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Ganesh Manoharan, Jorge A Belardi, Zhimin Du, Michael Lee, Shubin Qiao, Patrick W Serruys, Stephan Windecker, Bo Xu, Alan Yeung
AIMS: To investigate whether long-term (3-year) clinical outcomes after multivessel treatment with the Resolute zotarolimus-eluting stent (R-ZES) were similar to single-vessel treatment. METHODS AND RESULTS: The RESOLUTE Global Clinical Trial Program enrolled 7618 patients, of whom 1562 underwent multivessel and 6053 single-vessel treatment with the R- ZES. Patients in the multivessel group were more likely to have complex lesions (58% vs 44%, p<0.001). Clinical outcomes were compared using a Cox regression model adjusted by propensity score to account for differences in baseline characteristics...
October 25, 2016: EuroIntervention
Nishant Ganesh Kumar, Adil A Faqih, Michael P Feng, Richard S Miller, Richard A Pierce, Kenneth W Sharp, Michael D Holzman, Benjamin K Poulose
INTRODUCTION: Ventral hernia repair (VHR) is a commonly performed surgical procedure. Unfortunately, long term prospective information about quality of life and outcomes after VHR has been challenging to obtain. Decoupling follow up from clinical visits via patient reported outcomes (PROs) has been proposed as a means of achieving better long term assessments after VHR. The Americas Hernia Society Quality Collaborative (AHSQC) is a national quality improvement (QI) effort in hernia repair which uses PROs to obtain long term follow up...
October 20, 2016: Journal of the American College of Surgeons
S Ganesh Babu, P Aparna, G Satishkumar, Muthupandian Ashokkumar, B Neppolian
A recyclable heterogeneous catalyst has been successfully developed for application in a Fenton-type advanced oxidation process without adding external H2O2. LaFeO3 was prepared from Fe(NO3)3·9H2O and La(NO3)·6H2O by a simple sol-gel method and its catalytic efficiency was evaluated for mineralization of 4-chlorophenol using a Fenton-like process. The mineralization process was carried out under ultrasonication in presence of heterogeneous LaFeO3 catalyst with H2O2 that was produced during ultrasonication...
January 2017: Ultrasonics Sonochemistry
I Ganesh Moorthy, J Prakash Maran, S Ilakya, S L Anitha, S Pooja Sabarima, B Priya
Four factors three level face centered central composite response surface design was employed in this study to investigate and optimize the effect of process variables (liquid-solid (LS) ratio (10:1-20:1ml/g), pH (1-2), sonication time (15-30min) and extraction temperature (50-70°C)) on the maximum extraction yield of pectin from waste Artocarpus heterophyllus (Jackfruit) peel by ultrasound assisted extraction method. Numerical optimization method was adapted in this study and the following optimal condition was obtained as follows: Liquid-solid ratio of 15:1ml/g, pH of 1...
January 2017: Ultrasonics Sonochemistry
Ganesh Kumar Gnanappa, Karina Laohachai, Yishay Orr, Julian Ayer
Anomalous origin of a branch pulmonary artery from the aorta is a rare malformation, accounting for 0.12% of all congenital heart defects. Anomalous origin of the left pulmonary artery from the aorta (ALPA) constitutes a small proportion of these cases. ALPA has been reported to arise from the ascending aorta with various embryologic postulates. We report a case of isolated ALPA arising from the descending aorta in association with a patent ductus arteriosus, to emphasize its embryologic ambiguity.
November 2016: Annals of Thoracic Surgery
Daniela Beccati, Miroslaw Lech, Jennifer Ozug, Nur Sibel Gunay, Jing Wang, Elaine Y Sun, Joël R Pradines, Victor Farutin, Zachary Shriver, Ganesh V Kaundinya, Ishan Capila
Heparan sulfate (HS), a glycosaminoglycan present on the surface of cells, has been postulated to have important roles in driving both normal and pathological physiologies. The chemical structure and sulfation pattern (domain structure) of HS is believed to determine its biological function, to vary across tissue types, and to be modified in the context of disease. Characterization of HS requires isolation and purification of cell surface HS as a complex mixture. This process may introduce additional chemical modification of the native residues...
October 22, 2016: Glycoconjugate Journal
Monish S Raut, Arun Maheshwari, Reena Joshi, Raja Joshi, Sumir Dubey, Ganesh Shivnani, Sujay Shad
No abstract text is available yet for this article.
August 12, 2016: Journal of Cardiothoracic and Vascular Anesthesia
Devin Ganesh, Ben Service, Brian Zirgibel, Kenneth Koval
OBJECTIVES: To assess the utility of the dorsal tangential view (DTV) in detecting intraoperative dorsal screw penetration in distal radius fractures treated with volar locked plating. DESIGN: Retrospective cohort study. SETTING: Academic level 1 trauma center. PATIENTS/PARTICIPANTS: Skeletally mature patients where open reduction internal fixation with volar locked plating was the definitive treatment. A total of twenty-six patients were evaluated...
November 2016: Journal of Orthopaedic Trauma
Ganesh Veerasekar, Krishnan Swaminathan
BACKGROUND: Using technology to track endemic areas of communicable diseases is possible nowadays. Effectual use of such facilities, especially in developing countries, will increase earlier detection of cases as well as aid in the formulation of effective prevention strategies. METHODS: A retrospective data analysis was carried out by collecting the details of patients presented with positive dengue serology, during the outbreak season in the second half of 2012, at Kovai Medical Center and Hospital, Coimbatore, India...
October 2016: Journal of the Association of Physicians of India
Parthopratim Dutta Majumder, Avirupa Ghose, Meenakshi Chidambaram, Sudha K Ganesh, Jyotirmay Biswas
PURPOSE: To report the clinical profile of a series of necrotizing scleritis in an Indian population. METHODS: A retrospective medical record review of 27 consecutive patients with necrotizing scleritis. Patient demographics, ocular and systemic findings, treatment modalities, and visual outcome were recorded. RESULTS: There were 19 males and 8 females (31 eyes) with mean age at presentation of 49.5 years (range: 30-84 years). Underlying immunologically induced disorders was present in 37%...
October 20, 2016: Ocular Immunology and Inflammation
Janine Kamke, Sandra Kittelmann, Priya Soni, Yang Li, Michael Tavendale, Siva Ganesh, Peter H Janssen, Weibing Shi, Jeff Froula, Edward M Rubin, Graeme T Attwood
BACKGROUND: Enteric fermentation by farmed ruminant animals is a major source of methane and constitutes the second largest anthropogenic contributor to global warming. Reducing methane emissions from ruminants is needed to ensure sustainable animal production in the future. Methane yield varies naturally in sheep and is a heritable trait that can be used to select animals that yield less methane per unit of feed eaten. We previously demonstrated elevated expression of hydrogenotrophic methanogenesis pathway genes of methanogenic archaea in the rumens of high methane yield (HMY) sheep compared to their low methane yield (LMY) counterparts...
October 19, 2016: Microbiome
Rajkumar Bharatia, Manoj Chitale, Ganesh Narain Saxena, Raman Ganesh Kumar, Chikkalingaiah, Abhijit Trailokya, Kalpesh Dalvi, Suhas Talele
INTRODUCTION: Hypertension (HTN), being a major risk factor for cardiovascular diseases (CVDs), is an important issue of medical and public health. High blood pressure (BP) is ranked as the third most important risk factor for attributable burden of disease in south Asia (2010). Hypertension (HTN) exerts a substantial public health burden on cardiovascular health status and healthcare systems in India. Uncontrolled hypertension among adults with hypertension is associated with increased mortality...
July 2016: Journal of the Association of Physicians of India
Ganesh Acharya
No abstract text is available yet for this article.
November 2016: Acta Obstetricia et Gynecologica Scandinavica
Harsh Pipalia, Praveen Ganesh, Samarth Shetty, Paul C Salins, Rohan Raut, Kiran Kumar Boyina
Three-dimensional virtual surgery programs are widely available for orthognathic surgery. The advent of imaging software programs has proved to be useful for diagnosis, treatment planning, outcome measurement, and three-dimensional surgical simulation. Complex maxillofacial malformations continue to present challenges in analysis and correction beyond modern technology. Orthomorphic correction for mandibular dysmorphology refers to basal bone movement without any change in dental component. The purpose of this paper is to present a virtual surgery planning for surgeons to perform the orthomorphic surgery with precision and quantification...
October 14, 2016: Journal of Craniofacial Surgery
Ajay Bahl, Parag Barwad, Ganesh Paramasivam
A good contrast echocardiographic study enhances the safety and efficacy of alcohol ablation procedures. Newer generation echocardiographic contrast agents and conventional radiographic contrast agents when used as echocardiographic contrast agents for this purpose are often unsatisfactory. We describe the use of agitated modified gelatin, a cheap and readily available agent that provides excellent echocardiographic images and identifies the myocardium supplied by the targeted septal artery.
September 2016: Indian Heart Journal
Clark K Ho, Ganesh Sriram, Katrina M Dipple
Mathematical modeling approaches have been commonly used in complex signaling pathway studies such as the insulin signal transduction pathway. Our expanded mathematical model of the insulin signal transduction pathway was previously shown to effectively predict glucose clearance rates using mRNA levels of key components of the pathway in a mouse model. In this study, we re-optimized and applied our expanded model to study insulin sensitivity in other species and tissues (human skeletal muscle) with altered protein activities of insulin signal transduction pathway components...
October 11, 2016: Molecular Genetics and Metabolism
Katie N Myers, Giancarlo Barone, Anil Ganesh, Christopher J Staples, Anna E Howard, Ryan D Beveridge, Sarah Maslen, J Mark Skehel, Spencer J Collis
It was recently discovered that vertebrate genomes contain multiple endogenised nucleotide sequences derived from the non-retroviral RNA bornavirus. Strikingly, some of these elements have been evolutionary maintained as open reading frames in host genomes for over 40 million years, suggesting that some endogenised bornavirus-derived elements (EBL) might encode functional proteins. EBLN1 is one such element established through endogenisation of the bornavirus N gene (BDV N). Here, we functionally characterise human EBLN1 as a novel regulator of genome stability...
October 14, 2016: Scientific Reports
Ramachandran Rameshkumar, Sriram Krishnamurthy, Rajesh Nachiappa Ganesh, Subramanian Mahadevan, Parameswaran Narayanan, Ponnarmeni Satheesh, Puneet Jain
BACKGROUND: Septic acute kidney injury (AKI) accounts for more than half of all cases of AKI in critically ill children. The renal histology was found to alter the management in more than two-third of cases of adult acute renal failure. Better insight into the pathogenesis of pediatric septic AKI could be based on developing a clearer appreciation of the histopathological changes. No comprehensive study of the histopathological features of septic AKI in critically ill children has yet been performed...
October 13, 2016: Clinical and Experimental Nephrology
Susana Arrechea, Ana Aljarilla, Pilar de la Cruz, Emilio Palomares, Ganesh D Sharma, Fernando Langa
Two new conjugated acceptor-π-donor-π-acceptor (A-π-D-π-A) porphyrins have been synthesised using 3-ethylrhodanine (1a) or dicyanovinylene (1b) groups as acceptor units. Their optical and electrochemical properties made these materials excellent electron donors along with PC71BM as the acceptor for solution-processed bulk heterojunction organic solar cells. The devices based on 1a:PC71BM (1 : 2) and 1b:PC71BM (1 : 2) processed with CB showed low power conversion efficiencies (PCE) of 2.30% and 2...
October 12, 2016: Nanoscale
Abirami Arasu, Venkatesh Kumaresan, Rajesh Palanisamy, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi, Munuswamy-Ramanujam Ganesh, Jesu Arockiaraj
Antimicrobial peptides (AMPs) are innate molecules that are found in a wide variety of species ranging from bacteria to humans. In recent years, excessive usage of antibiotics resulted in development of multi-drug resistant pathogens which made researchers to focus on AMPs as potential substitute for antibiotics. Lily type mannose-binding lectin is an extended super-family of structurally and evolutionarily related sugar binding proteins. These lectins are well-known AMPs which play important roles in fish defense mechanism...
October 8, 2016: Developmental and Comparative Immunology
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