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https://www.readbyqxmd.com/read/29473522/an-evidence-based-review-of-off-label-uses-of-polidocanol
#1
Hossein Babaei, Elgar Enamzadeh
BACKGROUND: Polidocanol is approved for its competence in treatment of varicose veins and spider veins; however, unfortunately, many of its off-label uses are still underappreciated. OBJECTIVE: Lack of an appropriate comprehensive review for off-label uses of this medication troubles physicians about making evidence-based decisions on prescribing it for its various outstanding off-label uses. This article attempts to provide physicians with the latest information concerning successful and unsuccessful use of polidocanol as an alternative treatment for esophageal and gastric varices, tendinopathy and epicondylitis, vascular malformations, varicocele, hydrocele and spermatocele, aneurysmal bone cysts, itching, management of gastrointestinal bleeding, simple renal cysts, reducing the incidence and severity of radio-induced dermatitis, and hemorrhoids...
February 23, 2018: Current Clinical Pharmacology
https://www.readbyqxmd.com/read/29468068/a-case-report-of-thrombosed-varicosities-of-pubic-collateral-veins-ideal-treatment-strategy-and-contribution-of-era-imaging-technologies-in-diagnosis
#2
Daniel Paramythiotis, Patroklos Goulas, Petros Bangeas, Argiris Giannopoulos, Kostantinos Kapoulas, Vasileios Rafailidis, Georgios Papadopoulos, Kiriakos Ktenidis, Anna Kalogera-Fountzila, Antonis Michalopoulos
Collateral circulation is an alternative path occurring in case of venous or artery obstruction. This path may usually develop after primary recanalization. In our case, a 62-year-old woman presented to our Emergency Department complaining about a suprapubic swelling with a cyanotic discoloration of the overlying skin for the past 10 days for which she had been previously prescribed antibiotics. Investigation with ultrasound and contrast-enhanced computed tomography was performed. An imaging study revealed thrombosed pubic varicose collateral veins due to deep vein obstruction and occlusion of the left external iliac vein...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29462021/review-of-endovenous-thermal-ablation-of-the-great-saphenous-vein-endovenous-laser-therapy-versus-radiofrequency-ablation
#3
Omeed Ahadiat, Shauna Higgins, Alexandre Ly, Azadeh Nazemi, Ashley Wysong
BACKGROUND: Endovenous thermal ablation is a popular treatment for varicose veins of the greater saphenous vein. Two common techniques of thermal ablation are endovenous laser therapy (EVLT) and radiofrequency ablation (RFA). OBJECTIVE: The authors compare EVLT and RFA in vein therapy. METHODS: A review was conducted using PubMed. Studies comparing the treatment modalities were gathered and compared on the basis of 5 main standpoints, including: efficacy, side effects, serious complications, recurrence, and quality of life...
February 15, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29452831/painless-urethral-bleeding-during-penile-erection-in-an-adult-man-with-klippel-trenaunay-syndrome-a-case-report
#4
Hongen Lei, Xing Guan, Hu Han, Xiaosong Qian, Xiaoguang Zhou, Xiaodong Zhang, Long Tian
INTRODUCTION: Klippel-Trenaunay syndrome (KTS) is a rare congenital vascular disorder characterized by a triad of cutaneous port wine capillary malformations, varicose veins, and hemihypertrophy of bone and soft tissues. AIMS: To report on a rare case of KTS in an adult man manifested by painless urethral bleeding during penile erection briefly review the clinical presentation and management of the genitourinary forms of this syndrome. METHODS: On presentation, the clinical features of this patient, including medical history, signs and symptoms, and imaging examinations, were recorded...
February 13, 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29442615/endovenous-varicose-vein-treatment-in-patients-with-right-heart-failure-and-tricuspid-valve-regurgitation-a-relative-contraindication
#5
Katherine Hulme, Thodur Vasudevan
No abstract text is available yet for this article.
March 2018: Phlebology
https://www.readbyqxmd.com/read/29439934/suppressed-networks-of-inflammatory-mediators-characterize-chronic-venous-insufficiency
#6
Ulka Sachdev, Lena Vodovotz, Julie Bitner, Derek Barclay, Ruben Zamora, Jinling Yin, Richard L Simmons, Yoram Vodovotz
OBJECTIVE: Chronic venous insufficiency (CVI) affects 25 million adults in the United States. Little emphasis has been placed on inflammatory changes associated with CVI. We hypothesize that in patients with early to mid-stage benign varicose vein disease, differences in circulating inflammatory mediators will be manifested in blood draining the involved area vs circulating blood in control subjects. METHODS: Patients undergoing either endovenous ablation or sclerotherapy for Clinical, Etiology, Anatomy, and Pathophysiology clinical class 3 to 5 disease underwent phlebotomy from regional veins at the time of the procedure...
February 10, 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29439933/a-national-survey-on-management-of-varicose-veins-in-china
#7
Mingyi Zhang, Tao Qiu, Xiaoqing Bu, Xiangtao Li, Gangzhu Liang, Huan Zhang, Luyuan Niu, Hui Zhao, Fuxian Zhang
OBJECTIVE: This study aimed to investigate the current clinical practice and management strategies for varicose veins among Chinese physicians in general and in specific case vignettes. METHODS: A questionnaire survey was conducted among 726 Chinese physicians who were attending the vascular surgery academic conferences during August 2016 to May 2017 in China. Physicians were eligible if they were familiar with several currently used treatment techniques for varicose veins...
February 10, 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29434428/evaluation-of-endovenous-laser-ablation-for-varicose-veins-using-a-computer-simulation-model-secondary-publication
#8
REVIEW
Hisanao Hazama, Masato Yoshimori, Norihiro Honda, Kunio Awazu
Background and aims: Endovenous laser ablation (EVLA) has been well-reported as a minimally invasive method to deal with varices of the lower extremities. The lasers used fall into two categories: pigment, i.e., hemoglobin-specific lasers in the visible and near-infrared (near-IR) wavebands and longer wavelength mid-infrared lasers where the chromophore is water. The fiber used to deliver the laser energy is also important, and not enough attention has been paid to this element of EVLA...
December 31, 2017: Laser Therapy
https://www.readbyqxmd.com/read/29434272/modified-inguinal-microscope-assisted-varicocelectomy-under-local-anesthesia-a-non-randomised-controlled-study-of-3565-cases
#9
Jin Wang, Qian Liu, Xun Wang, Rijian Guan, Sen Li, Youpeng Zhang, Yongbiao Cheng, Hanqing Zeng, Yong Tang, Zhaohui Zhu
Varicocele is a common abnormality, but the conventional microsurgical subinguinal varicocelectomy (CMSV) has some disadvantages. We invented Modified Inguinal Microscope-Assisted Varicocelectomy (MIMV) under local anesthesia. This study aims to evaluate MIMV by comparing it to CMSV in operating duration, time to return to normal activity, postoperative complications, achievement of natural pregnancy and improvement of semen quality for patients with infertility, pain score for those with scrotal pain, and so on...
February 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29431010/commentary-on-pelvic-venous-reflux-in-males-with-varicose-veins-and-recurrent-varicose-veins
#10
Melvin Rosenblatt
No abstract text is available yet for this article.
January 1, 2018: Phlebology
https://www.readbyqxmd.com/read/29428536/prospective-comparison-of-effect-of-ligation-and-foam-sclerotherapy-with-foam-sclerotherapy-alone-for-varicose-veins
#11
Xin Li, Bo Yang, Xianlun Li, Shiyan Ren
PURPOSE: To compare the efficacy of ligation after foam sclerotherapy (FSL) with foam sclerotherapy (FS) alone for patients with varicose veins prospectively. METHODS: Ninety-four patients with varicose veins underwent foam sclerothrapy alone and eighty-eight patients with varicose veins received ligation after foam sclerotherapy. Patients were followed up at 1, 3, 6 and 12 months after treatment. The postoperative complications were documented prospectively. RESULTS: In comparison with patients underwent FSL, patients treated with FS only had higher incidence of phlebitis within 4 weeks (14...
February 8, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29428534/midterm-result-of-endovascular-treatment-for-iliac-vein-compression-syndrome-from-a-single-center
#12
Chongqing Huang, Guanfeng Yu, Jingyong Huang
OBJECTIVE: To investigate the clinical effect of endovascular interventional treatment for iliac vein compression syndrome (IVCS). MATERIAL AND METHODS: The data of 68 patients with IVCS, underwent interventional treatment in our hospital, were analyzed retrospectively. Among these patients, 46 were complicated with lower extremity varicose veins. 65 patients underwent stent implantation, while 3 patients underwent simple balloon angioplasty. 14 patients were complicated with post-thrombotic syndrome (PTS) and 11patients with acute deep venous thrombosis (DVT)...
February 8, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29427797/severe-lower-limb-cellulitis-defining-the-epidemiology-and-risk-factors-for-primary-episodes-in-a-population-based-case-control-study
#13
Jeffrey Cannon, Gawri Rajakaruna, John Dyer, Jonathan Carapetis, Laurens Manning
OBJECTIVE: To describe the epidemiology and risk factors for primary episodes of severe lower leg cellulitis (LLC). METHODS: A longitudinal cohort study using state-wide data linkage of adults presenting to Western Australian (WA) hospitals with a first ever LLC from January 2002 to December 2013. To determine risk factors, medical records from the index patient, together with comparable data from controls matched by age, sex, postcode and month of admission were extracted...
February 7, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29424318/the-significance-of-pain-in-chronic-venous-disease-and-its-medical-treatment
#14
Djordje Radak, Igor Atanasijevic, Mihailo Neskovic, Esma Isenovic
Chronic venous disease (CVeD) is a highly prevalent condition in the general population, and it has a significant impact on quality of life. While it is usually manifested by obvious signs, such as varicose veins and venous ulcers, other symptoms of the disease are less specific. Among the other symptoms, which include heaviness, swelling, muscle cramps and restless legs, pain is the symptom that most frequently compels CVeD patients to seek medical aid. However, there is a substantial discrepancy between pain severity and clinically detectable signs of CVeD, questioned by several opposing studies...
February 8, 2018: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29421005/systematic-review-and-meta-analysis-of-endovascular-and-surgical-revascularization-for-patients-with-chronic-lower-extremity-venous-insufficiency-and-varicose-veins
#15
Sreekanth Vemulapalli, Kishan Parikh, Remy Coeytaux, Victor Hasselblad, Amanda McBroom, Abigail Johnston, Giselle Raitz, Matthew J Crowley, Kathryn R Lallinger, W Schuyler Jones, Gillian D Sanders
BACKGROUND: Chronic lower extremity venous disease (LECVD) is twice as prevalent as coronary heart disease, and invasive therapies to treat LECVD accounted for an estimated $290 million in Medicare expenditures in 2015. Despite increasing use of these invasive therapies, their comparative effectiveness is unknown. METHODS: We conducted a systematic review and meta-analysis of treatments for patients (symptomatic and asymptomatic) with lower extremity varicosities and/or lower extremity chronic venous insufficiency/incompetence/reflux...
February 2018: American Heart Journal
https://www.readbyqxmd.com/read/29412077/transient-effects-of-anesthesia-on-leukocyte-apoptosis-and-monocyte-cytokine-stimulation-a-clinical-study
#16
Paraskevi Matsota, Georgia Kostopanagiotou, Konstantinos Kalimeris, Ageliki Pandazi, Antigone Kotsaki, Styliani Kontogiannopoulou, Evangelos J Giamarellos-Bourboulis
The effects of anesthetics on immune cell apoptosis and cytokine stimulation were studied in a prospective study. American Society of Anesthesiologists I/II patients underwent elective inguinal hernia repair or varicose veins stripping surgery and were randomized to either epidural anesthesia (n = 14) or general anesthesia with sevoflurane (n = 19) or propofol (n = 15). Blood was sampled before anesthesia induction (T0), at the end of surgery (T1), and 6 h later (T2). Apoptosis was determined by ANNEXIN-V staining of white blood cells; monocytes were isolated and stimulated for cytokine production...
February 7, 2018: Immunological Investigations
https://www.readbyqxmd.com/read/29402614/tissue-plasminogen-activator-to-treat-a-stroke-after-foam-sclerotherapy-in-a-woman-with-a-patent-foramen-ovale
#17
Kosuke Matsuzono, Naoto Arai, Masayuki Suzuki, Younhee Kim, Tadashi Ozawa, Takafumi Mashiko, Haruo Shimazaki, Reiji Koide, Tohru Matsuura, Shigeru Fujimoto
Although foam sclerotherapy to varicose veins is now a popular treatment because of its high efficacy and safety, some neurologic complications have recently been reported. Presently, the effectiveness and safety of intravenous recombinant tissue-type plasminogen activator therapy to stroke following foam sclerotherapy remain unclear. Here, we report the case of a 68-year-old woman whose ischemic symptoms following foam sclerotherapy were treated by intravenous recombinant tissue-type plasminogen activator...
February 2, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29398312/implementation-of-a-virtual-vascular-clinic-with-point-of-care-ultrasound-in-an-integrated-health-care-system
#18
Judith C Lin, Janelle M Crutchfield, Dana K Zurawski, Courtney Stevens
OBJECTIVE: Using secured videoconferencing technologies, telemedicine may replace traditional clinic visits, save patients' time and travel, and improve use of limited surgeon and facility resources. We report our initial experience of the remote clinical encounter (RCE) by evaluating vascular surgery patients. METHODS: In this proof-of-concept pilot study, we conducted telemedicine evaluations of vascular patients at a tertiary care institution from October 2015 to August 2016...
February 1, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29385790/recurrent-varices-after-surgery-revas-a-clinical-and-color-doppler-ultrasound-scan-analysis
#19
Daniele Bissacco, Enza L Castronovo, Silvia Romagnoli, Maurizio Domanin
BACKGROUND: To evaluate clinical pictures, symptoms and etiology of Recurrent Varices After Surgery (REVAS) through a clinical and color-Doppler-ultrasound scan (CDUS) analysis. METHODS: During a three-year period, data about 9043 consecutive outpatients were collected. Among these, 160 patients (1.8%) were affected by REVAS. Data about risk factors, types of primary vein surgery, symptomatology, clinical and CDUS characteristics were analyzed using the Clinical, Etiology, Anatomy and Pathophysiology (CEAP), Stonebridge and Perrin classifications in order to evaluate clinical and anatomical varices patterns...
January 29, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29378357/predictors-of-post-thrombotic-ulcer-after-acute-dvt-the-riete-registry
#20
Jean-Philippe Galanaud, Laurent Bertoletti, Maria Amitrano, Carmen Fernández-Capitán, José María Pedrajas, Vladimir Rosa, Manuel Barrón, Alicia Lorenzo, Olga Madridano, Isabelle Quéré, Susan R Kahn, Paolo Prandoni, Manuel Monreal
In patients with deep-vein thrombosis (DVT) in the lower limbs, venous ulcer is the most debilitating and end-stage clinical expression of the post-thrombotic syndrome (PTS). To date, risk factors for PTS-related ulcer in DVT patients have not been identified.We used the international observational RIETE registry to assess the evolution of PTS signs and symptoms during a 3-year follow-up period and to identify independent predictors of PTS ulcer at 1 year in patients with acute DVT.Among 1,866 eligible patients, cumulative rates of PTS ulcer at 1, 2 and 3 years were 2...
February 2018: Thrombosis and Haemostasis
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