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studies on hysterectomy

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https://www.readbyqxmd.com/read/29326183/transvaginal-natural-orifice-transluminal-endoscopic-surgery-vnotes-adnexectomy-for-benign-pathology-compared-with-laparoscopic-excision-notable-a-protocol-for-a-randomised-controlled-trial
#1
Jan Filip Baekelandt, Peter A De Mulder, Ilse Le Roy, Chantal Mathieu, Annouschka Laenen, Paul Enzlin, Steven Weyers, Ben W J Mol, Jan J A Bosteels
INTRODUCTION: Natural orifice transluminal endoscopic surgery (NOTES) uses natural orifices to access the cavities of the human body to perform surgical interventions. NOTES limits the magnitude of surgical trauma and potentially reduces postoperative pain. Our group published a protocol on a randomised study comparing transvaginal NOTES (vNOTES) versus laparoscopy for hysterectomy (HALON). We simultaneously designed a similar randomised controlled trial (RCT) comparing vNOTES with laparoscopy for adnexectomy...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29324569/does-the-vaginal-flora-modify-when-a-synthetic-mesh-is-used-for-genital-prolapse-repair-in-postmenopausal-women-a-pilot-randomized-controlled-study
#2
Edilson Benedito de Castro, Luiz Gustavo Oliveria Brito, Paulo César Giraldo, Cássia Raquel Teatin Juliato
OBJECTIVE: The vaginal flora from postmenopausal women with pelvic organ prolapse (POP) is different from younger women. We hypothesized that the decision of a surgical route using a mesh would modify the vaginal flora. The purpose of this study was to analyze the vaginal flora from postmenopausal women that were submitted to abdominal sacrocervicopexy or vaginal sacrospinous fixation. METHODS: A pilot, randomized controlled study with 50 women aged 55 to 75 years (n = 25; abdominal sacrocervicopexy + subtotal hysterectomy; n = 25 vaginal sacrospinous fixation + vaginal hysterectomy) was performed...
January 10, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29324534/reproductive-outcomes-after-gestational-trophoblastic-neoplasia-a-comparison-between-single-agent-and-multiagent-chemotherapy-retrospective-analysis-from-the-mito-9-group
#3
Raffaella Cioffi, Alice Bergamini, Angiolo Gadducci, Gennaro Cormio, Veronica Giorgione, Micaela Petrone, Emanuela Rabaiotti, Francesca Pella, Massimo Candiani, Giorgia Mangili
OBJECTIVES: Gestational trophoblastic neoplasia affects women of reproductive age and is usually treated by chemotherapy. Major concerns related to chemotherapy in young women are the possible infertility, risk of early menopause, and teratogenic effects on subsequent pregnancies. The study's aim was to analyze menstrual and reproductive outcomes of women treated with single-agent versus multiagent chemotherapy for gestational trophoblastic neoplasia. METHODS: One-hundred fifty-one patients were treated...
January 10, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29306241/the-relationship-between-the-trendelenburg-position-and-cerebral-hypoxia-inpatients-who-have-undergone-robot-assisted-hysterectomy-and-prostatectomy
#4
Ali Özgün, Asuman Sargın, Semra Karaman, İlkben Günüşen, Işık Alper, Fatma Zekiye Aşkar
Background/aim: This study aimed to evaluate the relationship between the Trendelenburg position and cerebral hypoxia in robot-assisted hysterectomy and prostatectomy.Materials and methods: A standardized mini-mental state examination was administered to 50 patients enrolled in the study 1 h before and after surgery. Near infrared spectroscopy (NIRS) values and hemodynamic and respiratory parameters were recorded after induction of anesthesia (baseline) and once every 20 min in the Trendelenburg position and supine positions...
December 19, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29304867/predictors-of-hysterectomy-among-married-women-15-49%C3%A2-years-in-india
#5
Ranjan Kumar Prusty, Chetan Choithani, Shiv Dutt Gupta
BACKGROUND: In India, community based studies and media reports indicate a surge in the number of young women undergoing hysterectomy in the past few years. This has led to suspicion on the misuse of procedure, and intense debates on its potential ill health-effects on young women. However, there are no population-based studies that provide insights into hysterectomy prevalence and its determinants at the national level. DATA AND METHODS: This study used data from India's District Level Household Survey that involved a sample of 3, 16,361 married women in the age group of 15-49 years spread across 21 States and Union Territories of India...
January 5, 2018: Reproductive Health
https://www.readbyqxmd.com/read/29304224/in-vitro-differentiation-of-human-oocyte-like-cells-from-oogonial-stem-cells-single-cell-isolation-and-molecular-characterization
#6
Erica Silvestris, Paola Cafforio, Stella D'Oronzo, Claudia Felici, Franco Silvestris, Giuseppe Loverro
STUDY QUESTION: Are the large cells derived from cultured DEAD box polypeptide 4 (DDX4)-positive oogonial stem cells (OSCs), isolated from the ovarian cortex of non-menopausal and menopausal women, oocyte-like cells? SUMMARY ANSWER: Under appropriate culture conditions, DDX4-positive OSCs from non-menopausal and menopausal women differentiate into large haploid oocyte-like cells expressing the major oocyte markers growth differentiation factor 9 (GDF-9) and synaptonemal complex protein 3 (SYCP3) and then enter meiosis...
January 3, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29302807/laparoscopic-assisted-vaginal-hysterectomy-versus-vaginal-hysterectomy-for-benign-uterine-diseases-a-prospective-randomized-multicenter-double-blind-trial-lava
#7
H Eggemann, A Ignatov, H Frauchiger-Heuer, T Amse, S D Costa
OBJECTIVE: To compare the impact of peritoneal closure on postoperative pain after vaginal (VH) and laparoscopic-assisted vaginal hysterectomy (LAVH). STUDY DESIGN: A prospective, randomized, double-blind study was designed to investigate as primary outcome the postoperative pain after VH and LAVH with and without peritoneal closure. The postoperative pain was measured using visual analogue scale (VAS). RESULTS: The patients were recruited between August, 2007 and July, 2014...
January 4, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29296049/hysterectomy-and-ovarian-cystectomy-using-natural-orifice-transluminal-endoscopic-surgery-an-initial-experience-at-tzu-chi-general-hospital
#8
Dah-Ching Ding, Tang-Yuan Chu, Mun-Kun Hong
Objectives: The objective of this study is to report our initial experience with patients undergoing transvaginal natural orifice transluminal endoscopic surgery (NOTES). Materials and Methods: From September 2016 to December 2016, patients who were not virgins and did not have pelvic inflammation or obliteration of the cul-de-sac who underwent NOTES hysterectomy or ovarian cystectomy (OC) were included in the study. Results: Transvaginal NOTES was performed smoothly in six patients, two patients (mean age 35 years, mean body mass index [BMI] 25) received an OC and four patients (mean age 49 years, mean BMI 27) underwent a hysterectomy...
October 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29290995/effectiveness-of-adjuvant-systemic-chemotherapy-for-intermediate-risk-stage-ib-cervical-cancer
#9
Koji Matsuo, Muneaki Shimada, Harushige Yokota, Toyomi Satoh, Hidetaka Katabuchi, Shoji Kodama, Hiroshi Sasaki, Noriomi Matsumura, Mikio Mikami, Toru Sugiyama
Objective: To examine the effectiveness of systemic chemotherapy following radical hysterectomy for women with intermediate-risk stage IB cervical cancer. Materials and Methods: This is a retrospective analysis of a previously organized nation-wide cohort study examining 6,003 women with stage IB-IIB cervical cancer who underwent radical hysterectomy between 2004 and 2008 in Japan. Survival of 555 women with stage IB cervical cancer in the intermediate-risk group (deep stromal invasion > 50%, large tumor size > 4 cm, and lympho-vascular space invasion [LVSI]) were examined based on adjuvant therapy patterns: chemotherapy alone (n = 223, 40...
December 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/29289989/the-use-of-barbed-sutures-for-vaginal-cuff-closure-during-laparoscopic-hysterectomy
#10
Su Mi Kim, Jong Min Baek, Jae Yen Song, Sung Jong Lee, Eun Kyung Park, Chan Joo Kim, Yong Seok Lee
PURPOSE: To compare surgical outcomes and complications of 334 women who underwent total laparoscopic hysterectomy with or without the use of barbed sutures for vaginal cuff closure. METHODS: A retrospective study was conducted on a cohort of women who underwent total laparoscopic hysterectomy for benign gynecologic diseases at Dae-Jeon St. Mary's Hospital, between May 2009 and May 2016. Surgical outcomes and complications were compared between the two groups. RESULTS: A total of 334 women were included: 212 cases of vaginal cuff suture performed with traditional suture material and 122 cases of vaginal cuff suture performed with the barbed suture...
December 30, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29289471/-laparoscopic-sacrocolpopexy-for-exteriorized-pelvic-organ-prolapse-mid-term-functional-results
#11
B André, O Jourdain, P Guerby, F Vidal, F Léonard
OBJECTIVES: To assess feasibility and postoperative outcomes associated with laparoscopic sacrocolpopexy in patients presenting with exteriorized pelvic organ prolapse (stage>3). METHODS: Prospective study involving patients undergoing laparoscopic sacrocolpopexy for advanced stage pelvic organ prolapse. Symptoms and quality of life were evaluated at baseline and at 1, 4 and 18 months after surgery using validated questionnaires (PFDI-20 and PFIQ-7). RESULTS: Sixty-three patients were included between September 2012 and January 2014...
December 27, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29288346/the-manchester-fothergill-procedure-versus-vaginal-hysterectomy-with-uterosacral-ligament-suspension-a-matched-historical-cohort-study
#12
Cæcilie Krogsgaard Tolstrup, Karen Ruben Husby, Gunnar Lose, Tine Iskov Kopp, Petra Hall Viborg, Ulrik Schiøler Kesmodel, Niels Klarskov
INTRODUCTION AND HYPOTHESIS: This study compares vaginal hysterectomy with uterosacral ligament suspension (VH) with the Manchester-Fothergill procedure (MP) for treating pelvic organ prolapse (POP) in the apical compartment. METHODS: Our matched historical cohort study is based on data from four Danish databases and the corresponding electronic medical records. Patients with POP surgically treated with VH (n = 295) or the MP (n = 295) in between 2010 and 2014 were matched for age and preoperative POP stage in the apical compartment...
December 29, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/29285144/icaritin-inhibits-decidualization-of-endometrial-stromal-cells
#13
Aiwen Le, Zhong Hai Wang, Xiao Yun Dai, Tian Hui Xiao, Rong Zhuo, Baozhen Zhang, Zhonglin Xiao, Xiujun Fan
The aim of the present study was to investigate the effects of Icaritin on the proliferation and decidualization of endometrial stromal cells (ESCs). A total of 20 specimens of endometrium were collected during hysterectomy at the Gynecology Department of Shenzhen Nanshan People's Hospital (Shenzhen, China) between August 2014 and December 2015. The endometrium was digested with high concentrations of collagenase and DNase and filtered with meshes, and then the glandular epithelial and stromal cells were separated by the adhesion purification method...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29273307/sentinel-lymph-node-biopsy-in-endometrial-cancer-feasibility-safety-and-lymphatic-complications
#14
Barbara Geppert, Céline Lönnerfors, Michele Bollino, Jan Persson
OBJECTIVE: To compare the rate of lymphatic complications in women with endometrial cancer undergoing sentinel lymph node biopsy versus a full pelvic and infrarenal paraaortic lymphadenectomy, and to examine the overall feasibility and safety of the former. METHODS: A prospective study of 188 patients with endometrial cancer planned for robotic surgery. Indocyanine green was used to identify the sentinel lymph nodes. In low-risk patients the lymphadenectomy was restricted to removal of sentinel lymph nodes whereas in high-risk patients also a full lymphadenectomy was performed...
December 20, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29246636/total-laparoscopic-hysterectomy-with-pelvic-aortic-lymph-node-dissection-for-endometrial-cancer-using-passive-instrument-positioners-a-retrospective-case-control-series
#15
Scott M Eisenkop
OBJECTIVE: To investigate influences of Passive instrument positioners on laparoscopic operative outcomes for endometrial cancer relative to other independent variables. DESIGN: Retrospective case-controlled study (Canadian Task Force Classification II-2). SETTING: Laparoscopies performed by author in multiple community hospitals. PATIENTS: Consecutive patients of 297 from December 2009 to October 2016 with clinically isolated endometrial cancer or retroperitoneal lymphadenopathy on imaging studies...
December 12, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29246556/uterus-transplantation-robotic-surgeon-perspective
#16
Hubert Fornalik, Nicole Fornalik
OBJECTIVE: To study the safety and feasibility of robotic dissection of deep pelvic vessels as applied to the robotic harvesting of a uterus from live transplant donor. DESIGN: Surgical video. SETTING: Gynecologic oncology practice of a tertiary community cancer center. PATIENT(S): Two patients undergoing robotic nerve-sparing radical hysterectomy for International Federation of Gynecology and Obstetrics (FIGO) stage Ib1 cervical cancer...
December 12, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29245257/endometrial-stromal-sarcoma-in-combination-with-mixed-type-endometrial-carcinomas-a-case-report-and-literature-review
#17
REVIEW
Xiao-Xin Xiu, Hua-Li Wang, Lv Yun-Yi, Kong Fan-Dou, Hou Jin-Ping
RATIONALE: Endometrial stromal sarcoma (ESS) is rare, representing only approximately 0.2% of all uterine malignancies. Mixed type endometrial carcinomas (MT-ECs) are rare tumors with both type I and II features, and are difficult to diagnose. Cases of ESS and MT-ECs coexisting in the same patient are extremely rare. This study aimed to describe a case of ESS in combination with MT-ECs in a 47-year-old premenopausal woman. PATIENT CONCERNS: A woman presented to the hospital complaining of occasional abdominal pain and had high tumor markers: cancer antigen (CA) 19-9 (263...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29242958/impact-of-radical-hysterectomy-on-the-transobturator-sling-pathway-a-retrospective-three-dimensional-magnetic-resonance-imaging-study
#18
Jinyang Chen, Chunlin Chen, Yige Li, Lan Chen, Juan Xu, Ping Liu
INTRODUCTION AND HYPOTHESIS: Morphological and functional anomalies of the urethra may cause stress urinary incontinence after radical hysterectomy (RH). We introduce a novel three-dimensional (3D) magnetic resonance imaging (MRI) technique to assess the impact of RH on the transobturator sling pathway. METHODS: 3D-MRI reconstruction models were retrospectively developed for the measurement of various parameters before and after RH, including puncture angle, orientation and distance from the midurethral puncture site to the obturator membrane (DUO), in 31 patients with cervical cancer...
December 14, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/29241920/learning-curve-in-concurrent-application-of-laparoscopic-and-robotic-assisted-hysterectomy-with-lymphadenectomy-in-endometrial%C3%A2-cancer
#19
Pao-Ling Torng, Song-Po Pan, Jing-Shiang Hwang, Ho-Jun Shih, Chi-Ling Chen
OBJECTIVE: To evaluate the concurrent interaction of laparoscopic and robotic-assisted surgery in the initial learning period of endometrial cancer staging. MATERIALS AND METHODS: A retrospective cohort study was performed for the first 44 consecutive patients with endometrial cancer underwent laparoscopic (LSS) or robotic-assisted staging surgery (RSS) from February 2012 to October 2015 by a single surgeon in a tertiary care referral hospital. Demographics, diagnosis, perioperative variables, and complications were recorded...
December 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29240603/what-is-the-optimal-adjuvant-treatment-sequence-for-node-positive-endometrial-cancer-results-of-a-national-cancer-database-analysis
#20
Ankit Modh, Ahmed I Ghanem, Charlotte Burmeister, Rabbie K Hanna, Mohamed A Elshaikh
OBJECTIVE: The optimal sequence of administering chemotherapy (CT) and radiation treatment (RT) in women with node-positive endometrial carcinoma (EC) remains controversial. We used the National Cancer Database to evaluate overall survival (OS) in women with advanced EC receiving different sequences of adjuvant therapy. METHODS: The National Cancer Database was queried for female adults with International Federation of Gynecology and Obstetrics 2009 stage IIIC1 to IIIC2 EC diagnosed from 2004 to 2012 treated with hysterectomy and adjuvant CT and RT...
December 13, 2017: International Journal of Gynecological Cancer
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