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Arterial hypertension nephritis

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https://www.readbyqxmd.com/read/29135152/-masks-of-urogenital-tuberculosis-as-the-cause-of-diagnostic-errors
#1
D P Kholtobin, E V Kulchavenya
Urogenital tuberculosis does not have pathognomonic symptoms, so diagnostic errors are quite common. This systematic review of literature was conducted to identify the causes and estimate the incidence of erroneous diagnoses. We critically evaluated some articles in which the authors describe observations of urogenital tuberculosis as rare and unusual because they never encountered this disease, but in fact that were typical manifestations of genitourinary tuberculosis. The authors analyzed and illustrated the features of urinary tuberculosis in patients with pulmonary tuberculosis, differential diagnosis of urogenital tuberculosis and kidney cancer and male genitourinary organs, described errors in the diagnosis of urethral, testicular, penile, prostatic and epididymal tuberculosis...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29042869/clinical-characteristics-of-hypertensive-encephalopathy-in-pediatric-patients
#2
Chang Hoon Ahn, Seung-A Han, Young Hwa Kong, Sun Jun Kim
PURPOSE: The aim of this study was to assess the clinical characteristics of hypertensive encephalopathy according to the underlying etiologies in children. METHODS: We retrospectively evaluated 33 pediatric patients who were diagnosed as having hypertensive encephalopathy in Chonbuk National University Children's Hospital. Among the patients, 18 were excluded because of incomplete data or because brain magnetic resonance imaging (MRI) was not performed. Finally, 17 patients were enrolled and divided into a renal-origin hypertension group and a non-renal-origin hypertension group according to the underlying cause...
August 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/28926602/autoimmune-disease-mouse-model-exhibits-pulmonary-arterial-hypertension
#3
Koichi Sugimoto, Kazuhiko Nakazato, Akihiko Sato, Satoshi Suzuki, Akiomi Yoshihisa, Takeshi Machida, Shu-Ichi Saitoh, Hideharu Sekine, Yasuchika Takeishi
BACKGROUND: Pulmonary arterial hypertension is often associated with connective tissue disease. Although there are some animal models of pulmonary hypertension, an autoimmune disease-based model has not yet been reported. MRL/lpr mice, which have hypergammaglobulinemia, produce various autoimmune antibodies, and develop vasculitis and nephritis spontaneously. However, little is known about pulmonary circulation in these mice. In the present study, we examined the pulmonary arterial pressure in MRL/lpr mice...
2017: PloS One
https://www.readbyqxmd.com/read/28884028/spontaneous-coronary-artery-dissection-a-rare-manifestation-of-alport-syndrome
#4
Amornpol Anuwatworn, Prince Sethi, Kelly Steffen, Orvar Jonsson, Marian Petrasko
Alport syndrome (AS) is a genetic disorder due to inheritance of genetic mutations which lead to production of abnormal type IV collagen. AS has been associated with renal, auditory, and ocular diseases due to the presence of abnormal alpha chains of type IV collagen in the glomerulus, cochlea, cornea, lens, and retina. The resulting disorder includes hereditary nephritis, corneal opacities, anterior lenticonus, fleck retinopathy, temporal retinal thinning, and sensorineural deafness. Aortic and aortic valve pathologies have been described as extrarenal manifestations of AS in multiple case reports...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28647487/does-pregnancy-have-any-impact-on-long-term-damage-accrual-and-on-the-outcome-of-lupus-nephritis
#5
Davide Gianfreda, Silvana Quaglini, Giulia Frontini, Francesca Raffiotta, Piergiorgio Messa, Gabriella Moroni
No data are available about the impact of pregnancy on the long-term outcome of lupus nephritis. Thirty-two women with lupus nephritis with a 10-year follow-up after their first pregnancy ("women who gave birth") and 64 matched controls with the same follow-up and who never had pregnancies ("controls") were compared for the occurrence of SLE flares, chronic kidney disease (CKD), and SLICC/ACR Damage Index (SDI) in the post pregnancy period. The same evaluations were done before and after pregnancy in women who gave birth...
November 2017: Journal of Autoimmunity
https://www.readbyqxmd.com/read/28053538/inverse-relationship-of-cardioankle-vascular-index-with-bmi-in-healthy-japanese-subjects-a-cross-sectional-study
#6
Daiji Nagayama, Haruki Imamura, Yuta Sato, Takashi Yamaguchi, Noriko Ban, Hidetoshi Kawana, Masahiro Ohira, Atsuhito Saiki, Kohji Shirai, Ichiro Tatsuno
OBJECTIVE: The objective of this study is to investigate the association of body mass index (BMI) with arterial stiffness assessed by cardioankle vascular index (CAVI). SUBJECTS AND METHODS: A retrospective cross-sectional study was conducted in 23,257 healthy Japanese subjects (12,729 men and 10,528 women, aged 47.1 ± 12.5 years, BMI 22.9 ± 3.4 kg/m(2)) who underwent health screening between 2004 and 2006 in Japan. Exclusion criteria were current medication use and a past history of cardiovascular disease, hypertension, stroke, diabetes, and nephritis...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/27753965/os-10-04-inverse-relationship-between-cardio-ankle-vascular-index-cavi-and-body-mass-index-in-healthy-japanese-subjects-a-cross-sectional-study
#7
Daiji Nagayama, Rena Watanabe, Yasuhiro Watanabe, Haruki Imamura, Yuta Sato, Takashi Yamaguchi, Noriko Ban, Hidetoshi Kawana, Masahiro Ohira, Atsuhito Saiki, Kohji Shirai, Ichiro Tatsuno
OBJECTIVE: To investigate the association of body mass index (BMI) with cardio-ankle vascular index (CAVI). DESIGN AND METHOD: We analyzed cross-sectional data from 23,257 healthy Japanese subjects (12,729 males and 10528 females) without past history of heart disease, hypertension, stroke, diabetes and nephritis between 20 and 74 (47.1 ± 12.5) years of age who underwent health screening during 2004 to 2006 in Japan. RESULTS: Male showed markedly higher BMI, CAVI, TG and lower HDL-C...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27673681/acute-kidney-injury-treated-with-dialysis-outside-the-intensive-care-unit-a-retrospective-observational-single-center-study
#8
Hannelore Sprenger-Mähr, Emanuel Zitt, Karl Lhotta
INTRODUCTION: The number of patients suffering from acute kidney injury requiring dialysis (AKI-D) is increasing. Whereas causes and outcome of AKI-D in the intensive care unit (ICU) are described extensively, few data exist about AKI-D patients treated outside the ICU. Aim of this study was to identify the causes of AKI-D, determine in-depth the comorbid conditions and outcome of this particular patient group and identify possibilities for its prevention. METHODS: We retrospectively studied all AKI-D patients treated outside the ICU in a single nephrology referral center between January 2010 and June 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27643362/os-10-04-inverse-relationship-between-cardio-ankle-vascular-index-cavi-and-body-mass-index-in-healthy-japanese-subjects-a-cross-sectional-study
#9
Daiji Nagayama, Rena Watanabe, Yasuhiro Watanabe, Haruki Imamura, Yuta Sato, Takashi Yamaguchi, Noriko Ban, Hidetoshi Kawana, Masahiro Ohira, Atsuhito Saiki, Kohji Shirai, Ichiro Tatsuno
OBJECTIVE: To investigate the association of body mass index (BMI) with cardio-ankle vascular index (CAVI). DESIGN AND METHOD: We analyzed cross-sectional data from 23,257 healthy Japanese subjects (12,729 males and 10528 females) without past history of heart disease, hypertension, stroke, diabetes and nephritis between 20 and 74 (47.1 ± 12.5) years of age who underwent health screening during 2004 to 2006 in Japan. RESULTS: Male showed markedly higher BMI, CAVI, TG and lower HDL-C...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27496151/fetal-outcome-and-recommendations-of-pregnancies-in-lupus-nephritis-in-the-21st-century-a-prospective-multicenter-study
#10
Gabriella Moroni, Andrea Doria, Elisa Giglio, Chiara Tani, Margherita Zen, Francesca Strigini, Barbara Zaina, Angela Tincani, Federica de Liso, Caterina Matinato, Claudia Grossi, Mariele Gatto, Paola Castellana, Monica Limardo, Pier Luigi Meroni, Piergiorgio Messa, Pietro Ravani, Marta Mosca
The aim of this multicenter study was to assess the present risk of fetal complications and the inherent risk factors in pregnant women with lupus nephritis. Seventy-one pregnancies in 61women (59 Caucasians and 2 Asians) with lupus nephritis were prospectively followed between October 2006 and December 2013. All patients received a counselling visit within 3 months before the beginning of pregnancy and were followed by a multidisciplinary team. At baseline mild active nephritis was present in 15 cases (21...
November 2016: Journal of Autoimmunity
https://www.readbyqxmd.com/read/27373903/maternal-outcome-in-pregnant-women-with-lupus-nephritis-a-prospective-multicenter-study
#11
Gabriella Moroni, Andrea Doria, Elisa Giglio, Enrico Imbasciati, Chiara Tani, Margherita Zen, Francesca Strigini, Barbara Zaina, Angela Tincani, Mariele Gatto, Federica de Liso, Claudia Grossi, Pier Luigi Meroni, Gianfranca Cabiddu, Piergiorgio Messa, Pietro Ravani, Marta Mosca
Retrospective studies reported a high incidence of maternal complications in pregnant women with lupus. In this paper we prospectively assessed the rate of risk and the risk factors of maternal outcome in women with stable lupus nephritis who received pre-pregnancy counseling. This prospective multicenter study includes 71 pregnancies in 61 women with lupus nephritis who became pregnant between 2006 and 2013. Complete renal remission was present before pregnancy in 56 cases (78.9%) and mild active nephritis in 15 cases...
November 2016: Journal of Autoimmunity
https://www.readbyqxmd.com/read/27009025/incidence-and-clinical-features-of-paediatric-vasculitis-in-eastern-china-14-year-retrospective-study-1999-2013
#12
Youying Mao, Lei Yin, Hui Xia, Hua Huang, Zhengyu Zhou, Tongxin Chen, Wei Zhou
OBJECTIVES: To determine the incidence and clinical features of paediatric primary vasculitis in patients from one centre in Eastern China. METHODS: Medical records of paediatric patients diagnosed with primary vasculitis between January 1999 and December 2013 were retrospectively reviewed. For Henoch-Schönlein purpura (HSP) and Kawasaki disease (KD), patients included in the analyses had data available for the previous 5 years. RESULTS: In total, 1896 patients were identified, of whom 1100 had HSP, 760 had KD, 23 had Takayasu arteritis, five had polyarteritis nodosa, four had cutaneous polyarteritis, three had Behçet's disease and one had microscopic polyangiitis...
June 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/26866934/does-renin-angiotensin-system-blockade-protect-lupus-nephritis-patients-from-atherosclerotic-cardiovascular-events-a-case-control-study
#13
Konstantinos Tselios, Dafna D Gladman, Jiandong Su, Murray B Urowitz
OBJECTIVE: Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are used as an adjuvant treatment in lupus nephritis (LN) patients with proteinuria. The primary aim of this study was to discover whether ACE inhibitors/ARBs have an atheroprotective effect similar to other, at-risk, populations. METHODS: A total of 144 patients (cases; mean ± SD age at onset 34 ± 12.1 years, followup 14.9 ± 8.6 years) with LN who were treated with ACE inhibitors/ARBs for at least 5 years were enrolled...
October 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/26827441/-role-of-biomarkers-in-estimation-of-renal-tubulointerstitial-tissue-damage-in-patients-with-chronic-glomerulonephritis
#14
O V Kraydaschenko, A V Abramov, M A Dolinnaya
AIM: to investigate the relationship between the levels of NGAL and IL-18 in.blood, urine and clinical, morphological parameters reflecting renal tubulointerstitial tissue damage (TTD) in patients with chronic glomerulonephritis (CGN). MATERIALS AND METHODS: We examined 81 patients with CGN. Patients were divided into 2 groups according to the presence of arterial hypertension (AH). Levels of NGAL and IL-18 in blood and urine were determined by the immuno-enzymic method...
April 2015: Likars'ka Sprava
https://www.readbyqxmd.com/read/26762471/chinese-sle-treatment-and-research-group-cstar-registry-vii-prevalence-and-clinical-significance-of-serositis-in-chinese-patients-with-systemic-lupus-erythematosus
#15
MULTICENTER STUDY
J Zhao, W Bai, P Zhu, X Zhang, S Liu, L Wu, L Ma, L Bi, X Zuo, L Sun, C Huang, X Tian, M Li, Y Zhao, X Zeng
OBJECTIVES: To investigate both the prevalence and clinical characteristics of serositis in Chinese patients with systemic lupus erythematosus (SLE) in a large cohort in the Chinese SLE Treatment and Research group (CSTAR) database. METHODS: A prospective cross-sectional study of patients with SLE was conducted based on the data from the CSTAR registry. Serositis was defined according to the 1999 revised American College of Rheumatology (ACR) criteria for SLE - that is, pleuritis/pleural effusion and/or pericarditis/pericardial effusion detected by echocardiography, chest X-ray or chest computerized tomography (CT) scan...
May 2016: Lupus
https://www.readbyqxmd.com/read/26574625/atorvastatin-reduced-soluble-receptors-of-tnf-alpha-in-systemic-lupus-erythematosus
#16
Gilda Aparecida Ferreira, Antonio Lúcio Teixeira, Debora Cerqueira Calderaro, Emília Inoue Sato
OBJECTIVES: The aim of this study was to evaluate the efficacy of atorvastatin to reduce the plasma levels of TNF system molecules (TNF-α, sTNFR1 and sTNFR2) and to assess their association with risk factors for accelerate atherosclerosis and clinical disease activity scores in SLE patients. METHODS: In a previous study, 64 female SLE patients received 20 mg/day of atorvastatin and 24 SLE patients (non-treated group) were followed for 8 weeks. Plasma levels of TNF-α, sTNFR 1 and sTNFR 2 were measured by ELISA, at baseline and at the end of the study...
January 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/26418213/pancreatitis-subtypes-survey-in-852-childhood-onset-systemic-lupus-erythematosus-patients
#17
MULTICENTER STUDY
Victor L S Marques, Natali W S Gormezano, Eloisa Bonfá, Nadia E Aikawa, Maria T Terreri, Rosa M Pereira, Claudia S Magalhães, Andressa Guariento, Simone Appenzeller, Virgínia P Ferriani, Cássia M Barbosa, Valéria C Ramos, Simone Lotufo, Clovis A Silva
OBJECTIVE: Pancreatitis is a rare and a life-threatening systemic lupus erythematosus (SLE) manifestation in childhood-onset SLE (cSLE). The objective of this study was to systematically classify pancreatitis in cSLE according to the International Study Group of Pediatric Pancreatitis and determine the overall prevalence, clinical features, laboratory, and first episode outcomes. METHODS: A multicenter cohort study in 10 pediatric rheumatology centers, including 852 patients with cSLE...
February 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/26350991/lamotrigine-induced-tubulointerstitial-nephritis-and-uveitis-atypical-cogan-syndrome
#18
Anton M Kolomeyer, Shyam Kodati
PURPOSE: To report a case of lamotrigine-induced tubulointerstitial nephritis and uveitis (TINU)-atypical Cogan syndrome. METHODS: Case report. RESULTS: A 16-year-old boy with traumatic brain injury and seizures presented to the emergency department with facial swelling, rash, and back pain several days after increasing lamotrigine dose secondary to a breakthrough seizure. Creatinine, urine β2 microglobulin, and eosinophils were elevated...
January 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/26281189/-role-of-the-morphogenetic-proteins-fgf-23-and-klotho-and-the-glycoprotein-sclerostin-in-the-assessment-of-the-risk-of-cardiovascular-diseases-and-the-prognosis-of-chronic-kidney-disease
#19
L Yu Milovanova, Yu S Milovanov, D V Kudryavtseva, M M Markina, S Yu Milovanova, L V Kozlovskaya, M V Lebedeva, V D Beketov, S V Moiseev, N A Mukhin, V V Fomin, A A Svistunov
UNLABELLED: AIM. To analyze changes in the serum concentrations of the morphogenetic proteins fibroblast growth factor 23 (FGF-23) and Klotho, as well as sclerostin, an osteocyte-secreted glycoprotein, in relation to the degree of hypertension, left ventricular (LV) hypertrophy, and arterial stiffness in patients with chronic kidney disease (CKD) at its different stages. SUBJECTS AND METHODS: Sixty-five patients (33 men and 32 women) aged 20-65 years, including 25 with chronic glomerulonephritis, 15 with tubulointerstitial nephritis, and 25 with hypertensive nephrosclerosis, were examined...
2015: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/25894566/nephrotic-syndrome-and-thrombotic-microangiopathy-caused-by-cobalamin-c-deficiency
#20
Jens C Koenig, Frank Rutsch, Clemens Bockmeyer, Matthias Baumgartner, Bodo B Beck, Brigitta Kranz, Martin Konrad
BACKGROUND: Cobalamin C (CblC) defects are inherited autosomal recessive disorders of vitamin B12 metabolism due to mutations in the MMACHC gene. Renal manifestations include thrombotic microangiopathy (TMA), acute or chronic renal failure, tubulointerstitial nephritis, and proximal renal tubular acidosis. However, reports about glomerular pathologies are scarce. CASE REPORT: A 4-year-old boy presented with nephrotic syndrome, arterial hypertension, and chronic anemia but no signs of hemolysis...
July 2015: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
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