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https://www.readbyqxmd.com/read/28630794/a-case-of-presumed-tuberculosis-uveitis-with-occlusive-vasculitis-from-an-endemic-region
#1
Berna Başarır, Yalçın Karaküçük, Çiğdem Altan, Banu Şatana, Bulut Ocak, Aslı İnal
In this report, we present a case with presumed unilateral tuberculosis uveitis from an endemic region. A 23-year-old male presented with decreased vision in his left eye for 15 days. Visual acuities were 1.0 in his right eye and 0.3 in his left eye. Ophthalmologic examination was normal for the right eye. Slit-lamp examination revealed 2+ cells in the vitreous without anterior chamber reaction in his left eye. Fundus examination revealed occlusive vasculitis and granuloma. His history revealed that he had a respiratory infection with fever 3 months ago while visiting his native country, Rwanda, and was treated with non-specific antibiotic therapy...
June 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28630792/corneal-collagen-crosslinking-treatment-in-a-case-with-pneumococcal-keratitis
#2
Ayşe Bozkurt Oflaz, Banu Bozkurt, Ümit Kamış, Bengü Ekinci Köktekir
Bacterial keratitis is a serious ocular infectious disease that can threaten vision. The disease generally progresses rapidly and can lead to corneal scar, stromal abscess formation, perforation, and dissemination to adjacent tissues if not treated properly. Recent studies showed that corneal collagen crosslinking (CCC) using ultraviolet-A/riboflavin is effective in the treatment of bacterial keratitis refractory to topical antibiotic treatment. In addition to being bactericidal, CCC also decreases risk of perforation by strengthening the corneal collagen structure...
June 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28628952/seeking-comfort-in-an-uncomfortable-chair
#3
Elena Molinari
The author explores the concept of comfort in relation to the setting. The concept of comfort, an unusual word in the psychoanalytic lexicon, describes the intuitive and complex experience of patient and analyst being together in the analytic office. The couch and the chair are not the only tools of the setting, but they are potential instruments with which to study the therapeutic process, both in high-frequency therapy and in lower-frequency treatments. To describe the transformations that an alternative experience of comfort can promote, the author looks at the intersection of this concept with the body-mind relationship and with the Bionian concept of binocular vision...
April 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/28624167/longitudinal-vision-related-quality-of-life-for-patients-with-noninfectious-uveitis-treated-with-fluocinolone-acetonide-implant-or-systemic-corticosteroid-therapy
#4
Elizabeth A Sugar, Vidya Venugopal, Jennifer E Thorne, Kevin D Frick, Gary N Holland, Robert C Wang, Robert Almanzor, Douglas A Jabs, Janet T Holbrook
PURPOSE: To evaluate longitudinal vision-related quality of life (VRQoL) in patients with noninfectious uveitis. DESIGN: Cohort study using randomized controlled trial data. PARTICIPANTS: Patients with active or recently active intermediate uveitis, posterior uveitis, or panuveitis enrolled in the Multicenter Steroid Treatment Trial and Follow-up Study. METHODS: Data from the 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) for the first 3 years after randomization were evaluated semiannually...
June 14, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28623785/in-vitro-studies-on-nobiletin-isolated-from-citrus-plants-and-the-bioactive-metabolites-inhibitory-action-against-gelatinase-enzymatic-activity-and-the-molecular-mechanisms-in-human-retinal-m%C3%A3-ller-cell-line
#5
Yoshiki Miyata, Terumasa Nagase, Yoshiya Katsura, Hideyo Takahashi, Hideaki Natsugari, Tetsuta Oshitari, Hiroshi Kosano
Diabetic retinopathy (DR) is the most common cause of vision loss in patients with diabetes mellitus. Despite the presence of effective therapy, DR is still a significant health burden. A recent research suggests that matrix metalloproteinases (MMPs) could be promising targets, which exert multiple actions on early- and late-stage pathogenesis of DR. Among the MMP family, gelatinases (MMP-2 and MMP-9) act as potent proinflammatory, proangiogenic, and pro-apoptotic factors. Therefore, the pharmacological inhibitory effect of gelatinases on retinal MMP-producing cells may be useful in the treatment or prevention of DR...
June 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28622321/identification-of-time-point-to-best-define-sub-optimal-response-following-intravitreal-ranibizumab-therapy-for-diabetic-macular-edema-based-on-real-life-data
#6
I Chatziralli, M Santarelli, N Patrao, L Nicholson, M Zola, R Rajendram, P Hykin, S Sivaprasad
PurposeTo determine the average time-point at which it is best to define 'sub-optimal response' after ranibizumab treatment for diabetic macular edema (DME) based on the data obtained from real-life clinical practice.MethodsIn this retrospective observational study, 322 consecutive treatment naïve eyes with DME were treated with three loading doses of intravitreal ranibizumab followed by re-treatment based on decision of the treating physician on a case-by-case basis. The demographic data, clinic-based visual acuity measurements and central subfield thickness (CST) assessed on spectral domain optical coherence tomography (OCT) were evaluated at baseline (month 0), 1, 2, 3, 6, and 12 months...
June 16, 2017: Eye
https://www.readbyqxmd.com/read/28621715/neuropsychiatric-burden-in-huntington-s-disease
#7
REVIEW
Ricardo Augusto Paoli, Andrea Botturi, Andrea Ciammola, Vincenzo Silani, Cecilia Prunas, Claudio Lucchiari, Elisa Zugno, Elisabetta Caletti
Huntington's disease is a disorder that results in motor, cognitive, and psychiatric problems. The symptoms often take different forms and the presence of disturbances of the psychic sphere reduces patients' autonomy and quality of life, also impacting patients' social life. It is estimated that a prevalence between 33% and 76% of the main psychiatric syndromes may arise in different phases of the disease, often in atypical form, even 20 years before the onset of chorea and dementia. We present a narrative review of the literature describing the main psychopathological patterns that may be found in Huntington's disease, searching for a related article in the main database sources (Medline, ISI Web of Knowledge, Scopus, and Medscape)...
June 16, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28620731/retinoblastoma
#8
Raksha Rao, Santosh G Honavar
Retinoblastoma represents 3% of all childhood cancers, and is the most common intraocular malignancy of childhood. It is fatal, if untreated. White eye reflex, also known as leukocoria, is the commonest sign, followed by strabismus. The pediatricians have a very important role to play in the diagnosis of this relatively rare, but easily detectable tumor. Early diagnosis yields better results. The management of retinoblastoma has gradually evolved over the past few decades, with an aim to not only preserve life and eye, but also optimize residual vision...
June 16, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28619977/infectious-crystalline-keratopathy-after-descemet%C3%A3-%C3%A2-%C3%A2-s-stripping-endothelial-keratoplasty
#9
Ashley J Porter, Graham A Lee, Kevin Whitehead
A 68-year-old woman presented with infectious crystalline keratopathy 4 months after she underwent a combined phacoemulsification and Descemet's stripping endothelial keratoplasty for Fuch's endothelial dystrophy in her left eye. After 5 months of topical moxifloxacin 1%, the infiltrate responded well but had not completely resolved, with the resulting endothelial failure requiring a penetrating keratoplasty 9 months after the initial operation. Microbiology identified Enterococcus faecalis with the histopathology demonstrating bacterial colonies within the graft interface...
June 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28616359/bioactive-antimicrobial-peptides-as-therapeutics-for-corneal-wounds-and-infections
#10
REVIEW
Gina L Griffith, Anne Kasus-Jacobi, H Anne Pereira
Significance: More than 2 million eye injuries and infections occur each year in the United States that leave civilians and military members with reduced or complete vision loss due to the lack of effective therapeutics. Severe ocular injuries and infections occur in varied settings including the home, workplace, and battlefields. In this review, we discuss the potential of developing antimicrobial peptides (AMPs) as therapeutics for the treatment of corneal wounds and infections for which the current treatment options are inadequate...
June 1, 2017: Advances in Wound Care
https://www.readbyqxmd.com/read/28615856/a-rare-case-of-theileria-annulata-induced-corneal-opacity-in-a-calf
#11
Vivek Joshi, S Alam, U Dimri, A G Bhanuprakash, A Gopalakrishnan, Y Ajith
A 10 months old male cross-bred calf was presented in OPD Medicine, Referral Veterinary Polyclinic, ICAR-Indian Veterinary Research Institute, Izatnagar with the history of anorexia, impaired vision, heavy tick infestation and diarrhoea for the last 1 week. The clinical examination revealed enlarged pre-scapular lymph nodes, prominent cloudiness in eyes and exophthalmos. The presence of Koch blue bodies in biopsied lymph nodes and a PCR assay confirmed it to be bovine tropical theileriosis associated with unique corneal opacity...
June 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28615794/deepinfer-open-source-deep-learning-deployment-toolkit-for-image-guided-therapy
#12
Alireza Mehrtash, Mehran Pesteie, Jorden Hetherington, Peter A Behringer, Tina Kapur, William M Wells, Robert Rohling, Andriy Fedorov, Purang Abolmaesumi
Deep learning models have outperformed some of the previous state-of-the-art approaches in medical image analysis. Instead of using hand-engineered features, deep models attempt to automatically extract hierarchical representations at multiple levels of abstraction from the data. Therefore, deep models are usually considered to be more flexible and robust solutions for image analysis problems compared to conventional computer vision models. They have demonstrated significant improvements in computer-aided diagnosis and automatic medical image analysis applied to such tasks as image segmentation, classification and registration...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28614556/binocular-therapy-for-childhood-amblyopia-improves-vision-without-breaking-interocular-suppression
#13
Manuela Bossi, Vijay K Tailor, Elaine J Anderson, Peter J Bex, John A Greenwood, Annegret Dahlmann-Noor, Steven C Dakin
Purpose: Amblyopia is a common developmental visual impairment characterized by a substantial difference in acuity between the two eyes. Current monocular treatments, which promote use of the affected eye by occluding or blurring the fellow eye, improve acuity, but are hindered by poor compliance. Recently developed binocular treatments can produce rapid gains in visual function, thought to be as a result of reduced interocular suppression. We set out to develop an effective home-based binocular treatment system for amblyopia that would engage high levels of compliance but that would also allow us to assess the role of suppression in children's response to binocular treatment...
June 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28611623/visual-loss-induced-by-adalimumab-used-for-plaque-psoriasis
#14
Norman Saffra, Konstantin Astafurov
A 61-year-old Caucasian male with severe plaque psoriasis without joint involvement was initiated on adalimumab therapy. Shortly thereafter he presented to the emergency room with acute loss of vision in the right eye. A comprehensive systemic workup was instituted which included magnetic resonance imaging (MRI) with and without gadolinium of the brain and orbits. MRI revealed findings that were consistent with CNS demyelination and retrobulbar optic neuritis. Immediate cessation of adalimumab was instituted without any other systemic therapy...
January 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/28608150/-arthroscopy-of-the-proximal-interphalangeal-joint
#15
N Borisch
OBJECTIVE: Pain reduction in the affected proximal interphalangeal joint (PIP joint) by synovectomy, loose body extraction, dorsal arthrolysis. INDICATIONS: Therapy-resistant synovitis in rheumatoid arthritis (RA), early stage primary and secondary degenerative arthritis, loose bodies, capsular contracture. CONTRAINDICATIONS: Established biomechanic changes in RA (boutonniere and swanneck deformity). Large dorsal synovial cysts. Advanced radiologic changes in degenerative arthritis...
June 12, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28606271/-bone-marrow-derived-fibrocytes-and-thyroid-associated-opthalmopathy
#16
T Wu, D R Tang, F Y Sun
Thyroid-associated opthalmopathy(TAO) is a common autoimmune syndrome affecting the thyroid and orbit, which can result in the fibrosis of extraoular muscles and hyperplasia of adipose tissue. Advanced TAO patients could even lose vision caused by cornea ulcer and congestion of optic nerve from expansion of the extraocular muscles and orbit fat. Currently, there are no therapies shown to prevent it, because its cellular and molecular mechanisms are not clear. Some studies have recently implicated bone marrow-derived fibroblast-like, called fibrocytes are involved in the pathogenesis of TAO...
June 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28606262/-therapeutic-outcomes-and-influence-factors-of-maximal-orbital-decompression-in-the-treatment-of-severe-dysthyroid-optic-neuropathy
#17
Y Wang, Y Y Li, N Yang, R Ma, L H Xiao
Objective: To evaluate the effectiveness of maximal orbital decompression in treatment for severe dysthyroid optic neuropathy (DON) of thyroid associated ophthalmopathy (TAO) and predictive factors of this therapy. Methods: The group consisted of 21 patients (30 eyes) with DON. The diagnosis was based on the following criteria: Deterioration of best corrected visual acuity (VA≤0.1), enlargement of extraocular muscles and sign of apical crowding in CT imaging, loss of colour vision. EXCLUSION CRITERIA: VA of DON>0...
June 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28604324/cytomegalovirus-retinitis-in-cape-town-south-africa-clinical-management-and-outcomes
#18
Steven R J Lapere, James C Rice
BACKGROUND: Cytomegalovirus (CMV) retinitis is a vision-threatening opportunistic infection that occurs mainly in immunocompromised individuals. Limited data on treatment protocols and management outcomes are available in South Africa (SA). OBJECTIVES: To review the clinical presentation, management and outcomes of patients who were diagnosed and treated for CMV retinitis at Groote Schuur Hospital, Cape Town, SA, over a 10-year period, and to compare treatment protocols of 13 public hospitals in SA that treat patients for CMV retinitis...
May 24, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28602322/trabecular-microbypass-stent-implantation-with-cataract-extraction-in%C3%A2-pseudoexfoliation-glaucoma
#19
Tanner J Ferguson, Russell Swan, Mitch Ibach, Justin Schweitzer, Ramu Sudhagoni, John P Berdahl
PURPOSE: To evaluate the safety and efficacy of a trabecular microbypass stent (iStent) combined with cataract surgery in patients with pseudoexfoliation glaucoma (PXG). SETTING: Vance Thompson Vision, Sioux Falls, South Dakota, USA. DESIGN: Retrospective case series. METHODS: Eyes with PXG had implantation of 1 stent. Data were collected preoperatively and postoperatively through 24 months. Data included intraocular pressure (IOP), number of glaucoma medications, the incidence of postoperative IOP pressure spikes of 15 mm Hg or higher at any timepoint, and the need for additional surgery...
May 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28599912/efficacy-of-vision-therapy-in-children-with-learning-disability-and-associated-binocular-vision-anomalies
#20
Jameel Rizwana Hussaindeen, Prerana Shah, Krishna Kumar Ramani, Lalitha Ramanujan
PURPOSE: To report the frequency of binocular vision (BV) anomalies in children with specific learning disorders (SLD) and to assess the efficacy of vision therapy (VT) in children with a non-strabismic binocular vision anomaly (NSBVA). METHODS: The study was carried out at a centre for learning disability (LD). Comprehensive eye examination and binocular vision assessment was carried out for 94 children (mean (SD) age: 15 (2.2) years) diagnosed with specific learning disorder...
June 6, 2017: Journal of Optometry
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