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Eric J Warrant
For over half a century, the multitudinous mirror eyes of the lowly scallop have continuously amazed us with their visual eccentricities. The latest surprise is the mirror itself, which turns out to be an extraordinary optical wonder.
March 19, 2018: Current Biology: CB
Jie Dong, Zhi-Jiang Yao, Lin Zhang, Feijun Luo, Qinlu Lin, Ai-Ping Lu, Alex F Chen, Dong-Sheng Cao
BACKGROUND: With the increasing development of biotechnology and informatics technology, publicly available data in chemistry and biology are undergoing explosive growth. Such wealthy information in these data needs to be extracted and transformed to useful knowledge by various data mining methods. Considering the amazing rate at which data are accumulated in chemistry and biology fields, new tools that process and interpret large and complex interaction data are increasingly important...
March 20, 2018: Journal of Cheminformatics
Colin A Chapman
China is one of the most dynamic countries of the world and it shelters some amazing levels of biodiversity, including some very special primate species. However, primarily as a result of forest loss, most of which occurred in historical times, approximately 70% of China's primate species have less than 3 000 individuals. Here I evaluate one road for future conservation/development that could produce very positive gains for China's primates; namely forest restoration. I argue that for a large scale restoration project to be possible two conditions must be met; the right societal conditions must exist and the right knowledge must be in hand...
March 9, 2018: Zoological Research
Penglun Zheng, Yu Zhang, Zhengfei Dai, Yun Zheng, Khang Ngoc Dinh, Jun Yang, Raksha Dangol, Xiaobo Liu, Qingyu Yan
Heterostructures have attracted increasing attention due to their amazing synergetic effects, which may improve the electrochemical properties, such as good electrical/ionic conductivity, electrochemical activity, and mechanical stability. Herein, novel hierarchical Fe2 O3 @Ni3 Se4 nanotubes are successfully fabricated by a multistep strategy. The nanotubes show length sizes of ≈250-500 nm, diameter sizes of ≈100-150 nm, and wall thicknesses of ≈10 nm. The as-prepared Fe2 O3 @Ni3 Se4 nanotubes with INi:Fe = 1:10 show excellent Li storage properties (897 mAh g-1 high reversible charge capacity at 0...
March 12, 2018: Small
Wei Xuan, Davy Opdenacker, Steffen Vanneste, Tom Beeckman
Plants have an amazing capacity to adjust their growth to environmental limitations. This is particularly relevant for the root system that tunes its developmental pattern to mine the soil for water and nutrients while avoiding patches of soil that contain biotic and abiotic stress agents. Because most developmental processes are taking place gradually while roots are growing, it is often difficult to correlate gene expression events with specific developmental processes that are not necessarily coinciding in time and space...
2018: Methods in Molecular Biology
Gunnar von Heijne
My scientific career has taken me from chemistry, via theoretical physics and bioinformatics, to molecular biology and even structural biology. Along the way, serendipity led me to work on problems such as the identification of signal peptides that direct protein trafficking, membrane protein biogenesis, and cotranslational protein folding. I've had some great collaborations that came about because of a stray conversation or from following up on an interesting paper. And I've had the good fortune to be asked to sit on the Nobel Committee for Chemistry, where I am constantly reminded of the amazing pace and often intricate history of scientific discovery...
March 9, 2018: Journal of Biological Chemistry
Yuya Nishimura, Terumi Matsui, Jun Ishii, Akihiko Kondo
BACKGROUND: To produce 1-propanol as a potential biofuel, metabolic engineering of microorganisms, such as E. coli, has been studied. However, 1-propanol production using metabolically engineered Saccharomyces cerevisiae, which has an amazing ability to produce ethanol and is thus alcohol-tolerant, has infrequently been reported. Therefore, in this study, we aimed to engineer S. cerevisiae strains capable of producing 1-propanol at high levels. RESULTS: We found that the activity of endogenous 2-keto acid decarboxylase and alcohol/aldehyde dehydrogenase is sufficient to convert 2-ketobutyrate (2 KB) to 500 mg/L 1-propanol in yeast...
March 9, 2018: Microbial Cell Factories
Riko Nishimura, Kenji Hata, Eriko Nakamura
Chondrocytes, which are originated from undifferentiated mesenchymal stem cells, play roles in skeletal development and growth in mammal, and smooth movement of joints. Endochondral ossification is necessary for skeletal development, and the multiple and complex biological events are precisely regulated by several hormones, cytokines, and their downstream signaling and transcriptional regulation. On the other hands, articular chondrocytes physiologically retains their features during a lifetime. Numerous molecules involved in endochondral ossification have been identified and investigation of the molecular mechanisms have amazingly progressed...
2018: Clinical Calcium
Xiaoyan Yang, Gongyuan Liu, Yunhao Shi, Wei Huang, Jinjun Shao, Xiaochen Dong
Black phosphorus (BP), emerging as a new member of two-dimensional nanomaterials, has attracted growing research interests for its amazing photoelectric properties and promising application in electronic devices. Recently, BP has been confirmed to be a desirable candidate for phototherapy against cancer, including photothermal therapy (PTT) and photodynamic therapy (PDT). By regulating the number of layers, the bandgap of BP nanosheets (NSs) can be finely tuned to present near infrared light triggered phototherapeutic behaviors...
March 5, 2018: Nanotechnology
Alison M Behie
No abstract text is available yet for this article.
March 1, 2018: Evolutionary Anthropology
Cécilia Gallardo, Bárbara Hufnagel, Célia Casset, Carine Alcon, Fanny Garcia, Fanchon Divol, Laurence Marquès, Patrick Doumas, Benjamin Péret
Cluster root (CR) is one of the most spectacular plant developmental adaptations to hostile environment. It can be found in a few species from a dozen botanical families, including white lupin (Lupinus albus) in the Fabaceae family. These amazing structures are produced in phosphate-deprived conditions and are made of hundreds of short roots also known as rootlets. White lupin is the only crop bearing CRs and is considered as the model species for CR studies. However, little information is available on CRs atypical development, including the molecular events that trigger their formation...
March 1, 2018: Physiologia Plantarum
Mary E Northridge, Sara S Metcalf, Stella Yi, Qiuyi Zhang, Xiaoxi Gu, Chau Trinh-Shevrin
Introduction: While the US health care system has the capability to provide amazing treatment of a wide array of conditions, this care is not uniformly available to all population groups. Oral health care is one of the dimensions of the US health care delivery system in which striking disparities exist. More than half of the population does not visit a dentist each year. Improving access to oral health care is a critical and necessary first step to improving oral health outcomes and reducing disparities...
2018: Frontiers in Public Health
Ying Hao, Wei Li, XingLi Zhou, Fan Yang, ZhiYong Qian
A microneedle (MN) is a micron-sized needle with a height of 10-2000 μm and a width of 10-50 μm, which can penetrate through the epidermis layer to dermal tissue directly without pain. Microneedles are widely used in transdermal drug delivery systems (TDDS) because they are efficient, safe, convenient and painless. Morphologically, microneedles are divided into four types: solid microneedles, coated microneedles, dissolving microneedles, and hollow microneedles. Different types of microneedles play different roles in different research fields...
December 1, 2017: Journal of Biomedical Nanotechnology
Dan Yang, Dechun Liu, Mengmeng Qin, Binlong Chen, Siyang Song, Wenbing Dai, Hua Zhang, Xueqing Wang, Yiguang Wang, Bing He, Xing Tang, Qiang Zhang
Mucus, secreted by the goblet cells of enterocytes, constitutes the first obstacle encountered for the intestinal absorption of nanomedicines. For decades, mucus has simply been regarded as a physical barrier that hinders the permeation and absorption of drugs because of its high viscosity and reticular structure, whereas the interaction of mucus ingredients with nanomedicines is usually neglected. It is unclear whether glycoproteins, as the main components of mucus, interact with nanomedicines. We also do not know how the potential interaction affects the subsequent transportation of nanomedicines through the intestinal epithelium...
February 27, 2018: ACS Applied Materials & Interfaces
Yoshiko Takahashi, Hiroyuki Takeda
No abstract text is available yet for this article.
February 2018: Development, Growth & Differentiation
A Hines, A C Bundy, M Haertsch, M Wallen
AIM: To explore parent's perspective of their child's participation in a magic-themed intervention called Amazing Magic Club (AMC), and to further our understanding of motivated engagement and the impact of themed group-based interventions for children with unilateral cerebral palsy (CP). METHODS: Twenty-nine parents of children with unilateral CP completed semi-structured interviews. The child participants (n = 28) attended one of three AMCs; average age of the children was 10y 6mo (SD 2y 2mo)...
February 26, 2018: Developmental Neurorehabilitation
Ya-Fang Chiu, Bill Sugden
The human tumor viruses that replicate as plasmids* share many features in their DNA synthesis. We know less about their mechanisms of maintenance in proliferating cells but these mechanisms must underlie their partitioning to daughter cells. One amazing implication of how these viruses are thought to maintain themselves is that while host chromosomes commit themselves to partitioning in mitosis, these tumor viruses would commit themselves to partitioning before mitosis and probably in S-phase shortly after their synthesis...
February 21, 2018: Journal of Virology
Edward N Pugh
Vertebrate rod photoreceptors evolved the astonishing ability to respond reliably to single photons. In parallel, the proximate neurons of the visual system evolved the ability to reliably encode information from a few single-photon responses (SPRs) as arising from the presence of an object of interest in the visual environment. These amazing capabilities were first inferred from measurements of human visual threshold by Hecht et al. (1942), whose paper has since been cited over 1,000 times. Subsequent research, in part inspired by Hecht et al...
February 21, 2018: Journal of General Physiology
L Jordaens
Understanding arrhythmias and their treatment is not always easy. The current straightforward approach with catheter ablation and device therapy is an amazing achievement, but does not make management of underlying or other cardiac disease and pharmacological therapy unnecessary. The goal of this paper is to describe how much of the knowledge of the 1980s and early 1990s can and should still be applied in the modern treatment of patients with arrhythmias. After an introduction, this review will focus on paroxysmal atrial fibrillation and a prototype of 'idiopathic' ventricular arrhythmias, two diseases with a striking similarity, and will discuss the arrhythmogenesis...
February 15, 2018: Netherlands Heart Journal
Ankit Kapur
No abstract text is available yet for this article.
February 2018: Canadian Family Physician Médecin de Famille Canadien
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