Yong Kang, Lingling Xu, Jinrui Dong, Xue Yuan, Jiamin Ye, Yueyue Fan, Bing Liu, Julin Xie, Xiaoyuan Ji
Chronic diabetic wounds are at lifelong risk of developing diabetic foot ulcers owing to severe hypoxia, excessive reactive oxygen species (ROS), a complex inflammatory microenvironment, and the potential for bacterial infection. Here we develop a programmed treatment strategy employing live Haematococcus (HEA). By modulating light intensity, HEA can be programmed to perform a variety of functions, such as antibacterial activity, oxygen supply, ROS scavenging, and immune regulation, suggesting its potential for use in programmed therapy...
February 3, 2024: Nature Communications