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Behcet disease

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https://www.readbyqxmd.com/read/28644825/neuro-beh%C3%A3-et-s-disease-in-peru-a-case-report-and-literature-review
#1
Roberto A Molina, Andrely Huerta-Rosario, Carlos Alexander Alva Díaz, Koni Katerin Mejía Rojas, Nicanor Mori, Roberto Romero Sánchez
Behçet's disease is a vasculitis that can cause inflammatory lesions in multiple organs or systems including the nervous system. Most cases worldwide have been reported along what is called the "Silk Route" from the Mediterranean region to Japan, so it is considered a rare disease in Latin American countries. The frequency of neurological involvement ranges from 5 to 13%. We present the case of a young adult woman with diagnostic criteria for Behçet's disease and manifestations of neurological disease, as well as a review of the literature...
June 20, 2017: Medwave
https://www.readbyqxmd.com/read/28642788/comparison-between-intestinal-beh%C3%A3-et-s-disease-and-crohn-s-disease-in-characteristics-of-symptom-endoscopy-and-radiology
#2
Tianyu Zhang, Liwen Hong, Zhengting Wang, Rong Fan, Maochen Zhang, Yun Lin, Mengmeng Cheng, Xiaolin Zhou, Peijun Sun, Xiaoyi Lin, Jie Zhong
AIM: To evaluate different parameters in differentiating intestinal BD from CD. METHODS: The medical records of inpatients with intestinal BD and CD were retrospectively reviewed. The univariate value of different parameters was analyzed, respectively. A differentiation model was established by pooling all valuable parameters together. Diagnostic efficacy was evaluated, and a receiver operating curve (ROC) was plotted. RESULTS: Forty-two BD patients and ninety-seven CD patients were reviewed...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28640657/retinal-findings-on-oct-in-systemic-conditions
#3
Preeti Patil Chhablani, Vikas Ambiya, Akshay G Nair, Sailaja Bondalapati, Jay Chhablani
PURPOSE: Imaging technology has advanced by leaps and bounds in the recent past and has resulted in a much greater understanding of ocular diseases. The aim of this review article is to summarize optical coherence tomography (OCT) findings of various systemic conditions. METHOD: A systematic literature search of the Medline/PubMed database was performed. English articles up to April 2015 were included. Terms used for search included: Alzheimer's Disease; Multiple Sclerosis; Parkinson's Disease; Behçet's Disease; Schizophrenia; Migraine; Obstructive Sleep Apnea Syndrome; Neurofibromatosis; Sickle Cell Disease; Renal diseases; Lupus Retinopathy; Valsalva Retinopathy; Whiplash Retinopathy; Shaken-Baby Syndrome; Choroidal metastases; Intracranial Hypertension; Drug toxicity; Deferoxamine; Sildenafil; Tamoxifen; Hydroxychloroquine; Chloroquine; Ethambutol; Lead; Sickle Cell Disease; and Thalassemia along with OCT...
June 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28638685/carotid-artery-stiffness-in-beh%C3%A3-et-s-disease
#4
Servet Yolbaş, Nevzat Gözel, Mustafa Necati Dağlı, Süleyman Serdar Koca, Emir Dönder
OBJECTIVE: Increased carotid arterial stiffness (CAS) is a predictor of subclinical early atherosclerosis as well as carotid intima-media thickness (cIMT). We aimed to determine CAS and cIMT in Behçet's disease (BD). MATERIAL AND METHODS: BD (n=49) and rheumatoid arthritis (RA) (n=64) patients and healthy controls (HC) (n=40) were included in the study. cIMT was measured. CAS indices, including arterial compliance (AC), arterial distensibility (AD), Young's elastic modulus (YEM), Peterson's elastic modulus (Ep), and β stiffness index (βSI) were measured based on the diameter-pressure relationship...
June 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28638683/low-prevalence-of-obesity-in-beh%C3%A3-et-s-disease-is-associated-with-high-obestatin-level
#5
Süleyman Serdar Koca, Murat Kara, Metin Özgen, Ramazan Dayanan, Caner Feyzi Demir, Kader Aksoy, Nevin İlhan, Emir Dönder, Ahmet Işık
OBJECTIVE: Chronic inflammatory diseases are associated with altered body composition. Ghrelin has anti-inflammatory effects, and its level is altered in obesity and inflammatory diseases. The aim of the study was to evaluate the prevalence of obesity and ghrelin and obestatin levels in patients with Behçet's disease (BD). MATERIAL AND METHODS: One hundred and forty-three (143) patients with BD and 112 healthy controls (HC) were enrolled. Participants were subdivided according to the body mass index (BMI) as lean (<18...
June 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28638682/oral-ulcer-activity-in-behcet-s-disease-poor-medication-adherence-is-an-underestimated-risk-factor
#6
Gonca Mumcu, Fatma Alibaz-Öner, Sibel Yılmaz Öner, Gülsen Özen, Pamir Atagündüz, Nevsun İnanç, Leyla Köksal, Tülin Ergun, Haner Direskeneli
OBJECTIVE: The aim of this study was to evaluate the relationship between oral ulcer activity and medication adherence according to gender in Behçet's disease (BD) patients. MATERIAL AND METHODS: The study group included 330 BD patients (F/M: 167/163, mean age: 38.5±10.5 years). Oral ulcer activity and medication adherence were evaluated in the previous month. Medication adherence was evaluated using the 8-item Morisky Medication Adherence Scale (MMAS-8) having a score range of "0" to "8" with high scores indicating better adherence...
June 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28634508/reversible-rhombencephalitis-in-neuro-beh%C3%A3-et-s-disease
#7
Peter Kang, Robert Bucelli
No abstract text is available yet for this article.
July 2017: Neurohospitalist
https://www.readbyqxmd.com/read/28631704/-beh%C3%A3-et-s-disease-intracardiac-thrombosis-a-description-of-two-cases-and-a-review-of-literature
#8
Z S Alekberova, P S Ovcharov, T A Lisitsyna, A V Volkov, T V Popkova
Behçet's disease (BD) is systemic vasculitis of unknown etiology, which is more common in the countries located along the Great Silk Road. The disease is diagnosed if a patient has 4 key diagnostic signs: aphthous stomatitis, genital sores, and eye and skin lesions. Vascular diseases referred to as minor criteria for BD are characterized by the formation of aneurysms and thrombosis, predominantly in the venous bed. In venous disorders, a blood clot can form in any vessel, including caval, cerebral, pulmonary, and other veins...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28630777/magnetic-resonance-enterography-findings-of-intestinal-beh%C3%A3-et-disease-in-a-child
#9
Tommaso D'Angelo, Romina Gallizzi, Claudio Romano, Giuseppe Cicero, Silvio Mazziotti
Behçet's disease (BD) is a multisystem disorder of unknown aetiology, characterized by recurrent oral ulcers, genital ulcers, uveitis, skin lesions, and pathergy. Gastrointestinal disease outside the oral cavity is well recognized and usually takes the form of small intestinal ulcers, with the most significant lesions frequently occurring in the ileocaecal region. Symptoms usually include nausea, vomiting, colicky abdominal pain, and change in bowel habit and it is not unusual that patients may present late, with life-threatening complications requiring surgery...
2017: Case Reports in Radiology
https://www.readbyqxmd.com/read/28627044/adherence-to-treatment-in-patients-with-behcet-s-disease
#10
Alireza Khabbazi, Farid Karkon Shayan, Morteza Ghojazadeh, Hadise Kavandi, Mehrzad Hajialiloo, Kamal Esalat Manesh, Sousan Kolahi
AIM: Behcet's disease (BD) is a chronic, inflammatory disease with multisystem involvement. Adherence to treatment is low in chronic diseases as well as inflammatory and autoimmune diseases. This study assessed factors associated with non-adherence to treatment in patients with BD. METHODS: All the patients with BD who visited in the outpatient clinic of Connective Tissue Diseases Research Center in Tabriz University of Medical Sciences were included in the study...
June 19, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28620840/quality-of-life-impairment-in-beh%C3%A3-et-s-disease-and-relationship-with-disease-activity-a-prospective-study
#11
Claudia Fabiani, Antonio Vitale, Ida Orlando, Jurgen Sota, Marco Capozzoli, Rossella Franceschini, Mauro Galeazzi, Gian Marco Tosi, Bruno Frediani, Luca Cantarini
Our aim was to prospectively investigate the impact of Behçet's disease (BD), disease activity, and clinical and demographic characteristics on different aspects of quality of life (QoL) measured by the short-form (SF)-36 QoL scale. We administered the SF-36 to 37 consecutive BD patients in different moments of disease activity, and to 23 healthy controls (HC). The eight subcategories of the SF-36 underwent statistical analysis for identifying differences and correlations. Compared to HC, BD patients showed significantly lower mean scores in all SF-36 QoL subscales except mental health and role-emotional...
June 15, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28612244/cerebral-venous-sinus-thrombosis-in-beh%C3%A3-et-s-disease-a-retrospective-case-control-study
#12
Jing Shi, Xinxiang Huang, Guohua Li, Li Wang, Jinjing Liu, Yan Xu, Xiaofeng Zeng, Wenjie Zheng
The objective of the study is to investigate the clinical features of Behçet's disease (BD) complicated with cerebral venous sinus thrombosis (CVST). We retrospectively analyzed the clinical features of age- and gender-matched BD patients with and without CVST. Of the 840 BD patients enrolled, 21 (2.5%, 11 female, mean age 30.3 ± 9.5) were diagnosed as CVST. Eighteen patients (85.7%) developed neurologic manifestations after BD onset, with an average interval of 47.6 months (SD 36.1). Onset of neurologic symptoms was mostly progressive (89...
June 14, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28611570/development-and-improvement-of-simple-colonic-mucosal-ulcer-during-treatment-of-severe-ulcerative-colitis-with-tacrolimus
#13
Ayumi Ito, Bunei Iizuka, Teppei Omori, Shinichi Nakamura, Katsutoshi Tokushige
Diarrhea, melena, and lower abdominal pain developed in a male in his 20s and colonoscopy showed pancolitis-type severe ulcerative colitis (UC). Treatment was initiated with 4,000 mg of 5-aminosalicylic acid and 60 mg/day of prednisolone, but the symptoms and inflammatory reaction worsened with prednisolone dose reduction. Tacrolimus was added to the treatment, which subsequently induced remission. Serial colonoscopies during the treatment showed improvement in ulcer and mucosal edema throughout the entire large intestine, but a new solitary round ulcer appeared at the end of the ileum...
January 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28607794/a-rare-case-of-vasculitis-patched-necrosis-of-cecum-due-to-beh%C3%A3-et-s-disease
#14
Ehsan Shahverdi, Mehdi Morshedi, Faraneh Oraei-Abbasian, Maryam Allahverdi Khani, Roya Khodayarnejad
Isolated cecal necrosis is a rare form of acute ischemic colitis and a rare cause of surgical abdomen. Behçet's disease is a multisystemic autoimmune condition which can induce vasculitis. This can result in cecal necrosis while disease involves colon vessels. We describe a patient with complicated Behçet's disease and ischemic colitis admitted to our hospital. Patient was a 62-year-old female with more accompanying diseases. Histopathologic findings confirmed the diagnosis of ischemic colitis and regarding patient's vision problem and skin lesions, rheumatologic tests were performed which were positive for HLAB5 and HLAB51 suggestive of Behçet's disease; the patient was improved with surgery...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28598773/beh%C3%A3-et-s-syndrome-and-health-related-quality-of-life-influence-of-symptoms-lifestyle-and-employment-status
#15
Amal A Senusi, Dennis Ola, Jan Mather, John Mather, Farida Fortune
OBJECTIVES: Behçet's syndrome (BS) is a chronic multisystemic disorder. The complex pattern of BS symptoms can effect negatively on patients' quality of life. The aim of this study is to evaluate the influence of BS symptoms, oral health related lifestyles and employment status on Health Related Quality of Life (HRQoL). METHODS: A questionnaire was mailed to a cohort of 641 adult members of the Behçet's Syndrome Society (BSS) and patients attending a Behçet's syndrome centre in the UK...
June 8, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28598323/associations-of-hla-b-alleles-with-beh%C3%A3-et-s-disease-in-ireland
#16
Fahd Adeeb, Adaeze Ugwoke, Austin G Stack, Alexander D Fraser
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May 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28598056/neuro-behcet-s-disease-presenting-as-a-young-stroke
#17
Nishit Biniwale, Rutuja Kibe, Avanti Biniwale
Neuro-Behcet's disease (NBD) is a rare neurological manifestation of the systemic small vessel vasculitis called Behcet's disease. It can present in various ways with predilection for the brain stem, thalamo- hypothalamic regions, cerebellum and basal ganglia. In this case, we describe a case of young stroke that was later attributed to NBD.
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28596917/assessment-of-vascular-change-using-swept-source-optical-coherence-tomography-angiography-a-new-theory-explains-central-visual-loss-in-behcet-s-disease
#18
Thanapong Somkijrungroj, Sritatath Vongkulsiri, Wijak Kongwattananon, Peranut Chotcomwongse, Sasivarin Luangpitakchumpol, Korrawan Jaisuekul
OBJECTIVE: To evaluate retinal vascular structural change in ocular Behcet's using optical coherence tomography angiography (OCTA) and fluorescein angiography (FA). METHODS: An analytic cross-sectional study of 37 eyes of 21 Behcet's uveitic patients was performed. Foveal retinal thickness (FRT), perifoveal hypoperfusion areas in superficial capillary plexus (SCP), and deep capillary plexus (DCP) were measured with swept-source optical coherence tomography and OCTA...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28596287/incidence-and-prevalence-of-uveitis-in-south-korea-a-nationwide-cohort-study
#19
Tyler Hyungtaek Rim, Sung Soo Kim, Don-Il Ham, Seung-Young Yu, Eun Jee Chung, Sung Chul Lee
AIM: To evaluate the incidence and prevalence of uveitis and associated risk factors in South Korea. METHODS: For this retrospective national cohort study, approximately 1 000 000 Korean residents were randomly selected from the Korean National Health Insurance Service database. Uveitis was defined according to the Korean Classification of Diseases. The uveitis incidence and prevalence were calculated. Sociodemographic factors and comorbidities associated with uveitis were evaluated via Cox proportional regression models...
June 8, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28592884/enhancement-of-th1-th17-inflammation-by-trim21-in-beh%C3%A3-et-s-disease
#20
Yuri Ahn, Ji-Hye Hwang, Zhenlong Zheng, Dongsik Bang, Do-Young Kim
The etiology of Behçet's disease (BD), a chronic, multisystemic autoinflammatory and autoimmune disease, remains unknown; however, researchers have postulated that infectious agents, such as herpes simplex virus, are significant triggering factors of BD. Tripartite motif-containing (TRIM) proteins exhibit antiviral properties, mediating antiviral defense mechanisms. The purpose of this study was to investigate TRIM21 protein expression in the monocytes of BD patients and to identify the role of TRIM21 in immune dysregulation in BD...
June 7, 2017: Scientific Reports
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