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https://www.readbyqxmd.com/read/29682690/priorities-of-a-good-death-according-to-cancer-patients-their-family-caregivers-physicians-and-the-general-population-a-nationwide-survey
#1
Young Ho Yun, Kyoung-Nam Kim, Jin-Ah Sim, EunKyo Kang, Jihye Lee, Jiyeon Choo, Shin Hye Yoo, Miso Kim, Young Ae Kim, Beo Deul Kang, Hyun-Jeong Shim, Eun-Kee Song, Jung Hun Kang, Jung Hye Kwon, Jung Lim Lee, Soon Nam Lee, Chi Hoon Maeng, Eun Joo Kang, Young Rok Do, Yoon Seok Choi, Kyung Hae Jung
PURPOSE: Understanding the concept of a "good death" is crucial to end-of-life care, but our current understanding of what constitutes a good death is insufficient. Here, we investigated the components of a good death that are important to the general population, cancer patients, their families, and physicians. METHODS: We conducted a stratified nationwide cross-sectional survey of cancer patients and their families from 12 hospitals, physicians from 12 hospitals and the Korean Medical Association, and the general population, investigating their attitudes toward 10 good-death components...
April 22, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29572851/mortality-and-functional-outcomes-after-minor-urological-surgery-in-nursing-home-residents-a-national-study
#2
Anne M Suskind, Shoujun Zhao, Louise C Walter, W John Boscardin, Emily Finlayson
OBJECTIVES: To determine outcomes of minor urological surgery in frail older adults. DESIGN: Retrospective cohort study. SETTING: U.S. nursing homes (NHs). PARTICIPANTS: NH residents aged 65 and older undergoing minor inpatient urological surgery (cystoscopy, bladder biopsy, transurethral resection of bladder tumor, prostate biopsy, transurethral resection of prostate, removal of ureteral obstruction, suprapubic tube placement) in the United States between 2004 and 2012 (N=34,605)...
March 23, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29345106/national-study-of-the-nutritional-status-of-korean-older-adults-with-dementia-who-are-living-in-long-term-care-settings
#3
Myonghwa Park, Jun-Ah Song, Mihyun Lee, Hyun Jeong, Soyeun Lim, Haejung Lee, Chun-Gill Kim, Jeong S Kim, Kyung S Kim, Young W Lee, Young M Lim, Young S Park, Jong C Yoon, Ki W Kim, Gwi-Ryung S Hong
AIM: To evaluate the nutritional status of older adults with dementia who were living in long-term care settings. METHODS: As a secondary analysis, this study used the data from the Nationwide Survey on Dementia Care in Korea that was conducted between December 1, 2010, and August 31, 2011, which surveyed 3472 older adults with dementia, aged ≥60 years (mean age: 81.24 years), who were residing in 248 randomly selected long-term care settings in South Korea...
January 17, 2018: Japan Journal of Nursing Science: JJNS
https://www.readbyqxmd.com/read/29249738/factors-contributing-to-the-self-reported-prevalence-of-multiple-chemical-sensitivity-in-public-facility-workers-and-the-general-population-of-korea
#4
Yong Heo, Sang-Hoon Kim, Seok-Ki Lee, Hyoung-Ah Kim
Multiple chemical sensitivity (MCS), an acquired disorder with multiple recurrent symptoms, has been studied for its association with diverse environmental factors. The present study investigated the factors associated with the self-reported prevalence of MCS in public facility workers and the general population in Korea. The Quick Environmental Exposure Sensitivity Inventory (QEESI) questionnaire was obtained from public facility workers (N=530) and the general population (N=500) to determine the prevalence of MCS and the degree of its risk...
2017: Journal of UOEH
https://www.readbyqxmd.com/read/29041879/-adherence-to-therapy-in-the-outpatient-setting-the-ability-to-identify-and-assess-the-effectiveness-of-therapy
#5
T F Ageev, D M Smirnova, D A Deev, V T Fofanova
AIM: To assess adherence of patients to antihypertensive therapy, to determine the role of various factors affecting adherence to treatment by outpatients, and to assess clinical efficacy of a calcium antagonist felodipine. MATERIAL AND METHODS: We examined 5 474 women and men aged >18 years who at visit to a local internist had office systolic arterial pressure (AP) 140-179 and diastolic AP up to 100 mm Hg both on and without hypotensive therapy. Examination included registration of risk factors and concomitant therapy...
July 2017: Kardiologiia
https://www.readbyqxmd.com/read/29021825/suicidal-deaths-in-elementary-school-students-in-korea
#6
Minha Hong, Han Nah Cho, Ah Reum Kim, Hyun Ju Hong, Yong-Sil Kweon
BACKGROUND: The purpose of this study was to determine the characteristics of childhood suicidal deaths among elementary school students that occurred from 2011 to 2015 in Korea. METHODS: The report form of each suicide case by the teacher in charge to the Education Ministry was reviewed retrospectively. RESULTS: There were 19 suicidal deaths (12 boys, 7 girls) in elementary school students. The youngest case was a third grader (n = 1). Jumping from heights (n = 12) was the most frequently used method...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/28916946/association-between-placental-polycyclic-aromatic-hydrocarbons-pahs-oxidative-stress-and-preterm-delivery-a-case-control-study
#7
Priyanka Agarwal, Laxmi Singh, Madhu Anand, Ajay Taneja
Polycyclic aromatic hydrocarbons are known to disturb the antioxidant defense system, which may indirectly contribute to induction of early pregnancy in women. Therefore, the present investigation was designed to offer preliminary information about exposure to PAHs by estimating their placental levels and its association with oxidative stress as well as with preterm birth. Placenta tissue samples were drawn after delivery from 84 healthy pregnant women, recruited at a local nursing home of Agra, India, and levels of PAHs were quantified by gas chromatograph equipped with flame ionization detector...
February 2018: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28885755/effects-of-an-individualised-nutritional-education-and-support-programme-on-dietary-habits-nutritional-knowledge-and-nutritional-status-of-older-adults-living-alone
#8
Jeong-Ah Ahn, JeeWon Park, Chun-Ja Kim
AIMS AND OBJECTIVES: The effects of an individualised nutritional education and support programme on dietary habits, nutritional knowledge and nutritional status of 71 older adults living alone were examined. BACKGROUND: Although a regular dietary meal plan is recommended for improving nutritional status of older adults living alone, little research is done in this field in Korea. DESIGN: A pre- and post-test controlled quasi-experimental design was used at public health centres...
September 7, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28860717/development-of-idursulfase-therapy-for-mucopolysaccharidosis-type-ii-hunter-syndrome-the-past-the-present-and-the-future
#9
REVIEW
David Ah Whiteman, Alan Kimura
Mucopolysaccharidosis type II (MPS II; Hunter syndrome; OMIM 309900) is a rare, multisystemic, progressive lysosomal storage disease caused by deficient activity of the iduronate-2-sulfatase (I2S) enzyme. Accumulation of the glycosaminoglycans dermatan sulfate and heparan sulfate results in a broad range of disease manifestations that are highly variable in presentation and severity; notably, approximately two-thirds of individuals are affected by progressive central nervous system involvement. Historically, management of this disease was palliative; however, during the 1990s, I2S was purified to homogeneity for the first time, leading to cloning of the corresponding gene and offering a means of addressing the underlying cause of MPS II using enzyme replacement therapy (ERT)...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28763681/association-between-home-visit-nursing-utilization-and-all-cause-hospitalization-among-long-term-care-insurance-beneficiaries-a-retrospective-cohort-study
#10
Yeong Jun Ju, Hyo Jung Lee, Woorim Kim, Sang Ah Lee, Kyu-Tae Han, Eun-Cheol Park
BACKGROUND: Ensuring and improving long-term care services that use limited healthcare resources more efficiently is a major concern for many aging societies. OBJECTIVES: The aim of this study was to investigate the relationship between use of home-visit nursing services and all-cause hospitalization in a home-visit nursing-recommended group. DESIGN: A retrospective cohort study. SETTING: Population-based sample of long-term care insurance beneficiaries from the long-term care insurance 2002-2013 claims database in South Korea...
July 25, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28515183/modeling-lifetime-costs-and-health-outcomes-attributable-to-secondhand-smoke-exposure-at-home-among-korean-adult-women
#11
Jiyae Lee, Ah Ram Han, Dalwoong Choi, Kyung-Min Lim, SeungJin Bae
PURPOSE: The aim of this research is to estimate lifetime costs and health consequences for Korean adult women who were exposed to secondhand smoke (SHS) at home. METHODS: A Markov model was developed to project the lifetime healthcare costs and health outcomes of a hypothetical cohort of Korean women who are 40 years old and were married to current smokers. The Korean epidemiological data were used to reflect the natural history of SHS-exposed and non-exposed women...
May 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28455587/comprehensive-analysis-of-fungal-diversity-and-enzyme-activity-in-nuruk-a-korean-fermenting-starter-for-acquiring-useful-fungi
#12
Emily Carroll, Tran Ngoc Trinh, Hokyoung Son, Yin-Won Lee, Jeong-Ah Seo
Nuruk is a fermenting starter that is involved in the production of alcoholic beverages, and has been used in South Korea for a very long time. To analyze the fungal diversity, we collected a total of 59 nuruk samples from several companies and persons in 2013 to 2014, and obtained 364 isolates. All of the single isolated fungi were identified, both morphologically and molecularly, based on the sequences of ribosomal RNA gene [18S, ITS1-5.8S-ITS2, and 26S (D1/D2 region)]. In 46 nuruk samples out of 59 (78%), Saccharomycopsis fibuligera, a dimorphic yeast, was most frequently isolated...
May 2017: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/28414205/molecular-tumor-targeting-of-gelonin-by-fusion-with-f3-peptide
#13
Song-Hee Ham, Kyoung Ah Min, Meong Cheol Shin
Therapeutically potent macromolecular drugs have shown great promise for overcoming the limitations of small-molecule anti-cancer drugs. But tumor cell-selective intracellular delivery of the macromolecules remains a major hurdle for their successful clinical application. To overcome this challenge, we engineered a novel genetic fusion protein (F3-Gel) that composed of F3 peptide, a tumor-homing peptide, and gelonin, a plant-derived ribosome-inactivating protein (RIP), and then evaluated its anti-cancer activity in vitro and in vivo...
June 2017: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/28386386/prevalence-and-determinants-of-sufficient-fruit-and-vegetable-consumption-among-primary-school-children-in-nakhon-pathom-thailand
#14
Seo Ah Hong, Noppawan Piaseu
BACKGROUND/OBJECTIVES: Low consumption of fruit and vegetable is frequently viewed as an important contributor to obesity risk. With increasing childhood obesity and relatively low fruit and vegetable consumption among Thai children, there is a need to identify the determinants of the intake to promote fruit and vegetable consumption effectively. SUBJECTS/METHODS: This cross-sectional study was conducted at two conveniently selected primary schools in Nakhon Pathom...
April 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/28359823/tandem-multimeric-f3-gelonin-fusion-toxins-for-enhanced-anti-cancer-activity-for-prostate-cancer-treatment
#15
Meong Cheol Shin, Kyoung Ah Min, Heesun Cheong, Cheol Moon, Yongzhuo Huang, Huining He, Victor C Yang
Despite significant progress in prostate cancer treatment, yet, it remains the leading diagnosed cancer and is responsible for high incidence of cancer related deaths in the U.S. Because of the insufficient efficacy of small molecule anti-cancer drugs, significant interest has been drawn to more potent macromolecular agents such as gelonin, a plant-derived ribosome inactivating protein (RIP) that efficiently inhibits protein translation. However, in spite of the great potency to kill tumor cells, gelonin lacks ability to internalize tumor cells and furthermore, cannot distinguish between tumor and normal cells...
May 30, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28253389/technique-and-preliminary-analysis-of-drug-induced-sleep-endoscopy-with-online-polygraphic-cardiorespiratory-monitoring-in-patients-with-obstructive-sleep-apnea-syndrome
#16
Riccardo Gobbi, Simone Baiardi, Susanna Mondini, Luca Cerritelli, Ottavio Piccin, Giuseppe Scaramuzzino, Francesca Milano, Maria Rita Melotti, Francesco Mordini, Antonio Pirodda, Fabio Cirignotta, Giovanni Sorrenti
Importance: Drug-induced sleep endoscopy is a diagnostic technique that allows dynamic evaluation of the upper airway during artificial sleep. The lack of a standardized procedure and the difficulties associated with direct visual detection of obstructive events result in poor intraobserver and interobserver reliability, especially when otolaryngology surgeons not experienced in the technique are involved. Objectives: To describe a drug-induced sleep endoscopy technique implemented with simultaneous polygraphic monitoring of cardiorespiratory parameters (DISE-PG) in patients with a diagnosis of obstructive sleep apnea syndrome and discuss the technique's possible advantages compared with the standard procedure...
May 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28110007/human-health-and-ecological-assessment-programs-for-hebei-spirit-oil-spill-accident-of-2007-status-lessons-and-future-challenges
#17
Dawoon Jung, Jung-Ah Kim, Myung-Sook Park, Un Hyuk Yim, Kyungho Choi
Hebei Spirit oil spill (HSOS) of December 2007 is one of the worst oil spill accidents that occurred in Yellow Sea. The affected coastline along the west coast of Korean Peninsula hosts one of the largest tidal flats worldwide, and is home to tens of thousands of human residents. Based on nation-wide concerns on ecosystem damages and adverse human health effects, two separate surveillance programs on ecosystem and human health were initiated: a 10-year follow-up program by Ministry of Oceans and Fisheries to assess ecological impacts of the oil spill, and an exposure and health effect assessment program by Ministry of Environment for the residents of Taean and its vicinity...
April 2017: Chemosphere
https://www.readbyqxmd.com/read/28081241/cd25-cd127-foxp3-cells-represent-a-major-subpopulation-of-cd8-t-cells-in-the-eye-chambers-of-normal-mice
#18
Tomasz Maślanka, Natalia Ziółkowska, Hubert Ziółkowski, Joanna Małaczewska
The aim of this study has been to determine whether eye chambers constitute part of the normal migratory pathway of naive CD4+ and CD8+ T cells in mouse and if natural CD4+CD25+Foxp3+ and CD8+CD25+Foxp3+ regulatory T cells are present within these eye compartments. To this aim, the cells obtained from aqueous humor (AH) of normal mice were phenotyped in terms of the expression CD4, CD8, CD25, CD127 and transcription factor Foxp3. The mean percentage of CD8+ T cells in the total AH lymphocyte population was as high as 28...
2017: PloS One
https://www.readbyqxmd.com/read/27929757/predisposing-enabling-and-need-factors-associated-with-utilization-of-institutional-delivery-services-a-community-based-cross-sectional-study-in-far-western-nepal
#19
Leila Freidoony, Chhabi Lal Ranabhat, Chun-Bae Kim, Chang-Soo Kim, Dong-Won Ahn, Young Ah Doh
Use of institutional delivery services can be effective in reducing maternal and infant mortality. In Nepal, however, the majority of women deliver at home. Using Andersen's behavioral model of use of health care services, this cross-sectional study aimed to identify factors associated with use of institutional delivery services in four villages and one municipality in Kailali district, Nepal. Mothers (N = 500) who had given birth in the 5 years preceding the survey (conducted between January and February 2015) were randomly selected by cluster sampling and interviewed using a semi-structured questionnaire...
January 2018: Women & Health
https://www.readbyqxmd.com/read/27812622/inflammatory-response-of-human-dental-pulp-to-at-home-and-in-office-tooth-bleaching
#20
Maysa Magalhães Vaz, Lawrence Gonzaga Lopes, Paula Carvalho Cardoso, João Batista de Souza, Aline Carvalho Batista, Nádia Lago Costa, Érica Miranda Torres, Carlos Estrela
Objective: This study evaluated the inflammatory responses of human dental pulp after the use of two bleaching techniques. Material and Methods: Pulp samples were collected from human third molars extracted for orthodontic reasons and divided into three groups: control - no tooth bleaching (CG) (n=7); at-home bleaching with 15% carbamide peroxide (AH) (n = 10), and in-office bleaching with 38% hydrogen peroxide (IO) (n=12). Pulps were removed and stained with hematoxylin-eosin for microscopic analysis of inflammation intensity, collagen degradation, and pulp tissue organization...
September 2016: Journal of Applied Oral Science: Revista FOB
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