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https://www.readbyqxmd.com/read/29331563/trends-in-premature-mortality-due-to-heart-failure-by-autonomous-community-in-spain-1999-to-2013
#1
Lidia Gómez-Martínez, Domingo Orozco-Beltrán, José A Quesada, Vicente Bertomeu-González, Vicente F Gil-Guillén, Adriana López-Pineda, Concepción Carratalá-Munuera
INTRODUCTION AND OBJECTIVES: Heart failure (HF) is a major public health problem, and the prevalence increases with age. In Spain, there are considerable differences between autonomous communities. The aim of this study was to analyze trends in premature mortality due to HF between 1999 and 2013 in Spain by autonomous community. METHODS: We analyzed data on mortality due to HF in Spanish residents aged 0 to 75 years by autonomous community between 1999 and 2013...
January 10, 2018: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29327756/isomeric-and-hybrid-ferrocenyl-cyrhetrenyl-aldimines-a-new-family-of-multifunctional-compounds
#2
Juan Oyarzo, Alejandra Acuña, Hugo Klahn, Rodrigo Arancibia, Carlos P Silva, Ramón Bosque, Concepción López, Mercè Font-Bardía, Carme Calvis, Ramón Messeguer
The synthesis and characterization of two novel and isomeric hybrid ferrocenyl/cyrhetrenyl aldimines [(η5-C5H5)Fe{(η5-C5H4)-CH[double bond, length as m-dash]N-(η5-C5H4)}Re(CO)3] (1) and [(η5-C5H5)Fe{(η5-C5H4)-N[double bond, length as m-dash]CH-(η5-C5H4)}Re(CO)3] (2) are reported. Their X-ray crystal structures reveal that both adopt the E form. However, molecules of 1 and 2 differ in the relative arrangement of the "Fe(η5-C5H5)" and "Re(CO)3" units (anti in 1 and syn in 2). This affects the type of intermolecular interactions, the assembly of the molecules and therefore their crystal architecture...
January 12, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29327322/molecular-characterization-of-avian-malaria-in-the-spotless-starling-sturnus-unicolor
#3
Jaime Muriel, Jeff A Graves, Diego Gil, S Magallanes, Concepción Salaberria, Miriam Casal-López, Alfonso Marzal
We studied the prevalence and genetic diversity of malaria parasites in the poorly investigated spotless starling (Sturnus unicolor) breeding in central Spain, aiming to describe the phylogenetic relationships among them and with other haemosporidians infecting the genus Sturnus. A total of 180 nestlings and 180 adult individuals from four different breeding seasons were screened for haemosporidian parasites using a nested PCR approach for the genera Plasmodium and Haemoproteus. Although the malaria prevalence ranged between years, the overall prevalence was 6...
January 11, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29319888/formation-of-cyanamide-glyoxal-oligomers-in-aqueous-environments-relevant-to-primeval-and-astrochemical-scenarios-a-spectroscopic-and-theoretical-study
#4
Nieves Lavado, Juan García de la Concepción, Reyes Babiano, Pedro Cintas
The condensation of cyanamide and glyoxal, two well-known prebiotic monomers, in aqueous phase has been investigated in great detail, demonstrating the formation of oligomeric species of varied structure, though consistent with generalizable patterns. This chemistry involving structurally simple substances also illustrates the ability of building molecular complexity under prebiotically plausible conditions, not only on Earth but also on extraterrestrial scenarios. We show that cyanamide-glyoxal reactions in water lead to mixtures comprising both acyclic and cyclic fragments, largely based on fused five- and six-membered rings, which can be predicted by computation...
January 10, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29318221/iga-dominant-acute-postinfectious-glomerulonephritis-presenting-as-acute-renal-failure-in-a-kidney-transplant-recipient
#5
Manish Anand, Juan Pablo Arroyo, Hassan Alhalabi, Timothy Thayer, Mark Lusco, Anthony Langone, Beatrice P Concepcion
No abstract text is available yet for this article.
July 2017: KI Reports
https://www.readbyqxmd.com/read/29314174/validation-of-eating-disorders-examination-questionnaire-in-mexican-women
#6
Claudia Unikel Santoncini, Ietza Bojorquez Chapela, Concepción Díaz de León Vázquez, Verónica Vázquez Velázquez, José Alberto Rivera Márquez, Griselda Galván Sánchez, Ingrid Rocha Velis
BACKGROUND: Efficient assessment of eating disorders (ED) is indispensable for research and clinical practice in Mexico. One of the most commonly used questionnaires, the EDE-Q, has a self-applicable questionnaire format with 28 questions and four subscales drawn from the Eating Disorder Examination (EDE), a semistructured interview developed to evaluate the specific symptomatology of eating disorders. OBJECTIVE: Obtain the factorial structure and construct validity of the EDE-Q questionnaire in Mexican women...
January 4, 2018: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29304092/dipeptidyl-peptidase-3-a-novel-protease-from-leishmania-braziliensis
#7
Jenny R Diaz, Cesar A Ramírez, Paola A Nocua, Fanny Guzman, José M Requena, Concepción J Puerta
The increase of leishmaniasis cases worldwide and the emergence of Leishmania strains resistant to current treatments make necessary to find new therapeutic targets. Proteases are appealing drug targets because they play pivotal roles in facilitating parasite survival and promoting pathogenesis. Enzymes belonging to the dipeptidyl peptidase 3 (DPP3) group have been described in different organisms such as mammals, insects and yeast, in which these enzymes have been involved in both protein turnover and protection against oxidative damage...
2018: PloS One
https://www.readbyqxmd.com/read/29302487/central-round-block-repair-of-large-breast-resection-defects-oncologic-and-aesthetic-outcomes
#8
Russell J Bramhall, Jason Lee, Mae Concepcion, David Westbroek, Sarah Huf, Kabir Mohammed, Paul Thiruchelvam, Gerald P Gui
Background: The central round block repair is a volume displacement technique to reconstruct large wide local excision (WLE) defects in breasts with moderate ptosis or hypertrophy. There are limited published data on the outcomes of this technique. Methods: Data were collected prospectively for 57 consecutive patients and follow up information obtained from patient records. The volume of breast resection was estimated geometrically from mammography. Aesthetic outcomes were assessed from clinical measurements and panel review of patient photographs...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29297822/early-onset-of-the-reproductive-season-in-captive-white-tailed-deer-odocoileus-virginianus-veraecrucis-in-eastern-mexico
#9
Concepción Ahuja-Aguirre, Omar Pérez-Gutiérrez, Lorena López-deBuen, Susana Rojas-Maya, Felipe Montiel-Palacios
The white-tailed deer ( Odocoileus virginianus) inhabits a wide latitudinal range in the Americas. Deer species dwelling throughout wide latitudinal ranges have developed subspecies with variations in their reproductive seasonality. In northern subspecies of white-tailed deer, such as those from Canada and the United States, the breeding season occurs from October through December. Odocoileus virginianus veraecrucis is a subspecies that inhabits eastern Mexico, and because its reproductive season has not been studied, it is believed to be similar to that from northern subspecies...
December 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29297135/stem-cell-factor-supports-migration-in-canine-mesenchymal-stem-cells
#10
Nathaly Enciso, Luciana L K Ostronoff, Guillermo Mejías, Leticia G León, María Luisa Fermín, Elena Merino, Cristina Fragio, Luis Avedillo, Concepción Tejero
Adult Mesenchymal Stem Cells (MSC) are cells that can be defined as multipotent cells able to differentiate into diverse lineages, under appropriate conditions. These cells have been widely used in regenerative medicine, both in preclinical and clinical settings. Initially discovered in bone marrow, MSC can now be isolated from a wide spectrum of adult and foetal tissues. Studies to evaluate the therapeutic potential of these cells are based on their ability to arrive to damaged tissues. In this paper we have done a comparative study analyzing proliferation, surface markers and OCT4, SOX9, RUNX2, PPARG genes expression in MSC cells from Bone marrow (BMMSC) and Adipose tissue (ASC)...
January 3, 2018: Veterinary Research Communications
https://www.readbyqxmd.com/read/29296834/haploidentical-transplant-in-patients-with-myelodysplastic-syndrome
#11
Marie Robin, Raphael Porcher, Fabio Ciceri, Maria Teresa van Lint, Stella Santarone, Gerhard Ehninger, Didier Blaise, Zafer Güllbas, Soledad Gonzáles Muñiz, Mauricette Michallet, Andrea Velardi, Linda Koster, Johan Maertens, Jorge Sierra, Dominik Selleslag, Aleksandar Radujkovic, José L Díez-Martin, Lothar Kanz, Concepcion Herrera Arroyo, Dietger Niederwieser, He Huang, Andrew McDonald, Theo de Witte, Yener Koc, Nicolaus Kröger
The only curative treatment in patients with intermediate or high-risk myelodysplastic syndrome (MDS) is allogeneic hematopoietic stem cell transplantation (HSCT), which usually results in a long-term, disease-free survival rate of between 30% and 50%, depending on the disease risk and the type of donor. In patients without an HLA-matched sibling donor, a family haploidentical donor is an alternative option. The present study reports the European Group for Blood and Marrow Transplantation activity for haploidentical transplantation in MDS patients...
October 10, 2017: Blood Advances
https://www.readbyqxmd.com/read/29290338/genotype-phenotype-correlation-in-nf1-evidence-for-a-more-severe-phenotype-associated-with-missense-mutations-affecting-nf1-codons-844-848
#12
Magdalena Koczkowska, Yunjia Chen, Tom Callens, Alicia Gomes, Angela Sharp, Sherrell Johnson, Meng-Chang Hsiao, Zhenbin Chen, Meena Balasubramanian, Christopher P Barnett, Troy A Becker, Shay Ben-Shachar, Debora R Bertola, Jaishri O Blakeley, Emma M M Burkitt-Wright, Alison Callaway, Melissa Crenshaw, Karin S Cunha, Mitch Cunningham, Maria D D'Agostino, Karin Dahan, Alessandro De Luca, Anne Destrée, Radhika Dhamija, Marica Eoli, D Gareth R Evans, Patricia Galvin-Parton, Jaya K George-Abraham, Karen W Gripp, Jose Guevara-Campos, Neil A Hanchard, Concepcion Hernández-Chico, LaDonna Immken, Sandra Janssens, Kristi J Jones, Beth A Keena, Aaina Kochhar, Jan Liebelt, Arelis Martir-Negron, Maurice J Mahoney, Isabelle Maystadt, Carey McDougall, Meriel McEntagart, Nancy Mendelsohn, David T Miller, Geert Mortier, Jenny Morton, John Pappas, Scott R Plotkin, Dinel Pond, Kenneth Rosenbaum, Karol Rubin, Laura Russell, Lane S Rutledge, Veronica Saletti, Rhonda Schonberg, Allison Schreiber, Meredith Seidel, Elizabeth Siqveland, David W Stockton, Eva Trevisson, Nicole J Ullrich, Meena Upadhyaya, Rick van Minkelen, Helene Verhelst, Margaret R Wallace, Yoon-Sim Yap, Elaine Zackai, Jonathan Zonana, Vickie Zurcher, Kathleen Claes, Yolanda Martin, Bruce R Korf, Eric Legius, Ludwine M Messiaen
Neurofibromatosis type 1 (NF1), a common genetic disorder with a birth incidence of 1:2,000-3,000, is characterized by a highly variable clinical presentation. To date, only two clinically relevant intragenic genotype-phenotype correlations have been reported for NF1 missense mutations affecting p.Arg1809 and a single amino acid deletion p.Met922del. Both variants predispose to a distinct mild NF1 phenotype with neither externally visible cutaneous/plexiform neurofibromas nor other tumors. Here, we report 162 individuals (129 unrelated probands and 33 affected relatives) heterozygous for a constitutional missense mutation affecting one of five neighboring NF1 codons-Leu844, Cys845, Ala846, Leu847, and Gly848-located in the cysteine-serine-rich domain (CSRD)...
December 21, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/29290322/-nevus-lipomatosus-cutaneous-superficialis-report-of-four-cases-including-an-unusual-presentation-associated-with-massive-lipomas-and-diffuse-lipomatosis
#13
Mariana Medell-Gago, Tamara Guerra-Guerra, Orlando González-Pérez, Leonardo Concepción-Quiñones
Nevus lipomatosus cutaneus superficialis is a rare, hamartomatous disorder, characterized by the presence of ectopic mature adipose tissue within the superficial dermis. Lesions occur within the first three decades of life. We report four new cases, including a patient with the most extensive affectation reported to date, which was associated with massive lipomas in the subcutaneous cell tissue and diffuse lipomatosis. To our knowledge, it is the first report of this disorder in Cuba.
January 2018: Revista Española de Patología
https://www.readbyqxmd.com/read/29283374/tongue-abnormalities-are-associated-to-a-maternal-folic-acid-deficient-diet-in-mice
#14
Estela Maldonado, Yamila López-Gordillo, Teresa Partearroyo, Gregorio Varela-Moreiras, Concepción Martínez-Álvarez, Juliana Pérez-Miguelsanz
It is widely accepted that maternal folic acid (FA) deficiency during pregnancy is a risk factor for abnormal development. The tongue, with multiple genes working together in a coordinated cascade in time and place, has emerged as a target organ for testing the effect of FA during development. A FA-deficient (FAD) diet was administered to eight-week-old C57/BL/6J mouse females for 2-16 weeks. Pregnant dams were sacrificed at gestational day 17 (E17). The tongues and heads of 15 control and 210 experimental fetuses were studied...
December 28, 2017: Nutrients
https://www.readbyqxmd.com/read/29278847/analysis-of-the-wuschel-related-homeobox-gene-family-in-pinus-pinaster-new-insights-into-the-gene-family-evolution
#15
José M Alvarez, Natalia Bueno, Rafael A Cañas, Concepción Avila, Francisco M Cánovas, Ricardo J Ordás
WUSCHEL-RELATED HOMEOBOX (WOX) genes are key players controlling stem cells in plants and can be divided into three clades according to the time of their appearance during plant evolution. Our knowledge of stem cell function in vascular plants other than angiosperms is limited, they separated from gymnosperms ca 300 million years ago and their patterning during embryogenesis differs significantly. For this reason, we have used the model gymnosperm Pinus pinaster to identify WOX genes and perform a thorough analysis of their gene expression patterns...
December 21, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29276837/effects-of-behavioral-activation-on-the-quality-of-life-and-emotional-state-of-lung-cancer-and-breast-cancer-patients-during-chemotherapy-treatment
#16
Concepción Fernández-Rodríguez, Erica Villoria-Fernández, Paula Fernández-García, Sonia González-Fernández, Marino Pérez-Álvarez
Research suggests that the progressive abandonment of activities in cancer patients are related to depression and worse quality of life. Behavioral activation (BA) encourages subjects to activate their sources of reinforcement and modify the avoidance responses. This study assesses the effectiveness of BA in improving quality of life and preventing emotional disorders during chemotherapy treatment. One sample of lung cancer patients and another of breast cancer patients were randomized into a BA experimental group (E...
December 1, 2017: Behavior Modification
https://www.readbyqxmd.com/read/29274802/susceptibility-testing-and-detection-of-%C3%AE-lactam-resistance-mechanisms-in-enterobacteriaceae-a-multicentre-national-proficiency-study
#17
María Díez-Aguilar, María-Carmen Conejo, María-Isabel Morosini, Núria Tormo Palop, Concepción Gimeno, Rafael Cantón, Álvaro Pascual
A nationwide study was developed to evaluate the ability of 60 Spanish clinical microbiology laboratories to predict the underlying β-lactam resistance mechanisms of 12 Enterobacteriaceae strains (CCS01-CCS12). Results obtained by two reference laboratories were compared with those reported by the participants that used their own routine susceptibility testing methodology. CLSI interpretive criteria were used in 53.3% of the centres, while 46.7% used EUCAST. The overall categorical agreement (CA) was 85.5%...
December 21, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29258569/leishmania-braziliensis-scd6-and-rbp42-proteins-two-factors-with-rna-binding-capacity
#18
Paola A Nocua, Cesar A Ramirez, José M Requena, Concepción J Puerta
BACKGROUND: The study of RNA binding proteins (RBPs) is of great relevance for understanding processes like post-transcriptional control of gene expression. The post-transcriptional mechanisms are particularly important in Leishmania parasites and related trypanosomatids since transcriptional regulation is almost absent in them. Thus, RBPs should be essential during the development of these parasites and for survival strategies against the adverse conditions that they face during their life-cycle...
December 19, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29243155/trends-in-plant-research-using-molecular-markers
#19
REVIEW
Jose Antonio Garrido-Cardenas, Concepción Mesa-Valle, Francisco Manzano-Agugliaro
A deep bibliometric analysis has been carried out, obtaining valuable parameters that facilitate the understanding around the research in plant using molecular markers. The evolution of the improvement in the field of agronomy is fundamental for its adaptation to the new exigencies that the current world context raises. In addition, within these improvements, this article focuses on those related to the biotechnology sector. More specifically, the use of DNA markers that allow the researcher to know the set of genes associated with a particular quantitative trait or QTL...
December 14, 2017: Planta
https://www.readbyqxmd.com/read/29242209/circulating-hypergranular-neoplastic-cells-not-always-leukemic-promyelocytes
#20
Concepción Prats-Martín, Rosario M Morales-Camacho
No abstract text is available yet for this article.
December 14, 2017: Blood
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