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https://www.readbyqxmd.com/read/29350019/cypress-pollen-allergy-is-responsible-for-two-distinct-phenotypes-of-allergic-rhinitis-different-from-other-pollinosis
#1
L Pahus, M Gouitaa, T Sofalvi, K Alagha, D Gras, P Chanez, D Charpin
Different phenotypes of allergic rhinitis have been identified based on the seasonality of the allergen involved. Within pollinosis, importance has to be paid to the responsible pollen species. Guidelines for clinical management are mostly based on studies performed in patients with grass pollen allergy. Only few data is available on tree pollen allergy and more specifically on cypress pollen allergy. We focused on the clinical and biological features of cypress pollen allergy to determine whether it is associated with a specific phenotype of allergic rhinitis or not...
January 2018: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29342449/increased-use-of-adrenaline-in-the-management-of-childhood-anaphylaxis-over-the-last-decade
#2
Kristina Rueter, Brennan Ta, Natasha Bear, Michaela Lucas, Meredith L Borland, Susan L Prescott
BACKGROUND: We recently determined that allergy training programs have improved physician recognition and diagnosis of pediatric anaphylaxis in the last decade. OBJECTIVE: To investigate for changes in management, in particular the appropriate use of adrenaline for the treatment of anaphylaxis in a tertiary pediatric emergency department (PED). METHODS: We conducted a retrospective case note study including children aged 0 to 16 years coded and verified for anaphylaxis comparing cases in years 2003/2004 with 2012...
January 13, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29341512/food-allergy-emergencies-in-children-to-what-extent-are-early-years-services-prepared-a-cross-sectional-survey
#3
S MacGiobuin, V Stitt, D Philbin, B Higgins, G McGuire, A M O'Regan, M Kelly
Food allergies are common in preschool children. This study's aims are to establish prevalence, to clarify management practices, levels of preparedness and the perceived role of General Practitioners amongst Early Years Services providers. This study is an anonymous, quantitative, cross sectional study. An online questionnaire was distributed to 282 Early Years Service providers. Data were analysed using SPSS. Response rate was 35% (n=98). Prevalence of food allergy was 3% (n=119). Allergic reactions to food had occurred on site in 16% (n=15)...
August 8, 2017: Irish Medical Journal
https://www.readbyqxmd.com/read/29336054/the-eaaci-ga%C3%A2-len-edf-wao-guideline-for-the-definition-classification-diagnosis-and-management-of-urticaria-the-2017-revision-and-update
#4
T Zuberbier, W Aberer, R Asero, A H Abdul Latiff, D Baker, B Ballmer-Weber, J A Bernstein, C Bindslev-Jensen, Z Brzoza, R Buense Bedrikow, G W Canonica, M K Church, T Craig, I V Danilycheva, C Dressler, L F Ensina, A Giménez-Arnau, K Godse, M Gonçalo, C Grattan, J Hebert, M Hide, A Kaplan, A Kapp, C H Katelaris, E Kocatürk, K Kulthanan, D Larenas-Linnemann, T A Leslie, M Magerl, P Mathelier-Fusade, R Y Meshkova, M Metz, A Nast, E Nettis, H Oude-Elberink, S Rosumeck, S S Saini, M Sánchez-Borges, P Schmid-Grendelmeier, P Staubach, G Sussman, E Toubi, G A Vena, C Vestergaard, B Wedi, R N Werner, Z Zhao, M Maurer
This evidence and consensus-based guideline was developed following the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. The conference was held on December 1st, 2016. It is a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), the EU-founded network of excellence, the Global Allergy and Asthma European Network (GA²LEN), the European Dermatology Forum (EDF), and the World Allergy Organization (WAO) with the participation of 48 delegates of 42 national and international societies...
January 15, 2018: Allergy
https://www.readbyqxmd.com/read/29335327/gps-experiences-of-diagnosing-and-managing-childhood-eczema-a-qualitative-study-in-primary-care
#5
Emma Le Roux, Kingsley Powell, Jonathan P Banks, Matthew J Ridd
BACKGROUND: Eczema is common among children, and in the UK the majority are managed by GPs. The most common cause of poor disease control is incorrect use of topical treatments. There is a lack of research into the challenges faced by GPs in diagnosing and managing this condition. AIM: To explore the experiences of GPs in assessing and managing children with eczema. DESIGN AND SETTING: Qualitative study in primary care in England. METHOD: Semi-structured interviews with 15 GPs were audiorecorded, transcribed verbatim, and analysed thematically using the framework method...
January 15, 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29331100/prevalence-associated-factors-and-control-level-of-asthma-symptoms-among-adolescents-in-northern-jordan
#6
Nihaya A Al-Sheyab, Mahmoud A Alomari
Objective To investigate the prevalence, associated factors, and control level of asthma in Jordanian high school students. Methods A descriptive, comparative, cross sectional design was used and a cluster sample of 2691 students (mean age = 14.5 years, 51.0% girls), drawn from eight randomly selected public high schools in Northern Jordan, participated in the study. Each student had the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire completed in the classroom between February and May, 2015...
January 13, 2018: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/29329877/-attitudes-towards-cow-s-milk-protein-allergy-management-by-spanish-gastroenterologist
#7
Alicia Isabel Pascual Pérez, Alejandra Méndez Sánchez, Óscar Segarra Cantón, Beatriz Espin Jaime, Santiago Jiménez Treviño, Carlos Bousoño García, Juan José Díaz Martín
INTRODUCTION: Food allergy is an increasing health problem in the developed world. Cow's milk protein is the main cause of food allergy in infants. Without an appropriate diagnostic workup, there is a high risk of both over- and underdiagnosis and therefore, over and undertreatment. The objective of our study was to analyze the variability in cow's milk protein allergy (CMPA) management by pediatric gastroenterologists in Spain. METHODS: A fifty item questionnaire, including open and closed items in a Likert's scale from 0 to 5, was drafted and distributed through the Spanish Society for Pediatric Gastroenterology, Hepatology and Nutrition (SEGHNP) e-mail list...
January 9, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29325984/minimally-invasive-repair-of-pectus-carinatum
#8
Mustafa Yuksel, Tunc Lacin, Nezih Onur Ermerak, Esra Yamansavci Sirzai, Bihter Sayan
BACKGROUND: The second most common deformity of the anterior chest wall, pectus carinatum, is a diverse deformity that has been largely managed using open techniques. This study reviews clinical experience with a newly designed bar for minimally invasive repair of pectus carinatum. METHODS: We reviewed the records of all patients recorded in our Chest Wall Deformities Clinical Database. Between January 2006 and November 2016, minimally invasive repair of pectus carinatum was performed in 172 patients...
January 9, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29319881/systemic-il-2-anti-il-2ab-complex-combined-with-sublingual-immunotherapy-suppresses-experimental-food-allergy-in-mice-through-induction-of-mucosal-regulatory-t-cells
#9
Paola L Smaldini, Fernando Trejo, José L Cohen, Eliane Piaggio, Guillermo H Docena
Therapeutic tolerance restoration has been proven to modify food allergy in patients and animal models and although sublingual immunotherapy (SLIT) has showed promise, combined therapy may be necessary to achieve a strong and long-term tolerance. In this work, we combined SLIT with systemic administration of IL-2 associated with an anti-IL-2 monoclonal antibody (IL-2/anti-IL-2Ab complex or IL-2C) to reverse the IgE-mediated experimental allergy. Balb/c mice were sensitized with cholera toxin and milk proteins and orally challenged with allergen to elicit hypersensitivity reactions...
January 10, 2018: Allergy
https://www.readbyqxmd.com/read/29318628/the-international-wao-eaaci-guideline-for-the-management-of-hereditary-angioedema-the-2017-revision-and-update
#10
Marcus Maurer, Markus Magerl, Ignacio Ansotegui, Emel Aygören Pürsün, Stephen Betschel, Konrad Bork, Tom Bowen, Henrik Balle Boysen, Henriette Farkas, Anete Grumach, Michihiro Hide, Constance Katelaris, Richard Lockey, Hilary Longhurst, William Lumry, Inmaculada Martinez-Saguer, Dumitru Moldovan, Alexander Nast, Ruby Pawankar, Paul Potter, Marc Riedl, Bruce Ritchie, Lanny Rosenwasser, Mario Sánchez-Borges, Yuxiang Zhi, Bruce Zuraw, Timothy Craig
Hereditary angioedema (HAE) is a rare disease and a serious health problem, globally and for affected patients and their families. The pathophysiological background is primarily a vascular reaction to an overshooting local production of bradykinin. Evidence-based recommendations are needed to inform and guide clinical decision makers. This is the first revision and update of the global guideline for the diagnosis and management of HAE[5]. It was developed by the World Allergy Organization (WAO) in collaboration with the European Academy of Allergy and Clinical Immunology (EAACI)...
January 10, 2018: Allergy
https://www.readbyqxmd.com/read/29318625/consensus-document-on-dog-and-cat-allergy
#11
REVIEW
Ignacio Davila, Javier Domínguez-Ortega, Ana Mª Navarro Pulido, Alicia Alonso, Dario Antolin-Amerigo, Eloina González-Mancebo, Cristina Martin Garcia, Beatriz Nuñez-Acevedo, Nieves Prior, Marta Reche, Ana Rosado, Javier Ruiz-Hornillos, María Cesárea Sánchez, Miguel Torrecillas
The prevalence of sensitisation to dogs and cats varies by country, exposure time and predisposition to atopy. It is estimated that, 26% of European adults coming to the clinic for suspected allergy to inhalant allergens are sensitised to cats and 27% to dogs. This document is intended to be a useful tool for clinicians involved in the management of people with dog or cat allergy. It was prepared from a consensus process based on the RAND/UCLA method. Following a literature review, it proposes various recommendations concerning the diagnosis and treatment of these patients, grounded in evidence and clinical experience...
January 10, 2018: Allergy
https://www.readbyqxmd.com/read/29315948/a-patient-specific-approach-to-developing-an-exclusion-diet-to-manage-food-allergy-in-infants-and-children
#12
Carina Venter, Marion Groetch, Merryn Netting, Rosan Meyer
Food allergy is becoming increasingly common in infants and young children. This paper set out to explain the different factors that should be taken into account during an individualized allergy consultation: Foods to avoid and degree of avoidance, suitable alternatives, self-management skills, co-and cross-reactive allergens and novel allergens alongside the role of the industry in allergen avoidance, importance of nutritional aspects of the diet and the future directions that nutritional guidance make take...
January 8, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29314223/delayed-type-hypersensitivity-to-vaccine-aluminum-adjuvant-causing-subcutaneous-leg-mass-and-urticaria-in-a-child
#13
Samantha C Gordon, Diana W Bartenstein, Shahein H Tajmir, Johanna S Song, Elena B Hawryluk
A 3-year-old girl presented with a 7-month history of a waxing and waning left thigh mass associated with pruritus and erythema at the site of two previous DTaP-HepB-IPV vaccinations. Patch testing was positive to aluminum chloride, supporting a diagnosis of vaccine granuloma secondary to aluminum allergy; her symptoms had been well controlled with antihistamines and topical steroids. Injection site granulomas are a benign but potentially bothersome reaction to aluminum-containing immunizations that can be supportively managed, and we encourage strict adherence to the recommended vaccine schedule in this setting...
January 4, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29304914/evaluation-and-management-of-penicillin-allergy
#14
REVIEW
Thanai Pongdee, James T Li
Penicillin allergy is the most commonly reported drug allergy in the United States. Although penicillin allergy is widely reported, 80% to 90% of individuals with self-reported penicillin allergy are actually able to tolerate penicillins after undergoing evaluation for penicillin allergy. Because most patients with self-reported penicillin allergy will have subsequent negative allergy testing results and tolerate penicillins, they may be unnecessarily exposed to broader-spectrum antibiotics. Use of such antibiotics leads to increased risks of developing antibiotic-resistant microorganisms and incur higher health care utilization costs...
January 2018: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29303278/-asthma-bronchiale-in-the-context-of-internal-medicine
#15
Milan Teřl
The article is supposed to give a modern perspective on etiopatogenesis of asthma and its management. There are accentuated new diagnostics and treatment opportunities as well as coincident areas with others internal fields and pragmatic recommendation for daily clinical practice.Key words: allergy - asthma heterogeneity - asthma management - eosinophilia - internal medicine - phenotype-specific therapy - stepwise pharmacotherapy.
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29301119/cause-and-clinical-presentation-of-anaphylaxis-in-singapore-from-infancy-to-old-age
#16
Si Hui Goh, Jian Yi Soh, Wenyin Loh, Khai Pin Lee, Sze Chin Tan, Wei Jian Kenneth Heng, Irwani Ibrahim, Bee Wah Lee, Wen Chin Chiang
BACKGROUND: The study objective was to compare age-related differences in the cause and clinical presentation of anaphylaxis. METHODS: We conducted a prospective study of patients visiting the emergency department for anaphylaxis. Data were collected from 3 emergency departments from 1 April 2014 to 31 December 2015. Patient electronic records with the diagnoses of allergy, angioedema, urticaria, and anaphylaxis (ICD-9 codes 9953, 9951, 7080, 9950, 7089) were screened and cases fulfilling World Allergy Organisation criteria for anaphylaxis were included...
January 5, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29284253/risk-factors-for-work-related-eczema-and-urticaria-among-vocational-students-of-agriculture
#17
Radosław Śpiewak, Anna Góra-Florek, Andrzej Horoch, Mirosław J Jarosz, Agnieszka Doryńska, Marcin Golec, Jacek Dutkiewicz
INTRODUCTION AND OBJECTIVE: Farmers are at high risk of occupational skin diseases which may start already during vocational training. This study was aimed at identification of risk factors for work-related skin diseases among vocational students of agriculture. MATERIAL AND METHODS: The study involved 440 students (245 males, 195 females aged 17-21 years) in 11 vocational schools which were at least 100 km from each other. The protocol included a physician-managed questionnaire and medical examination, skin prick tests, patch tests, total IgE and Phadiatop...
December 23, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/29279057/characterizing-patients-with-asthma-who-received-global-initiative-for-asthma-steps-4-5-therapy-and-managed-in-a-specialty-care-setting
#18
Brian Stone, Jill R Davis, Frank Trudo, Bradd Schiffman, Carlos Alzola, David Brown, Kathleen M Fox
BACKGROUND: Severe asthma is recognized in the European Respiratory Society/American Thoracic Society guidelines as a major unmet need in the management of asthma. OBJECTIVE: The study objective was to describe the clinical burden of Global Initiative for Asthma (GINA) steps 4-5 asthma for patients treated by specialists in the U.S. community setting. METHODS: Patients, ages ≥12 years, with asthma who received GINA step 4 or 5 treatment and were treated at a large U...
January 1, 2018: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/29279054/the-dilemma-of-allergy-to-food-additives
#19
Sami L Bahna, Joshua G Burkhardt
OBJECTIVE: To provide a brief summary on food additives and to outline a practical approach for evaluating subjects suspected of having reactions to food additives. DATA SOURCES: Information was derived from selected reviews and original articles published in peer-reviewed journals, supplemented by the clinical experience of the authors. STUDY SELECTION: Priority was given to studies that used blinded, placebo controlled, oral challenges to confirm adverse reactions to food additives...
January 1, 2018: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/29277095/management-and-educational-status-of-adult-anaphylaxis-patients-at-emergency-department
#20
Mi-Yeong Kim, Chan Sun Park, Jae-Won Jeong
Background/Aims: We evaluated the management and educational status of adult anaphylaxis patients at emergency departments (EDs). Methods: Anaphylaxis patients who visited ED from 2011 to 2013 were enrolled from three hospitals. We analyzed clinical features, prior history of anaphylaxis, management and provided education for etiology and/or prevention. For analyzing associated factors with epinephrine injection, Pearson chi-square test was used by SPSS version 21 (IBM Co...
December 28, 2017: Korean Journal of Internal Medicine
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