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Colonic ischemia

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https://www.readbyqxmd.com/read/27921277/surgery-for-acute-exacerbation-of-chronic-mesenteric-ischemia-a-case-report
#1
Shinji Abe, Tomoji Yamakawa, Hideaki Kawashima, Makoto Yoshida, Setsuji Takanashi, Motoya Kashiyama, Masahiro Ishigooka, Yasushige Shingu, Yoshiro Matsui
BACKGROUND: Chronic mesenteric ischemia (CMI) is a rare disease; however, symptomatic CMI has a risk of acute exacerbation without timely revascularization. CASE PRESENTATION: A 54-year-old man who had had postprandial pain for 6 months was admitted to our hospital because of vomiting and diarrhea. Although the celiac and superior mesenteric arteries were occluded at the proximal portion, contrast enhancement of the bowel wall was good in contrast-enhanced computed tomography (CECT)...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27903473/treatment-of-type-ii-endoleak-and-aneurysm-expansion-after-evar
#2
Konstantinos G Moulakakis, Christos Klonaris, John Kakisis, Constantine N Antonopoulos, Andreas Lazaris, George S Sfyroeras, George Mantas, Spyridon N Vasdekis, Elias N Brountzos, George Geroulakos
AIM: The management of type II endoleak causing sac enlargement continues to be a topic of debate. The purpose of this study was to examine and compare the outcomes between open surgical technique with sacotomy and suturing of the feeding vessels to interventional embolization in patients with aneurysm sac expansion after EVAR. MATERIAL-METHODS: Inclusion criteria for intervention in patients with prior EVAR and type II endoleak were: asymptomatic expanding aneurysm sac > 5mm between two consecutive follow-up CTA scans, symptomatic aneurysm sac expansion...
November 26, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27891381/post-colonoscopy-ischaemic-colitis-in-a-patient-without-risk-factors-for-colon-ischemia-a-case-report
#3
Dattatray Balasaheb Solanke, Nirav Madhukant Pipaliya, Alisha Nitin Chaubal, Meghraj Ananda Ingle, Prabha Dilip Sawant
Ischaemic colitis is the most common form of intestinal ischaemia and is more common in the elderly and in the people having risk factors for colonic ischaemia. Colonoscopy procedure itself is a rare cause of ischaemic colitis. Fewer than 20 cases of ischaemic colitis caused by colonoscopy procedure have been reported in the english literature till date. This patient presented to us within hours of routine colonoscopy with rectal bleeding and lower abdominal pain. On repeat colonoscopy, the patient had mucosal oedema and ulcerations in the descending colon and sigmoid colon...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27888039/total-midgut-volvulus-in-adults-with-intestinal-malrotation-report-of-eleven-patients
#4
H Kotobi, V Tan, J Lefèvre, F Duramé, G Audry, Y Parc
OBJECTIVE: Total small-intestinal volvulus with malrotation (TSIVM) classically presents in the neonatal period; it occurs much less frequently in the adult and is often misdiagnosed. Prognosis is directly related to the degree and duration of intestinal ischemia. Our goal is to describe our experience with TSIVM in the adult, to identify any specific findings and to discuss its management. METHOD: Eleven patients who had undergone surgery for TSIVM at three centers between 1992 and 2012 were included...
November 22, 2016: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/27882326/ventricular-fibrillation-induced-cardiac-arrest-results-in-regional-cardiac-injury-preferentially-in-left-anterior-descending-coronary-artery-territory-in-piglet-model
#5
Giridhar Kaliki Venkata, John R Forder, Dan Clark, Andre Shih, Sharda Udassi, Srinivasarao Badugu, Melissa A Lamb, Stacy L Porvasnik, Renata S Shih, Dalia Colon-Lopez, Arno L Zaritsky, Ikram U Haque, Jai P Udassi
Objective. Decreased cardiac function after resuscitation from cardiac arrest (CA) results from global ischemia of the myocardium. In the evolution of postarrest myocardial dysfunction, preferential involvement of any coronary arterial territory is not known. We hypothesized that there is no preferential involvement of any coronary artery during electrical induced ventricular fibrillation (VF) in piglet model. Design. Prospective, randomized controlled study. Methods. 12 piglets were randomized to baseline and electrical induced VF...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27819873/hydrophilic-polymer-associated-ischemic-enterocolitis
#6
Jesus A Chavez, Wei Chen, Wendy L Frankel, Christina A Arnold
Hydrophilic polymer coating of medical devices serves to lubricate the device and prevent device-related complications. The coating can be mechanically disrupted and result in downstream injury via presumed thromboembolism. This process has been reported in the brain, heart, lung, and skin, and has been replicated through animal studies and in vitro histologic processing of the polymer coating. We report the first description of hydrophilic polymer-associated ischemic enterocolitis in a series of 7 specimens (small bowel=2, colon=4, aortic thrombus=1) from 3 patients...
November 4, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27798439/colonic-ischemia-usual-and-unusual-presentations-and-their-management
#7
Ayah Oglat, Eamonn M M Quigley
PURPOSE OF REVIEW: To provide an update on the epidemiology, pathophysiology, clinical presentation, and management of colonic ischemia. RECENT FINDINGS: Formerly regarded as a rare cause of lower gastrointestinal hemorrhage, colonic ischemia is now recognized to be the most common manifestation of intestinal vascular compromise. In contrast to ischemic events in the small intestine wherein thrombotic and embolic events predominate, colonic ischemia typically results from a global reduction in blood flow to the colon and no occlusive lesion(s) are evident...
October 27, 2016: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/27792472/management-of-peritonitis-after-minimally-invasive-colorectal-surgery-can-we-stick-to-laparoscopy
#8
Alessandra Marano, Maria Carmela Giuffrida, Giorgio Giraudo, Luca Pellegrino, Felice Borghi
BACKGROUND: Although laparoscopy is becoming the standard of care for the treatment of colorectal disease, its application in case of postoperative peritonitis is still not widespread. The objective of this article is to evaluate the role of laparoscopy in the management of postoperative peritonitis after elective minimally invasive colorectal resection for malignant and benign diseases. MATERIALS AND METHODS: Between April 2010 and May 2016, 536 patients received primary minimally invasive colorectal surgery at our Department...
October 28, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27721736/transmural-colonic-infarction-after-routine-colonoscopy-in-a-young-patient-without-risk-factors
#9
Maurizio Zizzo, Carolina Castro Ruiz, Lara Ugoletti, Alessandro Giunta, Stefano Bonacini, Lorenzo Manzini, Fabrizio Aguzzoli, Alberto Colognesi, Claudio Pedrazzoli
Colonoscopy is one of the most widely used procedures in medical practice for the diagnosis and treatment of many benign and malignant diseases of the colorectal tract. Colonscopy has become the reference procedure for screening and surveillance of colorectal cancer. The overall rate of adverse events is estimated to be about 2.8 per 1,000 procedures, while complications requiring hospitalization are about 1.9 per 1,000 colonoscopies. Mortality from all causes and colonoscopy-specific mortality are estimated to be 0...
May 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27695179/isolated-naratriptan-associated-ischemic-colitis
#10
Asra Akbar, George Nissan, Priyanka Chaudhry, Priya Rangasamy, Steven Mudrovich
We report a 41-year-old woman who developed histology- and colonoscopy-proven ischemic colitis with the use of naratriptan not exceeding the maximum 2 doses a day and 3 days per week and without a known medical or cardiovascular history. By exclusion of other causes of colonic ischemia, naratriptan was considered the sole causal agent. Discontinuation of naratriptan resulted in a complete clinical recovery. To date, our patient is the youngest known patient to develop ischemic colitis on isolated naratriptan in the setting of no known medical risk factors or predisposing medical condition...
October 2016: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/27684270/the-expanding-role-of-the-bile-acid-receptor-farnesoid-x-in-the-intestine-and-its-potential-clinical-implications
#11
Laurens J Ceulemans, Emilio Canovai, Len Verbeke, Jacques Pirenne, Ricard Farré
Knowledge about the role of farnesoid X receptor (FXR) in the intestine is rapidly expanding. In pre-clinical animal models of inflammatory bowel disease and bile duct ligation, FXR activation has proven to directly target the three pillars of intestinal homeostasis: intestinal permeability, inflammation and bacterial translocation. The protective role of FXR-ligands on this homeostasis has implications for many intestinal pathologies like inflammatory bowel disease, ischemia reperfusion injury, the metabolic syndrome, colon cancer and even diarrhea...
August 10, 2016: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27650341/organ-protection-during-aortic-cross-clamping
#12
REVIEW
Kak Khee Yeung, Menno Groeneveld, Joyce Ja-Ning Lu, Pepijn van Diemen, Vincent Jongkind, Willem Wisselink
Open surgical repair of an aortic aneurysm requires aortic cross-clamping, resulting in temporary ischemia of all organs and tissues supplied by the aorta distal to the clamp. Major complications of open aneurysm repair due to aortic cross-clamping include renal ischemia-reperfusion injury and postoperative colonic ischemia in case of supra- and infrarenal aortic aneurysm repair. Ischemia-reperfusion injury results in excessive production of reactive oxygen species and in oxidative stress, which can lead to multiple organ failure...
September 2016: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/27638992/mesenteric-vein-thrombosis-can-be-safely-treated-with-anticoagulation-but-is-associated-with-significant-sequelae-of-portal-hypertension
#13
Thomas S Maldonado, Sheila N Blumberg, Sharvil U Sheth, Gabriel Perreault, Mikel Sadek, Todd Berland, Mark A Adelman, Caron B Rockman
BACKGROUND: Mesenteric venous thrombosis (MVT) is a relatively uncommon but potentially lethal condition associated with bowel ischemia and infarction. The natural history and long-term outcomes are poorly understood and under-reported. METHODS: A single-institution retrospective review of noncirrhotic patients diagnosed with MVT from 1999 to 2015 was performed using International Classification of Diseases, Ninth Revision and radiology codes. Patients were excluded if no radiographic imaging was available for review...
October 2016: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27637870/-quetiapine-and-anticholinergic-drugs-induced-ischaemic-colitis-a-case-study
#14
P Cuny, M Houot, S Ginisty, S Horowicz, F Plassart, H Mentec, P Eftekhari
INTRODUCTION: The aim of this paper is to underline the need for systematic monitoring of patients treated with anticholinergic antipsychotic drugs. We present the clinical history of a 34-year-old adult, treated with quetiapine in combination with other drugs with anticholinergic effects. CASE REPORT: A 34-year-old male adult had been suffering from bipolar disorder since 2001. He was treated with risperidone, but he was not compliant due to adverse effects, including decreased libido and erectile dysfunction...
September 13, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27552931/single-centre-results-of-total-endovascular-repair-of-complex-aortic-aneurysms-with-custom-made-anaconda-fenestrated-stent-grafts
#15
R Shahverdyan, D Gray, M Gawenda, J Brunkwall
OBJECTIVE: Fenestrated endovascular aneurysm repair (F-EVAR) has increased the number of patients with aneurysmal disease and a short or no existing neck being eligible for endovascular treatment. The aim of the study is to report experience using the Anaconda fenestrated device with special emphasis on target vessel patency and pitfalls with the device. METHODS: Between 2011 and 2016, 48 F-EVAR procedures were performed in 37 males and 11 females under general anaesthesia using the Anaconda custom made device (CMD)...
October 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27532076/clozapine-treated-patients-have-marked-gastrointestinal-hypomotility-the-probable-basis-of-life-threatening-gastrointestinal-complications-a-cross-sectional-study
#16
Susanna Every-Palmer, Mike Nowitz, James Stanley, Eve Grant, Mark Huthwaite, Helen Dunn, Pete M Ellis
BACKGROUND: Gastrointestinal side effects are particularly common with clozapine and occur with other antipsychotics, ranging from mild constipation to fatal bowel obstruction and/or ischemia. While this adverse-effect spectrum has been attributed to 'gastrointestinal hypomotility', gastrointestinal transit times in antipsychotic-treated patients have not previously been measured, making this mechanism speculative. METHODS: Using standardized radiopaque marker ('Metcalf') methods we established colonic transit times of antipsychotic-treated psychiatric inpatients and compared them with population normative values...
March 2016: EBioMedicine
https://www.readbyqxmd.com/read/27474829/combination-of-diagnostic-laparoscopy-and-intraoperative-indocyanine-green-fluorescence-angiography-for-the-early-detection-of-intestinal-ischemia-not-detectable-at-ct-scan
#17
Giovanni Alemanno, Riccardo Somigli, Paolo Prosperi, Carlo Bergamini, Gherardo Maltinti, Alessio Giordano, Andrea Valeri
INTRODUCTION: Acute mesenteric ischemia is the most severe gastrointestinal complication of acute aortic dissection. The timing of diagnosis is of major importance, in fact the recognition of acute mesenteric ischemia often occurs too late due to the presence of unspecific symptoms and lack of reliable exams. Recently, indocyanine green fluorescence angiography has been adopted in order to measure blood perfusion and microcirculation. PRESENTATION OF CASE: We decided to perform a diagnostic laparoscopy with the support of intra-operative near-infrared indocyanine green fluorescence angiography, in order to detect an initial intestinal ischemia in a 68-year-old patient previously treated with a TEVAR procedure for a type-B aortic dissection...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27462231/a-case-report-of-ischemic-stroke-in-a-patient-with-metastatic-gastric-cancer-secondary-to-treatment-with-the-vascular-endothelial-growth-factor-receptor-2-inhibitor-ramucirumab
#18
Michael E Christiansen, Timothy Ingall, Edward C Lew, Ramesh K Ramanathan, Harshita R Paripati
Ramucirumab is an antiangiogenesis agent targeting the vascular endothelial growth factor receptor-2 (VEGFR-2), approved to treat advanced gastric and colon cancer. In clinical trials, it was shown to cause a small increase in arterial thromboembolism compared to placebo, including cerebral and myocardial ischemia, which was not statistically significant. Detailed case reports are lacking and we here present one of the first case reports of stroke secondary to ramucirumab-induced in situ thrombosis.
May 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/27448227/colonic-stenting-for-malignant-colonic-obstruction-with-pneumatosis-intestinalis-a-case-report
#19
Natthawut Phothong, Jirawat Swangsri, Thawatchai Akaraviputh, Vitoon Chinswangwatanakul, Atthaphorn Trakarnsanga
INTRODUCTION: Pneumatosis intestinalis is one of serious conditions following mechanical bowel obstruction. Emergency surgery is generally required to be a definite treatment in these patients of pneumatosis intestinalis, because of its risk of bowel ischemia and perforation. Since the operation in unprepared colon usually resulted in unfavorable outcome, the use of colonic stent is considered one of potential options as a bridge to definitive surgery. Presently, there is no widely published report of using colonic stent in these patients, particularly for stepping to curative surgery...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27445839/hypoxia-reoxygenation-effects-on-ion-transport-across-rat-colonic-epithelium
#20
Sabine Schindele, Ervice Pouokam, Martin Diener
Ischemia causes severe damage in the gastrointestinal tract. Therefore, it is interesting to study how the barrier and transport functions of intestinal epithelium change under hypoxia and subsequent reoxygenation. For this purpose we simulated hypoxia and reoxygenation on mucosa-submucosa preparations from rat distal colon in Ussing chambers and on isolated crypts. Hypoxia (N2 gassing for 15 min) induced a triphasic change in short-circuit current (Isc): a transient decrease, an increase and finally a long-lasting fall below the initial baseline...
2016: Frontiers in Physiology
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