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https://www.readbyqxmd.com/read/29150407/disease-trends-over-time-and-cd4-ccr5-t-cells-expansion-predict-carotid-atherosclerosis-development-in-patients-with-systemic-lupus-erythematosus
#1
A Baragetti, G A Ramirez, M Magnoni, K Garlaschelli, L Grigore, M Berteotti, I Scotti, E Bozzolo, A Berti, P G Camici, A L Catapano, A A Manfredi, E Ammirati, G D Norata
BACKGROUND AND AIM: Patients with Systemic Lupus Erythematosus (SLE) present increased cardiovascular mortality compared to the general population. Few studies have assessed the long-term development and progression of carotid atherosclerotic plaque in SLE patients. Our aim was to investigate the association of clinical and laboratory markers of disease activity and classical cardiovascular risk factors (CVRF) with carotid atherosclerosis development in SLE patients in a prospective 5-year study...
September 18, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29145340/open-repair-of-intraoperative-popliteal-artery-injury-during-total-knee-arthroplasty-in-a-patient-with-severe-hemophilia-a-a-case-report-and-literature-review
#2
Bin Feng, Ke Xiao, Jiang Shao, Yu Fan, Xisheng Weng
RATIONALE: Arterial injuries during total knee arthroplasty (TKA) though rare may occur. Hemophilia may further challenge the management of such injury. PATIENT CONCERNS: A 48-year-old male patient with severe hemophilia type A and stiff knee arthropathy underwent bilateral TKAs. Left popliteal artery injury was detected at the end of the left TKA. DIAGNOSES: Urgent angiography confirmed the diagnosis of the left popliteal artery transection...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29142450/autologous-intrauterine-platelet-rich-plasma-instillation-for-suboptimal-endometrium-in-frozen-embryo-transfer-cycles-a-pilot-study
#3
Sunita R Tandulwadkar, Manasi V Naralkar, Akash D Surana, M Selvakarthick, Avinash H Kharat
Introduction: This pilot study was to evaluate the effectiveness of intrauterine infusion of autologous platelet-rich plasma (PRP) in infertile women undergoing frozen embryo transfer cycles with suboptimal endometrium. Material and Methods: Intrauterine instillation of autologous PRP was done in 68 women between 22 and 40 years, over 8 months, with suboptimal endometrial growth, and patients with repeated cycle cancellations, in addition to Estradiol valerate. Frozen embryo transfer was performed when the endometrium reached an optimal pattern in terms of thickness, appearance, and vascularity...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142342/prevalence-of-subclinical-peripheral-vascular-disease-in-obese-egyptian-patients
#4
Jehan Ahmed Younes, Nahla Dessoki El-Sayed, Ayman Ismail Kamel
Objective: To detect subclinical peripheral vascular disease in obese Egyptian patients and establish relations between obesity, metabolic risk factors, and PVD. Methods: This was a prospective case-control study including 100 obese patients (BMI >30) (G1). In addition, 100 age and sex matched non-obese healthy subjects as a control group (G2). Both groups were subjected to duplex ultrasound, Radionuclide muscle scan. Angiography was done for 17 patients. Results: The image pattern of 99mTc-MIBI muscles uptake was studied and perfusion reserve (PR%) was calculated in (G1) and (G2)...
October 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29140571/is-overactive-bladder-microvasculature-disease-a-component-of-systemic-atheroscleorosis
#5
Ahmet Ozgur Yeniel, Ahmet Mete Ergenoglu, Reci Meseri, Erkan Kismali, Anıl Ari, Gulgun Kavukcu, Hikmet H Aydin, Handan Ak, Sevcan Atay, Ismail Mete Itil
AIMS: To evaluate the relationship between overactive bladder (OAB) and systemic atherosclerosis in a cohort of women. METHODS: In this case-control study, we assessed atherosclerosis indicators, such as Framingham risk scores and carotid and femoral artery intima-media thickness, and evaluated possible bladder wall responses to atherosclerosis using endovaginal color Doppler ultrasound and the detection of urinary cytokines in women with OAB and in controls. Quantitative assessment of blood perfusion at the bladder neck was performed using a method that allows for the dynamic monitoring of flow in a predefined region of interest at every point of the cardiac cycle...
November 15, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29136193/early-first-trimester-uteroplacental-flow-and-the-progressive-disintegration-of-spiral-artery-plugs-new-insights-from-contrast-enhanced-ultrasound-and-tissue-histopathology
#6
V H J Roberts, T K Morgan, P Bednarek, M Morita, G J Burton, J O Lo, A E Frias
STUDY QUESTION: Does the use of a vascular contrast agent facilitate earlier detection of maternal flow to the placental intervillous space (IVS) in the first trimester of pregnancy? SUMMARY ANSWER: Microvascular filling of the IVS was demonstrated by contrast-enhanced ultrasound from 6 weeks of gestation onwards, earlier than previously believed. WHAT IS KNOWN ALREADY: During placental establishment and remodeling of maternal spiral arteries, endovascular trophoblast cells invade and accumulate in the lumen of these vessels to form 'trophoblast plugs'...
November 10, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29132038/hemodynamics-of-the-corpus-luteum-in-mares-during-experimentally-impaired-luteogenesis-and-partial-luteolysis
#7
J C Ferreira, L F Novaes Filho, Y L Boakari, H S Canesin, D L Thompson, F S Lima, C Meira
The aim of the current project was to characterize the luteal vascularity and the plasma concentrations of progesterone (P4), prolactin (PRL) and 13,14-dihydro-15-keto-PGF2α (PGFM) in mares with luteal disturbances during early and mid-diestrus. In Experiment 1, twenty-one mares were treated with 2 mL of 0.9% NaCl, or 1 mg Dinoprost, or 10 mg Dinoprost on day two after ovulation (Control-D2, 1/10PGF-D2 and PGF-D2 groups, respectively; n = 7 mares/group). In Experiment 2, similar treatments were performed eight days post-ovulation using a different cohort of 21 mares (Control-D8, 1/10PGF-D8 and PGF-D8 groups, respectively; n = 7 mares/group)...
November 4, 2017: Theriogenology
https://www.readbyqxmd.com/read/29131095/intracranial-internal-carotid-artery-wall-calcification-in-ischemic-strokes-treated-with-thrombolysis
#8
Miguel Tábuas-Pereira, João Sargento-Freitas, Fernando Silva, Joana Parra, Patrícia Mendes, Vera Seara, Miguel Mesquita, Mariana Baptista, Gustavo Cordeiro, Luis Cunha
BACKGROUND: Calcifications are an important element of atherosclerotic plaques and have been used as a marker of atherosclerosis and clinical outcome predictor in different vascular territories. CT-scan, performed in the acute ischemic stroke setting, can reliably detect intracranial arterial calcifications. OBJECTIVES: To investigate the association between intracranial internal carotid artery calcification and functional outcome, symptomatic intracerebral hemorrhage (sICH), recanalization, and death...
November 13, 2017: European Neurology
https://www.readbyqxmd.com/read/29129735/arterial-stiffness-and-cerebral-hemodynamic-pulsatility-during-cognitive-engagement-in-younger-and-older-adults
#9
Kevin S Heffernan, Jacqueline A Augustine, Wesley K Lefferts, Nicole L Spartano, William E Hughes, Randall S Jorgensen, Brooks B Gump
This study examined central artery stiffness and hemodynamic pulsatility during cognitive engagement in younger and older adults. METHODS: Vascular-hemodynamic measures were completed in 19 younger (age 35±1yrs) and 20 older (age 69±2yrs) adults at rest and during a Stroop task. Aortic stiffness (carotid-femoral pulse wave velocity, PWV) and carotid pulse pressure (PP) were assessed using applanation tonometry. Carotid stiffness was assessed as a single-point PWV using Doppler Ultrasound...
November 9, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/29127268/sickle-mice-are-sensitive-to-hypoxia-ischemia-induced-stroke-but-respond-to-tissue-type-plasminogen-activator-treatment
#10
Yu-Yo Sun, Jolly Lee, Henry Huang, Mary B Wagner, Clinton H Joiner, David R Archer, Chia-Yi Kuan
BACKGROUND AND PURPOSE: The effects of lytic stroke therapy in patients with sickle cell anemia are unknown, although a recent study suggested that coexistent sickle cell anemia does not increase the risk of cerebral hemorrhage. This finding calls for systemic analysis of the effects of thrombolytic stroke therapy, first in humanized sickle mice, and then in patients. There is also a need for additional predictive markers of sickle cell anemia-associated vasculopathy. METHODS: We used Doppler ultrasound to examine the carotid artery of Townes sickle mice tested their responses to repetitive mild hypoxia-ischemia- and transient hypoxia-ischemia-induced stroke at 3 or 6 months of age, respectively...
November 10, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29124818/diagnosis-and-management-of-patients-with-enhanced-myometrial-vascularity-associated-with-retained-products-of-conception
#11
Yvette S Groszmann, Amie Lynn Healy Murphy, Beryl R Benacerraf
OBJECTIVES: We performed this study to assess the complication rate, including the estimated amount of blood loss, in patients who underwent dilation and curettage for treatment of retained products of conception with markedly enhanced myometrial vascularity mimicking arteriovenous malformations. METHODS: This is a retrospective medical records review study of patients with retained products of conception with enhanced myometrial vascularity presenting to our ultrasound unit between August 1, 2015 and August 1, 2017...
November 10, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29123079/a-case-of-round-ligament-varices-presenting-in-pregnancy
#12
Luis F García-Paredes, Stephanie C Torres-Ayala, Wilmarie Rivera-Hernández, Wilma Rodriguez Mojica
BACKGROUND Round ligament varices (RLV) are rare and are almost exclusively seen in pregnant women. RLV may clinically resemble an inguinal hernia, inguinal mass, or other pathology involving the inguinal canal and round ligament. Ultrasound imaging is important to make the diagnosis of RLV. CASE REPORT A 34-year-old Hispanic woman, gravida 1 para 0, at 34 weeks gestation, presented to our outpatient department with a complaint of a small, painless, reducible right inguinal mass. Gray-scale sonography showed an asymmetric right inguinal anechoic mass composed of multiple serpentine tubular channels, which became more prominent when the patient performed a Valsalva maneuver...
November 10, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29122964/enhanced-muscle-blood-flow-with-intermittent-pneumatic-compression-of-the-lower-leg-during-plantar-flexion-exercise-and-recovery
#13
Kathryn A Zuj, Chekema N Prince, Richard L Hughson, Sean D Peterson
This study tested the hypothesis that intermittent compression of the lower limb would increase blood flow during exercise and post-exercise recovery. Data were collected from 12 healthy individuals (8 men) who performed three minutes of standing plantar flexion exercise. Three conditions were tested: no applied compression (NoComp), compression during the exercise period only (ExComp), and compression during two minutes of standing post-exercise recovery (RecComp). Doppler ultrasound was used to determine superficial femoral artery (SFA) blood flow responses...
November 9, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29122223/the-utility-of-ultrasound-superb-microvascular-imaging-for-evaluation-of-breast-tumour-vascularity-comparison-with-colour-and-power-doppler-imaging-regarding-diagnostic-performance
#14
A Y Park, B K Seo, O H Woo, K S Jung, K R Cho, E K Park, S H Cha, J Cha
AIM: To investigate the utility of superb microvascular imaging (SMI) for evaluating the vascularity of breast masses in comparison with colour or power Doppler ultrasound (US) and the effect on diagnostic performance. MATERIALS AND METHODS: A total of 191 biopsy-proven masses (99 benign and 92 malignant) in 166 women with greyscale, colour Doppler, power Doppler, and SMI images were enrolled in this retrospective study. Three radiologists analysed the vascular images using a three-factor scoring system to evaluate the number, morphology, and distribution of tumour vessels...
November 6, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29120064/size-and-ultrasound-features-affecting-results-of-ultrasound-guided-fine-needle-aspiration-of-thyroid-nodules
#15
YiJie Dong, MinJing Mao, WeiWei Zhan, JianQiao Zhou, Wei Zhou, JieJie Yao, YunYun Hu, Yan Wang, TingJun Ye
OBJECTIVES: Our goal was to assess the diagnostic efficacy of ultrasound (US)-guided fine-needle aspiration (FNA) of thyroid nodules according to size and US features. METHODS: A retrospective correlation was made with 1745 whole thyroidectomy and hemithyroidectomy specimens with preoperative US-guided FNA results. All cases were divided into 5 groups according to nodule size (≤5, 5.1-10, 10.1-15, 15.1-20, and >20 mm). For target nodules, static images and cine clips of conventional US and color Doppler were obtained...
November 9, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29119649/prospective-multimodal-imaging-assessment-of-locally-advanced-cervical-cancer-patients-administered-by-chemoradiation-followed-by-radical-surgery-the-price-prospective-imaging-of-cervical-cancer-and-neoadjuvant-treatment-study-2-the-role-of-ultrasound-after
#16
Antonia Carla Testa, Francesca Moro, Tina Pasciuto, Maria Cristina Moruzzi, Alessia Di Legge, Gilda Fuoco, Rosa Autorino, Angela Collarino, Benedetta Gui, Gian Franco Zannoni, Antonietta Gambacorta, Maura Miccò, Vittoria Rufini, Giovanni Scambia, Gabriella Ferrandina
OBJECTIVE: To determine the diagnostic performance of two-dimensional ultrasound parameters, three-dimensional power Doppler and intravenous contrast enhanced indices in detecting residual disease in locally advanced cervical cancer patients triaged to neoadjuvant treatment followed by radical surgery. METHODS: Between October 2010 and June 2014, 108 women with histologically documented cervical cancer and FIGO stage IB2-IVA were screened and 88 of them were included in the final analysis...
November 8, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29119034/a-unique-case-of-testicular-compromise-in-a-patient-with-ovotesticular-disorder-of-sexual-development-and-a-solitary-testicle
#17
Ethan Vargo, Lillianne Stanitsas, Mark Memo
Ovotesticular disorder of sexual development (OT-DSD), previously true hermaphroditism, is a condition in which one or both gonads contain testicular and ovarian tissue. A 23-year-old OT-DSD male patient presented with continuous pain in his right testicle which had been previously intermittent over the past five days. The patient had a prior history of left ovotestis removal with prosthesis placement, a right undescended testicle with aberrant anatomy, and hypospadias repair, all of which were corrected shortly after birth...
2017: Case Reports in Urology
https://www.readbyqxmd.com/read/29117995/the-role-of-mitochondria-derived-reactive-oxygen-species-in-microvascular-dysfunction-in-chronic-kidney-disease
#18
Danielle L Kirkman, Bryce J Muth, Meghan G Ramick, Raymond R Townsend, David G Edwards
Cardiovascular disease is the leading cause of mortality in Chronic Kidney Disease (CKD). Mitochondrial dysfunction secondary to CKD is a potential source of oxidative stress that may impair vascular function. This study sought to determine if mitochondria derived reactive oxygen species contribute to microvascular dysfunction in Stage 3-5 CKD. Cutaneous vasodilation in response to local heating was assessed in 20 CKD patients (60±13 years; eGFR 46±13ml/kg/1.73m2) and eleven matched healthy participants (58±2 years; eGFR>90ml/kg/1...
November 8, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/29112741/atherosclerosis-as-a-potential-pitfall-in-the-diagnosis-of-giant-cell-arteritis
#19
Eugenio De Miguel, Luis M Beltran, Irene Monjo, Francesco Deodati, Wolfgang A Schmidt, Juan Garcia-Puig
Objectives: To explore whether the increase in the intima-media thickness (IMT) in arteriosclerotic disease correlates with the increase in the IMT in temporal arteries (TAs) and if that could mimic the US GCA halo sign. Methods: Consecutive patients ⩾50 years old with high vascular risk and without signs or symptoms of GCA were included. The carotid US IMT measurements were obtained using a standardized software radiofrequency-tracking technology. Colour Doppler US and grey-scale measurements of the IMT in the branches of both TAs were performed by a second sonographer using a 22 MHz probe...
November 2, 2017: Rheumatology
https://www.readbyqxmd.com/read/29111423/maternal-cardiovascular-dysfunction-in-women-with-early-onset-preeclampsia-and-late-onset-preeclampsia-a-cross-sectional-study
#20
Sindhura Vaddamani, Anish Keepanasseril, Ajith Ananthakrishna Pillai, Binay Kumar
OBJECTIVES: To compare the cardiovascular changes associated with early onset (EOPE) and late onset (LOPE) subtypes of preeclampsia. METHODS: A prospective matched cross-sectional study involving 50 women each with early and late onset subtypes of preeclampsia conducted in a tertiary hospital in South India. Cardiac function and remodelling were assessed by conventional 2D, M-mode and doppler echocardiography. RESULTS: Women with EOPE had a significantly more altered left ventricular (LV) geometry, global LV diastolic dysfunction, impairment in myocardial contractility (40% vs...
October 25, 2017: Pregnancy Hypertension
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