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JOURNAL ARTICLE
S Mandin, L Metilli, M Karrouch, C Lancelon-Pin, J-L Putaux, W Chèvremont, E Paineau, N Hengl, B Jean, F Pignon
An innovative method combining frontal filtration with ultraviolet (UV) curing has been implemented to design cellulosic nanocomposite films with controlled anisotropic textures from nanometric to micrometric length scales. Namely, an aqueous suspension containing poly (ethylene glycol) diacrylate polymer (PEGDA) as a photocurable polymer and cellulose nanocrystals (CNCs) at a 70/30 mass ratio was processed by frontal filtration, followed by in-situ UV-curing in a dedicated cell. This procedure allowed designing nanocomposite films with highly oriented and densely-packed CNCs, homogeneously distributed in a PEGDA matrix over a thickness of ca...
August 1, 2024: Carbohydrate Polymers
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JOURNAL ARTICLE
Todd Olmstead, Jennifer C Spencer, Nicole Kluz, F Benjamin Zhan, Navkiran K Shokar, Michael Pignone
INTRODUCTION: Mailed stool testing for colorectal cancer (CRC) may improve screening uptake and reduce the incidence and mortality of CRC, especially among patients at federally qualified health centers (FQHCs). To expand screening programs it is important to identify cost-effective approaches. METHODS: We developed a decision-analytic model to estimate the cost, effects on screening and patient outcomes (CRCs detected, CRCs prevented, CRC deaths prevented), and cost-effectiveness of implementing a state-wide mailed stool testing program over 5 years among unscreened, age-eligible (aged 50-75 y) patients at FQHCs in Texas...
May 2, 2024: Preventing Chronic Disease
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JOURNAL ARTICLE
Jennifer C Spencer, Michael P Pignone
No abstract text is available yet for this article.
April 29, 2024: JAMA Internal Medicine
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REVIEW
A Szoke, B Pignon, O Godin, A Ferchiou, R Tamouza, M Leboyer, F Schürhoff
PURPOSE OF REVIEW: A global study of multimorbidity in schizophrenia, especially of the association with physical conditions, might offer much needed etiological insights. RECENT FINDINGS: Our review suggests that life-style factors and medication related to schizophrenia are only part of the explanation of the increase in risk for cardiovascular, metabolic, pulmonary disorders, and some cancers. Positive associations with autoimmune disorders (with the exception of rheumatoid arthritis) and epilepsy are promising avenues of research but to date have not been fully exploited...
April 16, 2024: Current Psychiatry Reports
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REVIEW
A Damiani, M Orlandi, C Bruni, G Bandini, G Lepri, C Scaletti, C Ravaglia, F Frassanito, S Guiducci, A Moggi-Pignone, M Matucci-Cerinic, V Poletti, L Tofani, T V Colby, S Bellando Randone, Sara Tomassetti
BACKGROUND: The prognostic and theragnostic role of histopathological subsets in systemic sclerosis interstitial lung disease (SSc-ILD) have been largely neglected due to the paucity of treatment options and the risks associated with surgical lung biopsy. The novel drugs for the treatment of ILDs and the availability of transbronchial cryobiopsy provide a new clinical scenario making lung biopsy more feasible and a pivotal guide for treatment. The aim of our study was to investigate the usefulness of lung biopsy in SSc ILD with a systematic literature review (SLR)...
March 23, 2024: Respiratory Research
#6
JOURNAL ARTICLE
Baptiste Pignon, Joane Matta, Emmanuel Wiernik, Anne Toussaint, Bernd Loewe, Olivier Robineau, Fabrice Carrat, Gianluca Severi, Mathilde Touvier, Clement Gouraud, Charles Ouazana Vedrines, Victor Pitron, Brigitte Ranque, Nicolas Hoertel, Sofiane Kab, Marcel Goldberg, Marie Zins, Cédric Lemogne
BACKGROUND: Identifying factors that predict the course of persistent symptoms that occurred during the COVID-19 pandemic is a public health issue. Modifiable factors could be targeted in therapeutic interventions. OBJECTIVE: This prospective study based on the population-based CONSTANCES cohort examined whether the psychological burden associated with incident persistent symptoms (ie, that first occurred from March 2020) would predict having ≥1 persistent symptom 6-10 months later...
March 15, 2024: BMJ Ment Health
#7
JOURNAL ARTICLE
Salvatore De Caro, Antonella Venezia, Luigia Di Stasio, Donatella Danzi, Domenico Pignone, Gianfranco Mamone, Giuseppe Iacomino
Tritordeum is an amphiploides species resulting from the hybridization between durum wheat ( T. durum ) and wild barley ( H. chilense ). This new cereal is considered a natural crop as it is obtained by traditional breeding techniques. Given its appreciable organoleptic characteristics, agronomic features, presence of interesting components, and good technological properties, Tritordeum is of promising interest for the development of health-oriented foods. In this study, we evaluated two registered Tritordeum cultivars, Bulel and Aucan...
February 22, 2024: Foods (Basel, Switzerland)
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JOURNAL ARTICLE
Giulia Bandini, Alessia Alunno, Filipe Oliveira Pinheiro, Corrado Campochiaro, Ilaria Galetti, Pietro Matucci Cerinic, Barbara Ruaro, Alberto Moggi Pignone, Silvia Bellando Randone, Lorenzo Dagna, Marco Matucci Cerinic, Zsuzsanna H McMahan, Michael Hughes
OBJECTIVES: Proton Pump Inhibitors (PPIs) are widely used in SSc for gastroesophageal reflux disease (GERD). However, there is little evidence to support their empirical use and long-term safety has been questioned. Our objective was to better describe clinicians' attitudes toward PPIs prescription and use in SSc patients. METHODS: Clinicians involved in the care of SSc patients were invited through international physician networks and social media to participate in an online survey...
February 23, 2024: Seminars in Arthritis and Rheumatism
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JOURNAL ARTICLE
Giulia Bandini, Alessia Alunno, Begonya Alcacer-Pitarch, Barbara Ruaro, Ilaria Galetti, Khadija El-Aoufy, Filipe Pinheiro, Giulia Campanaro, Judith Jade, StefanoDi Donato, Lindsay Muir, Alberto Moggi Pignone, Silvia Bellando Randone, Francesco Del Galdo, Zsuzsanna H McMahan, Marco Matucci-Cerinic, Michael Hughes
INTRODUCTION: Digital ulcers (DUs) significantly impact on quality of life and function in patients with systemic sclerosis (SSc). The aim of our survey was to explore patients' perspectives and their unmet needs concerning SSc-DUs. MATERIALS: SSc patients were invited through international patient associations and social media to participate in an online survey. RESULTS: 358 responses were obtained from 34 countries: US (65.6%), UK (11.5%) and Canada (4...
March 2, 2024: Rheumatology
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JOURNAL ARTICLE
Anne Le Coat, Victor Hurpin, Ophélie Pignon, Xavier Fouilland
No abstract text is available yet for this article.
October 2023: La Revue du Praticien
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JOURNAL ARTICLE
Ayisha N Mahama, Courtney N Haller, Jocelyn Labrada, Christie I Idiong, Alex B Haynes, Elizabeth A Jacobs, Joel Tsevat, Michael P Pignone, Adewole S Adamson
IMPORTANCE: Most of the rapid increase in cutaneous melanoma incidence in the US has been localized disease that is treated surgically and is associated with high survival rates. However, little is known about the psychological well-being of survivors in the US. OBJECTIVE: To explore the lived experiences and fear of cancer recurrence among survivors of localized cutaneous melanoma. DESIGN, SETTING, AND PARTICIPANTS: This was a qualitative and survey-based study that used semistructured interviews and the Fear of Cancer Recurrence Inventory short form (FCRI-SF) survey tool with participants recruited from an academic dermatology practice affiliated with the University of Texas, Austin...
February 14, 2024: JAMA Dermatology
#12
JOURNAL ARTICLE
Gemma Lepri, Cosimo Bruni, Lorenzo Tofani, Alberto Moggi-Pignone, Martina Orlandi, Sara Tomassetti, Michael Hughes, Francesco Del Galdo, Rosaria Irace, Oliver Distler, Valeria Riccieri, Yannick Allanore, Ana Maria Gheorghiu, Elise Siegert, Jeska De Vries-Bouwstra, Eric Hachulla, Mohammed Tikly, Nemanja Damjanov, Francois Spertini, Luc Mouthon, Anna-Maria Hoffmann-Vold, Armando Gabrielli, Serena Guiducci, Marco Matucci-Cerinic, Daniel Furst, Silvia Bellando-Randone, Eustar Collaborators
BACKGROUND AND OBJECTIVES: In SSc, ILD is a major cause of morbidity and mortality. We aimed to investigate the performance of DLCO (diffusing capacity of lung carbon monoxide) and FVC (forced vital capacity) delta change (Δ) and baseline values in predicting the development of SSc-ILD. METHODS: Longitudinal data of DLCO, FVC, and ILD on the HRCT of SSc patients from the EUSTAR database were evaluated at baseline (t0 ) and after 12 (±4) (t1 ) and 24 (±4) (t2 ) months...
January 30, 2024: Diagnostics
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JOURNAL ARTICLE
Léa Leclerc, Eric Fakra, Baptiste Pignon, Amine Benyamina, Raphaël Gaillard, Benjamin Rolland
OBJECTIVE: To explore the opinions of French psychiatrists toward the legalization of medical or recreational use of cannabis in France. METHODS: Psycan was an anonymous Internet survey conducted between September 28, 2021 and March 29, 2022, among subscribers of the Encéphale Online community, i.e., approximately 4000 French psychiatrists. Participants were asked to complete a structured questionnaire, collecting their socio-demographic features, clinical experience, opinions toward cannabis legalization, and perceived impact of cannabis derivatives for psychiatric disorders...
February 3, 2024: L'Encéphale
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JOURNAL ARTICLE
Giuseppe D'Andrea, Diego Quattrone, Kathryn Malone, Giada Tripoli, Giulia Trotta, Edoardo Spinazzola, Charlotte Gayer-Anderson, Hannah E Jongsma, Lucia Sideli, Simona A Stilo, Caterina La Cascia, Laura Ferraro, Antonio Lasalvia, Sarah Tosato, Andrea Tortelli, Eva Velthorst, Lieuwe de Haan, Pierre-Michel Llorca, Paulo Rossi Menezes, Jose Luis Santos, Manuel Arrojo, Julio Bobes, Julio Sanjuán, Miguel Bernardo, Celso Arango, James B Kirkbride, Peter B Jones, Bart P Rutten, Jim Van Os, Jean-Paul Selten, Evangelos Vassos, Franck Schürhoff, Andrei Szöke, Baptiste Pignon, Michael O'Donovan, Alexander Richards, Craig Morgan, Marta Di Forti, Ilaria Tarricone, Robin M Murray
BACKGROUND: Incidence of first-episode psychosis (FEP) varies substantially across geographic regions. Phenotypes of subclinical psychosis (SP), such as psychotic-like experiences (PLEs) and schizotypy, present several similarities with psychosis. We aimed to examine whether SP measures varied across different sites and whether this variation was comparable with FEP incidence within the same areas. We further examined contribution of environmental and genetic factors to SP. METHODS: We used data from 1497 controls recruited in 16 different sites across 6 countries...
January 30, 2024: Psychological Medicine
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EDITORIAL
Cédric Lemogne, Clément Gouraud, Charles Ouazana Vedrines, Caroline Pritschkat, Léa Rotenberg, Mathilde Horn, Pascal Cathébras, Alexandra Kachaner, Marc Scherlinger, Thomas de Broucker, Baptiste Pignon, Jean-Christophe Chauvet-Gelinier, Sven Günther, Xavier Gocko, Victor Pitron, Brigitte Ranque
No abstract text is available yet for this article.
January 22, 2024: Journal of Psychosomatic Research
#16
JOURNAL ARTICLE
Emilie Brenaut, Ophélia Godin, Marion Leboyer, Ryad Tamouza, Florence Assan, Baptiste Pignon, Emilie Sbidian
No abstract text is available yet for this article.
January 19, 2024: Journal of Investigative Dermatology
#17
JOURNAL ARTICLE
Pierre A Geoffroy, Valentina Decio, Philippe Pirard, Olivier Bouaziz, Emmanuelle Corruble, Viviane Kovess-Masfety, Michel Lejoyeux, Jonathan Messika, Baptiste Pignon, Vittorio Perduca, Nolwenn Regnault, Sarah Tebeka
INTRODUCTION: Although hospitalisation for COVID-19 is associated with a higher post-discharge risk of mood disorders, including major depressive disorder (MDD) and bipolar disorder (BD), this risk has not been compared to that following hospitalisation for a reason other than COVID-19. METHODS: Using data from France's National Health Data System (SNDS) database, we compared patients hospitalised for mood disorders in the 12 months following COVID-19/another reason hospitalisation...
January 14, 2024: Journal of Affective Disorders
#18
JOURNAL ARTICLE
Gwénaël Le Teuff, Nathalie Cozic, Jean-Christophe Boyer, Valérie Boige, Robert B Diasio, Julien Taieb, Didier Meulendijks, Claire Palles, Matthias Schwab, Maarten Deenen, Carlo R Largiadèr, Anthony Marinaki, Barbara A Jennings, Yvonne Wettergren, Antonello Di Paolo, Eva Gross, Barna Budai, Stephen P Ackland, André B P van Kuilenburg, Howard L McLeod, Gérard Milano, Fabienne Thomas, Marie-Anne Loriot, David Kerr, Jan H M Schellens, Pierre Laurent-Puig, Qian Shi, Jean-Pierre Pignon, Marie-Christine Etienne-Grimaldi
BACKGROUND: Dihydropyrimidine dehydrogenase (DPD) deficiency is the main known cause of life-threatening fluoropyrimidine (FP)-induced toxicities. We conducted a meta-analysis on individual patient data to assess the contribution of deleterious DPYD variants *2A/D949V/*13/HapB3 (recommended by EMA) and clinical factors, for predicting G4-5 toxicity. METHODS: Study eligibility criteria included recruitment of Caucasian patients without DPD-based FP-dose adjustment...
January 15, 2024: British Journal of Cancer
#19
JOURNAL ARTICLE
Frédéric Pignon, Emilie Guilbert, Samuel Mandin, Nicolas Hengl, Mohamed Karrouch, Bruno Jean, Jean-Luc Putaux, Thomas Gibaud, Sebastien Manneville, Theyencheri Narayanan
HYPOTHESIS: Rodlike cellulose nanocrystals (CNCs) exhibit significant potential as building blocks for creating uniform, sustainable materials. However, a critical hurdle lies in the need to enhance existing or devise novel processing that provides improved control over the alignment and arrangement of CNCs across a wide spatial range. Specifically, the challenge is to achieve orthotropic organization in a single-step processing, which entails creating non-uniform CNC orientations to generate spatial variations in anisotropy...
January 4, 2024: Journal of Colloid and Interface Science
#20
JOURNAL ARTICLE
Luna Gargani, Cosimo Bruni, Giancarlo Todiere, Nicola Riccardo Pugliese, Giulia Bandini, Silvia Bellando-Randone, Serena Guiducci, Gennaro D'Angelo, Corrado Campochiaro, Giacomo De Luca, Chiara Stagnaro, Massimo Lombardi, Lorenzo Dagna, Alessia Pepe, Yannick Allanore, Alberto Moggi-Pignone, Marco Matucci-Cerinic
BACKGROUND: Cardiac involvement in systemic sclerosis (SSc) affects the prognosis of the disease. Echocardiography is the first line imaging tool to detect cardiac involvement, but it is not able to routinely detect myocardial fibrosis. Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) is the gold standard for replacement myocardial fibrosis assessment, but its availability is currently limited. AIM: We aimed to assess the clinical and instrumental parameters that would be useful for predicting the presence of LGE-CMR, to achieve a better selection of patients with SSc that could benefit from third-level CMR imaging...
December 23, 2023: Journal of Clinical Medicine
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