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Hickman catheter in hematology

Simone Cesaro, Mara Cavaliere, Anna Pegoraro, Piergiorgio Gamba, Nicola Zadra, Gloria Tridello
We report our decennial experience with 1161 newly-placed long-term central venous catheters inserted in 919 hematology-oncology patients for a total of 413,901 CVC-days of observation. Most of the CVCs were partially-implanted, open-ended, Broviac-Hickman type of CVC (95 %). One thousand and twenty-four complications were recorded equal to 2.47 per 1000 CVC-days. The frequency of complications per CVC, the rate of episodes per 1000 CVC-days, and removal rate were malfunction/occlusion 42 %, 1.18/1000, and 2...
April 2016: Annals of Hematology
Marek Tomaszewski, Wojciech Kosiak, Ninela Irga, Katarzyna Połczyńska
Central venous access consists in inserting a vascular catheter to the vena cava and placing its tip in the vicinity of the opening to the right atrium. In the patients of the Clinic of Pediatrics, Hematology and Oncology at the Academic Clinical Centre of the Medical University in Gdańsk, such implantation procedures are conducted 40-50 times in a year using Broviac/Hickman catheters that are placed in the subclavian vein. In the Ultrasound and Biopsy Laboratory at the clinic mentioned above, approximately 200-250 examinations have been conducted since 2005 to assess the central venous access...
December 2013: Journal of Ultrasonography
L J Worth, M A Slavin, S Heath, J Szer, A P Grigg
The effectiveness of ethanol locks for prevention of central venous catheter (CVC)-associated bloodstream infection (CLABSI) in adult haematology patients has not been thoroughly evaluated. This study aimed to compare prospectively heparinized saline with 70% ethanol locks using 2 h dwell time in patients with tunnelled CVCs. In saline (N = 43) and ethanol (N = 42) groups, CLABSI rates were 6.0 [95% confidence interval (CI): 3.4-9.8] and 4.1 (95% CI: 1.9-7.7) per 1000 CVC days, respectively (P = 0.42). In the ethanol group, two exit-site infections and one tunnel/pocket infection were observed...
September 2014: Journal of Hospital Infection
Margaret Anne Conway, Claire McCollom, Cynthia Bannon
BACKGROUND: Treatment for many children with blood disorders or cancer includes the use of central venous catheters (CVCs). Few prospective studies have been conducted to address flushing guidelines in pediatric hematology oncology patients. Eighteen pediatric hematology oncology units were surveyed regarding current CVC flushing policies and procedures. Results reported extreme variations in CVC flush procedures, which instigated this systematic review. AIMS: The purpose of this project was to critically review current literature and expert opinion regarding CVC flushing practice in the hopes of reporting standardized recommendations...
July 2014: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
Sachin A Jain, Shilin N Shukla, Shailesh S Talati, Sonia K Parikh, Shivani J Bhatt, Vinayak Maka
BACKGROUND: The use of central venous catheters (CVCs) has greatly improved the quality-of-care in cancer patients, yet these catheters may cause serious infectious and thrombotic complications. The aim of this retrospective study was to study the various types of CVCs and their complications. MATERIALS AND METHODS: We studied retrospectively 213 cases of CVCs in our institute with their indications, type and complications from August 2010 to July 2011. RESULTS: A total of 213 CVCs were inserted in patients with hematological (62%) and solid organ malignancies (38%)...
October 2013: Indian Journal of Medical and Paediatric Oncology
Ming Y Lim, Aref Al-Kali, Aneel A Ashrani, Kebede H Begna, Michelle A Elliott, William J Hogan, C Christopher Hook, Scott H Kaufmann, Louis Letendre, Mark R Litzow, Mrinal S Patnaik, Animesh Pardanani, Ayalew Tefferi, Alexandra P Wolanskyj, Diane E Grill, Rajiv K Pruthi
Central venous access devices (CVADs) are used for intravenous therapy in patients with hematological malignancies. There are limited data comparing catheter outcomes in patients with acute myeloid leukemia (AML) undergoing induction chemotherapy. A retrospective review comparing the incidence of early and late CVAD-associated complications and their effect on CVAD removal was performed in patients with AML undergoing induction chemotherapy between 2007 and 2011. Overall, 64 Hickman(®) catheters and 84 peripherally inserted central catheters (PICCs) were inserted...
June 2013: Leukemia & Lymphoma
Ki-Ho Park, Oh-Hyun Cho, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Mi-Na Kim, Dae-Young Kim, Jung-Hee Lee, Je-Hwan Lee, Kyoo-Hyung Lee, Dae Ho Lee, Cheolwon Suh, Sung-Han Kim
There are limited data on the incidence of subsequent bloodstream infection (BSI) and the effect of systemic antibiotics in patients who had positive catheter-drawn blood cultures (CBC) and negative peripheral blood cultures (PBC). We retrospectively reviewed all paired blood cultures from patients with Hickman catheter in the hematology-oncology ward between January 1997 and December 2008. There were 112 episodes with positive CBC and negative PBC. Nine episodes (8.0%; 95% CI, 3.0-13.1%) led to subsequent BSI within 28 days...
May 2011: Diagnostic Microbiology and Infectious Disease
Eleni Apostolopoulou, Vasilios Raftopoulos, Konstantinos Terzis, Ioannis Elefsiniotis
BACKGROUND: Bloodstream Infections (BSIs) in neutropenic patients often cause considerable morbidity and mortality. Therefore, the surveillance and early identification of patients at high risk for developing BSIs might be useful for the development of preventive measures. The aim of the current study was to assess the predictive power of three scoring systems: Infection Probability Score (IPS), APACHE II and KARNOFSKY score for the onset of Bloodstream Infections in hematology-oncology patients...
2010: BMC Infectious Diseases
Simone Cesaro, Gloria Tridello, Mara Cavaliere, Laura Magagna, Patrizia Gavin, Riccardo Cusinato, Nicola Zadra, Giovanni Franco Zanon, Luigi Zanesco, Modesto Carli
PURPOSE: There are limited prospective data on whether the method of flushing affects the complication rate of tunnelled central venous catheters (CVCs). PATIENTS AND METHODS: During a 25-month period, 203 pediatric patients who had newly placed Broviac-Hickman CVCs were randomly assigned to standard flushing with heparin solution or to experimental flushing with normal saline via a positive-pressure cap. RESULTS: Two hundred twenty-one complications were recorded among 75,249 CVC-days (2...
April 20, 2009: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Lennert Slobbe, Abdelilah El Barzouhi, Eric Boersma, Bart J A Rijnders
Diagnosing catheter-related bloodstream infection (CRBSI) still often involves tip culture. The conventional method is the semiquantitative roll plate method. However, the use of a quantitative sonication technique could have additional value, as it may detect endoluminal microorganisms more easily. Because endoluminal infection tends to occur in long-term central venous catheters, we compared both techniques for patients with long-term tunnelled catheters. For 313 consecutive Hickman catheter tips from 279 hematological patients, colonization detection rates were compared by performing both techniques in a random order, using conventional detection cutoffs...
April 2009: Journal of Clinical Microbiology
Diana Averbuch, Rola Makhoul, Victoria Rotshild, Michael Weintraub, Dan Engelhard
The approach to treating febrile non-neutropenic hematooncologic patients with central venous catheters varies. We recently introduced once-daily administration of cefonicid and gentamicin for such children who were in good clinical condition and without focal signs of infection. Our 2-year experience of 125 episodes in 54 children is hereby reported. Absolute neutrophil counts were 550 to 16,700/mm. Bacteremia occurred in 6.4% episodes: only in patients with Hickman/Broviac catheters and not in those with port-a-caths [8/37 (21...
July 2008: Journal of Pediatric Hematology/oncology
L Chee, M Brown, J Sasadeusz, L MacGregor, A P Grigg
BACKGROUND: Catheter-related blood stream infections (CRBSI) cause significant morbidity and mortality in patients with hematological malignancies. Previous studies have identified a predominance of gram-positive organisms causing CRBSI but they included both neutropenic and non-neutropenic patients with solid organ and hematological malignancies. The aim of our study was to evaluate the incidence and microbiological profile of CRBSIs in a specific cohort of patients with hematological malignancies in their non-neutropenic phase of illness...
April 2008: Journal of Infection
K Ullah, P Ahmed, S Raza, T Satti, Q Nisa, S Mirza, F Akhtar, M K Kamal, F M Akhtar
One hundred and fifty-four patients received allogeneic stem cell transplantations from HLA-matched siblings for various hematological disorders from July 2001 to September 2006. Indications for transplantation included aplastic anemia (n=66), beta-thalassemia major (n=40), CML (n=33), acute leukemia (n=8), and miscellaneous disorders (n=7). One hundred and twenty patients were males and 34 were females. Median patient age was 14 years (range, 1(1/4)-54 years). All patients achieved successful engraftment. Median time to engraftment (ANC>0...
December 2007: Transplantation Proceedings
Marie-Cécile Douard, Eric Desruennes, Irène Kriegel, François Blot
Complications on Hickman central venous catheter and venous access ports Hickman central venous catheter and venous access ports are widely used in patients with hematology or oncology disorders. However, these long-term venous access devices can be the source of several kinds of complications that may compromise the functional and/or vital patient's prognosis. All these complications must be known, diagnosed, treated and prevented. If there is no consensus concerning the prevention of catheter-related thrombosis, various methods are now available to diagnose, treat and prevent device-related bloodstream infections...
June 30, 2006: La Revue du Praticien
Amos Adler, Isaac Yaniv, Ester Solter, Enrique Freud, Zmira Samra, Jerry Stein, Salvador Fisher, Itzhak Levy
The aims of this study were to analyze the factors associated with antibiotic failure leading to tunneled central venous catheter (CVC) removal during catheter-associated bloodstream infections (CABSIs) and with recurrence and reinfection in children with cancer. All cases of CABSI in patients attending the Department of Pediatric Hematology-Oncology between November 2000 and November 2003 were reviewed. A total of 207 episodes of CABSI, including multiple episodes involving the same catheter, were identified in 146 of 410 tunneled CVCs (167 Hickman, 243 implantable ports)...
January 2006: Journal of Pediatric Hematology/oncology
A Adler, I Yaniv, R Steinberg, E Solter, Z Samra, J Stein, I Levy
The aim of this study was to define and compare the infectious and non-infectious complications associated with Hickman catheters and implantable ports in children. The study was conducted over a three-year period in the Department of Haematology-Oncology at the Schneider Children's Medical Center of Israel. All patients who required a central venous catheter (CVC) were included in the study. For each episode of catheter-associated bloodstream infection, demographic, clinical and microbiology data were recorded...
March 2006: Journal of Hospital Infection
Nasia Safdar, Dennis G Maki
BACKGROUND: Peripherally inserted central venous catheters (PICCs) are now widely used for intermediate and long-term access in current-day health care, especially in the inpatient setting, where they are increasingly supplanting conventional central venous catheters (CVCs) placed percutaneously into the internal jugular, subclavian, or femoral veins. Data on the risk of PICC-related bloodstream infection (BSI) with PICCs used in hospitalized patients are limited. STUDY OBJECTIVES: To determine the risk of PICC-related BSI in hospitalized patients...
August 2005: Chest
T Møller, N Borregaard, M Tvede, L Adamsen
A functioning tunnelled central venous catheter (CVC) is a crucial device for patients with haematological malignancies receiving high-dose intravenous chemotherapy. Despite the advantages, CVC infections are a major cause of sepsis and prolonged hospital stay. This study investigated the impact of patient education regarding provision of their own catheter care on the frequency of CVC-related infections (CRIs) and was conducted at a specialized haematological unit at the University Hospital of Copenhagen Rigshospitalet...
December 2005: Journal of Hospital Infection
Agnes Lee
Symptomatic subclavian vein thrombosis is a potential complication in approximately 5-10% patients with indwelling central venous catheters. Having reliable tests that would identify those patients with a high risk of catheter-related thrombosis would be clinically useful by helping to tailor thromboprophylaxis. In this case control study by Jansen et al. (see page 499), patients with a Hickman catheter who were undergoing allogeneic bone marrow transplantation for hematological malignancies were investigated...
April 2005: Haematologica
G Fratino, A C Molinari, S Parodi, S Longo, P Saracco, E Castagnola, R Haupt
BACKGROUND: The use of indwelling central venous catheters (CVCs) has become commonplace in the management of children undergoing anticancer treatment. Several types of CVC are available, while information on complications observed in children is scarce. We describe the experience of two tertiary care centers in Italy that prospectively followed up three types of CVC used at both institutions over a 30-month period. PATIENTS AND METHODS: Between January 2000 and May 2002, double-lumen (DL) or single-lumen (SL) Hickman-Broviac (HB) catheters, and single-lumen pressure-activated safety valve (PASV) catheters were used and prospectively evaluated...
April 2005: Annals of Oncology: Official Journal of the European Society for Medical Oncology
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