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https://www.readbyqxmd.com/read/28421990/elevated-levels-of-soluble-cd40-ligand-are-associated-with-antiphospholipid-antibodies-in-patients-with-systemic-lupus-erythematosus
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Ki-Jo Kim, In-Woon Baek, Chong-Hyeon Yoon, Wan-Uk Kim, Chul-Soo Cho
OBJECTIVES: The CD40L/CD40 pathway is involved in the pathophysiology of atherothrombotic disease, and elevated levels of soluble CD40L (sCD40L) were reported in SLE patients. However, the clinical implication of sCD40L in SLE remains elusive. METHODS: We measured levels of plasma sCD40L in 241 SLE patients and 37 healthy controls and investigated its association with clinical manifestation and laboratory parameters. RESULTS: Levels of plasma sCD40L in SLE patients were significantly elevated compared with healthy controls (p=0...
April 18, 2017: Clinical and Experimental Rheumatology
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