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https://www.readbyqxmd.com/read/28858962/drug-induced-myopia-and-bilateral-angle-closure-secondary-to-zolmitriptan
#1
Jonathan Tak Loong Lee, Simon Edward Skalicky, Ming-Lee Lin
PURPOSE: To describe a unique case of drug-induced transient myopia with angle-closure glaucoma in a patient being treated with zolmitriptan for migraines. METHODS: A 42-year-old woman who had been using increasing amounts of zolmitriptan over the previous 12 months presented with an acute myopic shift and raised intraocular pressures (IOP) with anterior chamber shallowing. Clinical examination findings at presentation and at follow-up visits were reviewed. RESULTS: Initial examination revealed unaided visual acuities of 20/100 in the right eye and 20/125 in the left, with IOP measuring 34 mm Hg bilaterally...
August 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28815087/ocular-and-systemic-risk-factors-of-different-morphologies-of-scotoma-in-patients-with-normal-tension-glaucoma
#2
Ewa Kosior-Jarecka, Dominika Wróbel-Dudzińska, Urszula Łukasik, Tomasz Żarnowski
THE AIM: The aim of this study was to assess general and ocular profiles of patients with single-localisation changes in visual field. MATERIAL AND METHODS: The study group consisted of 215 Caucasian patients with normal-tension glaucoma with scotoma on single localisation or with preperimetric glaucoma. During regular follow-up visits, ophthalmic examination was carried out and medical history was recorded. The results of the visual field were allocated as paracentral scotomas, arcuate scotomas, peripheral defects, or hemispheric defects...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28764211/a-rare-case-of-topiramate-induced-secondary-acute-angle-closure-glaucoma
#3
Ajit Kamalakar Joshi, Amit Hemant Pathak, Saurabh Dilip Patwardhan, Anil Narayan Kulkarni
Secondary Acute Angle Closure Glaucoma (AACG) is a known side effect of Topiramate (TPM). Here, we present a case report of a 47-year-old male who was started on TPM 25 mg/day for migraine. He presented to the ophthalmology department of our hospital with sudden blurring of vision and colored halos after one day of starting TPM. A high index of suspicion, followed by appropriate investigations and prompt management that helped to manage TPM induced bilateral AACG with quick and complete visual recovery.
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28725291/relationship-between-normal-tension-glaucoma-and-flammer-syndrome
#4
Katarzyna Konieczka, Hyuk Jin Choi, Simone Koch, Franz Fankhauser, Andreas Schoetzau, Dong Myung Kim
BACKGROUND: Besides intraocular pressure, vascular factors play a role in the pathogenesis of glaucomatous optic neuropathy. One of these potential vascular factors is Flammer syndrome. The purpose of the present study was to determine in a Korean population whether signs and symptoms of Flammer syndrome occur more often in normal tension glaucoma patients than in control subjects. METHODS: Two hundred forty-six normal tension glaucoma patients and 1116 control subjects responded to a multiple-choice questionnaire asking about 15 signs and symptoms of Flammer syndrome...
June 2017: EPMA Journal
https://www.readbyqxmd.com/read/28571810/predictive-role-of-neutrophil-to-lymphocyte-ratio-and-platelet-to-lymphocyte-ratio-in-normal-tension-glaucoma
#5
Kursat Atalay, Havva Kaldirim Erdogan, Ahmet Kirgiz, Senay Asik Nacaroglu
As a type of primary open-angle glaucoma, normal-tension glaucoma (NTG) is a health problem that manifests itself with low intraocular pressure (IOP) levels and preserves its importance for public health care. In population-based screenings, which take the IOP levels of 21mmHg as a cut-off for the diagnosis of glaucoma, the diagnosis is usually delayed, and the treatment is started in an advanced stage by the referred ophthalmologists. NTG is associated with some autoimmune conditions and systemic diseases, such as paraproteinemia, nocturnal hypotension, and migraine...
June 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28562545/sumatriptan-induced-angle-closure-glaucoma-a-case-report
#6
Cherng-Ru Hsu, Yi-Hao Chen, Ming-Cheng Tai, Da-Wen Lu
RATIONALE: Drug-induced bilateral angle-closure glaucoma is a rare event and should be treated correctly and promptly to prevent visual loss. PATIENT CONCERNS: We report a rare case of sumatriptan-induced bilateral angle-closure glaucoma in a young woman with migraine, and explore the possible mechanism. DIAGNOSES: We describe the clinical outcome of a patient with sumatriptan-induced bilateral angle-closure glaucoma. The patient presented with bilateral acute elevation of intraocular pressure (IOP) and myopic shift...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28471826/chronic-comorbidities-associated-with-inflammatory-bowel-disease-prevalence-and-impact-on-healthcare-costs-in-switzerland
#7
Caroline Bähler, Alain M Schoepfer, Stephan R Vavricka, Beat Brüngger, Oliver Reich
OBJECTIVE: Inflammatory bowel disease (IBD) was shown to be associated with a variety of chronic comorbidities. We aimed to evaluate the frequency of 21 chronic conditions and compared frequencies in IBD and non-IBD populations. Further, healthcare costs of those (additional) chronic conditions were calculated. PATIENTS AND METHODS: A total of 4791 IBD patients, who were insured at Helsana Insurance Group in 2014, were compared with 1 114 638 individuals without IBD...
August 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28387107/-bilateral-angle-closure-glaucoma-induced-by-topiramate
#8
O Beaudry, V Goncette, N Collignon
Topiramate (TPM) is a drug used in migraine prophylaxis. It is involved in the bilateral angle-closure glaucoma due to idiosyncratic response. This side effect is rare but can lead to irreversible vision loss if it is not recognized in time and if it is not managed immediately by an ophthalmologist.
November 2016: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28268429/identifying-glaucoma-patients-by-applying-multivariate-analyses-of-cardiovascular-signals
#9
Andreas Voss, Claudia Fischer, Cristina Gonzalez Martinez, Eva Koch, Niklas Plange, Kathleen Kunert
Glaucoma is a disease that damages the eye's optic nerve. However, the exact cause of this optic nerve damage is not yet fully understood. Besides the factors of age, genetics and others, such as obesity, medication and migraines, a vascular dysfunction is believed to be a significant factor leading to glaucoma. This study's objective was to investigate whether these vascular dysfunctions could be recognized by analyzing cardiovascular regulation in glaucoma patients. Linear and nonlinear methods were applied to the extracted heart rate (HR), and systolic/ diastolic blood pressure (DBP) time series to discriminate between 35 healthy controls and 20 glaucoma patients...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28251921/clinical-implications-of-the-melanopsin-based-non-image-forming-visual-system
#10
REVIEW
Alexander Ksendzovsky, I Jonathan Pomeraniec, Kareem A Zaghloul, J Javier Provencio, Ignacio Provencio
Since the discovery of the non-image-forming visual system, tremendous research efforts have been dedicated to understanding its mechanisms and functional roles. Original functions associated with the melanopsin system include the photoentrainment of circadian sleep-wake cycles and the pupillary light reflex. Recent findings, however, suggest a much broader involvement of this system in an array of physiologic responses to light. This newfound insight into the underlying function of the non-image-forming system has revealed the many connections to human pathology and attendant disease states, including seasonal affective disorder, migraine, glaucoma, inherited mitochondrial optic neuropathy, and sleep dysregulation of aging...
March 28, 2017: Neurology
https://www.readbyqxmd.com/read/28226599/identifying-glaucoma-patients-by-applying-multivariate-analyses-of-cardiovascular-signals
#11
Andreas Voss, Claudia Fischer, Cristina Gonzalez Martinez, Eva Koch, Niklas Plange, Kathleen Kunert, Andreas Voss, Claudia Fischer, Cristina Gonzalez Martinez, Eva Koch, Niklas Plange, Kathleen Kunert, Claudia Fischer, Kathleen Kunert, Niklas Plange, Cristina Gonzalez Martinez, Eva Koch, Andreas Voss
Glaucoma is a disease that damages the eye's optic nerve. However, the exact cause of this optic nerve damage is not yet fully understood. Besides the factors of age, genetics and others, such as obesity, medication and migraines, a vascular dysfunction is believed to be a significant factor leading to glaucoma. This study's objective was to investigate whether these vascular dysfunctions could be recognized by analyzing cardiovascular regulation in glaucoma patients. Linear and nonlinear methods were applied to the extracted heart rate (HR), and systolic/ diastolic blood pressure (DBP) time series to discriminate between 35 healthy controls and 20 glaucoma patients...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28138165/aetiology-of-headache-in-clinical-ophthalmic-practice-at-a-tertiary-care-hospital-of-karachi
#12
Uzma Fasih, Arshad Shaikh, Nisar Shaikh
OBJECTIVE: To determine the aetiology of headache in patients seen for an ocular examination. METHODS: This cross-sectional, descriptive study was conducted at Ophthalmology Department of Karachi Medical and Dental College, Abbasi Shaheed Hospital, Karachi, from January to December 2014, and comprised patients with headache. Patients were registered through non-probability consecutive sampling technique. A predesigned proforma was used to collect data. Complete ocular examination and investigations were conducted along with neuro-ophthalmological examination...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27978460/clinical-characteristics-of-headache-or-facial-pain-prior-to-the-development-of-acute-herpes-zoster-of-the-head
#13
Hye Lim Lee, Minju Yeo, Gi Hwa Choi, Ji Yeoun Lee, Ji Seon Kim, Dong-Ick Shin, Sang-Soo Lee, Sung-Hyun Lee
OBJECTIVES: When physicians encounter patients with headache or facial pain (preeruptive pain) associated with acute herpes zoster of the head, especially before the appearance of characteristic skin eruptions (preeruptive phase), they typically find it difficult to make clinical impressions and apply appropriate diagnostic or therapeutic procedures. The objectives of this study were to describe the clinical characteristics of headache or facial pain associated with acute herpes zoster of the head and to elucidate the association between the manifestation of these symptoms in the preeruptive phase and incoming herpes zoster...
January 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27941050/effects-of-ocular-and-systemic-factors-on-the-progression-of-glaucomatous-visual-field-damage-in-various-sectors
#14
Ryo Asaoka, Hiroshi Murata, Yuri Fujino, Kazunori Hirasawa, Masaki Tanito, Shiro Mizoue, Kazuhiko Mori, Katsuyoshi Suzuki, Takehiro Yamashita, Kenji Kashiwagi, Atsuya Miki, Nobuyuki Shoji
BACKGROUND/AIM: To investigate the effects of ocular and systemic risk factors for glaucomatous progression in different sectors of the visual field (VF). METHOD: 409 eyes from 268 patients with 10 reliable VFs from the Japanese Archive of Multicentral Databases in Glaucoma (JAMDIG) were investigated. VFs were divided into six sectors (mean total deviation (mTD)s20+, mTDs10-20 and mTDs0-10, >20°, 10-20° and <10° in the superior hemifield, respectively; and mTDi20+, mTDi10-20 and mTDi0-10, >20°, 10-20° and <10° in the inferior hemifield, respectively)...
August 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27813193/the-importance-of-and-potential-for-continuous-monitoring-of-intraocular-pressure
#15
REVIEW
Charles W McMonnies
Monitoring intraocular pressure (IOP) is a critically important part of glaucoma management; however, clinical tonometry predominantly involves sitting postures and is unable to detect variations in response to posture changes, muscular effort, deep respirations and during a wide range of activities, such as playing high wind-resistance instruments and wearing swimming goggles in addition to eye touching and rubbing. For example, the usefulness of 24-hour tonometric phasing may be increased, if nocturnal assessments included side and prone sleeping postures rather than being limited to supine posture tonometry...
May 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/27777505/plasma-endothelin-1-and-single-nucleotide-polymorphisms-of-endothelin-1-and-endothelin-type-a-receptor-genes-as-risk-factors-for-normal-tension-glaucoma
#16
Ewa Kosior-Jarecka, Dominika Wróbel-Dudzińska, Urszula Łukasik, Tin Aung, Chiea Chuen Khor, Janusz Kocki, Tomasz Żarnowski
PURPOSE: The purpose of this study was to determine whether four single nucleotide polymorphisms (SNPs) of endothelin and endothelin receptor type A genes can constitute a risk factor for normal tension glaucoma (NTG) and high tension glaucoma (HTG). METHODS: The study included 160 patients with NTG, 124 patients with HTG, and 165 healthy controls. To analyze the frequency of polymorphic variants of the endothelin EDN gene (K198N) and the endothelin receptor type A gene EDN RA (C1222T, C70G, G231A), DNA was isolated from peripheral blood, and SNP genotyping was performed using the real-time PCR (RT-PCR) method...
2016: Molecular Vision
https://www.readbyqxmd.com/read/27728509/topiramate-induced-angle-closure-glaucoma-in-a-case-of-chronic-migraine
#17
Y S Sirohi, V A Arun, Yatharth Dixit
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27413503/update-on-normal-tension-glaucoma
#18
REVIEW
Jyotiranjan Mallick, Lily Devi, Pradeep K Malik, Jogamaya Mallick
Normal tension glaucoma (NTG) is labelled when typical glaucomatous disc changes, visual field defects and open anterior chamber angles are associated with intraocular pressure (IOP) constantly below 21 mmHg. Chronic low vascular perfusion, Raynaud's phenomenon, migraine, nocturnal systemic hypotension and over-treated systemic hypertension are the main causes of normal tension glaucoma. Goldmann applanation tonometry, gonioscopy, slit lamp biomicroscopy, optical coherence tomography and visual field analysis are the main tools of investigation for the diagnosis of NTG...
April 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27229356/topiramate-associated-non-glaucomatous-visual-field-defects
#19
Sameen Haque, Mohamed Shaffi, Kong C Tang
We report a 34-years-old woman who presented with bilateral incongruous inferior visual field defects after the commencement of topiramate for management of migraine. Investigations did not reveal any underlying angle closure glaucoma, reported in current literature to be associated commonly with topiramate associated visual field defects. The changes in the peripheral visual fields gradually improved over several months after the medication was withdrawn. There were only minor changes persistent on the left side on a background of pre-existing myopia and keratoconus...
September 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27175700/does-migraine-increase-the-risk-of-glaucoma-a-population-based-cohort-study
#20
Hsin-Yi Chen, Cheng-Li Lin, Chia-Hung Kao
This study investigated whether migraine influences the risk of primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) in Taiwan.We retrieved the data analyzed in this study from the National Health Insurance Research Database in Taiwan. We included 17,606 newly diagnosed migraine patients without preexisting glaucoma and randomly selected and matched 70,423 subjects without migraine as the comparison cohort. The same exclusion criteria were also applied to comparison subjects. Multivariate Cox proportion-hazards regression model was used to assess the effects of migraines on the risk of glaucoma after adjusting for demographic characteristics and comorbidities...
May 2016: Medicine (Baltimore)
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