keyword
MENU ▼
Read by QxMD icon Read
search

higher-order aberrations

keyword
https://www.readbyqxmd.com/read/28096651/effects-of-3-diquafosol-sodium-ophthalmic-solution-on-higher-order-aberrations-in-patients-diagnosed-with-dry-eye-after-cataract-surgery
#1
Yasushi Inoue, Shintarou Ochi
PURPOSE: To evaluate the effects of diquafosol sodium ophthalmic solution 3% (DQS) and artificial tears (AT) on higher-order aberrations (HOAs) in patients with dry eye after cataract surgery. DESIGN: This was a post hoc analysis of a previously conducted randomized clinical study. METHODS: Fifty-nine eyes from 42 patients (17 males and 25 females, aged 72.6±8.0 years) with verified or suspected dry eye at 4 weeks after cataract surgery were evaluated...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28087167/lingering-questions-about-enhancer-rna-and-enhancer-transcription-coupled-genomic-instability
#2
REVIEW
Gerson Rothschild, Uttiya Basu
Intergenic and intragenic enhancers found inside topologically associated regulatory domains (TADs) express noncoding RNAs, known as enhancer RNAs (eRNAs). Recent studies have indicated these eRNAs play a role in gene regulatory networks by controlling promoter and enhancer interactions and topology of higher-order chromatin structure. Misregulation of enhancer and promoter associated noncoding RNAs (ncRNAs) could stabilize deleterious secondary DNA structures, noncoding RNA associated DNA/RNA hybrid formation, and promote collisions of transcription complexes with replisomes...
January 10, 2017: Trends in Genetics: TIG
https://www.readbyqxmd.com/read/28076565/effect-of-corneal-biomechanical-properties-on-surgically-induced-astigmatism-and-higher-order-aberrations-after-cataract-surgery
#3
Mustafa Koç, Çağrı İlhan, Yaran Koban, Kemal Özülken, İrfan Durukan, Pelin Yılmazbaş
Purpose: To investigate the relationship between biomechanical properties of the cornea and postoperative refractive changes in patients with low-level astigmatism after cataract surgery. Methods: This prospective study recruited patients undergoing cataract surgery involving 2.8-mm superior incisions. Biomechanical properties of the cornea were evaluated preoperatively using the Ocular Response Analyzer, and corneal profiles were evaluated using a Scheimpflug system (Pentacam HR)...
November 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28068441/changes-in-astigmatism-densitometry-and-aberrations-after-smile-for-low-to-high-myopic-astigmatism-a-12-month-prospective-study
#4
Iben Bach Pedersen, Anders Ivarsen, Jesper Hjortdal
PURPOSE: To evaluate 12-month changes in refraction, visual outcome, corneal densitometry, and postoperative aberrations after small incision lenticule extraction (SMILE) for myopic astigmatism. METHODS: This 12-month prospective clinical trial comprised 101 eyes (101 patients) treated with SMILE for myopic astigmatism with cylinder of 0.75 to 4.00 diopters (D). The preoperative, 1-week, and 1-, 3-, 6-, 9-, and 12-month examinations included measurement of manifest refraction, uncorrected distance visual acuity (UDVA), and corrected (CDVA) distance visual acuity...
January 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28068440/a-prospective-study-to-compare-visual-outcomes-between-wavefront-optimized-and-topography-guided-ablation-profiles-in-contralateral-eyes-with-myopia
#5
Rohit Shetty, Rushad Shroff, Kalyani Deshpande, Roshan Gowda, Sumeet Lahane, Chaitra Jayadev
PURPOSE: To analyze refractive outcomes of wavefront-optimized (WFO) ablation and topography-guided custom ablation (TCAT) profiles using the Allegretto Wave excimer laser platform (Alcon Laboratories, Inc., Fort Worth, TX) in the treatment of myopia. METHODS: Sixty eyes of 30 patients who underwent LASIK were included in this prospective interventional study. WFO ablation was performed in one eye (WFO group) and TCAT in the fellow eye (TCAT group). The WaveLight FS200 femtosecond laser (Alcon Laboratories, Inc...
January 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28068407/significant-association-of-urinary-toxic-metals-and-autism-related-symptoms-a-nonlinear-statistical-analysis-with-cross-validation
#6
James Adams, Daniel P Howsmon, Uwe Kruger, Elizabeth Geis, Eva Gehn, Valeria Fimbres, Elena Pollard, Jessica Mitchell, Julie Ingram, Robert Hellmers, David Quig, Juergen Hahn
INTRODUCTION: A number of previous studies examined a possible association of toxic metals and autism, and over half of those studies suggest that toxic metal levels are different in individuals with Autism Spectrum Disorders (ASD). Additionally, several studies found that those levels correlate with the severity of ASD. METHODS: In order to further investigate these points, this paper performs the most detailed statistical analysis to date of a data set in this field...
2017: PloS One
https://www.readbyqxmd.com/read/28060337/using-rna-sequencing-to-detect-novel-splice-variants-related-to-drug-resistance-in-in-vitro-cancer-models
#7
Rocco Sciarrillo, Anna Wojtuszkiewicz, Irsan E Kooi, Valentina E Gómez, Ugo Boggi, Gerrit Jansen, Gert-Jan Kaspers, Jacqueline Cloos, Elisa Giovannetti
Drug resistance remains a major problem in the treatment of cancer for both hematological malignancies and solid tumors. Intrinsic or acquired resistance can be caused by a range of mechanisms, including increased drug elimination, decreased drug uptake, drug inactivation and alterations of drug targets. Recent data showed that other than by well-known genetic (mutation, amplification) and epigenetic (DNA hypermethylation, histone post-translational modification) modifications, drug resistance mechanisms might also be regulated by splicing aberrations...
December 9, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28060146/combined-effect-of-ocular-and-multifocal-contact-lens-induced-aberrations-on-visual-performance-center-distance-versus-center-near-design
#8
Daniela Lopes-Ferreira, Paulo Fernandes, António Queirós, José M González-Meijome
PURPOSE: To evaluate the combined effects of inherent ocular aberrations and induced aberrations with a multifocal soft contact lens (MFCL) after 15 days of lens wear in presbyopic participants and their influence on visual performance at distance and near under high and low contrast conditions. METHODS: Forty presbyopic participants (mean age, 48.7±3.4) presenting a mean addition of 1.53±0.58 D were fitted with Biofinity Multifocal (CooperVision) and included in the study...
January 4, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28060075/removal-and-repositioning-of-intracorneal-ring-segments-improving-corneal-topography-and-clinical-outcomes-in-keratoconus-and-ectasia
#9
Kahei Chan, Peter S Hersh
PURPOSE: To evaluate the efficacy of removal and relocation of intracorneal ring segments for improving outcomes in treatment of keratoconus and corneal ectasia. METHODS: This is a retrospective case series conducted at a cornea and refractive surgery subspecialty practice setting. Patients with previous insertion of 2 intracorneal ring segments underwent surgical removal and repositioning of segments because of unsatisfactory visual and topographic outcomes. The principal outcomes included uncorrected and corrected visual acuities, manifest refraction, topography-derived maximum keratometry (Kmax), inferior-superior topography power difference (I - S), and higher-order aberration profile derived from wavefront analysis...
February 2017: Cornea
https://www.readbyqxmd.com/read/28040524/corneal-higher-order-aberrations-in-infectious-keratitis
#10
Eisuke Shimizu, Takefumi Yamaguchi, Yukari Yaguchi, Murat Dogru, Yoshiyuki Satake, Kazuo Tsubota, Jun Shimazaki
PURPOSE: To characterize the corneal higher-order aberrations (HOAs) in eyes with acanthoamoeba keratitis (AK), bacterial keratitis (BK), and fungal keratitis (FK). DESIGN: Retrospective consecutive case series. METHODS: This retrospective study includes 18 normal subjects and 63 eyes of 62 consecutive patients with corneal scarring due to AK (20 eyes), BK (35 eyes) and FK (8 eyes) from 2010 to 2016. HOAs of the anterior and posterior surfaces and the total cornea were analyzed by anterior segment optical coherence tomography (AS-OCT)...
December 28, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28024242/aneugenicity-and-clastogenicity-in-freshwater-fish-oreochromis-niloticus-exposed-to-incipient-safe-concentration-of-tannery-effluent
#11
Abel Weldetinsae, Mekibib Dawit, Abebe Getahun, H S Patil, Esayas Alemayehu, Melaku Gizaw, Moa Abate, Daniel Abera
Conventional effluent bioassays mostly rely on overt responses or endpoints such as apical and Darwinian fitness. Beyond the empirical observation, laboratory toxicity testing needs to rely on effective detection of prognostic biomarkers such as genotoxicity. Indeed, characterization of tannery effluent requires slotting in of genotoxic responses in whole effluent toxicity testing procedures. Hence, the prime objective of the present experimental investigation is to apply the technique of biological assay as a tool of toxicity testing to evaluate the induction of micronuclei (MN) in peripheral erythrocytes, and exfoliated cells of gill and kidney of O...
December 23, 2016: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28003980/effect-of-incision-types-for-artisan-phakic-intraocular-lens-implantation-on-ocular-higher-order-aberrations
#12
Young Min Park, Bong Joon Choi, Jong Soo Lee
AIM: To evaluate the effect of incision types for Artisan phakic intraocular lens (PIOL) implantation on ocular higher-order aberrations (HOAs). METHODS: A retrospective review was conducted of the patients who had undergone Artisan PIOL implantation for the correction of myopia and followed up for at least 6mo. Patients are classified into 2 groups considering the incision type: cornea group with patients undergone clear corneal incision; sclera group with patients undergone sclera tunnel incision...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27994802/comparison-of-higher-order-aberrations-after-wavefront-guided-lasik-and-prk-one-year-follow-up-results
#13
Seyed Hamid Reza Jahadi Hosseini, Seyed Mohammad Bagher Abtahi, Mohammad Reza Khalili
PURPOSE: To evaluate the changes and predictability of higher order aberrations (HOAs) after personalized laser in situ keratomileusis (LASIK) and personalized photorefractive keratectomy (PRK) for simple myopia and compound myopic astigmatism. METHODS: In this prospective cross-sectional study, 100 eyes were included. A total of 50 eyes underwent personalized LASIK and 50 eyes underwent personalized PRK. Preoperative and postoperative wavefront data were compared between the two groups...
October 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27956283/single-step-transepithelial-photorefractive-keratectomy-in-myopia-and-astigmatism-18-month-follow-up
#14
Soheil Adib-Moghaddam, Saeed Soleyman-Jahi, Bahram Salmanian, Amir-Houshang Omidvari, Fatemeh Adili-Aghdam, Farsad Noorizadeh, Medi Eslani
PURPOSE: To evaluate the long-term quantitative and qualitative optical outcomes of 1-step transepithelial photorefractive keratectomy (PRK) to correct myopia and astigmatism. SETTING: Bina Eye Hospital, Tehran, Iran. DESIGN: Prospective interventional case series. METHODS: Eyes with myopia with or without astigmatism were evaluated. One-step transepithelial PRK was performed with an aberration-free aspheric optimized profile and the Amaris 500 laser...
November 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27941045/single-step-transepithelial-versus-alcohol-assisted-photorefractive-keratectomy-in-the-treatment-of-high-myopia-a-comparative-evaluation-over-12%C3%A2-months
#15
Rafic Antonios, Maamoun Abdul Fattah, Samuel Arba Mosquera, Bachir H Abiad, Karim Sleiman, Shady T Awwad
BACKGROUND/AIMS: To evaluate refractive outcomes of single-step transepithelial photorefractive keratectomy (TransPRK) versus alcohol-assisted PRK (EtOH-PRK) for the correction of high myopia. METHODS: This was a retrospective non-randomised comparative study conducted at the American University of Beirut Medical Center, Beirut, Lebanon. Eyes with myopia (spherical equivalent (SE) larger than -6.00 D) that had undergone EtOH-PRK treatment combined with mitomycin C and TransPRK (SE: -7...
December 9, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27938951/outcomes-of-photorefractive-keratectomy-following-laser-in-situ-keratomileusis-a-cohort-study
#16
Alfonso Iovieno, Joshua C Teichman, Stephanie Low, Sonia N Yeung, Marie Eve Lègarè, Alejandro D Lichtinger, Allan R Slomovic, David S Rootman
OBJECTIVE: To analyze the outcomes of photorefractive keratectomy (PRK) on residual myopia and hyperopia post-laser in situ keratomileusis (LASIK) and to compare these results with PRK on eyes without previous laser refractive surgery. DESIGN: Retrospective comparative cohort study. PARTICIPANTS: Patients undergoing PRK between 2006 and 2010 were reviewed. METHODS: Patients were divided into 4 groups, myopic or hyperopic PRK post-LASIK (mPRK-PL and hPRK-PL, respectively) and myopic or hyperopic PRK on corneas without previous laser refractive surgery (mPRK and hPRK, respectively)...
December 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27930793/intracorneal-ring-segments-implantation-for-corneal-ectasia
#17
Natalia T Giacomin, Glauco R Mello, Carla S Medeiros, Alyin Kiliç, Cristine C Serpe, Hirlana G Almeida, Newton Kara-Junior, Marcony R Santhiago
PURPOSE: To provide an overview of the predictability, safety, and efficacy of intrastromal corneal ring segment (ICRS) implantation as a tool to improve visual acuity and its association with other techniques such as corneal collagen cross-linking (CXL), addressing biomechanical outcomes, models, surgical planning and technique, indications, contraindications, and complications in ectatic corneas. METHODS: Literature review. RESULTS: ICRSs have been used to regularize the corneal shape and reduce corneal astigmatism and higher order aberrations, improve visual acuity to acceptable limits, and delay, or eventually prevent, a corneal keratoplasty in keratoconic eyes...
December 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27918353/removal-and-repositioning-of-intracorneal-ring-segments-improving-corneal-topography-and-clinical-outcomes-in-keratoconus-and-ectasia
#18
Kahei Chan, Peter S Hersh
PURPOSE: To evaluate the efficacy of removal and relocation of intracorneal ring segments for improving outcomes in treatment of keratoconus and corneal ectasia. METHODS: This is a retrospective case series conducted at a cornea and refractive surgery subspecialty practice setting. Patients with previous insertion of 2 intracorneal ring segments underwent surgical removal and repositioning of segments because of unsatisfactory visual and topographic outcomes. The principal outcomes included uncorrected and corrected visual acuities, manifest refraction, topography-derived maximum keratometry (Kmax), inferior-superior topography power difference (I - S), and higher-order aberration profile derived from wavefront analysis...
December 1, 2016: Cornea
https://www.readbyqxmd.com/read/27916313/influence-of-the-flap-on-outcomes-in-corneal-refractive-surgery-with-femtosecond-laser-smile-vs-flex
#19
J L Alió, M El Bahrawy, A Angelov, D Ortiz, P Yébana
OBJECTIVE: To investigate the influence of creating a flap on the postoperative optical quality of the cornea in terms of predicted corneal curvature and Seidel aberrations after 2 modalities of femtosecond assisted corneal lenticule extraction laser for the correction of myopia and myopic astigmatism: The flapless procedure small incision lenticular extraction (SMILE) and the flap-based femtosecond lenticular extraction (FLEx). METHODS: The study is a prospective consecutive non-randomised comparative interventional case series including 64 eyes with myopic or myopic astigmatism refractive errors...
December 1, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27913232/visual-acuity-and-quality-of-life-in-dry-eye-disease-proceedings-of-the-ocean-group-meeting
#20
José Benítez-Del-Castillo, Marc Labetoulle, Christophe Baudouin, Maurizio Rolando, Yonca A Akova, Pasquale Aragona, Gerd Geerling, Jesús Merayo-Lloves, Elisabeth M Messmer, Kostas Boboridis
Dry eye disease (DED) results in tear film instability and hyperosmolarity, inflammation of the ocular surface and, ultimately, visual disturbance that can significantly impact a patient's quality of life. The effects on visual acuity result in difficulties with driving, reading and computer use and negatively impact psychological health. These effects also extend to the workplace, with a loss of productivity and quality of work causing substantial economic losses. The effects of DED and the impact on vision experienced by patients may not be given sufficient importance by ophthalmologists...
November 29, 2016: Ocular Surface
keyword
keyword
104440
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"