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https://www.readbyqxmd.com/read/28426426/pseudopecoelus-mccauleyi-n-sp-and-podocotyle-sp-digenea-opecoelidae-from-the-deep-waters-off-oregon-and-british-columbia-with-an-updated-key-to-the-species-of-pseudopecoelus-von-wicklen-1946-and-checklist-of-parasites-from-lycodes-cortezianus-perciformes-zoarcidae
#1
REVIEW
Charles K Blend, Norman O Dronen, Gabor R Racz, Scott L Gardner
Pseudopecoelus mccauleyi n. sp. (Opecoelidae: Opecoelinae) is described from the intestine of the bigfin eelpout, Lycodes cortezianus (Gilbert, 1890) (Perciformes: Zoarcidae), collected at 200-800 m depths in the Northeastern Pacific Ocean off Oregon and Vancouver Island, British Columbia. The new species is distinguished by possessing a unique combination of the following diagnostic characters: vitelline fields that extend to the posterior margin of the ventral sucker; a slender, tubular and sinuous seminal vesicle that extends some distance into the hindbody; an unspecialized, protuberant ventral sucker; a genital pore at pharynx level; lobed to deeply multilobed testes; a lobed ovary; and an egg size of 68-80 μm × 30-46 μm...
June 1, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/28425222/class-iii-antiarrhythmic-drugs-amiodarone-and-dronedarone-impair-kir-2-1-backward-trafficking
#2
Yuan Ji, Hiroki Takanari, Muge Qile, Lukas Nalos, Marien J C Houtman, Fee L Romunde, Raimond Heukers, Paul M P van Bergen En Henegouwen, Marc A Vos, Marcel A G van der Heyden
Drug-induced ion channel trafficking disturbance can cause cardiac arrhythmias. The subcellular level at which drugs interfere in trafficking pathways is largely unknown. KIR 2.1 inward rectifier channels, largely responsible for the cardiac inward rectifier current (IK1 ), are degraded in lysosomes. Amiodarone and dronedarone are class III antiarrhythmics. Chronic use of amiodarone, and to a lesser extent dronedarone, causes serious adverse effects to several organs and tissue types, including the heart. Both drugs have been described to interfere in the late-endosome/lysosome system...
April 19, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28421566/precision-global-health-in-the-digital-age
#3
Antoine Flahault, Antoine Geissbuhler, Idris Guessous, Philippe Guérin, Isabelle Bolon, Marcel Salathé, Gérard Escher
Precision global health is an approach similar to precision medicine, which facilitates, through innovation and technology, better targeting of public health interventions on a global scale, for the purpose of maximising their effectiveness and relevance. Illustrative examples include: the use of remote sensing data to fight vector-borne diseases; large databases of genomic sequences of foodborne pathogens helping to identify origins of outbreaks; social networks and internet search engines for tracking communicable diseases; cell phone data in humanitarian actions; drones to deliver healthcare services in remote and secluded areas...
April 19, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28381818/dronedarone-attenuates-the-duration-of-atrial-fibrillation-in-a-dog-model-of-sustained-atrial-fibrillation
#4
Nakkawee Saengklub, Vudhiporn Limprasutr, Suwanakiet Sawangkoon, Robert L Hamlin, Anusak Kijtawornrat
Atrial fibrillation (AF) is a supraventricular arrhythmia that leads to a decrease in cardiac output and impairs cardiac function and quality of life. Dronedarone has an atrial-selective property and has been used for management of AF in humans, but limited information is available in dogs. This study was designed to evaluate efficacy of dronedarone in attenuating the duration of AF in dog model of sustained AF. Six beagle dogs were anesthetized with isoflurane and instrumented to measure atrial action potential duration (aAPD) and atrial effective refractory period (AERP)...
April 4, 2017: Experimental Animals
https://www.readbyqxmd.com/read/28318989/first-report-of-using-portable-unmanned-aircraft-systems-drones-for-search-and-rescue
#5
Christopher Van Tilburg
Unmanned aircraft systems (UAS), colloquially called drones, are used commonly for military, government, and civilian purposes, including both commercial and consumer applications. During a search and rescue mission in Oregon, a UAS was used to confirm a fatality in a slot canyon; this eliminated the need for a dangerous rappel at night by rescue personnel. A second search mission in Oregon used several UAS to clear terrain. This allowed search of areas that were not accessible or were difficult to clear by ground personnel...
March 16, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28277512/technology-insects-inspire-crash-proof-drone
#6
(no author information available yet)
No abstract text is available yet for this article.
March 8, 2017: Nature
https://www.readbyqxmd.com/read/28272421/eeg-frequency-tagging-dissociates-between-neural-processing-of-motion-synchrony-and-human-quality-of-multiple-point-light-dancers
#7
Nihan Alp, Andrey R Nikolaev, Johan Wagemans, Naoki Kogo
Do we perceive a group of dancers moving in synchrony differently from a group of drones flying in-sync? The brain has dedicated networks for perception of coherent motion and interacting human bodies. However, it is unclear to what extent the underlying neural mechanisms overlap. Here we delineate these mechanisms by independently manipulating the degree of motion synchrony and the humanoid quality of multiple point-light displays (PLDs). Four PLDs moving within a group were changing contrast in cycles of fixed frequencies, which permits the identification of the neural processes that are tagged by these frequencies...
March 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28254836/optimizing-a-drone-network-to-deliver-automated-external-defibrillators
#8
Justin J Boutilier, Steven C Brooks, Alyf Janmohamed, Adam Byers, Jason E Buick, Cathy Zhan, Angela P Schoellig, Sheldon Cheskes, Laurie J Morrison, Timothy C Y Chan
Background -Public access defibrillation programs can improve survival after out-of-hospital cardiac arrest (OHCA), but automated external defibrillators (AEDs) are rarely available for bystander use at the scene. Drones are an emerging technology that can deliver an AED to the scene of an OHCA for bystander use. We hypothesize that a drone network designed with the aid of a mathematical model combining both optimization and queuing can reduce the time to AED arrival. Methods -We applied our model to 53,702 OHCAs that occurred in the eight regions of the Toronto Regional RescuNET between January 1st 2006 and December 31st 2014...
March 2, 2017: Circulation
https://www.readbyqxmd.com/read/28246646/3d-printed-eagle-eye-compound-microlens-system-for-foveated-imaging
#9
Simon Thiele, Kathrin Arzenbacher, Timo Gissibl, Harald Giessen, Alois M Herkommer
We present a highly miniaturized camera, mimicking the natural vision of predators, by 3D-printing different multilens objectives directly onto a complementary metal-oxide semiconductor (CMOS) image sensor. Our system combines four printed doublet lenses with different focal lengths (equivalent to f = 31 to 123 mm for a 35-mm film) in a 2 × 2 arrangement to achieve a full field of view of 70° with an increasing angular resolution of up to 2 cycles/deg field of view in the center of the image. The footprint of the optics on the chip is below 300 μm × 300 μm, whereas their height is <200 μm...
February 2017: Science Advances
https://www.readbyqxmd.com/read/28238947/identification-of-novel-mrp3-inhibitors-based-on-computational-models-and-validation-using-an-in-vitro-membrane-vesicle-assay
#10
Izna Ali, Matthew A Welch, Yang Lu, Peter W Swaan, Kim L R Brouwer
INTRODUCTION: Multidrug resistance-associated protein 3 (MRP3), an efflux transporter on the hepatic basolateral membrane, may function as a compensatory mechanism to prevent the accumulation of anionic substrates (e.g., bile acids) in hepatocytes. Inhibition of MRP3 may disrupt bile acid homeostasis and is one hypothesized risk factor for the development of drug-induced liver injury (DILI). Therefore, identifying potential MRP3 inhibitors could help mitigate the occurrence of DILI. METHODS: Bayesian models were developed using MRP3 transporter inhibition data for 86 structurally diverse drugs...
February 24, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28229261/revision-of-neolebouria-gibson-1976-digenea-opecoelidae-with-trilobovarium-n-g-for-species-infecting-tropical-and-subtropical-shallow-water-fishes
#11
Storm B Martin, Scott C Cutmore, Thomas H Cribb
A new opecoelid trematode is reported from fishes of the Lethrinidae, Lutjanidae and Nemipteridae off Lizard Island on the northern Great Barrier Reef, Australia. The new species keys to Neolebouria Gibson, 1976 and shows strong similarity to several species of that genus, but is not consistent with the type-species, N. georgiensis Gibson, 1976, or others known from temperate/polar and/or deep-sea fishes. The new species is also phylogenetically distant from N. lanceolata (Price, 1934) Reimer, 1987, the only representative of the genus for which molecular data are available...
March 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28224659/assessment-of-the-toxicity-of-pesticides-on-honey-bee-drone-fertility-using-laboratory-and-semi-field-approaches-a-case-study-of-fipronil
#12
Guillaume Kairo, Yannick Poquet, Haïthem Haji, Sylvie Tchamitchian, Marianne Cousin, Marc Bonnet, Michel Pelissier, André Kretzschmar, Luc P Belzunces, Jean-Luc Brunet
Concern about the reproductive toxicity of plant protection products (PPPs) in honey bee reproducers is increasing. Because the reproductive capacity of honey bees is not currently considered during the risk assessment procedures performed during PPP registration, it is important to provide methods to assess such potential impairments. To achieve this aim, we used two different approaches that involved semi-field (SF) and laboratory (Lab) conditions to study the impact of Fipronil on drone fertility. For each approach, the drones were reared for 20 days, from emergence to sexual maturity, and exposed to Fipronil via a contaminated sugar solution...
February 22, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28163882/bioinspired-morphing-wings-for-extended-flight-envelope-and-roll-control-of-small-drones
#13
M Di Luca, S Mintchev, G Heitz, F Noca, D Floreano
Small-winged drones can face highly varied aerodynamic requirements, such as high manoeuvrability for flight among obstacles and high wind resistance for constant ground speed against strong headwinds that cannot all be optimally addressed by a single aerodynamic profile. Several bird species solve this problem by changing the shape of their wings to adapt to the different aerodynamic requirements. Here, we describe a novel morphing wing design composed of artificial feathers that can rapidly modify its geometry to fulfil different aerodynamic requirements...
February 6, 2017: Interface Focus
https://www.readbyqxmd.com/read/28160722/molecular-modeling-simulation-and-docking-study-of-ebola-virus-glycoprotein
#14
Nasir Ahmad, Aqsa Farman, Syed Lal Badshah, Ata Ur Rahman, Haroon Ur Rashid, Khalid Khan
Ebola virus (EBOV) is a filamentous, enveloped, non-segmented, negative-strand ribonucleic acid (RNA) virus which belongs to family Filoviridae. Ebola virus includes different glycoproteins each of which plays their roles in different aspects of viral life cycle. In this study secreted glycoprotein (Q7T9E0) of Ebola virus was acquired from Uniprot. The formation of alpha helix and beta sheets of secondary structures were predicted through online servers. Higher flexibility and disordered regions of proteins were determined through RONN, GLOBPLOT and DISSEMBLE...
March 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28159187/look-up-in-the-sky-it-s-a-bird-it-s-a-plane-it-s-a-medical-drone
#15
EDITORIAL
The Lancet Haematology
No abstract text is available yet for this article.
February 2017: Lancet Haematology
https://www.readbyqxmd.com/read/28150219/sexual-response-of-male-drosophila-to-honey-bee-queen-mandibular-pheromone-implications-for-genetic-studies-of-social-insects
#16
Justin R Croft, Tom Liu, Alison L Camiletti, Anne F Simon, Graham J Thompson
Honey bees secrete a queen mandibular pheromone that renders workers reproductively altruistic and drones sexually attentive. This sex-specific function of QMP may have evolved from a sexually dimorphic signaling mechanism derived from pre-social ancestors. If so, there is potential for pre-social insects to respond to QMP, and in a manner that is comparable to its normal effect on workers and drones. Remarkably, QMP applied to female Drosophila does induce worker-like qualities [Camiletti et al. (Entomol Exp Appl 147:262, 2013)], and we here extend this comparison to examine the effects of bee pheromone on male fruit flies...
February 1, 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/28135666/the-combined-effects-of-a-monotonous-diet-and-exposure-to-thiamethoxam-on-the-performance-of-bumblebee-micro-colonies
#17
C Dance, C Botías, D Goulson
There is a pressing need to better understand the factors contributing to declines of wild pollinators such as bumblebees. Many different contributors have been postulated including: loss of flower-rich habitats and nesting sites; monotonous diets; impacts of invasive pathogens; exposure to pesticides such as neonicotinoids. Past research has tended to investigate the impacts of these stressors in isolation, despite the increasing recognition that bees are simultaneously exposed to a combination of stressors, with potentially additive or synergistic effects...
January 27, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28110000/drones-may-be-used-to-save-lives-in-out-of-hospital-cardiac-arrest-due-to-drowning
#18
A Claesson, L Svensson, P Nordberg, M Ringh, M Rosenqvist, T Djarv, J Samuelsson, O Hernborg, P Dahlbom, A Jansson, J Hollenberg
BACKGROUND: Drowning leading to out-of-hospital cardiac arrest (OHCA) and death is a major public health concern. Submersion with duration of less than 10min is associated with favorable neurological outcome and nearby bystanders play a considerable role in rescue and resuscitation. Drones can provide a visual overview of an accident scene, their potential as lifesaving tools in drowning has not been evaluated. AIM: The aim of this simulation study was to evaluate the efficiency of a drone for providing earlier location of a submerged possible drowning victim in comparison with standard procedure...
January 18, 2017: Resuscitation
https://www.readbyqxmd.com/read/28107354/visual-adaptations-for-mate-detection-in-the-male-carpenter-bee-xylocopa-tenuiscapa
#19
Hema Somanathan, Renee Maria Borges, Eric J Warrant, Almut Kelber
Sexual dimorphism in eye structure is attributed to sexual selection in animals that employ vision for locating mates. In many male insects, large eyes and eye regions of higher acuity are believed to facilitate the location of females. Here, we compare various features of male and female eyes in three sympatric carpenter bee species, which include two diurnal species (Xylocopa tenuiscapa and X. leucothorax) as well as a nocturnal species (X. tranquebarica). In X. tenuiscapa, males have larger eyes than females, while in the nocturnal X...
2017: PloS One
https://www.readbyqxmd.com/read/28088225/using-low-cost-drones-to-map-malaria-vector-habitats
#20
Andy Hardy, Makame Makame, Dónall Cross, Silas Majambere, Mwinyi Msellem
BACKGROUND: There is a growing awareness that if we are to achieve the ambitious goal of malaria elimination, we must compliment indoor-based vector control interventions (such as bednets and indoor spraying) with outdoor-based interventions such as larval source management (LSM). The effectiveness of LSM is limited by our capacity to identify and map mosquito aquatic habitats. This study provides a proof of concept for the use of a low-cost (< $1000) drone (DJI Phantom) for mapping water bodies in seven sites across Zanzibar including natural water bodies, irrigated and non-irrigated rice paddies, peri-urban and urban locations...
January 14, 2017: Parasites & Vectors
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