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https://www.readbyqxmd.com/read/28346346/an-effective-terrain-aided-navigation-for-low-cost-autonomous-underwater-vehicles
#1
Ling Zhou, Xianghong Cheng, Yixian Zhu, Chenxi Dai, Jinbo Fu
Terrain-aided navigation is a potentially powerful solution for obtaining submerged position fixes for autonomous underwater vehicles. The application of terrain-aided navigation with high-accuracy inertial navigation systems has demonstrated meter-level navigation accuracy in sea trials. However, available sensors may be limited depending on the type of the mission. Such limitations, especially for low-grade navigation sensors, not only degrade the accuracy of traditional navigation systems, but further impact the ability to successfully employ terrain-aided navigation...
March 25, 2017: Sensors
https://www.readbyqxmd.com/read/28346215/enhanced-optoelectronic-quality-of-perovskite-films-with-excess-ch3nh3i-for-high-efficient-solar-cells-in-ambient-air
#2
Yunhai Zhang, Huiru Lv, Can Cui, Lingbo Xu, Peng Wang, Hao Wang, Xuegong Yu, Jiangsheng Xie, Jiabin Huang, Zeguo Tang, Deren Yang
The solution-processed polycrystalline perovskite film contributes critically to the high photovoltaic performance of perovskite based solar cells (PSCs). The inevitable electronic trap states at grain boundaries and the intrinsic defects such as metallic lead (Pb0) and halide vacancies in perovskite film cause serious carrier recombination loss. Furthermore, the film can easily decompose into PbI2 in moisture atmosphere. Here, we introduce a simple strategy through a small increase in methylammonium iodide (CH3NH3I, MAI) molar proportion (5%) for perovskite fabrication in ambient air with a ~50% relative humidity...
March 27, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28344454/the-effect-of-intermittent-head-cooling-on-aerobic-performance-in-the-heat
#3
Peter Walters, Nathaniel Thom, Kai Libby, Shelby Edgren, Amanda Azadian, Daniel Tannous, Elisabeth Sorenson, Brian Hunt
Thermoregulation is critical for athletes, particularly those for those who must perform in the heat. Most strategies aimed at reducing heat stress have cooled participants before or during activity. The objective of this study is to investigate whether seven minutes of head cooling applied between bouts of aerobic exercise in hot (35 ± 1.0 °C) and dry (14.68 ±4.29% rh) environmental conditions could positively effect participants peak power output (PP) on a maximal effort graded exercise test (GXT). Twenty-two recreational active men ages 18 to 23 (19...
March 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28341160/metabolic-network-failures-in-alzheimer-s-disease-a-biochemical-road%C3%A2-map
#4
Jon B Toledo, Matthias Arnold, Gabi Kastenmüller, Rui Chang, Rebecca A Baillie, Xianlin Han, Madhav Thambisetty, Jessica D Tenenbaum, Karsten Suhre, J Will Thompson, Lisa St John-Williams, Siamak MahmoudianDehkordi, Daniel M Rotroff, John R Jack, Alison Motsinger-Reif, Shannon L Risacher, Colette Blach, Joseph E Lucas, Tyler Massaro, Gregory Louie, Hongjie Zhu, Guido Dallmann, Kristaps Klavins, Therese Koal, Sungeun Kim, Kwangsik Nho, Li Shen, Ramon Casanova, Sudhir Varma, Cristina Legido-Quigley, M Arthur Moseley, Kuixi Zhu, Marc Y R Henrion, Sven J van der Lee, Amy C Harms, Ayse Demirkan, Thomas Hankemeier, Cornelia M van Duijn, John Q Trojanowski, Leslie M Shaw, Andrew J Saykin, Michael W Weiner, P Murali Doraiswamy, Rima Kaddurah-Daouk
INTRODUCTION: The Alzheimer's Disease Research Summits of 2012 and 2015 incorporated experts from academia, industry, and nonprofit organizations to develop new research directions to transform our understanding of Alzheimer's disease (AD) and propel the development of critically needed therapies. In response to their recommendations, big data at multiple levels are being generated and integrated to study network failures in disease. We used metabolomics as a global biochemical approach to identify peripheral metabolic changes in AD patients and correlate them to cerebrospinal fluid pathology markers, imaging features, and cognitive performance...
March 21, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28339468/pbmda-a-novel-and-effective-path-based-computational-model-for-mirna-disease-association-prediction
#5
Zhu-Hong You, Zhi-An Huang, Zexuan Zhu, Gui-Ying Yan, Zheng-Wei Li, Zhenkun Wen, Xing Chen
In the recent few years, an increasing number of studies have shown that microRNAs (miRNAs) play critical roles in many fundamental and important biological processes. As one of pathogenetic factors, the molecular mechanisms underlying human complex diseases still have not been completely understood from the perspective of miRNA. Predicting potential miRNA-disease associations makes important contributions to understanding the pathogenesis of diseases, developing new drugs, and formulating individualized diagnosis and treatment for diverse human complex diseases...
March 24, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28336957/next-generation-sequencing-enables-the-discovery-of-more-diverse-positive-clones-from-a-phage-displayed-antibody-library
#6
Wonjun Yang, Aerin Yoon, Sanghoon Lee, Soohyun Kim, Jungwon Han, Junho Chung
Phage display technology provides a powerful tool to screen a library for a binding molecule via an enrichment process. It has been adopted as a critical technology in the development of therapeutic antibodies. However, a major drawback of phage display technology is that because the degree of the enrichment cannot be controlled during the bio-panning process, it frequently results in a limited number of clones. In this study, we applied next-generation sequencing (NGS) to screen clones from a library and determine whether a greater number of clones can be identified using NGS than using conventional methods...
March 24, 2017: Experimental & Molecular Medicine
https://www.readbyqxmd.com/read/28334972/enrichment-methods-provide-a-feasible-approach-to-comprehensive-and-adequately-powered-investigations-of-the-brain-methylome
#7
Robin F Chan, Andrey A Shabalin, Lin Y Xie, Daniel E Adkins, Min Zhao, Gustavo Turecki, Shaunna L Clark, Karolina A Aberg, Edwin J C G van den Oord
Methylome-wide association studies are typically performed using microarray technologies that only assay a very small fraction of the CG methylome and entirely miss two forms of methylation that are common in brain and likely of particular relevance for neuroscience and psychiatric disorders. The alternative is to use whole genome bisulfite (WGB) sequencing but this approach is not yet practically feasible with sample sizes required for adequate statistical power. We argue for revisiting methylation enrichment methods that, provided optimal protocols are used, enable comprehensive, adequately powered and cost-effective genome-wide investigations of the brain methylome...
February 25, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28333637/multi-scale-multi-feature-context-modeling-for-scene-recognition-in-the-semantic-manifold
#8
Xinhang Song, Shuqiang Jiang, Luis Herranz
Before the big data era, scene recognition was often approached with two-step inference using localized intermediate representations (objects, topics, etc). One of such approaches is the semantic manifold (SM), in which patches and images are modeled as points in a semantic probability simplex. Patch models are learned resorting to weak supervision via image labels, which leads to the problem of scene categories co-occurring in this semantic space. Fortunately, each category has its own cooccurrence patterns that are consistent across the images in that category...
March 22, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28333497/not-all-nonnormal-distributions-are-created-equal-improved-theoretical-and-measurement-precision
#9
Harry Joo, Herman Aguinis, Kyle J Bradley
We offer a four-category taxonomy of individual output distributions (i.e., distributions of cumulative results): (1) pure power law; (2) lognormal; (3) exponential tail (including exponential and power law with an exponential cutoff); and (4) symmetric or potentially symmetric (including normal, Poisson, and Weibull). The four categories are uniquely associated with mutually exclusive generative mechanisms: self-organized criticality, proportionate differentiation, incremental differentiation, and homogenization...
March 23, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28332113/the-critical-power-concept-applications-to-sports-performance-with-a-focus-on-intermittent-high-intensity-exercise
#10
REVIEW
Andrew M Jones, Anni Vanhatalo
The curvilinear relationship between power output and the time for which it can be sustained is a fundamental and well-known feature of high-intensity exercise performance. This relationship 'levels off' at a 'critical power' (CP) that separates power outputs that can be sustained with stable values of, for example, muscle phosphocreatine, blood lactate, and pulmonary oxygen uptake ([Formula: see text]), from power outputs where these variables change continuously with time until their respective minimum and maximum values are reached and exercise intolerance occurs...
March 22, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28324926/statistical-approach-for-lightweight-detection-of-anomalies-in-ecg
#11
Ihor Vasyltsov, Changgyu Bak, Jiseung Jeong
In this paper the application of statistical approach for anomaly detection in a wearable ECG monitor has been considered. The method is based on the usage of the pre-defined expected behavior of the monitored biomedical signal and its on-line comparison with real-time measurements. Such comparison can be implemented based on the statistical model of ECG signal. To test the accuracy of the proposed method a ProSim 8 simulator was used to generate ECG signals. Our experiments showed that critical anomalies in ECG, such as Cardiac Failure, different types of Arrhythmia, and ST-segment deviations can be detected with high precision (96~100%), while false positive rate over typical NSR signal is low (<;4%)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28323591/treatment-and-monitoring-of-central-serous-chorioretinopathy-in-pilots
#12
Ari Shinojima, Ryusaburo Mori, Kyoko Fujita, Mitsuko Yuzawa
BACKGROUND: Central serous chorioretinopathy (CSC), which has the characteristics of a serous retinal detachment (SRD) in the macular area, affects mostly men in the 30- to 50-yr age range. Some patients have persistent SRD, which may cause retinal thinning and photoreceptor impairment. CSC symptoms are gradual vision loss and/or metamorphopsia. Some commercial airline pilots are concerned about CSC symptoms, which can disqualify them from flying for months and can also reoccur. Thus, careful monitoring and treatment of CSC are critical for pilots, especially those with chronic or recurrent CSC...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28317579/the-influence-of-neural-invasion-on-survival-and-tumor-recurrence-in-pancreatic-ductal-adenocarcinoma-a-systematic-review-and-meta-analysis
#13
REVIEW
Stephan Schorn, Ihsan Ekin Demir, Bernhard Haller, Florian Scheufele, Carmen Mota Reyes, Elke Tieftrunk, Mine Sargut, Ruediger Goess, Helmut Friess, Güralp Onur Ceyhan
OBJECTIVES: To assess the impact of neural invasion/NI on overall survival/OS and tumor recurrence in pancreatic ductal adenocarcinoma/PDAC. SUMMARY BACKGROUND DATA: NI is a histopathological hallmark of PDAC. Although some studies suggested an important role for NI on OS, disease-free/DFS and progression-free survival/PFS in PDAC, there is still no consensus on the actual role of NI on survival and local recurrence in PDAC. METHODS: Pubmed, Cochrane library, Ovid and Google Scholar were screened for the terms "pancreatic ductal adenocarcinoma", "pancreatic cancer", "survival", "tumor recurrence" and "perineural invasion"...
March 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28316563/a-saccade-based-framework-for-real-time-motion-segmentation-using-event-based-vision-sensors
#14
Abhishek Mishra, Rohan Ghosh, Jose C Principe, Nitish V Thakor, Sunil L Kukreja
Motion segmentation is a critical pre-processing step for autonomous robotic systems to facilitate tracking of moving objects in cluttered environments. Event based sensors are low power analog devices that represent a scene by means of asynchronous information updates of only the dynamic details at high temporal resolution and, hence, require significantly less calculations. However, motion segmentation using spatiotemporal data is a challenging task due to data asynchrony. Prior approaches for object tracking using neuromorphic sensors perform well while the sensor is static or a known model of the object to be followed is available...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28306349/utility-of-critical-items-within-the-recognition-memory-test-and-word-choice-test
#15
Laszlo A Erdodi, Bradley T Tyson, Christopher A Abeare, Brandon G Zuccato, Jaspreet K Rai, Kristian R Seke, Sanya Sagar, Robert M Roth
This study was designed to examine the clinical utility of critical items within the Recognition Memory Test (RMT) and the Word Choice Test (WCT). Archival data were collected from a mixed clinical sample of 202 patients clinically referred for neuropsychological testing (54.5% male; mean age = 45.3 years; mean level of education = 13.9 years). The credibility of a given response set was psychometrically defined using three separate composite measures, each of which was based on multiple independent performance validity indicators...
March 17, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28302523/evaluation-of-performance-indicators-applied-to-a-material-recovery-facility-fed-by-mixed-packaging-waste
#16
Maria Laura Mastellone, Raffaele Cremiato, Lucio Zaccariello, Roberta Lotito
Most of the integrated systems for municipal solid waste management aim to increase the recycling of secondary materials by means of physical processes including sorting, shredding and reprocessing. Several restrictions prevent from reaching a very high material recycling efficiency: the variability of the composition of new-marketed materials used for packaging production and its shape and complexity are critical issues. The packaging goods are in fact made of different materials (aluminium, polymers, paper, etc...
March 14, 2017: Waste Management
https://www.readbyqxmd.com/read/28302463/critical-power-testing-or-self-selected-cycling-which-one-is-the-best-predictor-of-maximal-metabolic-steady-state
#17
Felipe Mattioni Maturana, Daniel A Keir, Kaitlin M McLay, Juan M Murias
Critical power (CP) demarcates the boundary between heavy and very heavy exercise intensity domains, and therefore, the power output (PO) that can be sustained at the maximal metabolic steady-state during constant-PO exercise (i.e., maximal lactate steady-state (MLSS)). However, the estimated CP does not always reflect a sustainable intensity of exercise, where blood lactate concentration ([La]) and oxygen uptake (V˙O2) reach a plateau. OBJECTIVES: To test cyclists' ability to predict their highest PO associated with metabolic steady-state based on their own perception of effort...
January 24, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28302426/proximity-of-lateral-critical-structures-to-the-all-epiphyseal-outside-in-femoral-tunnels-in-pediatric-anterior-cruciate-ligament-reconstruction
#18
Mark K Lane, Jennifer Mutch, Kaitlyn Ratkowiak, Stephen E Lemos, Kunal Kalra
PURPOSE: To describe the proximity of the lateral critical structures (peroneal nerve [PN], popliteus tendon [PT], lateral collateral ligament [LCL], and articular cartilage [AC]) to the femoral tunnel for outside-in all-epiphyseal anterior cruciate ligament (ACL) reconstruction in reference to knee flexion angle. METHODS: All-epiphyseal ACL reconstructions were performed in 12 human cadaveric knees using arthroscopy and outside-in drilling for anatomic femoral tunnel placement that was ensured by identifying the center of the total ACL footprint...
March 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28297913/intermediate-scattering-function-for-macromolecules-in-solutions-probed-by-neutron-spin-echo
#19
Yun Liu
The neutron-spin-echo method (NSE) is a powerful technique for studying internal dynamics of macromolecules in solutions because it can simultaneously probe length and time scales comparable to intramolecular density fluctuations of macromolecules. Recently, there has been increased, strong interest in studying protein internal motions using NSE. The coherent intermediate scattering function (ISF) measured by NSE depends on internal, rotational, and translational motions of macromolecules in solutions. It is thus critical, but highly nontrivial, to separate the internal motion from other motions in order to properly understand protein internal dynamics...
February 2017: Physical Review. E
https://www.readbyqxmd.com/read/28297865/numerical-study-of-nonequilibrium-gas-flow-in-a-microchannel-with-a-ratchet-surface
#20
Lianhua Zhu, Zhaoli Guo
The nonequilibrium gas flow in a two-dimensional microchannel with a ratchet surface and a moving wall is investigated numerically with a kinetic method [Guo et al., Phys. Rev. E 91, 033313 (2015)]PLEEE81539-375510.1103/PhysRevE.91.033313. The presence of periodic asymmetrical ratchet structures on the bottom wall of the channel and the temperature difference between the walls of the channel result in a thermally induced flow, and hence a tangential propelling force on the wall. Such thermally induced propelling mechanism can be utilized as a model heat engine...
February 2017: Physical Review. E
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