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https://www.readbyqxmd.com/read/29166245/evidence-supporting-li-rads-major-features-for-ct-and-mr-imaging-based-diagnosis-of-hepatocellular-carcinoma-a-systematic-review
#1
An Tang, Mustafa R Bashir, Michael T Corwin, Irene Cruite, Christoph F Dietrich, Richard K G Do, Eric C Ehman, Kathryn J Fowler, Hero K Hussain, Reena C Jha, Adib R Karam, Adrija Mamidipalli, Robert M Marks, Donald G Mitchell, Tara A Morgan, Michael A Ohliger, Amol Shah, Kim-Nhien Vu, Claude B Sirlin
The Liver Imaging Reporting and Data System (LI-RADS) standardizes the interpretation, reporting, and data collection for imaging examinations in patients at risk for hepatocellular carcinoma (HCC). It assigns category codes reflecting relative probability of HCC to imaging-detected liver observations based on major and ancillary imaging features. LI-RADS also includes imaging features suggesting malignancy other than HCC. Supported and endorsed by the American College of Radiology (ACR), the system has been developed by a committee of radiologists, hepatologists, pathologists, surgeons, lexicon experts, and ACR staff, with input from the American Association for the Study of Liver Diseases and the Organ Procurement Transplantation Network/United Network for Organ Sharing...
November 21, 2017: Radiology
https://www.readbyqxmd.com/read/29165941/-allocation-of-time-in-internal-medicine
#2
Nathalie Wenger, Pedro Marques-Vidal
The hospital internal medicine practice is changing : increasing complexity of patients; implementation of the Electronic Medical Record (EMR); growing volume of medical data and administrative tasks, and limitation of working hours. We quantified the daily tasks of our internal medicine residents. They didn't manage to fulfill their duties in the scheduled time and had to stay after hours ; further, activities indirectly related to patients predominated. Residents spent a daily average of 1.7 hours with patients, 5...
November 22, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29164950/the-institutional-foundations-of-medicalization-a-cross-national-analysis-of-mental-health-and-unemployment
#3
Veerle Buffel, Jason Beckfield, Piet Bracke
In this study, we question (1) whether the relationship between unemployment and mental healthcare use, controlling for mental health status, varies across European countries and (2) whether these differences are patterned by a combination of unemployment and healthcare generosity. We hypothesize that medicalization of unemployment is stronger in countries where a low level of unemployment generosity is combined with a high level of healthcare generosity. A subsample of 36,306 working-age respondents from rounds 64...
September 2017: Journal of Health and Social Behavior
https://www.readbyqxmd.com/read/29162113/determination-of-the-residual-efficacy-of-carbamate-and-organophosphate-insecticides-used-for-indoor-residual-spraying-for-malaria-control-in-ethiopia
#4
Delenasaw Yewhalaw, Meshesha Balkew, Josephat Shililu, Sultan Suleman, Alemayehu Getachew, Gedeon Ashenbo, Sheleme Chibsa, Gunawardena Dissanayake, Kristen George, Dereje Dengela, Yemane Ye-Ebiyo, Seth R Irish
BACKGROUND: Indoor residual spraying is one of the key vector control interventions for malaria control in Ethiopia. As malaria transmission is seasonal in most parts of Ethiopia, a single round of spraying can usually provide effective protection against malaria, provided the insecticide remains effective over the entire malaria transmission season. This experiment was designed to evaluate the residual efficacy of bendiocarb, pirimiphos-methyl, and two doses of propoxur on four different wall surfaces (rough mud, smooth mud, dung, and paint)...
November 21, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29155826/programmatic-factors-associated-with-the-limited-impact-of-community-directed-treatment-with-ivermectin-to-control-onchocerciasis-in-three-drainage-basins-of-south-west-cameroon
#5
Christian Tetteh Duamor, Fabrice Roberto Datchoua-Poutcheu, Winston Patrick Chounna Ndongmo, Aldof Tah Yoah, Ernest Njukang, Emmanuel Kah, Mary Sheena Maingeh, Jonas Arnaud Kengne-Ouaffo, Dizzle Bita Tayong, Peter A Enyong, Samuel Wanji
INTRODUCTION: The CDTI model is known to have enhanced community participation in planning and resource mobilization toward the control of onchocerciasis. These effects were expected to translate into better individual acceptance of the intervention and hence high Treatment Coverage, leading to a sustainable community-led strategy and reduction in the disease burden. A survey revealed that after 10-12 rounds of treatment, prevalence of onchocerciasis was still high in three drainage basins of South West Cameroon and transmission was going on...
November 20, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29153070/-the-importance-of-the-contribution-of-rapid-test-serological-and-molecular-methods-in-the-diagnosis-of-two-imported-malaria-cases-with-atypical-microscopy
#6
Orçun Zorbozan, Hüsnü Pullukçu, Esra Atalay Şahar, Muhammet Karakavuk, Hüseyin Can, Varol Tunali, Mert Döşkaya, Nevin Turgay, Seray Töz, Ahmet Özbilgin
Malaria is a widespread and life-threatening disease in tropical and subtropical regions. In patients with typical clinical symptoms, malaria is considered as a preliminary diagnosis if there is a travel history to malaria-endemic areas. The basis of the laboratory diagnosis of malaria is the microscopic examination of Giemsa stained smears. On the other hand, the diagnosis and differentiation of Plasmodium species with microscopic examination may have some difficulties. In the first case, adifferent appearance from the classical Plasmodium vivax erythrocytic forms in infected erythrocytes were detected in 1% of all erythrocytes in thin smear blood preparations of a 26-year-old male with complaints of fever and chills and a story of travel to Nigeria...
October 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/29152104/a-developed-model-of-cancer-patients-participation-in-intravenous-chemotherapy-safety
#7
Zeng Na, Yan Qiaoyuan, Wang Binghan, Zhu Qin, Chen Yue, Peng Xin, Tan Cuilian, Yao Cheng
How to reduce intravenous chemotherapy-related adverse reactions of cancer patients is one focus of clinical work. Nowadays, patient for patient safety (PFPS) is an important component of hospital safety management and can contribute to a reduction in the rate of adverse events following intravenous chemotherapy of cancer patients. To guide and evaluate cancer patients participate in intravenous chemotherapy, we explored a scientific and practical model of cancer patients participation in intravenous chemotherapy safety...
October 20, 2017: Oncotarget
https://www.readbyqxmd.com/read/29149505/an-international-continence-society-ics-report-on-the-terminology-for-adult-neurogenic-lower-urinary-tract-dysfunction-anlutd
#8
Jerzy B Gajewski, Brigitte Schurch, Rizwan Hamid, Márcio Averbeck, Ryuji Sakakibara, Enrico F Agrò, Tamara Dickinson, Christopher K Payne, Marcus J Drake, Bernie T Haylen
INTRODUCTION: The terminology for adult neurogenic lower urinary tract dysfunction (ANLUTD) should be defined and organized in a clinically based consensus Report. METHODS: This Report has been created by a Working Group under the auspices and guidelines of the International Continence Society (ICS) Standardization Steering Committee (SSC) assisted at intervals by external referees. All relevant definitions for ANLUTD were updated on the basis of research over the last 14 years...
November 17, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29147790/-etomidate-for-intravenous-induction-of-anaesthesia
#9
C Dumps, D Bolkenius, E Halbeck
The pharmacological and historical knowledge about the currently available intravenous induction hypnotics form the basis for the daily work of anesthetists. Side effects of using hypnotic induction agents must be anticipated and adequately treated. Decades of experience with using intravenous induction hypnotics have led to theoretical requirements for an ideal narcotic agent with a best possible side effect profile. In the absence of this optimal hypnotic induction agent, a careful selection of one or a combination of narcotic drugs is necessary to meet the needs of the respective risk constellation of the patient...
November 16, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/29133329/involvement-of-people-with-dementia-in-making-decisions-about-their-lives-a-qualitative-study-that-appraises-shared-decision-making-concerning-daycare
#10
Leontine Groen-van de Ven, Carolien Smits, Fuusje de Graaff, Marijke Span, Jan Eefsting, Jan Jukema, Myrra Vernooij-Dassen
OBJECTIVE: To explore how people with dementia, their informal caregivers and their professionals participate in decision making about daycare and to develop a typology of participation trajectories. DESIGN: A qualitative study with a prospective, multiperspective design, based on 244 semistructured interviews, conducted during three interview rounds over the course of a year. Analysis was by means of content analysis and typology construction. SETTING: Community settings and nursing homes in the Netherlands...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29131914/pediatric-orbital-primitive-neuroectodermal-tumors
#11
Tayyab Afghani, Hassan Mansoor, Syed Naeem Raza Hamdani
PURPOSE: To present the clinical, radiological, histopathological, immunohistochemical features and the follow-up of orbital primitive neuroectodermal tumors (PNETs) in pediatric patients along with a review of the literature. METHODS: A retrospective analysis of all diagnosed cases of orbital PNET was done. Patients' ophthalmic findings, imaging, immunohistochemistry, metastatic work-up, treatment, globe salvation, and survival were documented and a mini literature review of orbital PNET was performed...
November 11, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29130812/mutual-point-winning-probabilities-mpw-a-new-performance-measure-for-table-tennis
#12
Christophe Ley, Yves Dominicy, Wim Bruneel
We propose a new performance measure for table tennis players: the mutual point-winning probabilities (MPW) as server and receiver. The MPWs quantify a player's chances to win a point against a given opponent, and hence nicely complement the classical match statistics history between two players. These new quantities are based on a Bradley-Terry-type statistical model taking into account the importance of individual points, since a rally at 8-2 in the first set is less crucial than a rally at the score of 9-9 in the final set...
November 13, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29126410/more-than-visual-literacy-art-and-the-enhancement-of-tolerance-for-ambiguity-and-empathy
#13
Miriam Ethel Bentwich, Peter Gilbey
BACKGROUND: Comfort with ambiguity, mostly associated with the acceptance of multiple meanings, is a core characteristic of successful clinicians. Yet past studies indicate that medical students and junior physicians feel uncomfortable with ambiguity. Visual Thinking Strategies (VTS) is a pedagogic approach involving discussions of art works and deciphering the different possible meanings entailed in them. However, the contribution of art to the possible enhancement of the tolerance for ambiguity among medical students has not yet been adequately investigated...
November 10, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/29121350/individualized-fsh-dosing-based-on-ovarian-reserve-testing-in-women-starting-ivf-icsi-a-multicentre-trial-and-cost-effectiveness-analysis
#14
Theodora C van Tilborg, Simone C Oudshoorn, Marinus J C Eijkemans, Monique H Mochtar, Ron J T van Golde, Annemieke Hoek, Walter K H Kuchenbecker, Kathrin Fleischer, Jan Peter de Bruin, Henk Groen, Madelon van Wely, Cornelis B Lambalk, Joop S E Laven, Ben Willem J Mol, Frank J M Broekmans, Helen L Torrance
STUDY QUESTION: Is there a difference in live birth rate and/or cost-effectiveness between antral follicle count (AFC)-based individualized FSH dosing or standard FSH dosing in women starting IVF or ICSI treatment? SUMMARY ANSWER: In women initiating IVF/ICSI, AFC-based individualized FSH dosing does not improve live birth rates or reduce costs as compared to a standard FSH dose. WHAT IS KNOWN ALREADY: In IVF or ICSI, ovarian reserve testing is often used to adjust the FSH dose in order to normalize ovarian response and optimize live birth rates...
November 7, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29119776/between-worst-and-best-developing-criteria-to-identify-promising-practices-in-health-promotion-and-disease-prevention-for-the-canadian-best-practices-portal
#15
Nadia Fazal, Suzanne F Jackson, Katy Wong, Jennifer Yessis, Nina Jetha
INTRODUCTION: In health promotion and chronic disease prevention, both best and promising practices can provide critical insights into what works for enhancing the healthrelated outcomes of individuals and communities, and how/why these practices work in different situations and contexts. METHODS: The promising practices criteria were developed using the Public Health Agency of Canada's (PHAC's) existing best practices criteria as the foundation. They were modified and pilot tested (three rounds) using published interventions...
November 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/29118123/estimating-initial-viral-levels-during-hiv-siv-reactivation-from-latency
#16
Mykola Pinkevych, Christine M Fennessey, Deborah Cromer, Martin Tolstrup, Ole S Søgaard, Thomas A Rasmussen, Brandon F Keele, Miles P Davenport
HIV viremia rebounds rapidly after treatment interruption, and a variety of strategies are being explored to reduce or control viral reactivation post-treatment. This viral rebound arises from reactivation of individual latently infected cells, which spread during ongoing rounds of productive infection. The level of virus produced by the initial individual reactivating cells is not known, although it may have major implications for the ability of different immune interventions to control viral rebound. Here we use data from both HIV and SIV treatment interruption studies to estimate the initial viral load post-interruption and thereby the initial individual reactivation event...
November 8, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29116047/factors-that-have-an-influence-on-bone-conduction-thresholds-changes-after-otosurgery-in-the-patients-operated-on-due-to-the-perforation-of-the-tympanic-membrane-with-the-preserved-ossicular-chain
#17
Maciej Wiatr, Agnieszka Wiatr, Sebastian Kocoń, Jacek Składzień
INTRODUCTION: The aim of the middle ear surgery is to eliminate abnormalities from the mucous, ensure the due airing of the postoperative cavity and reconstruct the sound-conducting system in the middle ear. Numerous reports can be found in literature on the changes to bone conduction as a consequence of middle ear surgery. STUDY OBJECTIVE: The aim of the work is to define the factors that affect bone conduction in the patients operated on due to the perforation of the tympanic membrane with the preserved and normal mobile ossicular chain...
August 31, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29107679/efficacy-and-safety-of-selective-internal-radiotherapy-with-yttrium-90-resin-microspheres-compared-with-sorafenib-in-locally-advanced-and-inoperable-hepatocellular-carcinoma-sarah-an-open-label-randomised-controlled-phase-3-trial
#18
Valérie Vilgrain, Helena Pereira, Eric Assenat, Boris Guiu, Alina Diana Ilonca, Georges-Philippe Pageaux, Annie Sibert, Mohamed Bouattour, Rachida Lebtahi, Wassim Allaham, Hélène Barraud, Valérie Laurent, Elodie Mathias, Jean-Pierre Bronowicki, Jean-Pierre Tasu, Rémy Perdrisot, Christine Silvain, René Gerolami, Olivier Mundler, Jean-Francois Seitz, Vincent Vidal, Christophe Aubé, Frédéric Oberti, Olivier Couturier, Isabelle Brenot-Rossi, Jean-Luc Raoul, Anthony Sarran, Charlotte Costentin, Emmanuel Itti, Alain Luciani, René Adam, Maïté Lewin, Didier Samuel, Maxime Ronot, Aurelia Dinut, Laurent Castera, Gilles Chatellier
BACKGROUND: Sorafenib is the recommended treatment for patients with advanced hepatocellular carcinoma. We aimed to compare the efficacy and safety of sorafenib to that of selective internal radiotherapy (SIRT) with yttrium-90 ((90)Y) resin microspheres in patients with hepatocellular carcinoma. METHODS: SARAH was a multicentre, open-label, randomised, controlled, investigator-initiated, phase 3 trial done at 25 centres specialising in liver diseases in France. Patients were eligible if they were aged at least 18 years with a life expectancy greater than 3 months, had an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1, Child-Pugh liver function class A or B score of 7 or lower, and locally advanced hepatocellular carcinoma (Barcelona Clinic Liver Cancer [BCLC] stage C), or new hepatocellular carcinoma not eligible for surgical resection, liver transplantation, or thermal ablation after a previously cured hepatocellular carcinoma (cured by surgery or thermoablative therapy), or hepatocellular carcinoma with two unsuccessful rounds of transarterial chemoembolisation...
October 26, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/29107549/myosin-2-induced-mitotic-rounding-enables-columnar-epithelial-cells-to-interpret-cortical-spindle-positioning-cues
#19
Soline Chanet, Rishabh Sharan, Zia Khan, Adam C Martin
During epithelial cell proliferation, planar alignment of the mitotic spindle allows the daughter cells to stay within the epithelium. Previous work has identified cortical cues that regulate spindle orientation and the division axis [1, 2]. One such cue is cortical Pins (LGN in vertebrates) [3-6], which recruits the conserved Mud/NuMA protein and the dynein/dynactin complex to the cortex. The dynein/dynactin motor complex pulls astral microtubules to orient the spindle. Cortical Pins can therefore dictate the division axis...
November 6, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29106310/comparison-of-microtomography-and-optical-coherence-tomography-on-apical-endodontic-filling-analysis
#20
Fernanda Clotilde Mariz Suassuna, Ana Marly Araújo Maia, Daniela Pita Melo, Antônio Celso Dantas Antonino, Anderson Stevens Leônidas Gomes, Patrícia Meira Bento
OBJECTIVES: To comparein vitro differences in the apical filling regarding working length (WL) change and presence of voids and to validate optical coherence tomography (OCT) in comparison with computerized microtomography (µCT) for the detection of failures in the apical filling. METHODS: Forty-five uniradicular teeth with round canals, divided into groups (n = 15) following the obturation protocols: LC (lateral condensation), TMC (thermomechanical compaction) and SC (single cone)...
November 16, 2017: Dento Maxillo Facial Radiology
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