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closed-system transfer device

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https://www.readbyqxmd.com/read/29136298/tuning-the-f%C3%A3-rster-resonance-energy-transfer-through-self-assembly-approach-for-efficient-white-light-emission-in-aqueous-medium
#1
Pragyan Pallavi, Bahadur Sk, Palak Ahir, Abhijit Patra
A simple and cost-effective methodology employing environmentally benign substances for the fabrication of white-light emitting materials is important for practical applications in the field of lighting and display devices. Designing of purely organic-based white-light emitting system with high quantum efficiency in the aqueous medium is an unmet challenge. With this objective, a new class of pyridoindole based hydrophobic fluorophore 6,7,8,9-tetrapropylpyrido[1,2-a]indole-10-carbaldehye (TPIC) was introduced...
November 14, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29073136/a-bacterial-toxin-antitoxin-module-is-the-origin-of-inter-bacterial-and-inter-kingdom-effectors-of-bartonella
#2
Alexander Harms, Marius Liesch, Jonas Körner, Maxime Québatte, Philipp Engel, Christoph Dehio
Host-targeting type IV secretion systems (T4SS) evolved from conjugative T4SS machineries that mediate interbacterial plasmid transfer. However, the origins of effectors secreted by these virulence devices have remained largely elusive. Previous work showed that some effectors exhibit homology to toxins of bacterial toxin-antitoxin modules, but the evolutionary trajectories underlying these ties had not been resolved. We previously reported that FicT toxins of FicTA toxin-antitoxin modules disrupt cellular DNA topology via their enzymatic FIC (filamentation induced by cAMP) domain...
October 2017: PLoS Genetics
https://www.readbyqxmd.com/read/29061556/impact-of-an-electronic-monitoring-intervention-to-improve-adherence-to-inhaled-medication-in-patients-with-asthma-and-chronic-obstructive-pulmonary-disease-study-protocol-for-a-randomized-controlled-trial
#3
Claudia Gregoriano, Thomas Dieterle, Selina Dürr, Isabelle Arnet, Kurt E Hersberger, Jörg D Leuppi
BACKGROUND: Despite progress in pharmacological and non-pharmacological treatment in recent years, the burden of disease among patients with asthma and chronic obstructive pulmonary disease (COPD) is high and patients are frequently hospitalized due to exacerbations. Reasons for uncontrolled diseases are manifold, but are often associated with poor inhalation technique and non-adherence to the prescribed treatment plan. This causes substantial mortality, morbidity, and costs to the healthcare system...
October 23, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29041769/high-mechanical-bandwidth-fiber-coupled-fabry-perot-cavity
#4
Erika Janitz, Maximilian Ruf, Yannik Fontana, Jack Sankey, Lilian Childress
Fiber-based optical microcavities exhibit high quality factor and low mode volume resonances that make them attractive for coupling light to individual atoms or other microscopic systems. Moreover, their low mass should lead to excellent mechanical response up to high frequencies, opening the possibility for high bandwidth stabilization of the cavity length. Here, we demonstrate a locking bandwidth of 44 kHz achieved using a simple, compact design that exploits these properties. Owing to the simplicity of fiber feedthroughs and lack of free-space alignment, this design is inherently compatible with vacuum and cryogenic environments...
August 21, 2017: Optics Express
https://www.readbyqxmd.com/read/28981323/a-strategy-for-formulating-regulation-on-cstds
#5
Allison Field, Gemma Hughes, Sarah Rowland
This article identifies what steps need to be taken to ensure the mandatory use of closed system transfer devices by all health professionals involved in the hazardous drug journey.
September 6, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28981322/the-need-for-national-mandatory-guidance-on-cstds
#6
Elizabeth Meade, Alison Simons, Samantha Toland
Closed system transfer devices play a vital role in reducing health professionals' risk of exposure to hazardous drugs. Although recommended as a first line of defence against contamination, they are not widely used. Clear mandatory national guidance is needed to address this.
September 6, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28874560/ultrafast-fluorescent-decay-induced-by-metal-mediated-dipole-dipole-interaction-in-two-dimensional-molecular-aggregates
#7
Qing Hu, Dafei Jin, Jun Xiao, Sang Hoon Nam, Xiaoze Liu, Yongmin Liu, Xiang Zhang, Nicholas X Fang
Two-dimensional molecular aggregate (2DMA), a thin sheet of strongly interacting dipole molecules self-assembled at close distance on an ordered lattice, is a fascinating fluorescent material. It is distinctively different from the conventional (single or colloidal) dye molecules and quantum dots. In this paper, we verify that when a 2DMA is placed at a nanometric distance from a metallic substrate, the strong and coherent interaction between the dipoles inside the 2DMA dominates its fluorescent decay at a picosecond timescale...
September 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28855476/validation-of-simultaneous-analytical-method-of-veterinary-drugs-in-foods-using-new-automatic-pretreatment-equipment
#8
Yoichi Yatsukawa, Daisuke Kusuno, Takahiro Matsuda, Kazuhiro Kobayashi, Tetsuro Ohba
New automatic pretreatment equipment (FASVED; Food Automatic Analytical Systems for Veterinary Drugs) was developed. FASVED consists of ten main units: reagent dispenser, homogenizer, transfer hand, lid opening/closing device, centrifugal separator, pipette, shaker, column purification device, centrifugal evaporator and cooling device, and it is capable of freely combining operations by these units. A validation study was performed on two methods for determination of 178 veterinary drugs in livestock products, swine muscle, egg and shrimp, according to the method validation guideline of the Ministry of Health, Labour and Welfare of Japan...
2017: Shokuhin Eiseigaku Zasshi. Journal of the Food Hygienic Society of Japan
https://www.readbyqxmd.com/read/28841099/survey-of-guidelines-and-current-practices-for-safe-handling-of-antineoplastic-and-other-hazardous-drugs-used-in-24-countries
#9
Patricia I Mathias, Barbara A MacKenzie, Christine A Toennis, Thomas H Connor
Purpose A survey of guidelines and current practices was conducted to examine the safe handling procedures for antineoplastic and other hazardous drugs that are used in 24 countries including the Americas, Europe, the Mideast, Far East, and Australia. Methods Subject experts were asked to complete a brief survey regarding safe handling guidelines and practices for hazardous drugs in their countries. Questions addressed practices for handling monoclonal antibodies, the use of closed-system transfer devices, medical surveillance practices, and measurements of compliance with existing guidelines...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/28839127/multi-orbital-charge-transfer-at-highly-oriented-organic-metal-interfaces
#10
Giovanni Zamborlini, Daniel Lüftner, Zhijing Feng, Bernd Kollmann, Peter Puschnig, Carlo Dri, Mirko Panighel, Giovanni Di Santo, Andrea Goldoni, Giovanni Comelli, Matteo Jugovac, Vitaliy Feyer, Claus Michael Schneidery
The molecule-substrate interaction plays a key role in charge injection organic-based devices. Charge transfer at molecule-metal interfaces strongly affects the overall physical and magnetic properties of the system, and ultimately the device performance. Here, we report theoretical and experimental evidence of a pronounced charge transfer involving nickel tetraphenyl porphyrin molecules adsorbed on Cu(100). The exceptional charge transfer leads to filling of the higher unoccupied orbitals up to LUMO+3. As a consequence of this strong interaction with the substrate, the porphyrin's macrocycle sits very close to the surface, forcing the phenyl ligands to bend upwards...
August 25, 2017: Nature Communications
https://www.readbyqxmd.com/read/28750540/electrochromic-sensor-for-multiplex-detection-of-metabolites-enabled-by-closed-bipolar-electrode-coupling
#11
Wei Xu, Kaiyu Fu, Paul W Bohn
Biosensors based on converting electrochemical signals into optical readouts are attractive candidates as low-cost, high-throughput sensor platforms. Here, we described a closed bipolar electrode (CBE)-based two-cell electrochromic device for sensing multiple metabolites, using the simultaneous detection of lactate, glucose, and uric acid as a model system. In the two-cell configuration, an analytical cell contains a redox mediator combined with a specific oxidase, e.g., lactate oxidase, glucose oxidase, or uricase, to form an electrochemical mediator-electrocatalyst pair that supports redox cycling...
July 28, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28745439/a-double-stimuli-responsive-fluorescent-center-for-monitoring-of-food-spoilage-based-on-dye-covalently-modified-eumofs-from-sensory-hydrogels-to-logic-devices
#12
Xiao-Yu Xu, Xiao Lian, Ji-Na Hao, Chi Zhang, Bing Yan
Unsafe food is a huge threat to human health and the economy, and detecting food spoilage early is an ongoing and imperative need. Herein, a simple and effective strategy combining a fluorescence sensor and one-to-two logic operation is designed for monitoring biogenic amines, indicators of food spoilage. Sensors (methyl red@lanthanide metal-organic frameworks (MR@EuMOFs)) are created by covalently modifying MR into NH2 -rich EuMOFs, which have a high quantum yield (48%). A double-stimuli-responsive fluorescence center is produced via energy transfer from the ligands to Eu(3+) and MR...
July 26, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28714119/high-performance-polymers-sandwiched-with-chemical-vapor-deposited-hexagonal-boron-nitrides-as-scalable-high-temperature-dielectric-materials
#13
Amin Azizi, Matthew R Gadinski, Qi Li, Mohammed Abu AlSaud, Jianjun Wang, Yi Wang, Bo Wang, Feihua Liu, Long-Qing Chen, Nasim Alem, Qing Wang
Polymer dielectrics are the preferred materials of choice for power electronics and pulsed power applications. However, their relatively low operating temperatures significantly limit their uses in harsh-environment energy storage devices, e.g., automobile and aerospace power systems. Herein, hexagonal boron nitride (h-BN) films are prepared from chemical vapor deposition (CVD) and readily transferred onto polyetherimide (PEI) films. Greatly improved performance in terms of discharged energy density and charge-discharge efficiency is achieved in the PEI sandwiched with CVD-grown h-BN films at elevated temperatures when compared to neat PEI films and other high-temperature polymer and nanocomposite dielectrics...
July 17, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28541102/considering-closed-system-transfer-devices-for-safe-handling-of-drugs
#14
Elaine Lennan
No abstract text is available yet for this article.
May 25, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28507160/emergent-magnetism-at-transition-metal-nanocarbon-interfaces
#15
Fatma Al Ma'Mari, Matthew Rogers, Shoug Alghamdi, Timothy Moorsom, Stephen Lee, Thomas Prokscha, Hubertus Luetkens, Manuel Valvidares, Gilberto Teobaldi, Machiel Flokstra, Rhea Stewart, Pierluigi Gargiani, Mannan Ali, Gavin Burnell, B J Hickey, Oscar Cespedes
Charge transfer at metallo-molecular interfaces may be used to design multifunctional hybrids with an emergent magnetization that may offer an eco-friendly and tunable alternative to conventional magnets and devices. Here, we investigate the origin of the magnetism arising at these interfaces by using different techniques to probe 3d and 5d metal films such as Sc, Mn, Cu, and Pt in contact with fullerenes and rf-sputtered carbon layers. These systems exhibit small anisotropy and coercivity together with a high Curie point...
May 30, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28410594/physical-human-robot-interaction-of-an-active-pelvis-orthosis-toward-ergonomic-assessment-of-wearable-robots
#16
Nicolò d'Elia, Federica Vanetti, Marco Cempini, Guido Pasquini, Andrea Parri, Marco Rabuffetti, Maurizio Ferrarin, Raffaele Molino Lova, Nicola Vitiello
BACKGROUND: In human-centered robotics, exoskeletons are becoming relevant for addressing needs in the healthcare and industrial domains. Owing to their close interaction with the user, the safety and ergonomics of these systems are critical design features that require systematic evaluation methodologies. Proper transfer of mechanical power requires optimal tuning of the kinematic coupling between the robotic and anatomical joint rotation axes. We present the methods and results of an experimental evaluation of the physical interaction with an active pelvis orthosis (APO)...
April 14, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28332444/a-functional-electrical-stimulation-system-for-human-walking-inspired-by-reflexive-control-principles
#17
Lin Meng, Bernd Porr, Catherine A Macleod, Henrik Gollee
This study presents an innovative multichannel functional electrical stimulation gait-assist system which employs a well-established purely reflexive control algorithm, previously tested in a series of bipedal walking robots. In these robots, ground contact information was used to activate motors in the legs, generating a gait cycle similar to that of humans. Rather than developing a sophisticated closed-loop functional electrical stimulation control strategy for stepping, we have instead utilised our simple reflexive model where muscle activation is induced through transfer functions which translate sensory signals, predominantly ground contact information, into motor actions...
April 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28315750/fun-cube-based-brain-gym-cognitive-function-assessment-system
#18
Tao Zhang, Chung-Chih Lin, Tsang-Chu Yu, Jing Sun, Wen-Chuin Hsu, Alice May-Kuen Wong
The aim of this study is to design and develop a fun cube (FC) based brain gym (BG) cognitive function assessment system using the wireless sensor network and multimedia technologies. The system comprised (1) interaction devices, FCs and a workstation used as interactive tools for collecting and transferring data to the server, (2) a BG information management system responsible for managing the cognitive games and storing test results, and (3) a feedback system used for conducting the analysis of cognitive functions to assist caregivers in screening high risk groups with mild cognitive impairment...
March 3, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28315550/hazardous-drugs-and-usp-800-implications-for-nurses
#19
Seth Eisenberg
BACKGROUND: Although guidelines for the safe handling of hazardous drugs (HDs) have existed for several decades, they have not been enforceable by state or federal agencies. USP <800>, the latest chapter issued by the U.S. Pharmacopeial Convention, expands on existing guidelines and provides detailed information on compounding and administration. Unlike current guidelines, USP <800> will be enforced by each state's board of pharmacy or their delegated agency.
. OBJECTIVES: This article provides a brief overview of the dangers associated with HDs and the implications of USP <800> for nurses...
April 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28268953/on-the-capacity-of-diffusion-based-molecular-communications-with-sinw-fet-based-receiver
#20
Murat Kuscu, Ozgur B Akan
Molecular communication (MC) is a bio-inspired communication method based on the exchange of molecules for information transfer among nanoscale devices. Although MC has been extensively studied from various aspects, limitations imposed by the physical design of transceiving units have been largely neglected in the literature. Recently, we have proposed a nanobioelectronic MC receiver architecture based on the nanoscale field effect transistor-based biosensor (bioFET) technology, providing noninvasive and sensitive molecular detection at nanoscale while producing electrical signals at the output...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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