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https://www.readbyqxmd.com/read/28231679/-use-the-markov-decision-tree-model-to-optimize-vaccination-strategies-of-hepatitis-e-among-women-aged-15-to-49
#1
Z M Chen, S B Ji, X L Shi, Y Y Zhao, X F Zhang, H Jin
Objective: To evaluate the cost-utility of different hepatitis E vaccination strategies in women aged 15 to 49. Methods: The Markov-decision tree model was constructed to evaluate the cost-utility of three hepatitis E virus vaccination strategies. Parameters of the models were estimated on the basis of published studies and experience of experts. Both methods on sensitivity and threshold analysis were used to evaluate the uncertainties of the model. Results: Compared with non-vaccination group, strategy on post-screening vaccination with rate as 100%, could save 0...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231335/immigrants-in-the-one-percent-the-national-origin-of-top-wealth-owners
#2
Lisa A Keister, Brian Aronson
BACKGROUND: Economic inequality in the United States is extreme, but little is known about the national origin of affluent households. Households in the top one percent by total wealth own vastly disproportionate quantities of household assets and have correspondingly high levels of economic, social, and political influence. The overrepresentation of white natives (i.e., those born in the U.S.) among high-wealth households is well-documented, but changing migration dynamics suggest that a growing portion of top households may be immigrants...
2017: PloS One
https://www.readbyqxmd.com/read/28230630/update-on-the-22q11-2-deletion-syndrome-and-its-relevance-to-schizophrenia
#3
Lily Van, Erik Boot, Anne S Bassett
PURPOSE OF REVIEW: Schizophrenia occurs in ∼25% of individuals with 22q11.2 deletion syndrome (22q11.2DS), the strongest known molecular genetic risk factor for schizophrenia. This review highlights recent literature in 22q11.2DS as it pertains to psychosis and schizophrenia. RECENT FINDINGS: Advances in noninvasive prenatal testing allow for early detection of 22q11.2DS in utero, whereas premature birth has been shown to be a significant risk factor for development of psychotic illness in 22q11...
February 21, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28230254/resistance-to-valproic-acid-as-predictor-of-treatment-resistance-in-genetic-generalized-epilepsies
#4
Joanna Gesche, Marina Khanevski, Carl Solberg, Christoph Patrick Beier
This study aimed at defining clinical predictors of drug resistance in adults with genetic generalized epilepsy (GGE) who were treated with a broad spectrum of antiepileptic drugs. Of a cohort of 137 unselected adult GGE patients with long-term follow up, clinical and demographic data, putative prognostic factors (e.g., psychiatric comorbidities, electroencephalography [EEG]), treatment response, and data indicative of social status were collected. Fifty-eight patients had seizures within the past year. Thirty-three patients met the definition of "drug-resistant epilepsy" according to the International League Against Epilepsy (ILAE) definition...
February 23, 2017: Epilepsia
https://www.readbyqxmd.com/read/28229913/increased-risk-of-developing-schizophrenia-in-animals-exposed-to-cigarette-smoke-during-the-gestational-period
#5
Alexandra I Zugno, Mariana B Oliveira, Gustavo A Mastella, Alexandra S A Heylmann, Lara Canever, Felipe D Pacheco, Louyse S Damazio, Sullivan A Citadin, Luiz Antonio de Lucca, Lutiana Roque Simões, Fernanda Malgarin, Josiane Budni, Tatiana Barichello, Patricia F Schuck, João Quevedo
Cigarette smoking during the prenatal period has been investigated as a causative factor of obstetric abnormalities, which lead to cognitive and behavioural changes associated with schizophrenia. The aim of this study was to investigate behaviour and AChE activity in brain structures in adult rats exposed to cigarette smoke during the prenatal period. Pregnant rats were divided into non-PCSE (non-prenatal cigarette smoke exposure) and PCSE (prenatal cigarette smoke exposure) groups. On post-natal day 60, the rats received saline or ketamine for 7days and were subjected to behavioural tasks...
February 13, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28229539/appetite-self-regulation-environmental-and-policy-influences-on-eating-behaviors
#6
Marlene B Schwartz, David R Just, Jamie F Chriqui, Alice S Ammerman
OBJECTIVE: Appetite regulation is influenced by the environment, and the environment is shaped by food-related policies. This review summarizes the environment and policy research portion of an NIH Workshop (Bethesda, MD, 2015) titled "Self-Regulation of Appetite-It's Complicated." METHODS: In this paper, we begin by making the case for why policy is an important tool in efforts to improve nutrition, and we introduce an ecological framework that illustrates the multiple layers that influence what people eat...
March 2017: Obesity
https://www.readbyqxmd.com/read/28229477/-why-not-you-discourses-of-widening-access-on-uk-medical-school-websites
#7
Kirsty Alexander, Tania Fahey Palma, Sandra Nicholson, Jennifer Cleland
CONTEXT: In the UK, applications to medicine from those in lower socio-economic groups remain low despite significant investments of time, interest and resources in widening access (WA) to medicine. This suggests that medical schools' core messages about WA may be working to embed or further reinforce marginalisation, rather than to combat this. Our objective was to investigate how the value of WA is communicated by UK medical schools through their websites, and how this may create expectations regarding who is 'suitable' for medicine...
February 22, 2017: Medical Education
https://www.readbyqxmd.com/read/28229306/behavioral-and-social-sciences-at-the-national-institutes-of-health-adoption-of-research-findings-in-health-research-and-practice-as-a-scientific-priority
#8
William T Riley
The National Institutes of Health's Office of Behavioral and Social Sciences Research (OBSSR) recently released its Strategic Plan for 2017 to 2021. This plan highlights three scientific priorities: (1) improve the synergy of basic and applied behavioral and social sciences research, (2) enhance and promote the research infrastructure, methods, and measures needed to support a more cumulative and integrated approach to behavioral and social sciences research, and (3) facilitate the adoption of behavioral and social sciences research findings in health research and in practice...
February 22, 2017: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/28229247/achieving-population-level-change-through-a-system-contextual-approach-to-supporting-competent-parenting
#9
REVIEW
Matthew R Sanders, Kylie Burke, Ronald J Prinz, Alina Morawska
The quality of parenting children receive affects a diverse range of child and youth outcomes. Addressing the quality of parenting on a broad scale is a critical part of producing a more nurturing society. To achieve a meaningful population-level reduction in the prevalence rates of child maltreatment and social and emotional problems that are directly or indirectly influenced by parenting practices requires the adoption of a broad ecological perspective in supporting families to raise children. We make the case for adopting a multilevel, whole of population approach to enhance competent parenting and describe the essential tasks that must be accomplished for the approach to be successful and its effects measurable...
February 22, 2017: Clinical Child and Family Psychology Review
https://www.readbyqxmd.com/read/28228721/patients-with-chronic-spinal-cord-injury-exhibit-reduced-autonomic-modulation-during-an-emotion-recognition-task
#10
Gonzalo Varas-Díaz, Enzo P Brunetti, Gonzalo Rivera-Lillo, Pedro E Maldonado
Spinal cord injury (SCI) is a devastating event for individuals, who frequently develop motor and sensory impairment as well as autonomic dysfunction. Previous studies reported that autonomic activity plays a major role in social cognition and that difficulties in the ability to interpret social information are commonly observed in a variety of mental disorders, which in turn correlate with a poor autonomic nervous system (ANS) regulation. It is well established that subjects with SCI have an alteration in ANS regulation mechanisms...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28228573/grace-under-pressure-a-drama-based-approach-to-tackling-mistreatment-of-medical-students
#11
Karen M Scott, Špela Berlec, Louise Nash, Claire Hooker, Paul Dwyer, Paul Macneill, Jo River, Kimberley Ivory
A positive and respectful learning environment is fundamental to the development of professional identities in healthcare. Yet medical students report poor behaviour from healthcare professionals that contradict professionalism teaching. An interdisciplinary group designed and implemented a drama-based workshop series, based on applied theatre techniques, to help students develop positive professional qualities and interpersonal skills to deal with challenges in the healthcare setting. We piloted the workshops at the University of Sydney in 2015...
March 2017: Medical Humanities
https://www.readbyqxmd.com/read/28228514/differentiating-causality-and-correlation-in-allometric-scaling-ant-colony-size-drives-metabolic-hypometry
#12
James S Waters, Alison Ochs, Jennifer H Fewell, Jon F Harrison
Metabolic rates of individual animals and social insect colonies generally scale hypometrically, with mass-specific metabolic rates decreasing with increasing size. Although this allometry has wide ranging effects on social behaviour, ecology and evolution, its causes remain controversial. Because it is difficult to experimentally manipulate body size of organisms, most studies of metabolic scaling depend on correlative data, limiting their ability to determine causation. To overcome this limitation, we experimentally reduced the size of harvester ant colonies (Pogonomyrmex californicus) and quantified the consequent increase in mass-specific metabolic rates...
February 22, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28228196/the-hidden-story-of-innovation-charity-hospital-angola-prison-and-the-challenging-of-surgical-dogma
#13
Patrick Greiffenstein, Paul R Hastings
The late 1960s was a period of significant upheaval of social, cultural, and scientific norms. The generally accepted notion of mandatory laparotomy for all penetrating abdominal injuries was among those norms being called into question across the country and many advocated expectant management of selected patients presenting with this type of injury. Leaders of the surgical community published opinions on either side of the argument. The house staff at Charity Hospital during this period was among the busiest in the nation in treating these injuries, many of them inmates of the Louisiana State Penitentiary who used self-inflicted stab wounds to the abdomen as a means of temporary respite from the inhumane conditions in the prison...
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28228151/unravelling-effectiveness-of-a-nurse-led-behaviour-change-intervention-to-enhance-physical-activity-in-patients-at-risk-for-cardiovascular-disease-in-primary-care-study-protocol-for-a-cluster-randomised-controlled-trial
#14
Heleen Westland, Irene D Bos-Touwen, Jaap C A Trappenburg, Carin D Schröder, Niek J de Wit, Marieke J Schuurmans
BACKGROUND: Self-management interventions are considered effective in patients with chronic disease, but trials have shown inconsistent results, and it is unknown which patients benefit most. Adequate self-management requires behaviour change in both patients and health care providers. Therefore, the Activate intervention was developed with a focus on behaviour change in both patients and nurses. The intervention aims for change in a single self-management behaviour, namely physical activity, in primary care patients at risk for cardiovascular disease...
February 22, 2017: Trials
https://www.readbyqxmd.com/read/28228046/into-africa-a-transnational-history-of-catholic-medical-missions-and-social-change
#15
Julia R Cummiskey
No abstract text is available yet for this article.
April 2017: Global Public Health
https://www.readbyqxmd.com/read/28227979/dispersion-entropy-for-the-analysis-of-resting-state-meg-regularity-in-alzheimer-s-disease
#16
Hamed Azami, Mostafa Rostaghi, Alberto Fernandez, Javier Escudero, Hamed Azami, Mostafa Rostaghi, Alberto Fernandez, Javier Escudero, Alberto Fernandez, Javier Escudero, Mostafa Rostaghi, Hamed Azami
Alzheimer's disease (AD) is a progressive degenerative brain disorder affecting memory, thinking, behaviour and emotion. It is the most common form of dementia and a big social problem in western societies. The analysis of brain activity may help to diagnose this disease. Changes in entropy methods have been reported useful in research studies to characterize AD. We have recently proposed dispersion entropy (DisEn) as a very fast and powerful tool to quantify the irregularity of time series. The aim of this paper is to evaluate the ability of DisEn, in comparison with fuzzy entropy (FuzEn), sample entropy (SampEn), and permutation entropy (PerEn), to discriminate 36 AD patients from 26 elderly control subjects using resting-state magnetoencephalogram (MEG) signals...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227241/changes-in-st-qt-and-rr-ecg-intervals-during-acute-stress-in-firefighters-a-pilot-study
#17
Joana S Paiva, Susana Rodrigues, Joao Paulo Silva Cunha, Joana S Paiva, Susana Rodrigues, Joao Paulo Silva Cunha, Susana Rodrigues, Joana S Paiva
Firefighting is a stressful occupation. The monitoring of psychophysiological measures in those professionals can be a way to prevent and early detect cardiac diseases and other stress-related problems. The current study aimed to assess morphological changes in the ECG signal induced by acute stress. A laboratory protocol was conducted among 6 firefighters, including a laboratory stress-inducer task - the Trier Social Stress Task (TSST) - and a 2-choice reaction time task (CRTT) that was performed before (CRTT1) and after (CRTT2) the stress condition...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226665/changes-in-the-eeg-amplitude-as-a-biomarker-for-early-detection-of-alzheimer-s-disease
#18
Ali H Al-Nuaimi, Emmanuel Jammeh, Lingfen Sun, Emmanuel Ifeachor, Ali H Al-Nuaimi, Emmanuel Jammeh, Lingfen Sun, Emmanuel Ifeachor, Emmanuel Jammeh, Lingfen Sun, Ali H Al-Nuaimi, Emmanuel Ifeachor
The rapid increase in the number of older people with Alzheimer's disease (AD) and other forms of dementia represents one of the major challenges to the health and social care systems. Early detection of AD makes it possible for patients to access appropriate services and to benefit from new treatments and therapies, as and when they become available. The onset of AD starts many years before the clinical symptoms become clear. A biomarker that can measure the brain changes in this period would be useful for early diagnosis of AD...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226069/rural-families-interpretations-of-experiencing-unexpected-transition-in-the-wake-of-a-natural-disaster
#19
Gisele Cristina Manfrini Fernandes, Astrid Eggert Boehs, Sharon A Denham, Rosane Gonçalves Nitschke, Jussara Gue Martini
Natural disasters affect populations in various parts of the world. The impacts of disasters can cause many problems to the health of people and disruption to family life, potentially leading to an unexpected transition. The objective of this paper is to present the unexpected transitional experiences of rural families following a natural disaster. A multiple case study of six families was conducted with children and adolescents in a rural area affected by a 2008 disaster in southern Brazil. For data collection, we used participant observation, narrative interviews, genograms, ecomaps and an instrument called calendar routine...
February 13, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28225843/-poverty-and-mental-disability-in-the-criminal-law-the-invisibles
#20
Ezequiel N Mercurio
In recent decades neuroscience research show the negative consequences of poverty in cognitive development. Environmental factors, such as material deprivation, exposure to stressful situations, violence, nutritional deprivation, environmental toxins may shape the developing brain. The changes of the structure and function of the brain since prenatal stages and their consequences can remain stable throughout the life cycle except early interventions are made. Research investigating have found significant link between child poverty and function and structural brain focusing on prefrontal cortex (i...
May 2016: Vertex: Revista Argentina de Psiquiatriá
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