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https://www.readbyqxmd.com/read/29677415/acute-ischemic-stroke-in-a-young-woman-with-no-known-risk-factors
#1
Noureldin Abdelhamid, Salman Farooq, Amrou Sarraj
INTRODUCTION: We aim to highlight a potentially morbid consequence of foam-sclerotherapy for the treatment of varicose veins. CASE REPORT: We report a case of a 41-year-old woman with no significant medical history who presented to the emergency department with sudden onset of focal neurologic deficits. She had undergone varicose vein treatment with foam sclerotherapy 2 days prior. Magnetic resonance imaging of the brain showed acute cerebellar infarct. Computed tomography angiography was unremarkable...
March 2018: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29671380/removal-of-benign-superficial-masses-using-the-trivex-system-preliminary-clinical-results
#2
Sheng-Jun Duan, Run-Zhu Jiang, Ying-Xin Zhang, Hua-Shui Liu, Nai-Shun Zhang, Shi-Ye Zhang
BACKGROUND AND OBJECTIVE: Transilluminated powered phlebectomy using the TriVex system is a new procedure for minimally invasive varicose vein surgery. We used the TriVex system for the removal of benign superficial subcutaneous soft tissue masses, and we also achieved satisfactory clinical effects. The objective of this study was to explore the feasibility, benefits, and technique-related complications of using the TriVex system for the removal of benign superficial masses as a novel and minimally invasive surgical technique...
April 1, 2018: Surgical Innovation
https://www.readbyqxmd.com/read/29660929/ecchymosis-a-novel-sign-in-patients-with-varicose-veins
#3
Ertan Yetkin, Mehmet Ileri, Johannes Waltenberger
BACKGROUND: In the absence of trauma, hematologic disease and anti-platelet use, no attention has been paid to elucidate the mechanism of ecchymosis. It has taken our attention that ecchymosis on lower limb might be a sign of varicose vein. Accordingly, we aimed to analyze and describe the frequency of leg symptoms and presence of ecchymosis in patients with varicose vein. MATERIALS AND METHODS: Four hundred and ninety four patients who had been diagnosed as having varicose vein or chronic venous insufficiency either by clinical examination or Doppler ultrasonography were included in the study...
2018: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/29660117/polymorphisms-of-genes-involved-in-inflammation-and-blood-vessel-development-influence-the-risk-of-varicose-veins
#4
A Shadrina, Y Tsepilov, M Smetanina, E Voronina, E Seliverstov, E Ilyukhin, A Kirienko, I Zolotukhin, M Filipenko
Heredity plays an important role in the etiology of varicose veins (VVs). However, the genetic basis underlying this condition remains poorly understood. Our aim was to replicate top association signals from genome-wide association studies (GWAS) for VVs of lower extremities using two independent datasets - our sample of ethnic Russian individuals (709 cases and 278 controls) and a large cohort of British residents from UK Biobank (10,861 cases and 397,594 controls). Associations of polymorphisms rs11121615, rs6712038, rs507666, rs966562, rs7111987, rs6062618, and rs6905288 were validated in the UK Biobank individuals at a Bonferroni-corrected significance level...
April 16, 2018: Clinical Genetics
https://www.readbyqxmd.com/read/29652086/five-year-follow-up-of-a-randomized-clinical-trial-comparing-open-surgery-foam-sclerotherapy-and-endovenous-laser-ablation-for-great-saphenous-varicose-veins
#5
S Vähäaho, K Halmesmäki, A Albäck, E Saarinen, M Venermo
BACKGROUND: New treatment methods have challenged open surgery as a treatment for great saphenous vein (GSV) insufficiency, the most common being ultrasound-guided foam sclerotherapy (UGFS) and endovenous laser ablation (EVLA). This study evaluated the long-term results of surgery, EVLA and UGFS in the treatment of GSV reflux. METHODS: Patients with symptomatic GSV reflux were randomized to undergo either open surgery, EVLA or UGFS. The main outcome measure was the occlusion rate of the GSV at 5 years after operation...
May 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29642798/a-retrospective-study-of-a-new-n-butyl-2-cyanoacrylate-glue-ablation-catheter-incorporated-with-application-guiding-light-for-the-treatment-of-venous-insufficiency-twelve-month-results
#6
Turhan Yavuz, Altay Nihat Acar, Huseyin Aydın, Evren Ekingen
Objective This study aims to present the early results of a retrospective study of the use of novel n-butyl-2-cyanoacrylate (VenaBlock)-based nontumescent endovenous ablation with a guiding light for the treatment of patients with varicose veins. Methods Patients with lower limb venous insufficiency were treated with n-butyl-2-cyanoacrylate (VenaBlock Venous Closure System) between April 2016 and July 2016. The study enrolled adults aged 21-70 years with symptomatic moderate to severe varicosities (C2-C4b) and great saphenous vein reflux lasting longer than 0...
January 1, 2018: Vascular
https://www.readbyqxmd.com/read/29628617/varicose-veins-and-lower-extremity-venous-insufficiency
#7
REVIEW
Eric DePopas, Matthew Brown
Lower extremity venous insufficiency and varicose veins are common conditions, affecting up to 25% of women. Herein, we review the pathophysiology of lower extremity venous insufficiency and varicose veins, the epidemiology of varicose veins, clinical diagnosis, and ultrasonographic diagnosis. We also discuss treatment rationale, algorithms, and techniques, with a focus on endovenous great saphenous vein ablation.
March 2018: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/29628609/management-of-chronic-deep-vein-thrombosis-in-women
#8
REVIEW
Rulon L Hardman
Chronic deep vein thrombosis (DVT) affects hundreds of thousands of women in the United States. Chronic DVT can lead to pain, edema, venous ulcers, and varicosities. While there are limited data regarding the management of chronic DVT, several interventional radiology groups aggressively treat chronic DVT to aid patient symptom resolution. Recanalization of occluded veins and venous stenting re-establishes deep vein flow and decreases venous hypertension.
March 2018: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/29616754/venous-insufficiency-differences-in-the-content-of-trace-elements-a-preliminary-report
#9
Agnieszka Rusak, Ewa Karuga-Kuźniewska, Benita Wiatrak, Maria Szymonowicz, Mateusz Stolarski, Małgorzata Radwan-Oczko, Rafał J Wiglusz, Paweł Pohl, Zbigniew Rybak
BACKGROUND: Venous insufficiency is still a serious clinical problem. The exact cause and molecular mechanisms of this disease are still unknown. In this study, we try to identify whether there is a difference in the level of trace elements between healthy and pathological veins. Our results show that insufficient veins have different levels of some trace elements: magnesium, calcium, manganese, and silicon compared to control samples. This study could lead to a better understanding of the molecular causes of venous insufficiency and may help to develop better methods of treatment...
April 4, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29588300/episodes-of-extreme-lower-leg-pain-caused-by-intraosseous-varicose-veins
#10
Elisa S Rezaie, Mario Maas, Chantal M A M van der Horst
We present a case of a 67-year-old man with episodes of extreme pain of the right lower extremity that prevented him from walking and sleeping. The patient had a history of varices in both legs. Physical examination showed a pretibial varix of the right leg inferiorly from a painful spot. X-ray of the right lower leg showed a cortex disruption at this spot. MRIs confirmed the disruption of the cortex of the right tibia and demonstrated an intraosseous vessel. The diagnosis intraosseous varices was made and the vein was surgically resected...
March 27, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29582749/is-radiofrequency-ablation-of-varicose-veins-a-valuable-option-a-systematic-review-of-the-literature-with-a-cost-analysis
#11
Thomas G Poder, Jean-François Fisette, Suzanne K Bédard, Marc-Antoine Despatis
BACKGROUND: Since the 1990s, new techniques for the treatment of varicose veins have emerged, including radiofrequency ablation (RFA) and laser treatment. We performed a study to compare the safety, efficacy and outcomes of RFA compared to those of open surgery and laser ablation for the treatment of varicose veins. We also carried out a cost analysis of RFA compared to open surgery to assess whether RFA could help free up operating room time by being performed in an outpatient context...
April 2018: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/29577902/identification-of-aberrant-circular-rna-expression-and-its-potential-clinical-value-in-primary-great-saphenous-vein-varicosities
#12
Wan Zhang, Li Li, Yi Si, Zhenyu Shi, Ting Zhu, Shunjiu Zhuang, Weiguo Fu
This study aimed to identify aberrant circRNA expression in primary great saphenous vein varicosities (PGSVVs) and investigate its potential clinical significance. High-throughput sequencing was applied to analyze the differential expression of circRNAs in three paired vein samples of PGSVVs and a control group. Computational bioinformatics analyses, including gene ontology (GO) analysis and encyclopedia of genes and genomes (KEGG) pathway analysis, were performed to further enrich microRNA data. Real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR) was used to verify the selected aberrant circRNAs in all vein samples, and a receiver operating characteristic (ROC) curve was plotted to evaluate the diagnostic and potential clinical significance...
March 22, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29572099/a-ten-year-analysis-of-the-reasons-for-death-following-ambulatory-surgery-nine-closed-claims-declared-to-sham-insurance
#13
A Theissen, F Fuz, M Bouregba, M Autran, M Beaussier
INTRODUCTION: The constant development of ambulatory surgery (AS) raises the problem of monitoring patients after discharge and the risk of death in the case of delays in the management of a serious complication. PATIENTS AND METHODS: The aim of this retrospective study was to describe the deaths observed within the 30-day period following AS declared to the SHAM insurance (Société Hospitalière d'Assurance Mutuelle) over the last 10 years. RESULTS: During the study period 33,962 claims were surgery-related and 11 were for deaths after AS...
March 20, 2018: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/29551506/genome-wide-association-study-in-ethnic-russians-suggests-an-association-of-the-mhc-class-iii-genomic-region-with-the-risk-of-primary-varicose-veins
#14
Alexandra Shadrina, Yakov Tsepilov, Ekaterina Sokolova, Mariya Smetanina, Elena Voronina, Eugene Pakhomov, Kseniya Sevost'ianova, Andrey Shevela, Evgeny Ilyukhin, Evgeny Seliverstov, Igor Zolotukhin, Maxim Filipenko
Heredity is a well-known risk factor for varicose veins, but genetic basis of this condition remains poorly studied. Our aim was to conduct a large-scale genetic association study for primary varicose veins (PVVs) in the population of ethnic Russians. An initial scan using Illumina HumanExome-12 v1.0 BeadChip was performed for 273 patients with PVVs and 250 controls without a history of chronic venous disease and other venous disorders. After quality control and removal of monomorphic markers, 25,424 common and 48,232 rare variants were included in the analysis...
March 15, 2018: Gene
https://www.readbyqxmd.com/read/29538571/overweight-in-rural-elderly-association-with-health-conditions-and-quality-of-life
#15
Darlene Mara Dos Santos Tavares, Alisson Fernandes Bolina, Flavia Aparecida Dias, Pollyana Cristina Dos Santos Ferreira, Nilce Maria de Freitas Santos
This study aimed to verify the association of overweight with functional disability, self-reported morbidities and quality of life (QoL) among rural elderly dwellers. This is a domestic and cross-sectional survey conducted in the rural region of a municipality of Southeast Brazil. Three hundred seventy non-overweight elderly people and 192 overweight elderly people were evaluated with the following tools: semi-structured; Katz and Lawton and scales; World Health Organization Quality of Life - BREF and World Health Organization Quality of Life Assessment for Older Adults...
March 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29531879/clinical-tests-combined-with-color-doppler-versus-color-doppler-alone-in-identifying-incompetent-perforator-veins-of-the-lower-limb-a-prospective-analytical-study
#16
Sathasivam Sureshkumar, Narayan Vignesh, J Venkatachalam, Chellappa Vijayakumar, Sundaramurthi Sudharsanan
Background The color Doppler, a better investigation to identify the perforators objectively has replaced the clinical examination for the same. However, this has led to a significant number of negative explorations and cosmetic disfigurement. Objective To compare the efficacy of the clinical tests combined with the color Doppler versus color Doppler alone to identify the perforator incompetence during the surgery for primary varicose veins of the lower limb. Methods This was a prospective analytical study, including 61 lower limb varicose vein patients who belonged to the Clinical-Etiology-Anatomy-Pathophysiology (CEAP) class four-six, planned for the surgical treatment for perforator incompetence, excluding those requiring additional vascular or nonvascular procedure, recurrent varicose veins and those who had injection sclerotherapy prior to the surgery...
January 5, 2018: Curēus
https://www.readbyqxmd.com/read/29515702/mid-term-report-on-the-safety-and-effectiveness-of-endovenous-radiofrequency-ablation-for-varicose-veins
#17
Kiyoshi Tamura, Toshiyuki Maruyama
Objective : Endovenous radiofrequency ablation (RFA), a relatively new technique for treating great saphenous varicose veins, is less invasive compared with stripping surgery. This study examined the mid-term safety and effectiveness of RFA for varicose veins. Materials and Methods : We enrolled 104 patients (147 limbs) who underwent RFA for varicose veins of the lower extremities (females, 67; 64.4%). The mean age was 68.9±9.2 years (39-85 years). In 121 limbs (82.3%), there were great saphenous veins. All patients were observed as outpatients for 12 months after the procedure...
December 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29515697/asymptomatic-isolated-calf-deep-vein-thrombosis-does-it-worsen-after-varicose-vein-surgery
#18
Sadaaki Horiguchi, Hisako Ono, Hiroyuki Shirato, Toshimitsu Kawakami, Shiho Yabuki, Naomi Morita, Nozomu Shirasugi
In our varicose vein center, on a trial basis, among the patients with asymptomatic calf deep vein thrombosis (CDVT) we carefully selected the patients for varicose vein surgery using the requirements as follows; 1) the patients had varicose veins with incompetent saphenous veins, 2) sequential examination including DUS confirmed stability and clinical insignificance of asymptomatic CDVT, 3) the patients do not have any risk factors for DVT such as a coagulation profile disorder (antithrombin deficiency, protein C deficiency, protein S deficiency, or antiphospholipid syndrome) or malignancies, 4) surgery is possible under local anesthesia alone, and 5) the patients can understand the concept of asymptomatic CDVT and undergo the surgery on their own will and informed consent...
December 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29502781/liquid-and-foam-sclerotherapy-for-spider-and-varicose-veins
#19
REVIEW
Kathleen Gibson, Krissa Gunderson
Sclerotherapy has wide applicability in treating venous disease at every stage of clinical disease. The various sclerosant drugs and formulations each have unique properties, utilities, and side effects. Treating physicians should be aware of the differences between agents, accounting for disease presentation, vein characteristics, and patient comorbidities when selecting the appropriate sclerosing agents. Successful outcomes rely on proper patient evaluation and assessment for contraindications to sclerotherapy...
April 2018: Surgical Clinics of North America
https://www.readbyqxmd.com/read/29502780/phlebectomy-techniques-for-varicose-veins
#20
REVIEW
Daniel F Geersen, Cynthia E K Shortell
Ambulatory phlebectomy is a well-known and widely used procedure for residual symptomatic venous disease. Tumescent anesthesia complements the procedure, providing the ability to perform this intervention in a wide range of practice settings. The procedures are well tolerated by most patients, and complications are rare. They include venous thromboembolism, infection, and hematoma and are generally simple to manage. Alternative and emerging techniques of powered phlebectomy and cyanoacrylate glue are providing alternative forms for treatment and will advance the practice further...
April 2018: Surgical Clinics of North America
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