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https://www.readbyqxmd.com/read/29691930/through-focus-optical-characteristics-of-monofocal-and-bifocal-soft-contact-lenses-across-the-peripheral-visual-field
#1
Qiuzhi Ji, Young-Sik Yoo, Hira Alam, Geunyoung Yoon
PURPOSE: To characterise the impact of monofocal soft contact lens (SCL) and bifocal SCLs on refractive error, depth of focus (DoF) and orientation of blur in the peripheral visual field. METHODS: Monofocal and two bifocal SCLs, Acuvue Bifocal (AVB, Johnson & Johnson) and Misight Dual Focus (DF, CooperVision) with +2.0 D add power were modelled using a ray tracing program (ZEMAX) based on their power maps. These SCLs were placed onto the anterior corneal surface of the simulated Atchison myopic eye model to correct for -3...
May 2018: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/29689753/development-and-application-of-computer-assisted-optimal-method-for-treatment-of-femoral-neck-fracture
#2
Monan Wang, Kai Zhang, Ning Yang
BACKGROUND: To help doctors decide their treatment from the aspect of mechanical analysis, the work built a computer assisted optimal system for treatment of femoral neck fracture oriented to clinical application. OBJECTIVE: The whole system encompassed the following three parts: Preprocessing module, finite element mechanical analysis module, post processing module. METHODS: Preprocessing module included parametric modeling of bone, parametric modeling of fracture face, parametric modeling of fixed screw and fixed position and input and transmission of model parameters...
April 9, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29689170/curriculum-based-handwriting-programs-a-systematic-review-with-effect-sizes
#3
Courtney Engel, Kristin Lillie, Sarah Zurawski, Brittany G Travers
Challenges with handwriting can have a negative impact on academic performance, and these challenges are commonly addressed by occupational therapy practitioners in school settings. This systematic review examined the efficacy of curriculum-based interventions to address children's handwriting difficulties in the classroom (preschool to second grade). We reviewed and computed effect sizes for 13 studies (11 Level II, 2 Level III) identified through a comprehensive database search. The evidence shows that curriculum-based handwriting interventions resulted in small- to medium-sized improvements in legibility, a commonly reported challenge in this age group...
May 2018: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/29688108/a-novel-workplace-based-assessment-for-competency-based-decisions-and-learner-feedback
#4
Patricia J Hicks, Melissa J Margolis, Carol L Carraccio, Brian E Clauser, Kathleen Donnelly, H Barrett Fromme, Kimberly A Gifford, Sue E Poynter, Daniel J Schumacher, Alan Schwartz
BACKGROUND: Increased recognition of the importance of competency-based education and assessment has led to the need for practical and reliable methods to assess relevant skills in the workplace. METHODS: A novel milestone-based workplace assessment system was implemented in 15 pediatrics residency programs. The system provided: (1) web-based multisource feedback (MSF) and structured clinical observation (SCO) instruments that could be completed on any computer or mobile device; and (2) monthly feedback reports that included competency-level scores and recommendations for improvement...
April 24, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29688032/setting-up-an-epathology-service-at-cleveland-clinic-abu-dhabi-joint-collaboration-with-cleveland-clinic-united-states
#5
Ayoub Nahal, Crystal Mildred O Batac, Renee J Slaw, Thomas W Bauer
CONTEXT: - The production of whole slide images is the most advanced form of digital pathology, in which a high-resolution digital scanner is used to rapidly scan glass microscope slides and produce a computer-generated whole slide image that can be saved, stored in a network-attached storage device, and accessed through slide management software within the hospital domain and remotely by authorized users. Digital transformation of glass slides has revolutionized the practice of anatomic pathology by facilitating and expediting consultative services, improving clinical workflow, and becoming an indispensable tool in education and research...
April 24, 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29686474/impact-of-enhanced-recovery-after-surgery-programs-on-pancreatic-surgery-a-meta-analysis
#6
Hai-Bin Ji, Wen-Tao Zhu, Qiang Wei, Xiao-Xiao Wang, Hai-Bin Wang, Qiang-Pu Chen
AIM: To evaluate the impact of enhanced recovery after surgery (ERAS) programs on postoperative complications of pancreatic surgery. METHODS: Computer searches were performed in databases (including PubMed, Cochrane Library and Embase) for randomized controlled trials or case-control studies describing ERAS programs in patients undergoing pancreatic surgery published between January 1995 and August 2017. Two researchers independently evaluated the quality of the studies' extracted data that met the inclusion criteria and performed a meta-analysis using RevMan5...
April 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29686133/improving-long-term-adherence-to-statin-therapy-a-qualitative-study-of-gps-experiences-in-primary-care
#7
Karen Krüger, Niklas Leppkes, Sabine Gehrke-Beck, Wolfram Herrmann, Engi A Algharably, Reinhold Kreutz, Christoph Heintze, Iris Filler
BACKGROUND: Statins substantially reduce the risk of cardiovascular disease when taken regularly. Though statins are generally well tolerated, current studies show that one-third of patients discontinue use of statins within 2 years. A qualitative approach may improve the understanding of attitudes and behaviours towards statins, the mechanisms related to discontinuation, and how they are managed in primary care. AIM: To identify factors related to statin discontinuation and approaches for long-term statin adherence...
April 23, 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29685591/cardiovascular-event-reduction-with-pcsk9-inhibition-among-1578-patients-with-familial-hypercholesterolemia-results-from-the-spire-randomized-trials-of-bococizumab
#8
Paul M Ridker, Lynda M Rose, John J P Kastelein, Raul D Santos, Caimiao Wei, James Revkin, Carla Yunis, Jean-Claude Tardif, Charles L Shear
BACKGROUND: Familial hypercholesterolemia (FH) is a dominant genetic disorder associated with elevated low-density lipoprotein cholesterol (LDL-C) and premature atherosclerotic events. Although therapeutic monoclonal antibodies that inhibit proprotein convertase subtilisin-kexin type 9 (PCSK9) are indicated for LDL-C reduction among adult patients with FH, placebo-controlled outcome data among FH patients are scant. OBJECTIVE: Directly compare the efficacy of PCSK9 inhibition as compared to placebo on hard cardiovascular outcomes in FH patients enrolled in the Studies of PCSK9 Inhibition and the Reduction of vascular Events (SPIRE) program...
April 3, 2018: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29684782/evaluation-of-normal-lung-tissue-complication-probability-in-gated-and-conventional-radiotherapy-using-the-4d-xcat-digital-phantom
#9
Sara Shahzadeh, Somayeh Gholami, Seyed Mahmood Reza Aghamiri, Hojjat Mahani, Mansoure Nabavi, Faraz Kalantari
PURPOSE: The present study was conducted to investigate normal lung tissue complication probability in gated and conventional radiotherapy (RT) as a function of diaphragm motion, lesion size, and its location using 4D-XCAT digital phantom in a simulation study. MATERIALS AND METHODS: Different time series of 3D-CT images were generated using the 4D-XCAT digital phantom. The binary data obtained from this phantom were then converted to the digital imaging and communication in medicine (DICOM) format using an in-house MATLAB-based program to be compatible with our treatment planning system (TPS)...
April 12, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29682511/preferences-of-older-adults-and-their-families-for-meaningful-use-clinical-summaries
#10
Karen Colorafi, Robert A Greenes, Marc Kates
Background: This study assessed the perceptions of older adults regarding the plan of care (POC) contained in the clinical summary mandated by the Electronic Health Records (EHR) Incentive Program. Methods: A qualitative descriptive design was selected for this study. Older adults (≥65) with chronic cardiac diagnoses were invited to participate. The investigator shadowed the physician during the patient encounter, interviewed the patients following their encounter, and asked patients to complete standard health literacy and cognitive screening tools and the Patient Activation Measure...
2018: MHealth
https://www.readbyqxmd.com/read/29681931/development-of-a-physiological-frailty-index-for-the-world-trade-center-general-responder-cohort
#11
Ghalib A Bello, Roberto G Lucchini, Susan L Teitelbaum, Moshe Shapiro, Michael A Crane, Andrew C Todd
Responders to the 9/11/2001 WTC attacks were exposed to multiple toxic pollutants. Since 2002, the health of the responder cohort has been continuously tracked by the WTC Health Monitoring Program. However, no assessments have been made of frailty, an important health metric given the current average age of the WTC responder cohort (55 years). In this study, we use laboratory test results and other physiological parameters to construct a physiological frailty index (FI-Lab) for this cohort. The study sample comprised responders aged 40 years or older who completed a health monitoring visit at Mount Sinai Center within the past 5 years...
2018: Current Gerontology and Geriatrics Research
https://www.readbyqxmd.com/read/29681240/pembrolizumab-combined-with-stereotactic-body-radiotherapy-in-a-patient-with-human-immunodeficiency-virus-and-advanced-non-small-cell-lung-cancer-a-case-report
#12
Dongqi Li, Chuanchun He, Yaoxiong Xia, Yaxi Du, Jing Zhang
BACKGROUND: Pembrolizumab has significantly improved outcomes in patients with advanced non-small cell lung cancer. Combining programmed death-1 inhibitor with stereotactic body radiotherapy showed a slight toxicity and good benefits in recent clinical trials. However, patients infected with human immunodeficiency virus were excluded from most trials because it was assumed that their anti-tumor immunity was compromised compared with immunocompetent patients. CASE PRESENTATION: In June 2016, a 52-year-old Chinese man presented with human immunodeficiency virus and lung adenocarcinoma (T1bN3M1b)...
April 23, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29681170/perceptions-of-family-among-low-income-patients-with-diabetes-in-a-text-based-mobile-health-intervention
#13
Elizabeth R E Burner, Michael D Menchine, Katrina Kubicek, Marisela Robles, Marjorie Kagawa Singer, Sanjay Arora
BACKGROUND: Diabetes disproportionately affects the US Latino population, due to socioeconomic pressures, genetics, reduced access to care and cultural practices. While efforts to improve self-care through interventions incorporating family are highly rated by Latinos, family can be both supportive and obstructive. To develop effective interventions, this role needs clarification. METHODS: We conducted group interviews in Spanish and English with 24 participants with diabetes from a mobile health diabetes self-care intervention...
April 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29678199/megan-lr-new-algorithms-allow-accurate-binning-and-easy-interactive-exploration-of-metagenomic-long-reads-and-contigs
#14
Daniel H Huson, Benjamin Albrecht, Caner Bağcı, Irina Bessarab, Anna Górska, Dino Jolic, Rohan B H Williams
BACKGROUND: There are numerous computational tools for taxonomic or functional analysis of microbiome samples, optimized to run on hundreds of millions of short, high quality sequencing reads. Programs such as MEGAN allow the user to interactively navigate these large datasets. Long read sequencing technologies continue to improve and produce increasing numbers of longer reads (of varying lengths in the range of 10k-1M bps, say), but of low quality. There is an increasing interest in using long reads in microbiome sequencing, and there is a need to adapt short read tools to long read datasets...
April 20, 2018: Biology Direct
https://www.readbyqxmd.com/read/29677991/architecture-and-initial-development-of-a-knowledge-as-a-service-activator-for-computable-knowledge-objects-for-health
#15
Allen J Flynn, Peter Boisvert, Nate Gittlen, Colin Gross, Brad Iott, Carl Lagoze, George Meng, Charles P Friedman
The Knowledge Grid (KGrid) is a research and development program toward infrastructure capable of greatly decreasing latency between the publication of new biomedical knowledge and its widespread uptake into practice. KGrid comprises digital knowledge objects, an online Library to store them, and an Activator that uses them to provide Knowledge-as-a-Service (KaaS). KGrid's Activator enables computable biomedical knowledge, held in knowledge objects, to be rapidly deployed at Internet-scale in cloud computing environments for improved health...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677975/minimal-important-difference-in-outcome-of-disc-degenerative-disease-treatment-the-patients-perspective
#16
Linda Greta Dui, Federico Cabitza, Pedro Berjano
Evaluation of treatments effectiveness in a context of value-based health care is based on outcomes, and in their assessment. The patient perspective is gaining renovated interest, as demonstrated by the increasing diffusion of Patient Reported Outcome Measure (PROMs) collection initiatives. The concept of Minimal Clinically Important Dif-ference (MID) is generally seen as the basis to estimate the actual effect perceived by the patient after a treatment, like a surgical intervention, but a universally recognized threshold has not yet been established...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29675690/a-new-algorithm-to-build-bridges-between-two-patient-reported-health-outcome-instruments-the-mos-sf-36%C3%A2-and-the-vr-12-health-survey
#17
Alfredo Selim, William Rogers, Shirley Qian, James A Rothendler, Erin E Kent, Lewis E Kazis
PURPOSE: To develop bridging algorithms to score the Veterans Rand-12 (VR-12) scales for comparability to those of the SF-36® for facilitating multi-cohort studies using data from the National Cancer Institute Surveillance, Epidemiology, and End Results Program (SEER) linked to Medicare Health Outcomes Survey (MHOS), and to provide a model for minimizing non-statistical error in pooled analyses stemming from changes to survey instruments over time. METHODS: Observational study of MHOS cohorts 1-12 (1998-2011)...
April 19, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29672558/the-effects-of-unexpected-mechanical-perturbations-during-treadmill-walking-on-spatiotemporal-gait-parameters-and-the-dynamic-stability-measures-by-which-to-quantify-postural-response
#18
Forough Madehkhaksar, Jochen Klenk, Kim Sczuka, Katharina Gordt, Itshak Melzer, Michael Schwenk
Most falls occur after a loss of balance following an unexpected perturbation such as a slip or a trip. Greater understanding of how humans control and maintain stability during perturbed walking may help to develop appropriate fall prevention programs. The aim of this study was to examine changes in spatiotemporal gait and stability parameters in response to sudden mechanical perturbations in medio-lateral (ML) and anterior-posterior (AP) direction during treadmill walking. Moreover, we aimed to evaluate which parameters are most representative to quantify postural recovery responses...
2018: PloS One
https://www.readbyqxmd.com/read/29672427/using-computer-adaptive-quizzing-as-a-tool-for-national-council-licensure-examination-success
#19
Jill Pence, Felecia Wood
This study examined the relationship between using computer-adaptive quizzing (CAQ) and first-time National Council Licensure Examination (NCLEX) success. A retrospective, descriptive, correlational design was used to analyze the relationship between use of a CAQ program and first-time NCLEX results of 194 baccalaureate graduates. Chi-square analysis suggested that there was an association between using the software and NCLEX success (p < .001, df = 1), with 16 percent of those without access compared to 1 percent with access being unsuccessful on the licensure exam...
May 2018: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29672122/pruning-of-the-pulmonary-vasculature-in-asthma-the-sarp-cohort
#20
Samuel Y Ash, Farbod N Rahaghi, Carolyn E Come, James C Ross, Alysha G Colon, Juan Carlos Cardet-Guisasola, Eleanor M Dunican, Eugene R Bleecker, Mario Castro, John V Fahy, Sean B Fain, Benjamin M Gaston, Eric A Hoffman, Nizar N Jarjour, David T Mauger, Sally E Wenzel, Bruce D Levy, Raul San Jose Estepar, Elliot Israel, George R Washko
RATIONALE: Loss of the peripheral pulmonary vasculature, termed vascular pruning, is associated with disease severity in patients with chronic obstructive pulmonary disease. OBJECTIVES: To determine if pulmonary vascular pruning is associated with asthma severity and exacerbations. METHODS: We measured the total pulmonary blood vessel volume (TBV) and the blood vessel volume of vessels less than 5mm2 in cross sectional area (BV5) and of vessels less than 10mm2 (BV10) in cross sectional area on non-contrast computed tomographic scans of participants from the Severe Asthma Research Program...
April 19, 2018: American Journal of Respiratory and Critical Care Medicine
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