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simultaneous sequential processing

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https://www.readbyqxmd.com/read/28413698/simultaneous-bilateral-cochlear-implants-developmental-advances-do-not-yet-achieve-normal-cortical-processing
#1
Vijayalakshmi Easwar, Hiroshi Yamazaki, Michael Deighton, Blake Papsin, Karen Gordon
BACKGROUND: Simultaneous bilateral cochlear implantation promotes symmetric development of bilateral auditory pathways but binaural hearing remains abnormal. To evaluate whether bilateral cortical processing remains impaired in such children, cortical activity to unilateral and bilateral stimuli was assessed in a unique cohort of 16 children who received bilateral cochlear implants (CIs) simultaneously at 1.97 ± 0.86 years of age and had ~4 years of CI experience, providing the first opportunity to assess electrically driven cortical development in the absence of reorganized asymmetries from sequential implantation...
April 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28409657/estimates-of-functional-cerebral-hemispheric-differences-in-monolingual-and-bilingual-people-who-stutter-dual-task-paradigm
#2
Myriam Kornisch, Michael P Robb, Richard D Jones
The inter-relationship of stuttering and bilingualism to functional cerebral hemispheric processing was examined on a dual-task paradigm. Eighty native German (L1) speakers, half of whom were sequential bilinguals (L2 = English), were recruited. The participants (mean age = 38.9 years) were organised into four different groups according to speech status and language ability: 20 bilinguals who stutter (BWS), 20 monolinguals who stutter (MWS), 20 bilinguals who do not stutter (BWNS), and 20 monolinguals who do not stutter (MWNS)...
April 14, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28401699/sling-scoop-squirter-anatomical-features-facilitating-prey-transport-processing-and-swallowing-in-rorqual-whales-mammalia-balaenopteridae
#3
Alexander J Werth, Haruka Ito
Much is known about lunge feeding in balaenopterid whales, but many key aspects of structure, function, and behavior have not yet been explained in detail, especially with regard to concentrating, positioning, and swallowing large aggregations of prey. We describe a novel system of three integrated structural components, all of which are involved in sequential feeding activities (intraoral transport, filtration, and swallowing of prey) that follow lunge-feeding engulfment of prey-laden water in rorquals: 1) a hammock-like muscular sling comprising extrinsic lingual musculature along the midline of the ventral pouch; 2) the flattened scoop-like arrangement of caudal-most baleen plates converging in the oropharynx adjacent to the esophageal opening; and 3) a flow-diverting flange at the posterior dorsum of the lip, by a flow channel at the angle of the mouth...
April 12, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28400723/electrophysiological-correlates-of-familiarity-and-recollection-in-associative-recognition-contributions-of-perceptual-and-conceptual-processing-to-unitization
#4
Bingcan Li, Xinrui Mao, Yujuan Wang, Chunyan Guo
It is generally accepted that associative recognition memory is supported by recollection. In addition, recent research indicates that familiarity can support associative memory, especially when two items are unitized into a single item. Both perceptual and conceptual manipulations can be used to unitize items, but few studies have compared these two methods of unitization directly. In the present study, we investigated the effects of familiarity and recollection on successful retrieval of items that were unitized perceptually or conceptually...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28400170/enhanced-simultaneous-saccharification-and-fermentation-of-pretreated-beech-wood-by-in-situ-treatment-with-the-white-rot-fungus-irpex-lacteus-in-a-membrane-aerated-biofilm-reactor
#5
Simone Brethauer, Shahab Robert Lawrence, Studer Michael Hans-Peter
The aim of the present study was to investigate the combination of steam pretreatment and biological treatment with lignin degrading fungal strains in order to enable efficient bioprocessing of beech wood to ethanol. In a sequential process of steam and fungal pretreatment followed by enzymatic hydrolysis, Irpex lacteus almost doubled the glucose yield for mildly pretreated beech wood, but could not improve yields for more severely pretreated substrates. However, when simultaneous saccharification and fermentation is combined with in situ I...
March 18, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28385113/hypoxia-for-msc-expansion-and-differentiation-the-best-way-for-enhancing-tgf%C3%A3-induced-chondrogenesis-and-preventing-calcifications-in-alginate-beads
#6
Christel Henrionnet, Gai Liang, Emilie Roeder, Manuel Dossot, Hui Wang, Jacques Magdalou, Pierre Gillet, Astrid Pinzano
We examined the respective influence of a sequential or a continuous hypoxia during expansion and TGF-ß1-driven chondrogenic differentiation of human bone marrow mesenchymal stem cells (MSCs). The differentiation was performed within alginate beads, a classical tool for the implantation of MSCs within the joint. The standard normoxic 2D (expansion) and 3D (differentiation) MSCs cultures served as reference. In order to determine the quality of the chondrogenesis, we analyzed typical markers such as type II and X collagens, SOX9, COMP, versican, and aggrecan mRNAs using PCR and we assessed the production of type II collagen and HIF-1α by histological stainings...
April 7, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28382639/adaptive-anchoring-model-how-static-and-dynamic-presentations-of-time-series-influence-judgments-and-predictions
#7
Petko Kusev, Paul van Schaik, Krasimira Tsaneva-Atanasova, Asgeir Juliusson, Nick Chater
When attempting to predict future events, people commonly rely on historical data. One psychological characteristic of judgmental forecasting of time series, established by research, is that when people make forecasts from series, they tend to underestimate future values for upward trends and overestimate them for downward ones, so-called trend-damping (modeled by anchoring on, and insufficient adjustment from, the average of recent time series values). Events in a time series can be experienced sequentially (dynamic mode), or they can also be retrospectively viewed simultaneously (static mode), not experienced individually in real time...
April 6, 2017: Cognitive Science
https://www.readbyqxmd.com/read/28362897/distinct-perceptual-rhythms-for-feature-and-conjunction-searches
#8
Laura Dugué, Alice M Xue, Marisa Carrasco
Feature and conjunction searches are widely used to study attentional deployment. However, the spatiotemporal behavior of attention integration in these tasks remains under debate. Are multiple search stimuli processed in parallel or sequentially? Does sampling of visual information and attentional deployment differ between these two types of search? If so, how? We used an innovative methodology to estimate the distribution of attention on a single-trial basis for feature and conjunction searches. Observers performed feature- and conjunction-search tasks...
March 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28357690/reaction-mechanisms-of-dnt-with-hydroxyl-radicals-for-advanced-oxidation-processes-a-dft-study
#9
Yang Zhou, Zhilin Yang, Hong Yang, Chaoyang Zhang, Xiaoqiang Liu
In advanced oxidation processes (AOPs), the detailed degradation mechanisms of a typical explosive of 2,4-dinitrotoluene (DNT) can be investigated by the density function theory (DFT) method at the SMD/M062X/6-311+G(d) level. Several possible degradation routes for DNT were explored in the current study. The results show that, for oxidation of the methyl group, the dominant degradation mechanism of DNT by hydroxyl radicals (•OH) is a series of sequential H-abstraction reactions, and the intermediates obtained are in good agreement with experimental findings...
April 2017: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/28355632/cross-modal-attention-influences-auditory-contrast-sensitivity-decreasing-visual-load-improves-auditory-thresholds-for-amplitude-and-frequency-modulated-sounds
#10
Vivian M Ciaramitaro, Hiu Mei Chow, Luke G Eglington
We used a cross-modal dual task to examine how changing visual-task demands influenced auditory processing, namely auditory thresholds for amplitude- and frequency-modulated sounds. Observers had to attend to two consecutive intervals of sounds and report which interval contained the auditory stimulus that was modulated in amplitude (Experiment 1) or frequency (Experiment 2). During auditory-stimulus presentation, observers simultaneously attended to a rapid sequential visual presentation-two consecutive intervals of streams of visual letters-and had to report which interval contained a particular color (low load, demanding less attentional resources) or, in separate blocks of trials, which interval contained more of a target letter (high load, demanding more attentional resources)...
March 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28346045/a-modular-and-adaptive-mass-spectrometry-based-platform-for-support-of-bioprocess-development-toward-optimal-host-cell-protein-clearance
#11
Donald E Walker, Feng Yang, Joseph Carver, Koman Joe, David A Michels, X Christopher Yu
A modular and adaptive mass spectrometry (MS)-based platform was developed to provide fast, robust and sensitive host cell protein (HCP) analytics to support process development. This platform relies on one-dimensional ultra-high performance liquid chromatography (1D UHPLC) combined with several different MS data acquisition strategies to meet the needs of purification process development. The workflow was designed to allow HCP composition and quantitation for up to 20 samples per day, a throughput considered essential for real time bioprocess development support...
March 27, 2017: MAbs
https://www.readbyqxmd.com/read/28345899/ammonia-borane-dehydrogenation-catalyzed-by-%C3%AE%C2%BA-4-ep3-co-h-ep3-e-ch2ch2pph2-3-e-n-p-and-h2-evolution-from-their-interaction-with-nh-acids
#12
Stefano Todisco, Lapo Luconi, Giuliano Giambastiani, Andrea Rossin, Maurizio Peruzzini, Igor E Golub, Oleg A Filippov, Natalia V Belkova, Elena S Shubina
Two Co(I) hydrides containing the tripodal polyphosphine ligand EP3, (κ(4)-EP3)Co(H) [E(CH2CH2PPh2)3; E = N (1), P (2)], have been exploited as ammonia borane (NH3BH3, AB) dehydrogenation catalysts in THF solution at T = 55 °C. The reaction has been analyzed experimentally through multinuclear ((11)B, (31)P{(1)H}, (1)H) NMR and IR spectroscopy, kinetic rate measurements, and kinetic isotope effect (KIE) determination with deuterated AB isotopologues. Both complexes are active in AB dehydrogenation, albeit with different rates and efficiency...
March 27, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28341739/modifiers-of-prion-protein-biogenesis-and-recycling-identified-by-a-highly-parallel-endocytosis-kinetics-assay
#13
Boris A Ballmer, Rita Moos, Prisca Liberali, Lucas Pelkmans, Simone Hornemann, Adriano Aguzzi
The cellular prion protein, PrP(C), is attached by a glycosylphosphatidylinositol anchor to the outer leaflet of the plasma membrane. Its misfolded isoform PrP(Sc) is the causative agent of prion diseases. Conversion of PrP(C) into PrP(Sc) is thought to take place at the cell surface or in endo-lysosomal organelles. Understanding the intracellular trafficking of PrP(C) may therefore help elucidating the conversion process. Here we describe a time-resolved fluorescence resonance energy transfer (FRET) assay reporting membrane expression and real-time internalization rates of PrP(C) The assay is suitable for high-throughput genetic and pharmaceutical screens for modulators of PrP(C) trafficking...
March 24, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28338829/seeing-is-not-stereotyping-the-functional-independence-of-categorization-and-stereotype-activation
#14
Tiffany A Ito, Silvia Tomelleri
Social categorization has been viewed as necessarily resulting in stereotyping, yet extant research suggests the two processes are differentially sensitive to task manipulations. Here we simultaneously test the degree to which race perception and stereotyping are conditionally automatic. Participants performed a sequential priming task while either explicitly attending to the race of face primes or directing attention away from their semantic nature. We find a dissociation between the perceptual encoding of race and subsequent activation of associated stereotypes, with race perception occurring in both task conditions, but implicit stereotyping occurring only when attention is directed to the race of the face primes...
February 23, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28334667/redox-controlled-release-dynamics-of-thallium-in-periodically-flooded-arable-soil
#15
Svetlana Antić-Mladenović, Tina Frohne, Mirjana Kresović, Hans-Joachim Stärk, Dubravka Savić, Vlado Ličina, Jörg Rinklebe
To our knowledge, this is the first work to mechanistically study the impact of the redox potential (EH) and principal factors, such as pH, iron (Fe), manganese (Mn), dissolved organic carbon (DOC), dissolved inorganic carbon (DIC), chlorides (Cl(-)) and sulfates (SO4(2-)), on the release dynamics of thallium (Tl) in periodically flooded soil. We simulated flooding using an automated biogeochemical microcosm system that allows for systematical control of pre-defined redox windows. The EH value was increased mechanistically at intervals of approximately 100 mV from reducing (-211 mV) to oxidizing (475 mV) conditions...
March 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28297436/simultaneously-integrated-boost-sib-spares-oar-and-reduces-treatment-time-in-locally-advanced-cervical-cancer
#16
Christine H Feng, Yasmin Hasan, Malgorzata Kopec, Hania A Al-Hallaq
We performed a dosimetric comparison of sequential IMRT (sIMRT) and simultaneously integrated boost (SIB) IMRT to boost PET-avid lymph nodes while concurrently treating pelvic targets to determine the potential of SIB IMRT to reduce overall treatment duration in locally advanced cervical cancer. Ten patients receiving definitive radiation therapy were identified retrospectively. RTOG consensus guidelines were followed to delineate the clinical target volume and organs at risk (OAR), which were then expanded per IMRT consortium guidelines to yield the planning target volume (PTV)...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28291787/fast-online-deconvolution-of-calcium-imaging-data
#17
Johannes Friedrich, Pengcheng Zhou, Liam Paninski
Fluorescent calcium indicators are a popular means for observing the spiking activity of large neuronal populations, but extracting the activity of each neuron from raw fluorescence calcium imaging data is a nontrivial problem. We present a fast online active set method to solve this sparse non-negative deconvolution problem. Importantly, the algorithm 3progresses through each time series sequentially from beginning to end, thus enabling real-time online estimation of neural activity during the imaging session...
March 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28270991/joint-alignment-of-multispectral-images-via-semidefinite-programming
#18
Yuanjie Zheng, Yu Wang, Wanzhen Jiao, Sujuan Hou, Yanju Ren, Maoling Qin, Dewen Hou, Chao Luo, Hong Wang, James Gee, Bojun Zhao
In this paper, we introduce a novel feature-point-matching based framework for achieving an optimized joint-alignment of sequential images from multispectral imaging (MSI). It solves a low-rank and semidefinite matrix that stores all pairwise-image feature-mappings by minimizing the total amount of point-to-point matching cost via a convex optimization of a semidefinite programming formulation. This unique strategy takes a complete consideration of the information aggregated by all point-matching costs and enables the entire set of pairwise-image feature-mappings to be solved simultaneously and near-optimally...
February 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28263923/bilingualism-modulates-the-white-matter-structure-of-language-related-pathways
#19
Sini Hämäläinen, Viljami Sairanen, Alina Leminen, Minna Lehtonen
Learning and speaking a second language (L2) may result in profound changes in the human brain. Here, we investigated local structural differences along two language-related white matter trajectories, the arcuate fasciculus and the inferior fronto-occipital fasciculus (IFOF), between early simultaneous bilinguals and late sequential bilinguals. We also examined whether early exposure to two languages might lead to a more bilateral structural organization of the arcuate fasciculus. Fractional anisotropy, mean and radial diffusivities (FA, MD, and RD respectively) were extracted to analyse tract-specific changes...
March 2, 2017: NeuroImage
https://www.readbyqxmd.com/read/28262560/bliss-a-bioorthogonal-dual-labeling-strategy-to-unravel-lignification-dynamics-in-plants
#20
Cedric Lion, Clémence Simon, Brigitte Huss, Anne-Sophie Blervacq, Louis Tirot, Djadidi Toybou, Corentin Spriet, Christian Slomianny, Yann Guerardel, Simon Hawkins, Christophe Biot
A better in vivo understanding of lignin formation within plant cell walls will contribute to improving the valorization of plant-derived biomass. Although bioorthogonal chemistry provides a promising platform to study the lignification process, methodologies that simultaneously detect multiple chemical reporters in living organisms are still scarce. Here, we have developed an original bioorthogonal labeling imaging sequential strategy (BLISS) to visualize and analyze the incorporation of both p-hydroxyphenyl (H) and guaiacyl (G) units into lignin in vivo with a combination of strain-promoted and copper-catalyzed azide-alkyne cycloadditions...
March 16, 2017: Cell Chemical Biology
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