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https://www.readbyqxmd.com/read/28092410/big-five-personality-characteristics-are-associated-with-depression-subtypes-and-symptom-dimensions-of-depression-in-older-adults
#1
A M L Koorevaar, J M Hegeman, F Lamers, A D F Dhondt, R C van der Mast, M L Stek, H C Comijs
OBJECTIVE: This study examined the associations of personality characteristics with both subtypes and symptom dimensions of depression in older adults. METHODS: Three hundred and seventy-eight depressed older adults participated in the Netherlands Study of Depression in Older Persons. Personality characteristics were assessed by the NEO-Five Factor Inventory. Subtypes and symptom dimensions of depression were determined using the Composite International Diagnostic Interview and the Inventory of Depressive Symptomatology (IDS)...
January 16, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28091795/mood-spectrum-disorders-and-perception-of-pain
#2
Antonella Ciaramella
: Evaluation of pain perception in chronic pain patients with a concomitant mood-spectrum disorder. DESIGN: The observational retrospective study is based on patient data collected in psychosomatic consultations held at the Gift Institute for Integrative Medicine in Pisa, Italy, from 2002 to 2014. Evoked pain stimulus threshold and tolerance were evaluated using the cold pressor test. Clinical pain intensity and Sensorial, Affective, and Evaluative dimensions were assessed using the Italian Pain Questionnaire, and Anxiety and Depressive symptoms using the Hospital Anxiety Depression Scale...
January 14, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28027956/neuropsychological-changes-in-melancholic-and-atypical-depression-a-systematic-review
#3
REVIEW
Nayanne Beckmann Bosaipo, Maria Paula Foss, Allan H Young, Mario Francisco Juruena
There is not a consensus as to whether neuropsychological profiling can distinguish depressive subtypes. We aimed to systematically review and critically analyse the literature on cognitive function in patients with melancholic and atypical depression. We searched in databases PubMed, SCOPUS, Web of Knowledge and PsycInfo for papers comparing the neuropsychological performance of melancholic patients (MEL) to non-melancholic depressive patients (NMEL), including atypical depressives, and healthy controls (HC)...
December 24, 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27989405/aberrant-default-mode-network-homogeneity-in-patients-with-first-episode-treatment-naive-melancholic-depression
#4
Xilong Cui, Wenbin Guo, Yi Wang, Tian-Xiao Yang, Xin-Hua Yang, Yefei Wang, Jingbo Gong, Changlian Tan, Guangrong Xie
BACKGROUND: Melancholic depression is a relatively homogenous subtype of major depressive disorders (MDD). The condition has several endogenous symptoms and represents strong biological components. However, its specific neurobiological mechanisms remain unknown. Previous neuroimaging findings indicated that default mode network (DMN) is closely related to MDD. The present study examined the network homogeneity (NH) of the DMN in patients with melancholic MDD. METHODS: A total of 33 first-episode, treatment-naive melancholic MDD patients and 32 healthy controls underwent a resting-state functional magnetic resonance imaging scan...
February 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/27987214/targeting-and-transforming-major-depression
#5
G Parker, A Paterson, S McCraw, D Hadzi-Pavlovic
OBJECTIVE: To detail limitations to the construct of 'major depression', argue for repositioning it as a proxy for 'clinical depression' and then operationalize it and its principal constituent depressive subtypes, while preserving the DSM criteria-based format. METHOD: We summarize limitations to major depression being viewed as a diagnostic entity. Data from 391 clinically depressed patients were analysed to identify high-prevalence non-specific depressive symptoms to define 'clinical depression' as well as the features showing specificity to a melancholic depressive subtype...
December 16, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27966795/the-so-called-death-drive-an-indispensable-force-for-any-subjective-life
#6
Bernard Penot
The psychoanalytic movement has difficulty in overcoming the malaise bequeathed by what Freud wanted to call the 'death drive'. This term remains doubly problematic: first because the indispensable antagonist of Eros-binding cannot be reduced to a particular drive; and secondly because this Anteros plays a vital role in subjectivization. The Freudian idea of the 'death drive' has in addition the drawback of confusing dissociative thrust (unbinding) with the aggressive component of libidinal cathexis. Now it is precisely the lack of articulation between them that leads to deconstructing it...
December 14, 2016: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/27921338/melancholic-and-atypical-depression-as-predictor-and-moderator-of-outcome-in-cognitive-behavior-therapy-and-pharmacotherapy-for-adult-depression
#7
Pim Cuijpers, Erica Weitz, Femke Lamers, Brenda W Penninx, Jos Twisk, Robert J DeRubeis, Sona Dimidjian, Boadie W Dunlop, Robin B Jarrett, Zindel V Segal, Steven D Hollon
BACKGROUND: Melancholic and atypical depression are widely thought to moderate or predict outcome of pharmacological and psychological treatments of adult depression, but that has not yet been established. This study uses the data from four earlier trials comparing cognitive behavior therapy (CBT) versus antidepressant medications (ADMs; and pill placebo when available) to examine the extent to which melancholic and atypical depression moderate or predict outcome in an "individual patient data" meta-analysis...
December 6, 2016: Depression and Anxiety
https://www.readbyqxmd.com/read/27836011/a-naturalistic-study-of-high-dose-unilateral-ect-among-severely-depressed-inpatients-how-does-it-work-in-the-clinical-practice
#8
Lucas P C Alves, Thiago F V Freire, Marcelo P A Fleck, Neusa S Rocha
BACKGROUND: Naturalistic studies can be useful tools to understand how an intervention works in the real clinical practice. This study aims to investigate the outcomes in a naturalistically treated depressed inpatients cohort, who were referred, or not, to unilateral ECT. METHODS: Depressed adults according to MINI admitted in a psychiatric unit were divided in unilateral ECT treated and non-ECT treated. Main outcomes were: depression improvement in Hamilton Rating Scale for Depression (HDRS-17) scores; response (HDRS-17 improvement ≥50 %); remission (HDRS-17 score ≤7); length of hospitalization...
November 11, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27793702/clinical-and-biological-predictors-of-response-to-electroconvulsive-therapy-ect-a-review
#9
REVIEW
Martina Pinna, Mirko Manchia, Rossana Oppo, Filomena Scano, Gianluca Pillai, Anna Paola Loche, Piergiorgio Salis, Gian Paolo Minnai
Electroconvulsive therapy (ECT), developed in the 30's by Bini and Cerletti, remains a key element of the therapeutic armamentarium in psychiatry, particularly for severe and life-threatening psychiatric symptoms. However, despite its well-established clinical efficacy, the prescription of ECT has declined constantly over the years due to concerns over its safety (cognitive side effects) and an increasingly negative public perception. As for other treatments in the field of psychiatry, ECT is well suited to a personalized approach that would increment its efficacy, as well as reducing the impact of side effects...
October 25, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27768745/anterograde-amnesia-during-electroconvulsive-therapy-a-prospective-pilot-study-in-patients-with-major-depressive-disorder
#10
Elvira Boere, Astrid M Kamperman, Arianne E van 't Hoog, Walter W van den Broek, Tom K Birkenhäger
Electroconvulsive therapy (ECT) is considered an effective treatment for major depression with melancholic features. However, neurocognitive side-effects such as anterograde amnesia still regularly occur. The present study aims to evaluate the severity and course of anterograde amnesia in severely depressed patients undergoing ECT. In a prospective naturalistic study, anterograde memory function was assessed among inpatients who underwent ECT (n = 11). Subjects met DSM-IV criteria for major depressive disorder...
2016: PloS One
https://www.readbyqxmd.com/read/27756252/disappearance-of-treatment-resistant-depression-after-damage-to-the-orbitofrontal-cortex-and-subgenual-cingulate-area-a-case-study
#11
Michitaka Funayama, Motoichiro Kato, Masaru Mimura
BACKGROUND: Although post-stroke depression is a well-characterized disorder, there is less understanding of how pre-existence of depression is affected by a stroke. CASE PRESENTATION: We describe a patient with treatment-resistant major depression, which had been ongoing for 14 years but disappeared shortly after onset of a subarachnoid hemorrhage. Her cognitive function and functional status were mostly unaffected by the stroke. However, she no longer excessively regretted past events...
October 19, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27725658/prospective-associations-of-depression-subtypes-with-cardio-metabolic-risk-factors-in-the-general-population
#12
A M Lasserre, M-P F Strippoli, J Glaus, M Gholam-Rezaee, C L Vandeleur, E Castelao, P Marques-Vidal, G Waeber, P Vollenweider, M Preisig
The mechanisms and temporal sequence underlying the association between major depressive disorder (MDD) and cardio-metabolic diseases are still poorly understood. Recent research suggests subtyping depression to study the mechanisms underlying its association with biological correlates. Accordingly, our aims were to (1) assess the prospective associations of the atypical, melancholic and unspecified subtypes of MDD with changes of fasting glucose, high-density lipoprotein-cholesterol, triglycerides, systolic blood pressure and the incidence of the metabolic syndrome, (2) determine the potential mediating role of inflammatory marker or adipokine concentrations, eating behaviors and changes in waist circumference during follow-up...
October 11, 2016: Molecular Psychiatry
https://www.readbyqxmd.com/read/27721186/the-properties-and-utility-of-the-core-measure-of-melancholia
#13
REVIEW
Gordon Parker, Stacey McCraw
BACKGROUND: The CORE measure was designed to assess a central feature of melancholia - signs of psychomotor disturbance (PMD) - and so provide an alternate non-symptom based measure of melancholia or of its probability. This review evaluates development and application studies undertaken over the last 25 years to consider how well it has met its original objectives. METHODS: All studies published using the CORE measure as either the only or an adjunctive measure of melancholia were obtained and are considered in this review...
January 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27660275/associations-of-serum-cytokine-receptor-levels-with-melancholia-staging-of-illness-depressive-and-manic-phases-and-severity-of-depression-in-bipolar-disorder
#14
Marcin Siwek, Magdalena Sowa-Kućma, Krzysztof Styczeń, Paulina Misztak, Rafał J Nowak, Bernadeta Szewczyk, Dominika Dudek, Janusz K Rybakowski, Gabriel Nowak, Michael Maes
To examine cytokine receptor biomarkers in bipolar disorder (BD), we recruited 133 well-phenotyped BD patients and 50 normal controls and measured serum levels of soluble interleukin 1 receptor antagonist (sIL-1RA), soluble interleukin-2 receptor (sIL-2R), sIL-6R, and tumor necrosis factor receptor 60 and 80 kDa (sTNFR60/80). sIL-1RA and sTNFR80 are significantly higher in BD than in controls and sTNFR80 and higher in melancholic than in non-melancholic patients and controls. Kapczinski's stages 3 + 4 are characterized by lowered sIL-2R and increased sTNFR80 levels...
September 23, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27658988/-homicide-suicide-clinical-review-and-psychological-assumptions
#15
J Vandevoorde, N Estano, G Painset
OBJECTIVES: Suicide-homicide could be defined as a "suicidal" behaviour, which also includes the death of at least one other individual and sometimes up to hundreds. This literature review intends to highlight some characteristic features that might be found amongst the various types of suicide-homicide. It is a complex phenomenon which can occur in different situations, from a familial and somehow intimate setting (filicide, uxoricide, marital homicide…) to a public one (workplace shooting, school shooting), including a wide range of victims, from a single victim in marital cases of suicide-homicide to hundreds of victims in certain types, such as suicide by aircraft or warrior-like multi-homicids in terrorist acts...
September 19, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27631307/-i-don-t-have-time-for-an-emotional-life-marginalization-dependency-and-melancholic-suspension-in-disability
#16
Brian Watermeyer
Social scientific analyses of inequality inform interventions ranging from the material and political to the personal and psychological. At the extremes of this continuum, Marxian militants view the exploration of the inner lives of oppressed people as irrelevant to liberation, while psychoanalysts bemoan the naïveté of "depsychologized" conceptions of the social subject. While both approaches have been applied to disability inequality, an historical materialist view has dominated the discipline of disability studies, where attention has only recently turned to psychological aspects of oppression...
September 8, 2016: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/27571994/a-comparison-of-perceptions-of-modern-type-and-melancholic-depression-in-japan
#17
Shinji Sakamoto, Itsuki Yamakawa, Masaki Muranaka
BACKGROUND: In Japan, psychiatrists have noted two different types of depression, traditional/melancholic depression and 'modern-type' depression (MTD). Although both the modern and the traditional types of depression overlap in regard to symptoms, these are two distinct syndromes, which can lead to confusion for Japanese people. AIMS: This study aims to examine impressions of two types of depression using vignettes and clarify the differences in perceptions of the two types...
August 29, 2016: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/27569105/melancholy-as-a-risk-factor-for-cancer-a-historical-overview
#18
Marianna Karamanou, Elias Tzavellas, Konstantinos Laios, Michalis Koutsilieris, George Androutsos
In antiquity, physicians related depression or melancholic humour to cancer's pathogenesis. Galen (130-201 AD), sustained that melancholy could give rise to a tumour and his theory was repeated by the Byzantine and Arab physicians. In the 19th century, malignancy and depression became synonymous and people attributed their cancer to sadness. In 1893, the London surgeon Hebert Snow (1847-1930), performed an epidemiological study in order to clarify that link. The results revealed a probable connection. His work was followed by several large scale prospective studies some of which identified depression as a risk factor for cancer where others found no association...
May 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/27550955/musculoskeletal-pain-in-melancholic-and-atypical-depression
#19
Katariina Korniloff, Satu Kotiaho, Mauno Vanhala, Hannu Kautiainen, Hannu Koponen, Pekka Mäntyselkä
OBJECTIVE:  Pain and depressive disorders often present together, but little is known about the prevalence of pain in depression subgroups. The objective of this study was to examine the possible differences in the prevalence of musculoskeletal pain between participants in melancholic and atypical depression subgroups. DESIGN:  Cross-sectional study. SETTING:  Depression nurse case managers where depression patients receive treatment in primary health care...
August 22, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27549765/metabolomic-biosignature-differentiates-melancholic-depressive-patients-from-healthy-controls
#20
Yashu Liu, Lynn Yieh, Tao Yang, Wilhelmus Drinkenburg, Pieter Peeters, Thomas Steckler, Vaibhav A Narayan, Gayle Wittenberg, Jieping Ye
BACKGROUND: Major depressive disorder (MDD) is a heterogeneous disease at the level of clinical symptoms, and this heterogeneity is likely reflected at the level of biology. Two clinical subtypes within MDD that have garnered interest are "melancholic depression" and "anxious depression". Metabolomics enables us to characterize hundreds of small molecules that comprise the metabolome, and recent work suggests the blood metabolome may be able to inform treatment decisions for MDD, however work is at an early stage...
2016: BMC Genomics
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