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Visceral obesity cardiovascular risk factor

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https://www.readbyqxmd.com/read/28428538/hyperuricemia-is-associated-with-cardiovascular-diseases-clustering-among-very-elderly-women-a-community-based-study-in-chengdu-china
#1
Gang Huang, Jun-Bo Xu, Ting-Jie Zhang, Xiao-Li Nie, Qiu Li, Ya Liu, Yan Lv, Rui-Lian Wen, Lei Yang, Bao-Yu Zhao
Cardiovascular epidemiological features among very elderly Chinese are still uncertain. This study aimed to describe the distribution of cardiovascular diseases and sex difference, and investigate potential risk factors for diseases clustering among very elderly Chinese. From May 2013 to May 2015, a total of 1056 very elderly were sampled in this cross-sectional study. Demographic characteristics collection, physical examination and biochemical analysis were performed. Totally, 1038 participants (men: 49.8%) with a median age of 83...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28376896/regulation-of-visceral-and-epicardial-adipose-tissue-for-preventing-cardiovascular-injuries-associated-to-obesity-and-diabetes
#2
REVIEW
N González, Z Moreno-Villegas, A González-Bris, J Egido, Ó Lorenzo
Nowadays, obesity is seriously increasing in most of the populations all over the world, and is associated with the development and progression of high-mortality diseases such as type-2 diabetes mellitus (T2DM) and its subsequent cardiovascular pathologies. Recent data suggest that both body fat distribution and adipocyte phenotype, can be more determinant for fatal outcomes in obese patients than increased general adiposity. In particular, visceral adiposity is significantly linked to long term alterations on different cardiac structures, and in developed forms of myocardial diseases such as hypertensive and ischaemic heart diseases, and diabetic cardiomyopathy...
April 4, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28363402/effect-of-roux-en-y-gastric-bypass-on-carotid-intima-media-thickness-in-chinese-obese-patients-with-type-2-diabetes
#3
Jie Chen, Haoyong Yu, Li Chen, Lei Wu, Bing Hu, Yuqian Bao, Lixin Jiang
BACKGROUND: The effect of Roux-en-Y gastric bypass (RYGB) on carotid intima-media thickness (C-IMT) in obese patients with type 2 diabetes (T2D) has not been well studied. OBJECTIVE: To investigate the effect of RYGB on C-IMT and the relationship between C-IMT and some cardiovascular risk factors 12 months after surgery on Chinese obese patients with T2D. SETTING: University hospital, China. METHODS: Thirty-three consecutive obese patients with T2D and 18 healthy volunteers matched in age and sex were enrolled in this retrospective study...
February 3, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28326296/association-between-sarcopenic-obesity-and-metabolic-syndrome-in-postmenopausal-women-a-cross-sectional-study-based-on-the-korean-national-health-and-nutritional-examination-surveys-from-2008-to-2011
#4
Sun-Young Kang, Gyeong Eun Lim, Yang Keun Kim, Hye Won Kim, Kayoung Lee, Tae-Jin Park, Jinseung Kim
BACKGROUND: Menopause contributes to an increase in visceral fat mass and a decrease in muscle protein synthesis. Therefore, we performed this study to examine their relationship how effect the changes of body composition as obesity and sarcopenia on metabolic syndrome (MS) as a predictor of cardiovascular disease in postmenopausal women. METHODS: Using data from the Korean National Health and Nutrition Examination Survey (KNHANES) from 2008 to 2011, we estimated that 4,183 postmenopausal women underwent dual energy X-ray absorptiometry scans...
February 2017: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/28274579/the-impact-of-fat-distribution-on-subclinical-coronary-atherosclerosis-in-middle-aged-chinese-adults
#5
Lin Ding, Kui Peng, Lin Lin, Mian Li, Tiange Wang, Meng Dai, Zhiyun Zhao, Min Xu, Jieli Lu, Yuhong Chen, Weiqing Wang, Yufang Bi, Yu Xu, Guang Ning
BACKGROUND: The relationship between obesity and cardiovascular disease (CVD) depends not only on the amount of body fat but also on its distribution, which has not been fully investigated in Chinese populations. We aimed to compare measures of fat accumulation in associations with subclinical coronary atherosclerosis in middle-aged Chinese adults. METHODS: A total of 548 participants aged 40-60years without previous history or clinical symptoms of CVD were randomly selected to undergo abdominal computed tomography (CT) scanning and coronary CT angiography for the evaluation of subcutaneous and visceral fat accumulation and coronary atherosclerosis, respectively...
May 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28271466/intestinal-microbiota-in-type-2-diabetes-and-chronic-kidney-disease
#6
REVIEW
Alice Sabatino, Giuseppe Regolisti, Carmela Cosola, Loreto Gesualdo, Enrico Fiaccadori
PURPOSE OF THE REVIEW: Diabetes mellitus is a major cause of kidney disease [chronic kidney disease (CKD) and end-stage renal disease (ESRD)] and are both characterized by an increased risk of cardiovascular events. Diabetes and kidney disease are also commonly associated with a chronic inflammatory state, which is now considered a non-traditional risk factor for atherosclerosis. In the case of type 2 diabetes mellitus (T2DM), inflammation is mainly a consequence of visceral obesity, while in the case of CKD or ESRD patients on dialysis, inflammation is caused by multiple factors, classically grouped as dialysis-related and non-dialysis-related...
March 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28261588/comparison-of-visceral-fat-accumulation-and-metabolome-markers-among-cats-of-varying-bcs-and-novel-classification-of-feline-obesity-and-metabolic-syndrome
#7
Yuki Okada, Motoo Kobayashi, Masaki Sawamura, Toshiro Arai
As in humans, obesity and its associated diseases represent the most significant threat to the health of veterinary populations. Previous human studies have provided insights into the risk factors of obesity, complex pathogenesis of obesity-associated diseases, and their life-threatening consequences. In humans, the "metabolic syndrome" represents a cluster of metabolic risk factors associated with the development of cardiovascular disease. Risk factors for metabolic syndrome, such as diabetes, obesity, high blood pressure, and its complications increase health-care utilization and medical expenses...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28254124/left-ventricular-function-across-the-spectrum-of-body-mass-index-in-african%C3%A2-americans-the-jackson-heart-study
#8
Vivek G Patel, Deepak K Gupta, James G Terry, Edmond K Kabagambe, Thomas J Wang, Aldolfo Correa, Michael Griswold, Herman Taylor, John Jeffrey Carr
OBJECTIVES: This study sought to assess whether body mass index (BMI) was associated with subclinical left ventricular (LV) systolic dysfunction in African-American individuals. BACKGROUND: Higher BMI is a risk factor for cardiovascular disease, including heart failure. Obesity disproportionately affects African Americans; however, the association between higher BMI and LV function in African Americans is not well understood. METHODS: Peak systolic circumferential strain (ECC) was measured by tagged cardiac magnetic resonance in 1,652 adult African-American participants of the Jackson Heart Study between 2008 and 2012...
March 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28095471/prevalence-and-risk-factors-of-prehypertension-and-hypertension-in-southern-china
#9
Lihua Hu, Xiao Huang, Chunjiao You, Juxiang Li, Kui Hong, Ping Li, Yanqing Wu, Qinhua Wu, Huihui Bao, Xiaoshu Cheng
BACKGROUND: This study aimed to describe the prevalence and risk factors of prehypertension and hypertension in Jiangxi Province, China. Individuals with prehypertension frequently progress into hypertension and are at high risk of developing cardiovascular disease and stroke. METHODS: A cross-sectional survey of 15,296 participants (15 years or older) was conducted in Jiangxi Province, China, in 2013, using questionnaire forms and physical measurements. RESULTS: The prevalence of prehypertension and hypertension was 32...
2017: PloS One
https://www.readbyqxmd.com/read/28029015/association-between-blood-mercury-level-and-visceral-adiposity-in-adults
#10
Jong Suk Park, Kyoung Hwa Ha, Ka He, Dae Jung Kim
BACKGROUND: Few studies have examined the association between mercury exposure and obesity. The aim of this study is to investigate the association between blood mercury concentrations and indices of obesity in adults. METHODS: A total of 200 healthy subjects, aged 30 to 64 years, who had no history of cardiovascular or malignant disease, were examined. Anthropometric and various biochemical profiles were measured. Visceral adipose tissue (VAT) was measured using dual-energy X-ray absorptiometry (DXA)...
December 21, 2016: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28027796/associations-of-serum-fibroblast-growth-factor-23-levels-with-obesity-and-visceral-fat-accumulation
#11
Xiang Hu, Xiaojing Ma, Yuqi Luo, Yiting Xu, Qin Xiong, Xiaoping Pan, Yunfeng Xiao, Yuqian Bao, Weiping Jia
BACKGROUND & AIMS: Recent findings raise the possibility that fibroblast growth factor (FGF) 23 may be related with fat contents and distribution. The present study aimed to elucidate the associations of serum FGF23 levels with the fat contents and distribution. METHODS: A total of 1599 normoglycemic individuals with preserved kidney function were enrolled. Serum levels of intact FGF23 were detected using a sandwich enzyme-linked immunosorbent assay. Overweight/obesity was defined by a body mass index of ≥25...
December 18, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28026829/retinol-binding-protein-4-rbp4-as-the-causative-factor-and-marker-of-vascular-injury-related-to-insulin-resistance
#12
Marcin Majerczyk, Magdalena Olszanecka-Glinianowicz, Monika Puzianowska-Kuźnicka, Jerzy Chudek
One of adipokines involved in the development of insulin resistance is retinol-binding protein 4(RBP4). The physiological role of RBP4 is transport of retinol from the liver to peripheral tissues. One of the first events related to the excessive visceral fat accumulation is the development of inflammation followed by hormonal adipose tissue dysfunction, including excessive RBP4 production. Reduced density of the membrane-type glucose transporter 4 (GLUT4) is considered as a direct cause for the stimulation of RBP4 release to the circulation by adipocytes...
December 21, 2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28012616/-sensitivity-and-specificity-of-abdominal-adiposity-with-metabolic-syndrome-in-the-elderly
#13
José Ramón Alvero-Cruz, Rosalía Fernández Vázquez, María Del Mar García Vega, Juan Antonio García Lavigne, María Victoria Rodríguez Linares, Javier Martínez Blanco
OBJECTIVES: It is recognised that abdominal adiposity is associated with cardiovascular risk factors, such as intolerance to glucose, hypertension and dyslipidaemia. The objective of the present study was to assess the relationship of trunk fat and visceral fat index, obtained by anthropometric and bioelectrical impedance, with metabolic syndrome (SM) in an elderly population. METHODS: The study included 208 subjects (78 men and 130 women) with a mean age of 82...
December 21, 2016: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/27981440/visceral-fat-is-associated-with-brain-structure-independent-of-human-immunodeficiency-virus-infection-status
#14
Jordan E Lake, Mikhail Popov, Wendy S Post, Frank J Palella, Ned Sacktor, Eric N Miller, Todd T Brown, James T Becker
The combined effects of human immunodeficiency virus (HIV), obesity, and elevated visceral adipose tissue (VAT) on brain structure are unknown. In a cross-sectional analysis of Multicenter AIDS Cohort Study (MACS) participants, we determined associations between HIV serostatus, adiposity, and brain structure. Men (133 HIV+, 84 HIV-) in the MACS Cardiovascular 2 and magnetic resonance imaging (MRI) sub-studies with CT-quantified VAT and whole brain MRI measured within 1 year were assessed. Voxel-based morphometry analyzed brain volumes...
December 15, 2016: Journal of Neurovirology
https://www.readbyqxmd.com/read/27958252/comparison-of-the-body-compositions-in-obese-and-nonobese-individuals-can-learning-body-compositions-motivate-losing-weight
#15
R Kutlu, F G Cihan
BACKGROUND: Obesity is one of the leading preventable causes of death worldwide. OBJECTIVE: To compare body compositions in obese and nonobese individuals. METHODS: This cross-sectional study constituted of 428 individuals. Body compositions were determined using the Tanita. RESULTS: Of all the participants, 300 (70.1%) were female. The prevalence of overweight and obesity was 30.8% and 47.7%, respectively. Having low educational level, female gender, not working, being married, and nonsmoker significantly increased more in obese than nonobese (P < 0...
January 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/27933093/long-term-consumption-of-an-obesogenic-high-fat-diet-prior-to-ischemia-reperfusion-mediates-cardioprotection-via-epac1-dependent-signaling
#16
F Edland, A Wergeland, R Kopperud, K S Åsrud, E A Hoivik, S L Witsø, R Æsøy, L Madsen, K Kristiansen, M Bakke, S O Døskeland, A K Jonassen
BACKGROUND: Obesity is still considered a risk factor for cardiovascular disease, although more recent knowledge also suggests obesity to be associated with reduced morbidity and mortality - the "obesity paradox". This study explores if long-term feeding of an obesogenic high fat diet renders the myocardium less susceptible to ischemic-reperfusion induced injury via Epac-dependent signaling. METHODS: Wild type (wt), Epac1 (Epac1(-/-)) and Epac2 (Epac2(-/-)) deficient mice were fed a high fat (HFD) or normal chow diet (ND) for 33 ± 1 weeks...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27921043/metabolic-vascular-syndrome-new-insights-into-a-multidimensional-network-of-risk-factors-and-diseases
#17
REVIEW
Gerhard H Scholz, Markolf Hanefeld
BACKGROUND: Since 1981, we have used the term metabolic syndrome to describe an association of a dysregulation in lipid metabolism (high triglycerides, low high-density lipoprotein cholesterol, disturbed glucose homeostasis (enhanced fasting and/or prandial glucose), gout, and hypertension), with android obesity being based on a common soil (overnutrition, reduced physical activity, sociocultural factors, and genetic predisposition). We hypothesized that main traits of the syndrome occur early and are tightly connected with hyperinsulinemia/insulin resistance, procoagulation, and cardiovascular diseases...
October 2016: Visceral Medicine
https://www.readbyqxmd.com/read/27865196/-browning-the-cardiac-and-peri-vascular-adipose-tissues-to-modulate-cardiovascular-risk
#18
REVIEW
Peter Aldiss, Graeme Davies, Rachel Woods, Helen Budge, Harold S Sacks, Michael E Symonds
Excess visceral adiposity, in particular that located adjacent to the heart and coronary arteries is associated with increased cardiovascular risk. In the pathophysiological state, dysfunctional adipose tissue secretes an array of factors modulating vascular function and driving atherogenesis. Conversely, brown and beige adipose tissues utilise glucose and lipids to generate heat and are associated with improved cardiometabolic health. The cardiac and thoracic perivascular adipose tissues are now understood to be composed of brown adipose tissue in the healthy state and undergo a brown-to-white transition i...
February 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27796618/distinct-secretory-activity-and-clinical-impact-of-subcutaneous-abdominal-adipose-tissue-in-women-with-rheumatoid-arthritis-and-osteoarthritis
#19
Ewa Kontny, Agnieszka Zielińska, Urszula Skalska, Krystyna Księżopolska-Orłowska, Piotr Głuszko, Włodzimierz Maśliński
In the general population, low-grade inflammation of adipose tissue accompanies obesity and contributes to cardiovascular disease (CVD) development, but the implication of this tissue in rheumatic disease pathology is unclear. Therefore, we characterized the secretory activity of subcutaneous abdominal adipose tissue (SAAT) of females with rheumatoid arthritis (RA) and osteoarthritis (OA) and searched for its relationship with intensity of systemic inflammation, body composition and comorbidity. The secretion of classical adipokines (leptin, adiponectin), pro- and anti-inflammatory factors, i...
October 28, 2016: Inflammation
https://www.readbyqxmd.com/read/27765543/the-ratio-between-visceral-and-subcutaneous-abdominal-fat-assessed-by-computed-tomography-is-an-independent-predictor-of-mortality-and-cardiac-events
#20
Ricardo Ladeiras-Lopes, Francisco Sampaio, Nuno Bettencourt, Ricardo Fontes-Carvalho, Nuno Ferreira, Adelino Leite-Moreira, Vasco Gama
INTRODUCTION AND OBJECTIVES: Obesity is an important cardiovascular risk factor and the location of fat deposits seems to be an important determinant of its metabolic impact. Visceral adipose tissue (VAT) exerts a harmful effect on metabolic homeostasis, but few longitudinal studies have evaluated the prognostic impact of the ratio of VAT to subcutaneous adipose tissue (SAT). This study aimed to evaluate whether the VAT/SAT ratio was associated with all-cause mortality and cardiac events...
October 17, 2016: Revista Española de Cardiología
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