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https://www.readbyqxmd.com/read/29328902/hypothermia-and-severe-first-degree-heart-block
#1
Kevin Bryan Uy Lo, Alison Nelson
No abstract text is available yet for this article.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29260074/bilateral-orbital-marginal-zone-b-cell-lymphoma-of-the-mucosa-associated-lymphoid-tissue-in-a-patient-with-hepatitis-b-virus-infection
#2
Pei-Hsuan Lin, Yoshiyuki Kitaguchi, Jacqueline Mupas-Uy, Yasuhiro Takahashi, Hirohiko Kakizaki
Purpose: To report a case of marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the bilateral orbit with chronic hepatitis B virus (HBV) infection. Observations: A 72-year-old man with chronic HBV infection presented with a bilateral proptosis with slight restriction of ocular motility for 9 months. Computed tomographic images showed well-defined, isodense masses in the bilateral superolateral orbit. Magnetic resonance images showed isointense on T1-and hyperintense on T2-weighted images, with bilateral involvements of the lateral rectus muscles reaching the superior orbital fissures...
September 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29241922/single-incision-anterior-apical-mesh-and-sacrospinous-ligament-fixation-in-pelvic-prolapse-surgery-at-36-months-follow-up
#3
Tsia-Shu Lo, Ahlam Mahmoud Al-Kharabsheh, Yiap Loong Tan, Leng Boi Pue, Wu-Chiao Hsieh, Ma Clarissa Uy-Patrimonio
OBJECTIVE: To compare the clinical efficacy, recurrence, complications and quality of life changes 3 years after Elevate-A/single incision mesh surgery anterior apical (SIM A) and sacrospinous ligament fixation (SSF) in the management of pelvic organ prolapse (POP). MATERIALS AND METHODS: A prospective cohort study, 139 women, underwent transvaginal surgery for anterior and/or apical POP > stage 2, 69 patients had SIM A and 70 patients had SSF. The objective cure was defined as POP ≤ stage 1 anterior, apical according to POP-Q...
December 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29213251/who-wants-to-be-an-intrapreneur-relations-between-employees-entrepreneurial-professional-and-leadership-career-motivations-and-intrapreneurial-motivation-in-organizations
#4
Kim-Yin Chan, Moon-Ho R Ho, Jeffrey C Kennedy, Marilyn A Uy, Bianca N Y Kang, Olexander S Chernyshenko, Kang Yang T Yu
This paper reports an empirical study conducted to examine the relationship between employees' Entrepreneurial, Professional, and Leadership (EPL) career motivations and their intrapreneurial motivation. Using data collected from 425 working adults in the research/innovation and healthcare settings, we develop a self-report measure of employee intrapreneurial motivation. We also adapt an existing self-report measure of E, P, and L career motivations (previously developed and used with university students) for use with working adult organizational employees...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29210293/phosphatidylcholine-attenuated-docetaxel-induced-peripheral-neurotoxicity-in-rats
#5
Sung Tae Kim, Eun Jung Kyung, Jung Sook Suh, Ho Sung Lee, Jun Ho Lee, Soo In Chae, Eon Sub Park, Yoon Hee Chung, Jinhyung Bae, Tae Jin Lee, Won Mo Lee, Uy Dong Sohn, Ji Hoon Jeong
Docetaxel is a taxane chemotherapeutic agent used in the treatment of breast cancer, prostate cancer and gastric cancer, but several side effects such as peripheral neurotoxicity could occur. The present study was designed to investigate the therapeutic potential of phosphatidylcholine (PC) on docetaxel-induced peripheral neurotoxicity. Rats were randomly divided into three groups and treated for 4 weeks. Behavioral tests were conducted to measure the effects of PC on docetaxel-induced decreases in mechanical & thermal nociceptive threshold...
December 6, 2017: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29195335/mapping-of-external-cavity-modes-for-a-laser-diode-subject-to-phase-conjugate-feedback
#6
Lionel Weicker, Chi-Hak Uy, Delphine Wolfersberger, Marc Sciamanna
We numerically investigate the dynamics of a semiconductor laser subject to phase-conjugate optical feedback. We explore the effects of the laser model and feedback parameters for the generation of time-periodic oscillations of the output power at harmonics of the external cavity frequency, i.e., dynamical solutions that have been named external cavity modes. We point out that both the experimentally tunable and other parameters have an influence on the frequency of such dynamics. Since the delay has to exist, it is not the relevant parameter as we show that the feedback rate fixes the frequency of the periodic self-pulsations...
November 2017: Chaos
https://www.readbyqxmd.com/read/29161590/skin-and-its-regenerative-powers-an-alliance-between-stem-cells-and-their-niche
#7
REVIEW
Kevin Andrew Uy Gonzales, Elaine Fuchs
Tissues have a natural capacity to replace dying cells and to heal wounds. This ability resides in resident stem cells, which self-renew, preserve, and repair their tissue during homeostasis and following injury. The skin epidermis and its appendages are subjected to daily assaults from the external environment. A high demand is placed on renewal and regeneration of the skin's barrier in order to protect the body from infection and dehydration and to heal wounds. This review focuses on the epithelial stem cells of skin, where they come from, where they reside, and how they function in normal homeostasis and wound repair...
November 20, 2017: Developmental Cell
https://www.readbyqxmd.com/read/29117413/comparison-of-wound-sealability-between-femtosecond-laser-constructed-and-manual-clear-corneal-incisions-in-patients-undergoing-cataract-surgery-a-pilot-study
#8
Harvey Siy Uy, Sunil Shah, Mark Packer
PURPOSE: To compare the sealability of femtosecond laser-constructed and manual clear corneal incisions (CCIs) in patients undergoing cataract surgery. METHODS: This prospective, randomized study included 62 eyes of 62 patients with cataract grade 1 to 2 (LOCS scale). The patients were randomly assigned (1:1) for creation of either manual CCI (with a 2.4-mm keratome) or femtosecond laser-assisted CCI (LENSAR, Inc., Orlando, FL) (31 eyes in each group) before undergoing femtosecond laser-assisted cataract surgery...
November 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29098568/the-signaling-of-protease-activated-receptor-2-activating-peptide-induced-contraction-in-cat-esophageal-smooth-muscle-cells
#9
Hyun Su Ha, Se Eun Lee, Hyun Seok Lee, Gil Hyung Kim, Chan Jong Yoon, Jong Soo Han, Ji-Yun Lee, Uy Dong Sohn
Protease-activated receptors (PARs) are a family of G protein-coupled receptors with a unique activation mechanism involving proteolytic cleavage of the extracellular N-terminal domain of the receptor. PAR2 has a contractile effect on esophageal smooth muscle. We investigate the signaling pathways of the PAR2-activating peptide (PAR2-AP) induced contraction in cat esophageal smooth muscle cells. The length of freshly isolated smooth muscle cells and permeabilized cells from feline esophagus were measured by scanning micrometry, and by confirming molecular basis via western blot analysis...
November 2, 2017: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/29058375/patterns-of-infectious-complications-in-acute-myeloid-leukemia-and-myelodysplastic-syndromes-patients-treated-with-10-day-decitabine-regimen
#10
Alaa M Ali, Daniel Weisel, Feng Gao, Geoffrey L Uy, Amanda F Cashen, Meagan A Jacoby, Lukas D Wartman, Armin Ghobadi, Iskra Pusic, Rizwan Romee, Todd A Fehniger, Keith E Stockerl-Goldstein, Ravi Vij, Stephen T Oh, Camille N Abboud, Mark A Schroeder, Peter Westervelt, John F DiPersio, John S Welch
Decitabine has been explored as a reduced-intensity therapy for older or unfit patients with acute myeloid leukemia (AML). To better understand the risk of infections during decitabine treatment, we retrospectively examined the culture results from each infection-related serious adverse event that occurred among 85 AML and myelodysplastic syndromes (MDS) patients treated in a prospective clinical study using 10-day cycles of decitabine at Washington University School of Medicine. Culture results were available for 163 infection-related complications that occurred in 70 patients: 90 (55...
October 23, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/29052771/standardized-radiographic-interpretation-of-thoracic-tuberculosis-in-children
#11
REVIEW
Nathan David P Concepcion, Bernard F Laya, Savvas Andronikou, Pedro A N Daltro, Marion O Sanchez, Jacqueline Austine U Uy, Timothy Reynold U Lim
There is a lack of standardized approach and terminology to classify the diverse spectrum of manifestations in tuberculosis. It is important to recognize the different clinical and radiographic patterns to guide treatment. As a result of changing epidemiology, there is considerable overlap in the radiologic presentations of primary tuberculosis and post-primary tuberculosis. In this article we promote a standardized approach in clinical and radiographic classification for children suspected of having or diagnosed with childhood tuberculosis...
September 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29046900/us-intergroup-study-of-chemotherapy-plus-dasatinib-and-allogeneic-stem-cell-transplant-in-philadelphia-chromosome-positive-all
#12
Farhad Ravandi, Megan Othus, Susan M O'Brien, Stephen J Forman, Chul S Ha, Jeffrey Y C Wong, Martin S Tallman, Elisabeth Paietta, Janis Racevskis, Geoffrey L Uy, Mary Horowitz, Naoko Takebe, Richard Little, Uma Borate, Partow Kebriaei, Laura Kingsbury, Hagop M Kantarjian, Jerald P Radich, Harry P Erba, Frederick R Appelbaum
This multicenter trial was conducted to determine whether the addition of dasatinib to chemotherapy followed by an allogeneic hematopoietic cell transplant (HCT) in patients with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) was feasible. Patients ≥ 18 and ≤ 60 years of age with newly diagnosed Ph+ ALL received up to 8 cycles of alternating hyperCVAD and high dose cytarabine and methotrexate with dasatinib. Patients with an available matched sibling or unrelated donor underwent an allogeneic HCT in first complete remission (CR1) followed by daily dasatinib starting from day 100...
December 27, 2016: Blood Advances
https://www.readbyqxmd.com/read/29043040/marine-protected-area-restricts-demographic-connectivity-dissimilarity-in-a-marine-environment-can-function-as-a-biological-barrier
#13
Masaaki Sato, Kentaro Honda, Wilfredo H Uy, Darwin I Baslot, Tom G Genovia, Yohei Nakamura, Lawrence Patrick C Bernardo, Hiroyuki Kurokochi, Allyn Duvin S Pantallano, Chunlan Lian, Kazuo Nadaoka, Masahiro Nakaoka
The establishment of marine protected areas (MPAs) can often lead to environmental differences between MPAs and fishing zones. To determine the effects on marine dispersal of environmental dissimilarity between an MPA and fishing zone, we examined the abundance and recruitment patterns of two anemonefishes (Amphiprion frenatus and A. perideraion) that inhabit sea anemones in different management zones (i.e., an MPA and two fishing zones) by performing a field survey and a genetic parentage analysis. We found lower levels of abundance per anemone in the MPA compared to the fishing zones for both species (n = 1,525 anemones, p = ...
October 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29039367/availability-of-computerised-medical-record-system-data-to-compare-models-of-child-health-care-in-primary-care-across-europe
#14
Harshana Liyanage, Uy Hoang, Filipa Ferreira, Denise Alexander, Michael Rigby, Mitch Blair, Simon De Lusignan
Computerised medical record (CMR) system data can be used to compare different models of health care for children. We identified sources of data from the Models of Child Health Appraised (MOCHA) project that compares family doctor led with paediatrician led and mixed models of child care using index conditions. Asthma and immunisation coverage are the first of these. We explored the extent to which an established Patient Registries Initiative (PARENT); MOCHA's own survey (MIROI); the European Centre for Disease Control (ECDC) immunisation information system survey and the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP) registry of data sources provided data to make comparisons of child health care...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29034366/a-phase-2-study-incorporating-sorafenib-into-the-chemotherapy-for-older-adults-with-flt3-mutated-acute-myeloid-leukemia-calgb-11001
#15
Geoffrey L Uy, Sumithra J Mandrekar, Kristina Laumann, Guido Marcucci, Weiqiang Zhao, Mark J Levis, Heidi D Klepin, Maria R Baer, Bayard L Powell, Peter Westervelt, Daniel J DeAngelo, Wendy Stock, Ben Sanford, William G Blum, Clara D Bloomfield, Richard M Stone, Richard A Larson
The Cancer and Leukemia Group B (CALGB), now part of the Alliance for Clinical Trials in Oncology, conducted a multicenter, single-arm, phase 2 study in patients ≥60 years with FMS-like tyrosine kinase 3 (FLT3)-mutated acute myeloid leukemia (AML). In this study, sorafenib was added to daunorubicin and cytarabine-based induction and consolidation chemotherapy and was also continued for 12 months of maintenance therapy. The primary end point of the study was overall survival (OS) at 1 year in the FLT3 internal tandem duplication (FLT3-ITD) cohort...
January 24, 2017: Blood Advances
https://www.readbyqxmd.com/read/28972026/interlower-and-postlower-eyelid-retractor-fat-pads-a-cadaveric-microscopic-study
#16
Jacqueline T Mupas-Uy, Yasuhiro Takahashi, Takashi Nakano, Munekazu Naito, Hiroshi Ikeda, Hidetaka Miyazaki, Hirohiko Kakizaki, Raman Malhotra
BACKGROUND: To report the histological microscopic anatomy of the interlower and postlower eyelid retractor (LER) fat pads. METHODS: In this experimental microscopic study, 31 exenterated orbits from 31 Japanese cadavers (19 right and 12 left; 15 male and 16 female; mean age of death, 81.0±8.8 years; range, 52-97 years) fixed in 10% buffered formalin were used. Masson trichrome was used to stain sagittal full sections of exenterated tissues. Microscopic examination of the lower eyelids was carried out...
September 28, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28971245/sacrospinous-ligament-fixation-for-hysteropexy-does-concomitant-anterior-and-posterior-fixation-improve-surgical-outcome
#17
Tsia-Shu Lo, Ma Clarissa Uy-Patrimonio, Wu-Chiao Hsieh, Ju-Chun Yang, Shih Yin Huang, Sandy Chua
INTRODUCTION AND HYPOTHESIS: Uterine preservation in uterine prolapse is an option for young patients. We hypothesized that sacrospinous hysteropexy (SSH) with anchorage to both the anterior and posterior cervix (SSH-ap) would have a better outcome than SSH with anchorage to the posterior cervix only (SSH-p). METHODS: This was a retrospective study including 75 patients who underwent SSH at Chang Gung Memorial Hospital between March 2008 and August 2013. Five were excluded due to incomplete data...
October 2, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28943016/serum-calcium-and-risk-of-sudden-cardiac-arrest-in-the-general-population
#18
COMPARATIVE STUDY
Hirad Yarmohammadi, Audrey Uy-Evanado, Kyndaron Reinier, Carmen Rusinaru, Harpriya Chugh, Jonathan Jui, Sumeet S Chugh
OBJECTIVE: To evaluate the potential role of low serum Ca levels in the occurrence of sudden cardiac arrest (SCA) in the community. PATIENTS AND METHODS: We compared 267 SCA cases [177 (66%) men] and 445 controls [314 (71%) men] from a large population-based study (catchment population ∼1 million individuals) in the US Northwest from February 1, 2002, through December 31, 2015. Patients were included if their age was 18 years or older with available creatinine clearance (CrCl) and serum electrolyte levels for analyses to enable adjustment for renal function...
October 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28931549/sacral-neuromodulation-blocks-pudendal-inhibition-of-reflex-bladder-activity-in-cats-insight-into-the-efficacy-of-sacral-neuromodulation-in-fowler-s-syndrome
#19
Xing Li, Jamie Uy, Michelle Yu, Shun Li, Katherine Theisen, Jeffrey Browning, Bing Shen, Jicheng Wang, James R Roppolo, William C de Groat, Changfeng Tai
This study tested the hypothesis that sacral neuromodulation, i.e. electrical stimulation of afferent axons in sacral spinal root, can block pudendal afferent inhibition of the micturition reflex. In α-chloralose anesthetized cats, pudendal nerve stimulation (PNS) at 3-5 Hz was used to inhibit bladder reflex activity while the sacral S1 or S2 dorsal root was stimulated at 15-30 Hz to mimic sacral neuromodulation and to block the bladder inhibition induced by PNS. The intensity threshold (T) for PNS or S1/S2 dorsal root stimulation (DRS) to induce muscle twitch of anal sphincter or toe was determined...
September 20, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28920650/junior-investigators-get-engaged-in-the-alliance-for-clinical-trials-in-oncology
#20
Geoffrey L Uy, Matthew H G Katz, Judy C Boughey
The success of the Alliance and the cooperative groups in the National Cancer Institute's National Clinical Trials Network is dependent on the cooperative group's ability to help recruit and train the next generation of clinical researchers.
April 2017: Bulletin of the American College of Surgeons
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