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Gallstones Disease

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https://www.readbyqxmd.com/read/28433486/gallstone-ileus-an-overview-of-the-literature
#1
C F Ploneda-Valencia, M Gallo-Morales, C Rinchon, E Navarro-Muñiz, C A Bautista-López, L F de la Cerda-Trujillo, L A Rea-Azpeitia, C R López-Lizarraga
INTRODUCTION: Gallstone ileus represents 4% of the causes of bowel obstruction in the general population, but increases to 25% in patients above the age of 65 years. Gallstone ileus does not present with unique symptoms, making diagnosis difficult. Its management is surgical, but there is no consensus as to which of the different surgical techniques is the procedure of choice. At present, there is no recent review of this pathology. AIM: To conduct an up-to-date review of this disease...
April 19, 2017: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/28412956/management-of-suspected-common-bile-duct-stones-on-cholangiogram-during-same-stay-cholecystectomy-for-acute-gallstone-related-disease
#2
Sandra de Sousa, Olivier Tobler, Pouya Iranmanesh, Jean-Louis Frossard, Philippe Morel, Christian Toso
BACKGROUND: Recent data have suggested that upfront cholecystectomy should be performed even in the presence of moderately abnormal liver function tests (LFTs). As a consequence, more common bile duct (CBD) stones are discovered on intra-operative cholangiogram. We assessed the presentation and management of such patients to refine their management plan. METHODS: Adult patients (>16 years) with an acute gallstone-related disease who had undergone same-stay cholecystectomy from January 2013 to January 2015 were retrospectively assessed...
April 17, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28409371/dynamic-analysis-of-commonly-used-biochemical-parameters-to-predict-common-bile-duct-stones-in-patients-undergoing-laparoscopic-cholecystectomy
#3
Stéphane Bourgouin, Xavier Truchet, Gatien Lamblin, Jérôme De Roulhac, Jean-Philippe Platel, Paul Balandraud
BACKGROUND: The prediction of persistent common bile duct stones (CBDS) in patients during choledocholithiasis crisis is challenging. We developed a model based on the course over time of commonly used biochemical parameters to reduce the rate of unnecessary endoscopic cholangiopancreatography (ERCP) and the risk of perioperative discovery of CBDS. METHODS: Medical charts of patients who presented between 2010 and 2015 for symptomatic gallstone disease with suspected choledocholithiasis were reviewed and compared according to the presence/absence of CBDS on preoperative ERCP or during cholecystectomy...
April 13, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28403124/association-between-oral-hygiene-and-ultrasound-confirmed-gallstone-disease-in-us-population
#4
Sanjay Bhandari, Madhavi Reddy, Ghulamullah Shahzad
No abstract text is available yet for this article.
April 11, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28401880/gallstone-ileus-a-case-treated-with-minilaparotomy-and-a-review-of-the-literature
#5
Francesco Zappia, Giovanni Petracca, Carlo Alessandro Talarico
Gallstone ileus is a rare complication of cholelithiasis which occurs in less than 1% of patients and is the cause of 1- 4% of cases of small bowel obstruction. The pathogenesis involves the formation of a bilioenteric fistula. We report the case of gallstone ileus in an 81-year old woman with typical abdominal pain, arterial hypertension and coronary artery disease. An abdominal computed tomography (CT) scan showed pneumobilia, dilated loops of small bowel and an ectopic gallstone obstructing the intestinal lumen...
March 29, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28401383/gallstone-disease-after-laparoscopic-sleeve-gastrectomy-in-an-asian-population-what-proportion-of-gallstones-actually-becomes-symptomatic
#6
Muhammed Yaser Hasan, Davide Lomanto, Lee Leng Loh, Jimmy Bok Yan So, Asim Shabbir
BACKGROUND: Despite evidence on gallstone disease after laparoscopic sleeve gastrectomy (LSG), there is an existing lack of consensus on practice guidelines, i.e., surveillance and stone-lowering prophylaxis. Available evidence also has a racial bias as western reports predominate current data. Considering the growing popularity of LSG in Asia and the unique Asian anthropometrics, we have attempted to provide a regional perspective by reviewing our LSG database to investigate the epidemiology of this complication...
April 11, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28400123/predictors-of-incidental-gallbladder-cancer-in-patients-undergoing-cholecystectomy-for-benign-gallbladder-disease-results-from-a-population-based-gallstone-surgery-registry
#7
Carolina Muszynska, Linda Lundgren, Gert Lindell, Roland Andersson, Johan Nilsson, Per Sandström, Bodil Andersson
BACKGROUND: Gallbladder cancer is a rare neoplasm with a poor prognosis. Early diagnosis and correct treatment strategy is important. The aim of this study was to identify predictors for incidental gallbladder cancer. METHODS: Data from cholecystectomies registered in the nationwide Swedish Register for Gallstone Surgery between 2007 and 2014 were analyzed for incidental gallbladder cancer. Exclusion criteria were patients with a gallbladder not sent for histopathology, preoperative suspicion of polyps/gallbladder cancer, and indication for operation for other reasons than gallstone disease...
April 8, 2017: Surgery
https://www.readbyqxmd.com/read/28396133/recurre-of-gallstone-disease-following-non-surgical-treatment-of-acute-cholecystitis-in-the-elderly-population
#8
Ismael Mora-Guzmán, Marcello Di Martino, Elena Martín-Pérez
No abstract text is available yet for this article.
April 8, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28385120/are-routine-preoperative-liver-function-tests-in-patients-with-uncomplicated-symptomatic-gallstone-disease-necessary
#9
Marijke van den Berg, Gijs M van Couwelaar, Christel A L de Raaff, Sjoerd M Lagarde, Pieter Joosse, Bart A van Wagensveld, Bart C Vrouenraets
BACKGROUND: The aim of this study was to evaluate the value of preoperative liver function tests (LFTs) in patients with uncomplicated gallstone disease and scheduled for laparoscopic cholecystectomy. METHODS: All 1112 patients who underwent a laparoscopic cholecystectomy for symptomatic gallstone disease during a 6-year cohort were retrospectively reviewed. Only patients who presented with uncomplicated disease were selected. Preoperative LFTs, pre-, and postoperative endoscopic retrograde cholangio pancreaticographies (ERCPs) and postoperative complications were collected...
April 7, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28377802/an-observational-study-on-the-association-of-nonalcoholic-fatty-liver-disease-and-metabolic-syndrome-with-gall-stone-disease-requiring-cholecystectomy
#10
Farah Ahmed, Qamaruddin Baloch, Zahid Ali Memon, Iqra Ali
OBJECTIVE: Recognition of Non alcoholic fatty liver disease (NAFLD) and metabolic syndrome in patients with gallstones undergoing laparoscopic or open cholecystectomy, along with it we will also study the life style of patients with gall stones. BACKGROUND: Patients with gallstones have associated NAFLD, with concurrent metabolic syndrome and these ailments share similar factors for example obesity, hypertriglyceridemia and diabetes mellitus. Factors like body mass index, gender, raised lipid levels, use of contraceptives and alcohol and having diabetes, physical inactiveness, multiparous women, water with excessive iron content, metabolic syndrome, and NAFLD are accountable factors for gallstones formation...
May 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28376203/coffee-consumption-and-risk-of-gallbladder-cancer-in-a-prospective-study
#11
Susanna C Larsson, Edward L Giovannucci, Alicja Wolk
Evidence indicates that coffee consumption may reduce the risk of gallstone disease, which is strongly associated with increased risk of gallbladder cancer. The association between coffee consumption and gallbladder cancer incidence was examined in a prospective cohort study of 72 680 Swedish adults (aged 45 - 83 years) who were free of cancer and reported their coffee consumption at baseline. Gallbladder cancers were ascertained by linkage with the Swedish Cancer Register. The data were analyzed using Cox proportional hazards regression models...
March 1, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28364324/primary-hyperparathyroidism-insights-from-the-indian-phpt-registry
#12
Sanjay Kumar Bhadada, Ashutosh Kumar Arya, Satinath Mukhopadhyay, Rajesh Khadgawat, Suja Sukumar, Sailesh Lodha, Deependra N Singh, Anjali Sathya, Priyanka Singh, Anil Bhansali
The presentation of primary hyperparathyroidism (PHPT) is variable throughout the world. The present study explored retrospective data submitted to the Indian PHPT registry ( http://www.indianphptregistry.com ) between July 2005 and June 2015 from 5 centres covering four different geographical regions. The clinical, biochemical, radiological and histopathological characteristics of PHPT patients across India were analysed for similarity and variability across the centres. A total of 464 subjects (137 men and 327 women) with histopathologically proven PHPT were analysed...
March 31, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/28359408/robotic-versus-conventional-laparoscopic-cholecystectomy-a-comparative-study-of-medical-resource-utilization-and-clinical-outcomes
#13
Yu-Pei Li, Shen-Nien Wang, King-Teh Lee
Conventional laparoscopic cholecystectomy (CLC) is currently the standard of surgical procedure for gallstone disease. Robotic cholecystectomy (RC) has revolutionized the field of minimally invasive surgery; it is safe and ergonomic, but expensive. The aim of this study is to compare the medical resource utilization and clinical outcomes between the two procedures. This study was conducted retrospectively by assessing data of the clinical outcomes and medical resource of 78 patients receiving RC and 367 patients receiving CLC...
April 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28355987/acute-acalculous-cholecystitis-in-patients-with-systemic-lupus-erythematosus-a-unique-form-of-disease-flare
#14
H Yang, S Bian, D Xu, F Zhang, X Zhang
Objective We aimed to investigate the clinical features of acute acalculous cholecystitis (AAC) in patients with systemic lupus erythematosus (SLE). Methods SLE patients with AAC hospitalized in the Peking Union Medical College Hospital (PUMCH) from January 2001 to September 2015 were retrospectively analyzed. Their medical records were systematically reviewed. The diagnosis of AAC was based on clinical manifestations and confirmed by radiologic findings including a distended gallbladder with thickened wall, pericholecystic fluid and absence of gallstones...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28343425/ppar-%C3%AE-agonists-are-still-on-the-rise-an-update-on-clinical-and-experimental-findings
#15
Nicola Ferri, Alberto Corsini, Cesare Sirtori, Massimiliano Ruscica
Non-fasting plasma triglyceride (TG) and remnant cholesterol levels, cholesterol content of triglyceride-rich lipoproteins, have been suggested to be an additional cause of cardiovascular diseases; thus, pharmacological TG-lowering with fibrates, activators of PPAR-alpha system, has been linked to risk reduction. Areas covered: This manuscript reviews available evidence on clinical trials involving highly selective PPAR-α agonists (i.e., pemafibrate) and drugs used in the pre-clinical and experimental setting (e...
May 2017: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/28336180/an-important-intestinal-transporter-that-regulates-the-enterohepatic-circulation-of-bile-acids-and-cholesterol-homeostasis-the-apical-sodium-dependent-bile-acid-transporter-slc10a2-asbt
#16
Ling Xiao, Guoyu Pan
The enterohepatic circulation of bile acids (BAs) is governed by specific transporters expressed in the liver and the intestine and plays a critical role in the digestion of fats and oils. During this process, the majority of the BAs secreted from the liver is reabsorbed in intestinal epithelial cells via the apical sodium-dependent bile acid transporter (ASBT/SLC10A2) and then transported into the portal vein. Previous studies revealed that regulation of the ASBT involves BAs and cholesterol. In addition, abnormal ASBT expression and function might lead to some diseases associated with disorders in the enterohepatic circulation of BAs and cholesterol homeostasis, such as diarrhoea and gallstones...
March 20, 2017: Clinics and Research in Hepatology and Gastroenterology
https://www.readbyqxmd.com/read/28331267/laparoscopic-management-of-a-proximal-jejunal-gallstone-ileus-with-patulous-ampulla-and-choledochal-cyst-a-report-of-unusual-presentation-and-a-review
#17
REVIEW
Rajvilas Anil Narkhede, Vijaykumar C Bada, Lakshmi Kumari Kona
Gallstone ileus is a diagnosis of rarity, and a proximal site of obstruction in a young patient is even rare. Of the three cases in our experience, we found two cases of gallstone ileus (GSI) with typical epidemiology and presentation, one had combination of multiple rare associations. We report such a case, suspected to have gallstone ileus on ultrasound and confirmed diagnosis on computed tomography. Presence of biliary-enteric fistula, old age, and obstructive features, as in typical cases, was a bigger asset for diagnosis, but it was difficult to entertain diagnosis of GSI in young girl in absence of a demonstrable biliary-enteric fistula, with uncommon association of choledochal cyst and sickle cell disease...
February 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28324273/acute-pancreatitis-caused-by-mycoplasma-pneumoniae-an-unusual-etiology
#18
Teresa Valdés Lacasa, María Alejandra Duarte Borges, Alicia García Marín, Covadonga Gómez Cuervo
It is well known that the most important etiologies of acute pancreatitis are gallstones and alcohol consumption. Once these causes have been ruled out, especially in young adults, it is important to consider less frequent etiologic factors such as drugs, trauma, malformations, autoimmunity or systemic diseases. Other rare and less well studied causes of this pathology are infections, among which Mycoplasma pneumoniae has been reported to cause acute pancreatitis as an unusual extrapulmonary manifestation. Here, we report the case of a 21-year-old patient who had acute idiopathic pancreatitis associated with an upper respiratory tract infection...
March 21, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28321066/gilbert-syndrome-with-concomitant-hereditary-spherocytosis-presenting-with-moderate-unconjugated-hyperbilirubinemia
#19
Mitsuhiko Aiso, Minami Yagi, Atsushi Tanaka, Kotaro Miura, Ryo Miura, Toshihiko Arizumi, Yoriyuki Takamori, Sayuri Nakahara, Yoshihiro Maruo, Hajime Takikawa
We experienced a case of a 19-year-old man with Gilbert syndrome with concomitant hereditary spherocytosis. The patient presented with moderate unconjugated hyperbilirubinemia, and inherited etiology was strongly suspected. The diagnosis of Gilbert syndrome was confirmed by the genetic analysis of the UGT1A1 gene, demonstrating UGT1A1*28 and compound heterozygote UGT1A1*6. In addition, since the laboratory findings and imaging studies revealed lysemia as well as gallstone and splenomegaly, a diagnosis of hereditary spherocytosis was made as a comorbidity...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28301778/risk-stratified-versus-non-risk-stratified-diagnostic-testing-for-management-of-suspected-acute-biliary-obstruction-comparative-effectiveness-costs-and-the-role-of-mr-cholangiopancreatography
#20
Stella K Kang, David Hoffman, Bart Ferket, Michelle I Kim, R Scott Braithwaite
Purpose To analyze the cost effectiveness of the American Society for Gastrointestinal Endoscopy (ASGE) risk stratification guidelines versus magnetic resonance (MR) cholangiopancreatography-based treatment of patients with possible choledocholithiasis. Materials and Methods A decision-analytic model was constructed to compare cost and effectiveness of three diagnostic strategies for gallstone disease with possible choledocholithiasis: noncontrast MR cholangiopancreatography, contrast material-enhanced MR imaging/MR cholangiopancreatography, and ASGE risk stratification guidelines for diagnostic evaluation recommending endoscopy (high risk), MR cholangiopancreatography (intermediate risk), or no test (low risk)...
March 16, 2017: Radiology
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