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https://www.readbyqxmd.com/read/28649865/dental-stem-cells-recent-progresses-in-tissue-engineering-and-regenerative-medicine
#1
João Botelho, Maria Alzira Cavacas, Vanessa Machado, José João Mendes
Since the disclosure of adult mesenchymal stem cells (MSCs) there have been an intense investigation on the characteristics of these cells and their potentialities. Dental Stem Cells (DSCs) are MSC-like populations with self-renewal capacity and multidifferentiation potential. Currently, there are five main DSCs, dental pulp stem cells (DPSCs), stem cells from exfoliated deciduous teeth (SHED), stem cells from apical papilla (SCAP), periodontal ligament stem cells (PDLSCs), and Dental Follicle Precursor Cells (DFPCs)...
June 24, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/28646406/podocytes-and-the-quest-for-precision-medicines-for-kidney-diseases
#2
REVIEW
Peter Mundel
In this review, I describe a 30-year journey in the quest for precision medicines for patients with kidney diseases. In 1987, when I started my reseach career, most scientists studying glomerular disease biology were focused on mesangial cells. The crucial role of the podocyte in many kidney diseases characterized by proteinuria, including focal segmental glomerulosclerosis (FSGS) and diabetic nephropathy, had not yet been recognized. We were not aware of genetic causes or drivers of kidney diseases nor of molecular markers and cell culture systems for mechanistic studies of podocyte biology...
June 23, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/28631659/subcutaneous-cysticercosis-presenting-as-cervical-swelling-amazing-and-unexpected-cytological-findings
#3
Punam Prasad Bhadani, Iffat Jamal, Shashikant Kumar, Shuchi Smita
No abstract text is available yet for this article.
April 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28610313/a-case-of-appalachian-endemism-revision-of-the-cambarus-robustus-complex-decapoda-cambaridae-in-the-kentucky-and-licking-river-basins-of-kentucky-usa-with-the-description-of-three-new-species
#4
Zachary J Loughman, Sujan M Henkanaththegedara, James W Fetzner, Roger F Thoma
The amazing levels of freshwater biodiversity found in the Appalachian Mountains of the eastern United States are among the highest recorded globally. Localized endemics make up much of this diversity, with numerous fish, freshwater mussels, salamanders and crayfish often being restricted to a single watershed, and in some instances, subwatersheds. Much of this diversity is the product of the processes of vicariance and historical stream drainage patterns. Herein, we describe three new crayfish species, all previously members of the Cambarus robustus complex, which occur in the Appalachian portion of the Kentucky and Licking river basins in Kentucky, USA...
May 24, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610161/the-amazing-diversity-of-the-genus-i-monospilus-i-sars-1862-crustacea-branchiopoda-aloninae-in-south-america
#5
Francisco Diogo R Sousa, Lourdes M A Elmoor-Loureiro, Eliana A Panarelli
The main goal of this paper is to describe three new species of the genus Monospilus Sars, 1862 (Crustacea: Cladocera). Monospilus macroerosus sp. nov. differs from other species of the genus in several peculiar morphological traits, the most striking being the presence of a saw-shaped pecten of teeth on the postabdominal claw. This species inhabits semiterrestrial habitats (wet leaf litter on hydromorphic soil from gallery forest), exhibiting adaptations related to movement and food handling in this type of habitat...
March 13, 2017: Zootaxa
https://www.readbyqxmd.com/read/28605672/intercellular-transfer-of-organelles-during-body-pigmentation
#6
REVIEW
Ryosuke Tadokoro, Yoshiko Takahashi
The intercellular transfer of the melanin-producing organelle, called melanosome, from melanocytes to adjacent keratinocytes, is largely responsible for the coat colors and skin pigmentation of amniotes (birds, reptiles, and mammals). Although several hypotheses of melanin-transfer were proposed mainly by in vitro studies and electron microscopies, how the melanosome transfer takes place in the actual skin remained unclear. With advances in technologies of gene manipulations and high-resolution microscopy that allow direct visualization of plasma membrane, we are beginning to understand the amazing behaviors and dynamics of melanocytes...
June 9, 2017: Current Opinion in Genetics & Development
https://www.readbyqxmd.com/read/28605195/flexible-and-lightweight-fuel-cell-with-high-specific-power-density
#7
Fandi Ning, Xudong He, Yangbin Shen, Hehua Jin, Qingwen Li, Da Li, Shuping Li, Yulu Zhan, Ying Du, Jingjing Jiang, Hui Yang, Xiaochun Zhou
Flexible devices have been attracting great attention recently due to their numerous advantages. But the energy densities of current energy sources are still not high enough to support flexible devices for a satisfactory length of time. Although proton exchange membrane fuel cells (PEMFCs) do have a high-energy density, traditional PEMFCs are usually too heavy, rigid, and bulky to be used in flexible devices. In this research, we successfully invented a light and flexible air-breathing PEMFC by using a new design of PEMFC and a flexible composite electrode...
June 12, 2017: ACS Nano
https://www.readbyqxmd.com/read/28571638/congenital-heart-defects-amazing-advances-and-ongoing-challenges
#8
EDITORIAL
Kathy J Jenkins
No abstract text is available yet for this article.
June 6, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28554296/-an-amazing-feat-of-leadership-meet-the-award-winning-nursing-pioneers
#9
Elaine Cole
A school-age immunisation programme set up from scratch and launched within six months is delivering impressive take-up results thanks to the leadership and commitment of the two nurses who run it.
May 30, 2017: Nursing Management (Harrow)
https://www.readbyqxmd.com/read/28537176/-small-changes-have-a-huge-impact
#10
Elaine Cole
'In the past when my dad was in hospital, I had been made to feel like an intruder without a valid opinion,' says Geraldine Strohm. 'I was amazed to hear that I could get help with the extortionate parking costs. That small gesture meant so much to me, as all thoughts of personal care went out of the window while I was trying to help keep dad alive.'
May 24, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28536368/implications-of-a-multi-step-trigger-of-retinal-regeneration-in-the-adult-newt
#11
Hirofumi Yasumuro, Keisuke Sakurai, Fubito Toyama, Fumiaki Maruo, Chikafumi Chiba
The newt is an amazing four-limbed vertebrate that can regenerate various body parts including the retina. In this animal, when the neural retina (NR) is removed from the eye by surgery (retinectomy), both the NR and the retinal pigment epithelium (RPE) eventually regenerate through the process of reprogramming and proliferation of RPE cells. Thus far, we have pursued the onset mechanism of adult newt retinal regeneration. In this study, using an in vitro system, we found that both mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK and β-catenin were involved in cell cycle re-entry of RPE cells...
May 20, 2017: Biomedicines
https://www.readbyqxmd.com/read/28535854/influenza-a-world-of-discoveries-outbreaks-and-controversy
#12
Wendy S Barclay
Working in an area such as influenza is a free ticket into science communication, a pathway aided amply by the amazing evolutionary powers of the virus; regular outbreaks keep the media engaged and the audience keen. Everyone has heard of flu, and they probably already have an opinion: 'I don't take the vaccine, it gives me the flu anyway.' 'Didn't the government waste loads of money on that Tamiflu drug that doesn't work?' 'I've never had flu because I eat a banana every day and sleep with a boiled onion when I've sat next to someone on the train who was coughing...
May 23, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28532633/amazing-and-fantastic-infection-control-the-case-of-dialyzer%C3%A2-reuse
#13
EDITORIAL
Ezra Gabbay, Klemens B Meyer
No abstract text is available yet for this article.
June 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28528032/a-surprising-alliance-two-giants-of-the-20th-century
#14
Robert M Sade
Alexis Carrel and Charles Lindbergh were among the most famous international figures in the 20th century: Carrel, the surgeon-scientist who won a Nobel prize as a young surgeon, and Lindbergh, the aviator-engineer who pioneered aviation and promoted commercial flight throughout his life. Surprisingly, these two amazing individuals came together to collaborate on the early development of extracorporeal circulation. Their work was interrupted by the onset of World War II, which destroyed one of them and nearly destroyed the other...
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28524647/mutable-properties-of-nonheme-iron-iii-iodosylarene-complexes-result-in-the-elusive-multiple-oxidant-mechanism
#15
Yiran Kang, Xiao-Xi Li, Kyung-Bin Cho, Wei Sun, Chungu Xia, Wonwoo Nam, Yong Wang
Although nonheme iron(III)-iodosylarene complexes present amazing oxidative efficiency and selectivity, the nature of such complexes and related oxidation mechanism are still unsolved after decades of experimental efforts. Density functional calculations were employed to explore the structure-reactivity relationship of the iron(III)-iodosylbenzene complex, [Fe(III)(tpena(-)) (PhIO)](2+) (1), in thioanisole sulfoxidation. Our theoretical work revealed that complex 1 can evolve into two resonance valence-bond electronic structures (a high-valent iron-oxo species and a monomeric PhIO species) in thioanisole sulfoxidation to present different reaction mechanisms (the novel bond-cleavage coupled electron transfer mechanism or the direct oxygen-atom transfer mechanism) as a response to different substrate attack orientations...
June 7, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28522235/a-review-of-terrestrial-aerial-and-aquatic-keratins-the-structure-and-mechanical-properties-of-pangolin-scales-feather-shafts-and-baleen-plates
#16
Bin Wang, Tarah N Sullivan
Keratinous materials, omnipresent as the hard and durable epidermal appendages of animals, are one of the toughest biological materials. They exhibit diverse morphologies and structures that serve a variety of amazing and inspiring mechanical functions. In this work, we provide a review of representative terrestrial, aerial and aquatic keratinous materials, pangolin scales, feather shafts and baleen plates, and correlate their hierarchical structures to respective functions of dermal armor, flight material and undersea filter...
May 8, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28507737/mark-e-josephson-characteristics-of-leadership
#17
EDITORIAL
David J Callans
Mark Josephson is without a doubt the most fascinating person I have ever met. I am proud to have had a close friendship with him and I miss him immensely. I have written in the past about his amazing academic contributions, but in a way I am relieved that this is not my topic today. I will instead talk about the unique aspects of his personality that allowed him to be a great leader in the field of electrophysiology and a powerful influence on the personal development of those of us who had the great good fortune of interacting with him closely...
April 2017: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/28497780/giant-five-photon-absorption-from-multidimensional-core-shell-halide-perovskite-colloidal-nanocrystals
#18
Weiqiang Chen, Saikat Bhaumik, Sjoerd A Veldhuis, Guichuan Xing, Qiang Xu, Michael Grätzel, Subodh Mhaisalkar, Nripan Mathews, Tze Chien Sum
Multiphoton absorption processes enable many technologically important applications, such as in vivo imaging, photodynamic therapy and optical limiting, and so on. Specifically, higher-order nonlinear absorption such as five-photon absorption offers significant advantages of greater spatial confinement, increased penetration depth, reduced autofluorescence, enhanced sensitivity and improved resolution over lower orders in bioimaging. Organic chromophores and conventional semiconductor nanocrystals are leaders in two-/three-photon absorption applications, but face considerable challenges from their small five-photon action cross-sections...
May 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/28495344/does-adoption-of-electronic-health-records-improve-the-quality-of-care-management-in-france-results-from-the-french-e-si-preps-sips-study
#19
Morgane Plantier, Nathalie Havet, Thierry Durand, Nicolas Caquot, Camille Amaz, Pierre Biron, Irène Philip, Lionel Perrier
BACKGROUND: Electronic health records (EHR) are increasingly being adopted by healthcare systems worldwide. In France, the "Hôpital numérique 2012-2017" program was implemented as part of a strategic plan to modernize health information technology (HIT), including the promotion of widespread EHR use. With significant upfront investment costs as well as ongoing operational expenses, it is important to assess this system in terms of its ability to result in improvements in hospital performances...
June 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28485939/creating-quasi-two-dimensional-cluster-assembled-materials-through-self-assembly-of-a-janus-polyoxometalate-silsesquioxane-co-cluster
#20
Han Wu, Yu-Qi Zhang, Min-Biao Hu, Li-Jun Ren, Yue Lin, Wei Wang
Clusters are an important class of nanoscale molecules or superatoms that exhibit an amazing diversity in structure, chemical composition, shape, and functionality. Assembling two types of clusters is creating emerging cluster-assembled materials (CAMs). In this paper, we report an effective approach to produce quasi two-dimensional (2D) CAMs of two types of spherelike clusters, polyhedral oligomeric silsesquioxanes (POSS), and polyoxometalates (POM). To avoid macrophase separation between the two clusters, they are covalently linked to form a POM-POSS cocluster with Janus characteristics and a dumbbell shape...
May 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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