keyword
MENU ▼
Read by QxMD icon Read
search

Mixed state

keyword
https://www.readbyqxmd.com/read/28723731/the-combined-effect-of-cyp2b6-genotype-and-other-candidate-genes-on-a-steady-state-serum-concentration-of-methadone-in-opioid-maintenance-treatment
#1
Marianne K Kringen, Fatemeh Chalabianloo, Jean-Paul Bernard, Jørgen G Bramness, Espen Molden, Gudrun Høiseth
BACKGROUND: A considerable inter-individual variability in methadone pharmacokinetics is seen in patients on methadone maintenance treatment. The aim of this study was to clarify the impact of the reduced function CYP2B6*6 variant allele together with variants in other candidate genes on a steady-state methadone concentration in a naturalistic setting. METHODS: Information of methadone serum concentration, dose, age, gender and CYP2C9, CYP2C19, and CYP2D6 genotypes were collected from a routine therapeutic drug monitoring (TDM) database while variant alleles in CYP2B6 and CYP3A5 were retrospectively genotyped...
July 18, 2017: Therapeutic Drug Monitoring
https://www.readbyqxmd.com/read/28723221/accelerating-realtime-tddft-with-block-orthogonalized-manby-miller-embedding-theory
#2
Kevin J Koh, Triet S Nguyen-Beck, John Parkhill
Realtime time-dependent density-functional theory (RT-TDDFT) is one of the mostpractical techniques available to simulate electronic dynamics of molecules and mate-rials. Promising applications of RT-TDDFT to study non-linear spectra and energytransport, demand simulations of large solvated systems over long timescales, whichare computationally quite costly. In this paper, we apply an embedding techniquedeveloped for ground-state SCF methods by Manby and Miller to accelerate realtimeTDDFT. We assess the accuracy and speed of these approximations by studying theabsorption spectra of solvated and covalently split chromophores...
July 19, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28723082/mixed-valency-in-a-3d-semiconducting-iron-fluoranilate-coordination-polymer
#3
Ryuichi Murase, Brendan F Abrahams, Deanna M D'Alessandro, Casey G Davies, Timothy A Hudson, Guy N L Jameson, Boujemaa Moubaraki, Keith S Murray, Richard Robson, Ashley L Sutton
A pair of coordination polymers of composition (NBu4)2[M2(fan)3] (fan = fluoranilate; M = Fe and Zn) were synthesized and structurally characterized. In each case the compound consists of a pair of interpenetrating three-dimensional, (10,3)-a networks in which metal centers are linked by chelating/bridging fluoranilate ligands. Tetrabutylammonium cations are located in the spaces between the two networks. Despite the structural similarity, significant differences exist between (NBu4)2[Fe2(fan)3] and (NBu4)2[Zn2(fan)3] with respect to the oxidation states of the metal centers and ligands...
July 19, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28722816/construction-of-all-solid-state-batteries-based-on-sulfur-graphene-composite-and-li9-54si1-74p1-44s11-7cl0-3-solid-electrolyte
#4
Ruochen Xu, Zhang Wu, Shenzhao Zhang, Xiuli Wang, Yan Xia, Xinhui Xia, Xiaohua Huang, Jiangping Tu
Herein we report an effective way for construction of all-solid-state lithium-sulfur batteries (LSBs) with sulfur/reduced graphene oxide (rGO) and Li9.54Si1.74P1.44S11.7Cl0.3 solid electrolyte. In the composite cathode, the Li9.54Si1.74P1.44S11.7Cl0.3 powder is homogeneously mixed with the S/rGO composite to enhance the ionic conductivity. Coupled with metallic Li anode and solid electrolyte, the designed S/rGO-Li9.54Si1.74P1.44S11.7Cl0.3 composite cathode exhibits a high specific capacity and good cyclic stability...
July 19, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28722274/mixed-mood-the-not-so-united-states
#5
Gin S Malhi, Michael Berk, Grace Morris, Amber Hamilton, Tim Outhred, Pritha Das, Darryl Bassett, Bernhard T Baune, Philip Boyce, Bill Lyndon, Roger Mulder, Gordon Parker, Ajeet B Singh
No abstract text is available yet for this article.
June 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28722040/a-new-set-of-cd-ii-coordination-polymers-with-mixed-ligands-of-dicarboxylate-and-pyridyl-substituted-diaminotriazine-selective-sorption-towards-co2-and-cationic-dyes
#6
Santanu Chand, Syed Meheboob Elahi, Arun Pal, Madhab C Das
On the basis of a mixed ligand system of L(NH2)2 (6-(pyridin-4-yl)-1,3,5-triazine-2,4-diamine) and dicarboxylic acids, three new Cd(ii) coordination polymers viz. {[Cd0.5(tdc)0.5(L(NH2)2)0.5(H2O)]·DMF·H2O}n (1), {[Cd0.5(bdc)0.5(L(NH2)2)(H2O)]·DMF·H2O}n (2), and {[Cd(ipa)(L(NH2)2)(DMF)]·H2O}n (3) (tdcH2 = thiophene-2,5-dicarboxylic acid, bdcH2 = benzene-1,4-dicarboxylic acid, ipaH2 = benzene-1,3-dicarboxylic acid) were synthesized under diverse reaction conditions and characterized by single crystal X-ray diffraction, PXRD, elemental analysis, IR spectroscopy and TGA...
July 19, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28721495/diversity-and-survival-of-artificial-lifeforms-under-sedimentation-and-random-motion
#7
Nicolas Glade, Olivier Bastien, Pascal Ballet
Cellular automata are often used to explore the numerous possible scenarios of what could have occurred at the origins of life and before, during the prebiotic ages, when very simple molecules started to assemble and organise into larger catalytic or informative structures, or to simulate ecosystems. Artificial self-maintained spatial structures emerge in cellular automata and are often used to represent molecules or living organisms. They converge generally towards homogeneous stationary soups of still-life creatures...
July 18, 2017: Theory in Biosciences, Theorie in Den Biowissenschaften
https://www.readbyqxmd.com/read/28721187/individual-and-interactive-effects-of-white-tailed-deer-and-an-exotic-shrub-on-artificial-and-natural-regeneration-in-mixed-hardwood-forests
#8
Charlotte F Owings, Douglass F Jacobs, Joshua M Shields, Michael R Saunders, Michael A Jenkins
Underplanting tree seedlings in areas where natural regeneration is limited may offer a tool by which desired overstory composition can be maintained or restored in forests. However, invasive plant species and ungulate browsing may limit the effectiveness of underplanting, and in-turn, the successful restoration of forest ecosystems. Individually, the invasive shrub Lonicera maackii and browsing by white-tailed deer (Odocoileus virginianus) have been found to negatively affect the regeneration of native tree species in the Midwestern United States, but few studies have examined their interactive or cumulative effects...
July 2017: AoB Plants
https://www.readbyqxmd.com/read/28720873/bulk-vs-surface-structure-of-3d-metal-impurities-in-topological-insulator-bi2te3
#9
B Leedahl, D W Boukhvalov, E Z Kurmaev, A Kukharenko, I S Zhidkov, N V Gavrilov, S O Cholakh, P Huu Le, C Wei Luo, A Moewes
Topological insulators have become one of the most prominent research topics in materials science in recent years. Specifically, Bi2Te3 is one of the most promising for technological applications due to its conductive surface states and insulating bulk properties. Herein, we contrast the bulk and surface structural environments of dopant ions Cr, Mn, Fe, Co, Ni, and Cu in Bi2Te3 thin films in order to further elucidate this compound. Our measurements show the preferred oxidation state and surrounding crystal environment of each 3d-metal atomic species, and how they are incorporated into Bi2Te3...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28720626/family-physicians-perceptions-of-electronic-cigarettes-in-tobacco-use-counseling
#10
Samuel Ofei-Dodoo, Rick Kellerman, Kari Nilsen, Ruth Nutting, Douglas Lewis
BACKGROUND: Recent support has been shown for physicians to recommend e-cigarettes to patients who are trying to quit smoking. Supporters of this recommendation argue that e-cigarettes are not combustible products and are less harmful and more effective cessation products than regular cigarettes, with less inherent risk. Those who oppose this idea argue that little reliable evidence suggests that e-cigarettes are better cigarette cessation devices than currently available nicotine replacement therapies, and that they pose as much risk as cigarettes...
July 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28720140/a-mixed-methods-protocol-for-developing-and-testing-implementation-strategies-for-evidence-based-obesity-prevention-in-childcare-a-cluster-randomized-hybrid-type-iii-trial
#11
Taren Swindle, Susan L Johnson, Leanne Whiteside-Mansell, Geoffrey M Curran
BACKGROUND: Despite the potential to reach at-risk children in childcare, there is a significant gap between current practices and evidence-based obesity prevention in this setting. There are few investigations of the impact of implementation strategies on the uptake of evidence-based practices (EBPs) for obesity prevention and nutrition promotion. This study protocol describes a three-phase approach to developing and testing implementation strategies to support uptake of EBPs for obesity prevention practices in childcare (i...
July 18, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28719275/high-triatoma-brasiliensis-densities-and-trypanosoma-cruzi-prevalence-in-domestic-and-peridomestic-habitats-in-the-state-of-rio-grande-do-norte-brazil-the-source-for-chagas-disease-outbreaks
#12
Mauricio Lilioso, Elaine Folly-Ramos, Fabiana Lopes Rocha, Jorge Rabinovich, Claire Capdevielle-Dulac, Myriam Harry, Paula L Marcet, Jane Costa, Carlos Eduardo Almeida
AbstractA total of 2,431 Triatoma brasiliensis were collected from 39 populations of Paraíba (PB) and Rio Grande do Norte (RN) states, Brazil. In PB, Trypanosoma cruzi infection was not detected in either peridomestic or domestic vector populations. In contrast, in RN, T. brasiliensis was detected with high parasite prevalence in these ecotopes (30.7-40.0%). Moreover, peridomicile insect population densities were more than double the average densities of all other settings evaluated (19.17 versus < 8.94 triatomine/man-hour)...
June 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28718844/solvent-gradient-electrospray-for-laser-ablation-electrospray-ionization-mass-spectrometry
#13
Hang Li, Akos Vertes
Most electrospray based ambient ionization techniques, e.g., laser ablation electrospray ionization (LAESI), utilize a fixed spray solution composition. Complex samples often contain compounds of different polarity that exhibit a wide range of solubilities in the electrospray solvent. Thus, the fixed spray solution composition limits the molecular coverage of these approaches. Two-barrel theta glass capillaries have been used for the rapid mixing of two solutions for manipulating fast reactions including protein folding, unfolding, and charge state distributions...
July 18, 2017: Analyst
https://www.readbyqxmd.com/read/28716863/opposing-regulation-and-roles-for-phd3-in-lung-dendritic-cells-and-alveolar-macrophages
#14
Simon J Tavernier, Nele Vanlangenakker, Jessica Vetters, Peter Carmeliet, Sophie Janssens, Bart N Lambrecht
The prolyl hydroxylase domain-containing enzymes (PHDs) are important metabolic sensors of the cell and its environment, which might be employed to alert cells of the immune system. These enzymes regulate the expression of the hypoxia inducible factor (HIF) isoforms and NF-κB, crucial transcription factors controlling cellular metabolism and inflammation. PHD/HIF signaling is activated in the allergic lung and is proposed as a potential druggable pathway. Here, we investigated the regulation and role of the PHD isoforms in CD11c-expressing dendritic cells (DCs) and macrophages (Mϕ), sensors of the environment and crucial antigen-presenting cells in the pathogenesis of asthma...
July 17, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28716209/understanding-animal-health-communication-networks-among-smallholder-livestock-producers-in-australia-using-stakeholder-analysis
#15
L Hayes, R Woodgate, L Rast, J-A L M L Toribio, M Hernández-Jover
Smallholder livestock producers are a diverse population with wide ranging motivations for keeping livestock. The biosecurity risk posed by smallholders has been the subject of much conjecture, with comparisons often made between the level of animal health and biosecurity knowledge of smallholders, versus that of commercial livestock producers. This research aimed to gain a better understanding of current knowledge of smallholder production in Australia, particularly in relation to biosecurity and emergency animal disease, and to investigate the relationships that exist between smallholders and the organisations and individuals from which they seek information, assistance and support...
September 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28716009/prevalence-and-associated-risk-factors-of-malaria-among-adults-in-east-shewa-zone-of-oromia-regional-state-ethiopia-a-cross-sectional-study
#16
Frew Tadesse, Andrew W Fogarty, Wakgari Deressa
BACKGROUND: Malaria is one of the most important causes of morbidity and mortality in sub-Saharan Africa. The disease is prevalent in over 75% of the country's area making it the leading public health problems in the country. Information on the prevalence of malaria and its associated factors is vital to focus and improve malaria interventions. METHODS: A cross-sectional study was carried out from October to November 2012 in East Shewa zone of Oromia Regional State, Ethiopia...
July 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28715891/s-k-edge-xas-studies-of-the-effect-of-dna-binding-on-the-fe4s4-site-in-endoiii-and-muty
#17
Yang Ha, Anna R Arnold, Nicole N Nuñez, Phillip L Bartels, Andy Zhou, Sheila S David, Jacqueline K Barton, Britt Hedman, Keith O Hodgson, Edward I Solomon
S K-edge X-ray Absorption Spectroscopy (XAS) was used to study the [Fe4S4] clusters in the DNA repair glycosylases EndoIII and MutY to evaluate the effects of DNA binding and solvation on Fe-S bond covalencies (ie. the amount of S 3p character mixed into the Fe 3d valence orbitals). Increased covalencies in both iron-thiolate and iron-sulfide bonds would stabilize the oxidized state of the [Fe4S4] clusters. The results are compared to those on previously studied [Fe4S4] model complexes, ferredoxin (Fd), and to new data on high potential iron-sulfur protein (HiPIP)...
July 18, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28715810/population-pharmacokinetics-of-diazoxide-in-children-with-hyperinsulinemic-hypoglycemia
#18
Rika Kizu, Kazuko Nishimura, Reiko Sato, Kenjiro Kosaki, Toshiaki Tanaka, Yusuke Tanigawara, Tomonobu Hasegawa
BACKGROUND: Diazoxide is the first-line treatment for pediatric hyperinsulinemic hypoglycemia (HI). This study aimed to elucidate the pharmacokinetics of diazoxide in children with HI. METHODS: We obtained 81 blood samples from 22 children with HI. Measured serum diazoxide concentrations were used for population pharmacokinetic analysis. Patient factors influencing pharmacokinetics were estimated using nonlinear mixed-effects model analysis. Relationships between drug exposure and adverse drug reactions were also investigated...
July 14, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28715225/structure-ionic-conductivity-and-dielectric-properties-of-li-rich-garnet-type-li5-2xla3ta2-xsmxo12-0-%C3%A2-x-%C3%A2-0-55-and-their-chemical-stability
#19
Dalia M Abdel-Basset, Suresh Mulmi, Mohammed S El-Bana, Suzan S Fouad, Venkataraman Thangadurai
Lithium garnet oxides are considered as very promising solid electrolyte candidates for all-solid-state lithium ion batteries (SSLiBs). In this work, we present a cubic garnet-type Li5+2xLa3Ta2-xSmxO12 (0 ≤ x ≤ 0.55) system as a potential electrolyte for SSLiBs. Powder X-ray diffraction (PXRD) and scanning electron microscopy (SEM) were employed to investigate the structural stability of Li5+2xLa3Ta2-xSmxO12. The results from PXRD and SEM suggested structural and morphological transformation as a function of dopant concentration...
July 17, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28715222/photoluminescence-enhancement-through-symmetry-breaking-induced-by-defects-in-nanocrystals
#20
Peter C Sercel, Andrew Shabaev, Alexander Lev Efros
We present a theoretical model for the effect of symmetry breaking introduced by the doping of semiconductor nanocrystals with Coulomb impurities. The presence of a Coulomb center breaks the nanocrystal symmetry and affects its optical properties through mixing of the hole spin and parity sublevels, breaking the selection rules responsible for the exciton dark state in undoped nanocrystals. After reviewing the effects on the exciton fine structure and optical selection rules using symmetry theory, we present a perturbative model to quantify the effects...
July 17, 2017: Nano Letters
keyword
keyword
104250
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"