene global aromatic structure. The dianion is closed-shell singlet in ground state and shows global aromaticity with 22 π-electrons delocalized along the periphery. Our research gave new insight into the design and properties of global aromatic/anti-aromatic systems based on π-conjugated polycyclic hydrocarbons...
June 8, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28592462/ten-year-2001-2011-trends-in-the-incidence-rates-and-short-term-outcomes-of-early-versus-late-onset-cardiogenic-shock-after-hospitalization-for-acute-myocardial-infarction
#12
Hoa L Nguyen, Jorge Yarzebski, Darleen Lessard, Joel M Gore, David D McManus, Robert J Goldberg
BACKGROUND: Cardiogenic shock (CS) is a serious complication of acute myocardial infarction, and the time of onset of CS has a potential role in influencing its prognosis. Limited contemporary data exist on this complication, however, especially from a population-based perspective. Our study objectives were to describe decade-long trends in the incidence, in-hospital mortality, and factors associated with the development of CS in 3 temporal contexts: (1) before hospital arrival for acute myocardial infarction (prehospital CS); (2) within 24 hours of hospitalization (early CS); and (3) ≥24 hours after hospitalization (late CS)...
June 7, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28590792/antibiotic-prescribing-and-dispensing-for-acute-respiratory-infections-in-children-effectiveness-of-a-multi-faceted-intervention-for-health-care-providers-in-vietnam
#13
Nguyen Quynh Hoa, Pham Thi Lan, Ho D Phuc, Nguyen Thi Kim Chuc, Cecilia Stalsby Lundborg
BACKGROUND: Appropriate antibiotic use is vital to effectively contain antibiotic resistance and improve global health. Acute respiratory infections (ARIs) remain the leading cause of disease and death in children under five in low-income countries. OBJECTIVE: To evaluate a multi-faceted intervention targeting health-care-providers' (HCPs) knowledge, practical competences and practices regarding antibiotic use for ARIs. METHODS: A multi-faceted educational intervention with a two-armed randomised controlled design targeting HCPs treating ARIs in children was conducted in Bavi district, a rural district in Northern Vietnam in 2010-2011...
2017: Global Health Action
https://www.readbyqxmd.com/read/28586914/visual-performance-and-optical-quality-of-standardized-asymmetric-soft-contact-lenses-in-patients-with-keratoconus
#14
Asaki Suzaki, Naoyuki Maeda, Mutsumi Fuchihata, Shizuka Koh, Kohji Nishida, Takashi Fujikado
Purpose: To evaluate the visual performance and optical quality of a standardized asymmetric soft contact lens (SCL) used for correction of higher-order aberrations (HOAs) in eyes with keratoconus. Methods: We included 30 eyes (26 patients) with keratoconus (average K: 45.7 ± 2.3 diopters [D]). The patients were subjected to corneal tomography, aberrometry, measurements of manifest refraction and visual acuity (VA), and visual analog scale (VAS) assessments. The study lenses were made using a molding method and consisted of six standardized types, in which an asymmetric power distribution of approximately 2 to 12 D (2-D step) was used to correct HOAs...
June 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28578676/effects-of-optical-diameter-of-intraocular-lenses-with-intrascleral-fixation-on-higher-order-aberrations
#15
Daisuke Kunita, Makoto Inoue, Yuji Itoh, Naoko Matsuki, Toshiyuki Nagamoto, Akito Hirakata
BACKGROUND: Intrascleral fixation of an intraocular lens (IOL) is used in eyes that lack capsular support. The aim of the study is to determine whether a larger optical diameter IOL will decrease the higher-order aberrations (HOAs) when the haptics are extended for intrascleral fixation than a smaller diameter IOL. METHODS: Three-piece acrylic IOLs with 6.0 mm optics (X-60, VA-60BBR) and 7.0 mm optics (X-70, VA-70 AD) were fixed at lengths of 13, 14, 15, 16, or 17 mm...
June 2, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28576067/ph-triggered-degradable-polymeric-micelles-for-targeted-anti-tumor-drug-delivery
#16
Lipeng Qiu, Mengqin Zhu, Kai Gong, Huanhuan Peng, Lu Ge, Li Zhao, Jinghua Chen
2-(Octadecyloxy)-1,3-dioxan-5-amine (OD) with an acid degradable ortho ester group was synthesized, and conjugated to hyaluronic acid (HA) backbone to prepare pH-responsive and tumor-targeted hyaluronic acid-2-(octadecyloxy)-1,3-dioxan-5-amine (HOD) conjugates. (1)H NMR was used to confirm the structures of the OD and HOD. The studies of pH-responsive behavior showed that HOD micelles were stable under physiological conditions while they were degraded in the tumor acidic microenvironment. Doxorubicin (DOX)-loaded HOD micelles (DOX/HOD) with a narrow size distribution were prepared and characterized...
September 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28574579/the-effect-of-a-maternal-history-of-childhood-abuse-on-adrenocortical-attunement-in-mothers-and-their-toddlers
#17
Anna Fuchs, Eva Moehler, Franz Resch, Michael Kaess
We investigated circadian mother-child adrenocortical attunement in the context of a maternal history of childhood abuse (HoA). Mothers were screened after birth using the Childhood Trauma Questionnaire. Women reporting moderate or severe abuse formed the HoA group (n = 37; HoAG) and were compared with a non-maltreated comparison group (n = 45; CG). Three years later, cortisol awakening response (CAR) and diurnal slope (DSL) were assessed. Mother-child interaction was coded using the Emotional Availability Scales at 12 months of age...
June 2, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/28571575/active-case-finding-for-tuberculosis-by-mobile-teams-in-myanmar-yield-and-treatment-outcomes
#18
Ohnmar Myint, Saw Saw, Petros Isaakidis, Mohammed Khogali, Anthony Reid, Nguyen Binh Hoa, Thi Thi Kyaw, Ko Ko Zaw, Tin Mi Mi Khaing, Si Thu Aung
BACKGROUND: Since 2005, the Myanmar National Tuberculosis Programme (NTP) has been implementing active case finding (ACF) activities involving mobile teams in hard-to-reach areas. This study revealed the contribution of mobile team activities to total tuberculosis (TB) case detection, characteristics of TB patients detected by mobile teams and their treatment outcomes. METHODS: This was a descriptive study using routine programme data between October 2014 and December 2014...
June 2, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28560828/toward-benzobis-thiadiazole-based-diradicaloids
#19
Jishan Wu, Yi Liu, Hoa Phan, Tun Seng Herng, Tullimilli Y Gopalakrishna, Jun Ding
We theoretically predicted that acetylene-bridged benzo[1,2-c;4,5-c']bis[1,2,5]thiadiazole (BBT) oligomers would show a quick increase of diradical character with extension of chain length. To validate the hypothesis, six stable BBT-based diradicaloids were synthesized and fully characterized by X-ray crystallographic analysis and various spectroscopic measurements. Three of them showed prominent paramagnetic activity at elevated temperatures due to thermal population from the open-shell singlet ground state to triplet excited state...
May 30, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28559463/development-and-testing-of-a-bubble-bi-level-positive-airway-pressure-system
#20
Stephen C John, Joseph D Barnett, Nickolas D Habben, Hoa T Le, Eric Cheng, Sunil P John, Peter A Gustafson
BACKGROUND: Neonatal respiratory distress results in > 1 million annual deaths worldwide. Bubble CPAP is a simple, effective, and widely used therapy for infants in respiratory distress. In low-resource settings, more advanced respiratory support is limited by cost, technical expertise, and sporadic electricity. We sought to develop a safe, inexpensive, and simple solution to provide further respiratory support for these infants. METHODS: A standard bubble CPAP system was modified to provide 2 levels of positive airway pressure (bi-level positive airway pressure) by attaching a novel device...
May 30, 2017: Respiratory Care
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