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higher-order aberrations

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https://www.readbyqxmd.com/read/27913232/visual-acuity-and-quality-of-life-in-dry-eye-disease-proceedings-of-the-ocean-group-meeting
#1
José Benítez-Del-Castillo, Marc Labetoulle, Christophe Baudouin, Maurizio Rolando, Yonca A Akova, Pasquale Aragona, Gerd Geerling, Jesús Merayo-Lloves, Elisabeth M Messmer, Kostas Boboridis
Dry eye disease (DED) results in tear film instability and hyperosmolarity, inflammation of the ocular surface and, ultimately, visual disturbance that can significantly impact a patient's quality of life. The effects on visual acuity result in difficulties with driving, reading and computer use and negatively impact psychological health. These effects also extend to the workplace, with a loss of productivity and quality of work causing substantial economic losses. The effects of DED and the impact on vision experienced by patients may not be given sufficient importance by ophthalmologists...
November 29, 2016: Ocular Surface
https://www.readbyqxmd.com/read/27898448/laser-vision-correction-in-treating-myopia
#2
Germano Leal Ehlke, Ronald R Krueger
Myopia is a generally benign refractive error with an increasing prevalence worldwide. It can be corrected temporarily with glasses and contact lenses and permanently with laser vision correction. The 2 main procedures currently being performed for myopia correction are photorefractive keratectomy and laser-assisted in situ keratomileusis. Each technique has its advantages, but they appear to yield similar visual outcomes 1 year after surgery. Laser vision correction for myopia was considered a paradigm shift because healthy eyes could now undergo a surgical procedure to permanently and safely correct the error by altering the center of the cornea, which was previously off limits because of the potential for loss of transparency...
November 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/27897101/platelets-from-glioblastoma-patients-promote-angiogenesis-of-tumor-endothelial-cells-and-exhibit-increased-vegf-content-and-release
#3
Clara Di Vito, Stefania Elena Navone, Giovanni Marfia, Loubna Abdel Hadi, Maria Elisa Mancuso, Alessandro Pecci, Francesco Maria Crisà, Valeria Berno, Paolo Rampini, Rolando Campanella, Laura Riboni
Glioblastoma multiforme (GBM) is the most common and fatal intracranial cancer in humans and exhibits intense and aberrant angiogenesis that sustains its malignancy and involves several angiogenic signals. Among them, vascular endothelial growth factor (VEGF) plays a key role and is overexpressed in GBM. Different cells appear to act as triggers of the aberrant angiogenesis, and, among them, platelets act as key participants. In order to provide further insights into the platelet features and angiogenic role in GBM, this study investigated the effects of platelet releasate on GBM-derived endothelial cells (GECs) and the levels of VEGF and endostatin, as pro- and anti-angiogenic components of platelet releasate from GBM patients...
November 29, 2016: Platelets
https://www.readbyqxmd.com/read/27896533/characteristics-of-higher-order-aberrations-and-anterior-segment-tomography-in-patients-with-pathologic-myopia
#4
Kaori Kasahara, Naoyuki Maeda, Takashi Fujikado, Makoto Tomita, Muka Moriyama, Mutsumi Fuchihata, Kyoko Ohno-Matsui
PURPOSE: To investigate prospectively the characteristics in the higher-order aberrations and anterior segment tomography in patients with pathologic myopia. METHODS: One hundred and twelve consecutive highly myopic patients (mean age 43.4 ± 9.3 years, spherical equivalent of refractive error ≥8 D and an axial length ≥26.5 mm) were studied. Thirty-seven emmetropic individuals (mean age 37.0 ± 14.5 years, spherical equivalent of refractive error ≤ ±1 D) were analyzed as controls...
November 28, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27895998/quantifying-intraocular-scatter-with-near-diffraction-limited-double-pass-point-spread-function
#5
Junlei Zhao, Fei Xiao, Jian Kang, Haoxin Zhao, Yun Dai, Yudong Zhang
Measurement of the double-pass (DP) point-spread function (PSF) can provide an objective and non-invasive method for estimating intraocular scatter in the human eye. The objective scatter index (OSI), which is calculated from the DP PSF images, is commonly used to quantify intraocular scatter. In this article, we simulated the effect of higher-order ocular aberrations on OSI, and the results showed that higher-order ocular aberrations had a significant influence on OSI. Then we developed an adaptive optics DP PSF measurement system (AO-DPPMS) which was capable of correcting ocular aberrations up to eighth-order radial Zernike modes over a 6...
November 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27893524/visual-outcomes-after-smile-lasek-and-lasek-combined-with-corneal-collagen-cross-linking-for-high-myopic-correction
#6
Sangyoon Hyun, Seongjun Lee, Jae-Hyung Kim
PURPOSE: To compare the visual and refractive outcomes of small-incision lenticule extraction (SMILE), laser-assisted subepithelial keratomileusis (LASEK), and LASEK combined with corneal collagen cross-linking (LASEK-CXL) surgery for high-degree myopia. METHODS: Medical records of patients with spherical equivalent (SE) greater than -6.00 diopters (D) treated with SMILE, LASEK, and LASEK-CXL were reviewed. Uncorrected distance visual acuity (UCVA), SE, and corneal haze were followed up in the 3 groups for 6 months...
November 23, 2016: Cornea
https://www.readbyqxmd.com/read/27870872/aberrant-iga1-glycosylation-in-iga-nephropathy-a-systematic-review
#7
Qiang Sun, Zhenhai Zhang, Hong Zhang, Xiaorong Liu
OBJECTIVE: Galactose-deficient IgA1 was evaluated in patients with IgA nephropathy(IgAN) and controls in order to determine the predictive value of galactose-deficient IgA1 in cases of IgA nephropathy. METHODS: PubMed, EMBASE, Cochrane central register of controlled trials, CNKI, CBM disc, and VIP database were searched to identify eligible studies that evaluated a difference in aberrant IgA1 glycosylation in IgAN patients compared with controls. A meta-analysis was conducted to evaluate the impact of galactose-deficient IgA1(Gd-IgA1) levels in different groups...
2016: PloS One
https://www.readbyqxmd.com/read/27867660/corneal-aberrations-contrast-sensitivity-and-light-distortion-in-orthokeratology-patients-1-year-results
#8
Elena Santolaria-Sanz, Alejandro Cerviño, José M González-Méijome
Purpose. To evaluate the corneal higher-order aberrations (HOA), contrast sensitivity function (CSF), and light distortion (LD) in patients undergoing orthokeratology (OK). Methods. Twenty healthy subjects (mean age: 21.40 ± 8 years) with mean spherical equivalent refractive error M = -2.19 ± 0.97 D were evaluated at 1 day, 1 month, and 1 year after starting OK treatment. Monocular LD, photopic monocular CSF, and corneal HOA for 6 mm pupil size were measured. Results. LD showed an increase after the first night (p < 0...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27857374/active-optical-alignment-of-off-axis-telescopes-based-on-nodal-aberration-theory
#9
Xiaobin Zhang, Dong Zhang, Shuyan Xu, Hongcai Ma
Our paper mainly separates the specific aberration contributions of third-order astigmatism and third-order coma from the total aberration fields, on the framework of the modified nodal aberration theory (NAT), for the perturbed off-axis telescope. Based on the derived aberration functions, two alignment models for the same off-axis two-mirror telescope are established and compared. Among them, one is based on third-order NAT, the other is based on fifth-order NAT. By comparison, it is found that the calculated perturbations based on fifth-order NAT are more accurate...
November 14, 2016: Optics Express
https://www.readbyqxmd.com/read/27843230/preclinical-cataract-masquerading-as-post-lasik-regression
#10
Rohit Shetty, Nikhil Negalur, Mathew Kurian, Rushad Shroff
The purpose of this case report is to bring forth a rare clinical scenario where preclinical cataract mimics post-LASIK regression and to describe the role of aberrometry in detecting higher order aberrations (HOAs) and early lens changes. A 36-year-old female presented with blurring of vision since 1 year after having undergone an uneventful LASIK surgery 3 years prior. Corneal topography and aberrometry were within normal limits. Although the lens was morphologically normal on slit lamp examination, increased HOAs and lenticular density were detected...
September 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/27830526/the-stof-a-favorable-geometry-for-a-time-of-flight-analyzer
#11
Daniel M Murphy
A new geometry for the flight region in a time-of-flight mass spectrometer is presented. It consists of two opposing electrostatic sectors of about 255° each and straight sections with a length appropriate to the turns. The resulting geometry folds into a compact space. The first-order aberrations for position, angle, and energy are all zero. The transverse focusing properties are also excellent. For an energetic, high-divergence ion source such as laser ablation, the sTOF has higher resolution and ion transmission than a reflectron of similar physical size...
November 9, 2016: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/27830209/tear-deformation-time-and-optical-quality-in-eyes-wearing-silicone-hydrogel-contact-lenses
#12
Amir Asharlous, Ebrahim Jafarzadehpur, Ali Mirzajani, Mehdi Khabazkhoob, Samira Heydarian, Ali Taghipour
PURPOSE: To evaluate tear film stability and optical aberrations in eyes wearing plano Lotrafilcon B contact lenses (CL). METHODS: Tear Deformation Time (TDT) and aberrometric parameters were assessed in 86 normal emmetropic eyes before and 6 h after wearing CL. RESULT: A statistically significant decrease in TDT and increase in root mean square (RMS) values of higher order aberrations (HOA) were revealed 6 h after CL insertion (both P < 0...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27830203/corneal-aberration-changes-after-rigid-gas-permeable-contact-lens-wear-in-keratokonic-patients
#13
Fereshteh Shokrollahzadeh, Hassan Hashemi, Ebrahim Jafarzadehpur, Ali Mirzajani, Mehdi Khabazkhoob, Abbasali Yekta, Soheila Asgari
PURPOSE: To determine the short-term effect of rigid gas permeable (RGP) contact lenses on corneal aberrations in keratoconic patients. METHOD: Sixteen keratoconic eyes with no history of RGP lens wear were included. They all had corneal aberrometry using Pentacam, and different aberration indices of the anterior and posterior surfaces of the cornea were measured before and 3 months after fitting RGP lenses. The effect of baseline parameters on these changes was tested in univariate and multiple models...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27828859/aberrant-pulvinar-effective-connectivity-in-generalized-social-anxiety-disorder
#14
Reza Tadayonnejad, Heide Klumpp, Olusola Ajilore, Alex Leow, Kinh Luan Phan
Recent neuroimaging findings in general social anxiety disorder (gSAD) have extended our understanding of the neural mechanisms of gSAD beyond an amygdala-centric fear-based hyperactivity model to include other brain regions and networks relevant to salient cues. In particular, higher order areas compromising visual networks that process emotional and social information have been implicated. The pulvinar anchors this network and is a key regulatory node that mediates complex sensory inputs and the integration between limbic and frontal brain systems...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27824376/changes-to-corneal-aberrations-and-vision-after-monovision-in-patients-with-hyperopia-after-using-a-customized-aspheric-ablation-profile-to-increase-corneal-asphericity-q-factor
#15
Romain Courtin, Alain Saad, Alice Grise-Dulac, Emmanuel Guilbert, Damien Gatinel
PURPOSE: To evaluate the visual outcomes and fourth-order Zernike spherical aberrations induced with a customized change in corneal asphericity (ΔQ) correction of presbyopia combined with monovision for hyperopic patients. METHODS: Consecutive hyperopic patients who underwent presbyopic LASIK between September 2013 and July 2014 were included. For the non-dominant eyes, the aspheric ablation profile associated with a myopic refraction was planned using the Custom-Q nomogram (Alcon Laboratories, Inc...
November 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27824375/visual-outcomes-after-lasik-using-topography-guided-vs-wavefront-guided-customized-ablation-systems
#16
Ikuko Toda, Takeshi Ide, Teruki Fukumoto, Kazuo Tsubota
PURPOSE: To evaluate the visual performance of two customized ablation systems (wavefront-guided ablation and topography-guided ablation) in LASIK. METHODS: In this prospective, randomized clinical study, 68 eyes of 35 patients undergoing LASIK were enrolled. Patients were randomly assigned to wavefront-guided ablation using the iDesign aberrometer and STAR S4 IR Excimer Laser system (Abbott Medical Optics, Inc., Santa Ana, CA) (wavefront-guided group; 32 eyes of 16 patients; age: 29...
November 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27818792/smile-and-wavefront-guided-lasik-out-compete-other-refractive-surgeries-in-ameliorating-the-induction-of-high-order-aberrations-in-anterior-corneal-surface
#17
Min-Jie Ye, Cai-Yuan Liu, Rong-Feng Liao, Zheng-Yu Gu, Bing-Ying Zhao, Yi Liao
Purpose. To compare the change of anterior corneal higher-order aberrations (HOAs) after laser in situ keratomileusis (LASIK), wavefront-guided LASIK with iris registration (WF-LASIK), femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK), and small incision lenticule extraction (SMILE). Methods. In a prospective study, 82 eyes underwent LASIK, 119 eyes underwent WF-LASIK, 88 eyes underwent FS-LASIK, and 170 eyes underwent SMILE surgery. HOAs were measured with Pentacam device preoperatively and 6 months after surgery...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27800242/repeatability-and-reproducibility-of-anterior-segment-measurements-in-normal-eyes-using-dual-scheimpflug-analyzer
#18
Zeynep Altıparmak, Ramazan Yağcı, Emre Güler, Zeynel Arslanyılmaz, Metin Canbal, İbrahim F Hepşen
OBJECTIVES: To assess the repeatability and reproducibility of anterior segment measurements including aberrometric measurements provided by a dual Scheimpflug analyzer (Galilei) system in normal eyes. MATERIALS AND METHODS: Three repeated consecutive measurements were taken by two independent examiners. The following were evaluated: total corneal power and posterior corneal power, corneal higher-order wavefront aberrations (6.0 mm pupil), pachymetry at the central, paracentral, and peripheral zones, and anterior chamber depth (ACD)...
December 2015: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27791246/corneal-higher-order-aberrations-after-phacoemulsification-a-comparison-of-3-different-incision-sizes
#19
Christoph von Sonnleithner, Daniel Pilger, David Homburg, Tobias Brockmann, Necip Torun, Eckart Bertelmann
PURPOSE: To analyze the impact of different incision sizes for phacoemulsification on corneal higher-order aberrations (HOA). METHODS: Patients seeking cataract surgery were randomly assigned to one of the following groups: 1.4 mm with biaxial microincision phacoemulsification (25 eyes), 1.8 mm with coaxial phacoemulsification (27 eyes), and 2.2 mm with coaxial phacoemulsification (62 eyes). Inclusion criteria were a minimum age of 18 years and uncomplicated cataract...
October 27, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/27785598/pseudo-accommodation-in-non-amblyopic-children-after-bilateral-cataract-surgery-and-implantation-with-a-monofocal-intraocular-lens-prevalence-and-possible-mechanisms
#20
Charlotte Dénier, Pascal Dureau, Catherine Edelson, Amandine Barjol, Georges Caputo
BACKGROUND: Some pseudophakic patients implanted with a monofocal intraocular lens (IOL) have good near visual acuity (VA) with their distance correction. The objective was to evaluate the prevalence of pseudo-accommodation in children after bilateral cataract surgery, without amblyopia, and to define its mechanisms. METHODS: Observational study that took place in a pediatric ophthalmology department, Paris, France. A total of 68 eyes were included, 40 from 23 children and 28 from 14 adults, with a corrected distance VA above 20/25 and a normal near VA (20/25) with +3 addition...
October 26, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
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