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https://www.readbyqxmd.com/read/27904547/the-effect-of-vitamin-d-administration-on-serum-leptin-and-adiponectin-levels-in-end-stage-renal-disease-patients-on-hemodialysis-with-vitamin-d-deficiency-a-placebo-controlled-double-blind-clinical-trial
#1
Afsoon Emami Naini, Sahar Vahdat, Zahra Parin Hedaiati, Safoura Shahzeidi, Amir Hossein Pezeshki, Hamid Nasri
BACKGROUND: The prevalence of vitamin D deficiency is higher in end-stage renal disease (ESRD) patients compared to healthy populations. This deficiency could lead to several complications with different mechanisms and might result in reduced survival in patients. Leptin and adiponectin are messenger proteins with endocrine secretion from adipocytes and various effects in cellular mechanisms. The goal of this study was to find the effect of vitamin D administration on serum levels of leptin and adiponectin in ESRD patients...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27896419/effects-of-enamel-sealing-on-shear-bond-strength-and-the-adhesive-remnant-index-study-of-three-fluoride-releasing-adhesives-in-combination-with-metal-and-ceramic-brackets
#2
Elisabeth Hofmann, Laura Elsner, Ursula Hirschfelder, Thomas Ebert, Sebastian Hanke
OBJECTIVES: Selected combinations of materials were used to create tooth-adhesive-bracket complexes to evaluate shear bond strength (SBS) and the adhesive remnant index (ARI) with regard to enamel sealing. METHODS: Four adhesive systems also appropriate for use as enamel sealants were combined with four bracket types, resulting in 16 adhesive-bracket combinations, each of which was tested on 15 permanent bovine incisors. Sealant-adhesives included two recently introduced fluoride-releasing systems (Riva bond LC(®) and go!(®)), one established primer (Opal(®) Seal™), and one commonly used adhesive as control (Transbond™ XT)...
November 28, 2016: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/27886691/pharmacotherapy-pearls-for-the-geriatrician-focus-on-oral-disease-modifying-antirheumatic-drugs-including-newer-agents
#3
REVIEW
Ann J Biehl, James D Katz
Providing safe and effective pharmacotherapy to the geriatric patients with rheumatological disorders is an ongoing struggle for the rheumatologist and geriatrician alike. Cohesive communication and partnership can improve the care of these patients and subvert adverse outcomes. Disease-modifying antirheumatic drugs, including methotrexate, hydroxychloroquine, sulfasalazine, and leflunomide, and the newest oral agent for treatment of rheumatoid arthritis, tofacitinib, have distinctive monitoring and adverse effect profiles...
February 2017: Clinics in Geriatric Medicine
https://www.readbyqxmd.com/read/27875056/opioid-nsaid-and-otc-analgesic-medications-for-dental-procedures-pearl-network-findings
#4
Ying Jo Wong, James Keenan, Keith Hudson, Henry Bryan, Frederick Naftolin, Van P Thompson, Ronald G Craig, Don Vena, Damon Collie, Hongyu Wu, Abigail G Matthews, Ashley C Grill, Frederick A Curro
OBJECTIVE: Dental treatment is often categorized as a moderately or severely painful experience; however, no clinical data reported by the patient and dentist currently exists to support this degree of pain. This has contributed possibly to the overprescribing of analgesics, in particular the opioid class of medications. The primary objective of the study was to document the dentists' postprocedural prescriptions and recommendations for analgesic medications and their effectiveness for a 5-day period...
November 2016: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/27871657/surgical-pearls-in-revision-anterior-cruciate-ligament-surgery-when-must-i-stage
#5
REVIEW
Dustin L Richter, Brian C Werner, Mark D Miller
Failed anterior cruciate ligament (ACL) reconstruction is a challenging clinical entity and revision ACL reconstruction is a technically challenging procedure. This article reviews the etiology of ACL failures, the need for appropriate examination and imaging studies, and discusses the technical considerations to allow for a successful revision reconstruction. Furthermore, we elaborate on the decision-making process of when a 2-stage revision is preferred to a single-stage revision.
January 2017: Clinics in Sports Medicine
https://www.readbyqxmd.com/read/27870817/clinical-pearls
#6
Andrew B Mick
No abstract text is available yet for this article.
December 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27870618/spinal-injections-for-pain-management
#7
William E Palmer
Image-guided spinal injection is commonly performed in symptomatic patients to decrease pain severity, confirm the pain generator, and delay or avoid surgery. This article focuses on the radiologist as spine interventionist and addresses the following four topics relevant to the radiologist who performs corticosteroid injections for pain management: (a) the rationale behind corticosteroid injection, (b) the interaction with patients, (c) the role of imaging in procedural selection and planning, and (d) the pearls and pitfalls of fluoroscopically guided injections...
December 2016: Radiology
https://www.readbyqxmd.com/read/27869622/acl-deficiency-increases-forces-on-the-medial-femoral-condyle-and-the-lateral-meniscus-with-applied-rotatory-loads
#8
Lucas S McDonald, James Boorman-Padgett, Robert Kent, Kyle Stone, Thomas L Wickiewicz, Andrew D Pearle, Carl W Imhauser
BACKGROUND: The articular surfaces and menisci act with the anterior cruciate ligament (ACL) to stabilize the knee joint. Their role in resisting applied rotatory loads characteristic of instability events is unclear despite commonly observed damage to these intra-articular structures in the acute and chronic ACL injury settings. METHODS: Ten fresh-frozen human cadaveric knees were mounted to a robotic manipulator. Combined valgus and internal rotation torques were applied in the presence and absence of a 300-N compressive load...
October 19, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27857455/imaging-in-spinal-posterior-epidural-space-lesions-a-pictorial-essay
#9
Foram B Gala, Yashant Aswani
Spinal epidural space is a real anatomic space located outside the dura mater and within the spinal canal extending from foramen magnum to sacrum. Important contents of this space are epidural fat, spinal nerves, epidural veins and arteries. Due to close proximity of posterior epidural space to spinal cord and spinal nerves, the lesions present with symptoms of radiculopathy and/or myelopathy. In this pictorial essay, detailed anatomy of the posterior epidural space, pathologies affecting it along with imaging pearls to accurately diagnose them are discussed...
July 2016: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/27842504/epcam-as-multi-tumour-target-for-near-infrared-fluorescence-guided-surgery
#10
P B A A van Driel, M C Boonstra, H A J M Prevoo, M van de Giessen, T J A Snoeks, Q R J G Tummers, S Keereweer, R A Cordfunke, A Fish, J D H van Eendenburg, B P F Lelieveldt, J Dijkstra, C J H van de Velde, P J K Kuppen, A L Vahrmeijer, C W G M Löwik, C F M Sier
BACKGROUND: Evaluation of resection margins during cancer surgery can be challenging, often resulting in incomplete tumour removal. Fluorescence-guided surgery (FGS) aims to aid the surgeon to visualize tumours and resection margins during surgery. FGS relies on a clinically applicable imaging system in combination with a specific tumour-targeting contrast agent. In this study EpCAM (epithelial cell adhesion molecule) is evaluated as target for FGS in combination with the novel Artemis imaging system...
November 14, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27832924/nasopharyngectomy-with-operating-microscope-a-case-series
#11
Jia Hui Jang, Hiang Khoon Tan, N Gopalakrishna Iyer, Khee Chee Soo, Ngian Chye Tan
BACKGROUND: Nasopharyngectomy for excision of nasopharyngeal tumors is challenging, as access to the nasopharynx is difficult. Recently our institution embarked on two new approaches - robotic nasopharyngectomy and open nasopharyngectomy with operating microscope (NOM) via maxillary swing approach. This article proposes that the novel approach of NOM via maxillary swing aids visualization for resection of locally invasive nasopharyngeal tumors. METHODS: Over a thirteen-month period, eight patients required nasopharyngectomy in our single Asian institution...
September 25, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27832032/accuracy-and-efficiency-of-recording-pediatric-early-warning-scores-using-an-electronic-physiological-surveillance-system-compared-with-traditional-paper-based-documentation
#12
Gerri Sefton, Steven Lane, Roger Killen, Stuart Black, Max Lyon, Pearl Ampah, Cathryn Sproule, Dominic Loren-Gosling, Caitlin Richards, Jean Spinty, Colette Holloway, Coral Davies, April Wilson, Chung Shen Chean, Bernie Carter, E D Carrol
Pediatric Early Warning Scores are advocated to assist health professionals to identify early signs of serious illness or deterioration in hospitalized children. Scores are derived from the weighting applied to recorded vital signs and clinical observations reflecting deviation from a predetermined "norm." Higher aggregate scores trigger an escalation in care aimed at preventing critical deterioration. Process errors made while recording these data, including plotting or calculation errors, have the potential to impede the reliability of the score...
November 9, 2016: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/27822381/clinical-pearls-how-my-patients-taught-me-the-fainting-lark-symptom
#13
A Kuiper, M E van Egmond, M P M Harms, M D Oosterhoff, B van Harten, D A Sival, T J de Koning, M A J Tijssen
BACKGROUND: Compulsive movements, complex tics and stereotypies are frequent, especially among patients with autism or psychomotor retardation. These movements can be difficult to characterize and can mimic other conditions like epileptic seizures or paroxysmal dystonia, particularly when abnormal breathing and cerebral hypoxia are induced. CASE PRESENTATION: We describe an 18-year-old patient with Asperger syndrome who presented with attacks of tonic posturing of the trunk and neck...
2016: Journal of Clinical Movement Disorders
https://www.readbyqxmd.com/read/27816240/systematic-early-obstetrical-assistance-at-calving-i-effects-on-dairy-calf-stillbirth-vigor-and-passive-immunity-transfer
#14
M Villettaz Robichaud, D L Pearl, S M Godden, S J LeBlanc, D B Haley
A critical time for dairy cattle is the perinatal period. Good calving management is critical to reduce periparturient losses and ensure the health of the offspring. Generally, it has been recommended that cows be allowed to calve unassisted when possible, but very few studies have been published that support or refute this general guideline. To investigate the effect of early assistance, a clinical trial enrolled 257 Holstein cows that were observed through the second stage of calving and assigned randomly to 1 of 2 calving interventions: not assisted (NA) or early assistance (EA) during the second stage of parturition...
November 2, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27816238/systematic-early-obstetrical-assistance-at-calving-ii-effects-on-dairy-heifer-calf-growth-health-and-survival-to-weaning
#15
M Villettaz Robichaud, D L Pearl, S M Godden, J Rushen, S J LeBlanc, D B Haley
Good calving management should not only ease the transition of cows into lactation, but also contribute to providing healthy replacement animals for the herd. Difficulty during parturition has been found to be detrimental to the offspring. Because of the association of obstetrical intervention with undesirable outcomes, the general management recommendation for calving is to let cows give birth unassisted whenever possible. Unfortunately, very few studies have investigated the effects of planned early assistance during calving, regardless of whether or not another problem exists...
November 2, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27815844/incidence-and-geographic-distribution-of-succinic-semialdehyde-dehydrogenase-ssadh-deficiency
#16
Savita Verma Attri, Pratibha Singhi, Natrujee Wiwattanadittakul, Jyotindra N Goswami, Naveen Sankhyan, Gajja S Salomons, Jean-Baptiste Roullett, Ryan Hodgeman, Mahsa Parviz, K Michael Gibson, Phillip L Pearl
The incidence of succinic semialdehyde dehydrogenase (SSADH) deficiency, an autosomal recessive inherited disorder of GABA degradation, is unknown. Upon a recent diagnosis of a new family of affected fraternal twins from the Punjabi ethnic group of India, case ascertainment from the literature and our database was done to determine the number of confirmed cases along with their geographic distribution. The probands presented with global developmental delay, infantile onset epilepsy, and a persistent neurodevelopmental disorder upon diagnosis at 10 years of age with intellectual disability, expressive aphasia, and behavioral problems most prominent for hyperactivity...
November 5, 2016: JIMD Reports
https://www.readbyqxmd.com/read/27802943/clinical-pearls
#17
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
November 2016: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
https://www.readbyqxmd.com/read/27800521/continued-elevation-of-interleukin-18-and-interferon-%C3%AE-after-initiation-of-antiretroviral-therapy-and-clinical-failure-in-a-diverse-multicountry-human-immunodeficiency-virus-cohort
#18
Ashwin Balagopal, Nikhil Gupte, Rupak Shivakoti, Andrea L Cox, Wei-Teng Yang, Sima Berendes, Noluthando Mwelase, Cecilia Kanyama, Sandy Pillay, Wadzanai Samaneka, Breno Santos, Selvamuthu Poongulali, Srikanth Tripathy, Cynthia Riviere, Javier R Lama, Sandra W Cardoso, Patcharaphan Sugandhavesa, Richard D Semba, James Hakim, Mina C Hosseinipour, Nagalingeswaran Kumarasamy, Ian Sanne, David Asmuth, Thomas Campbell, Robert C Bollinger, Amita Gupta
Background.  We assessed immune activation after antiretroviral therapy (ART) initiation to understand clinical failure in diverse settings. Methods.  We performed a case-control study in ACTG Prospective Evaluation of Antiretrovirals in Resource-Limited Settings (PEARLS). Cases were defined as incident World Health Organization Stage 3 or 4 human immunodeficiency virus (HIV) disease or death, analyzed from ART weeks 24 (ART24) to 96. Controls were randomly selected. Interleukin (IL)-6, interferon (IFN)-γ-inducible protein-10, IL-18, tumor necrosis factor-α, IFN-γ, and soluble CD14 (sCD14) were measured pre-ART and at ART24 in plasma...
September 2016: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/27789095/deep-venous-thrombosis-prophylaxis-after-unicompartmental-knee-arthroplasty-a-prospective-study-on-the-safety-of-aspirin
#19
Tom Schmidt-Braekling, Andrew D Pearle, David J Mayman, Geoffrey H Westrich, Wenzel Waldstein, Friedrich Boettner
BACKGROUND: Although venous thromboembolism is one of the leading causes of morbidity after knee arthroplasty, little data exist on the risk of deep venous thrombosis (DVT) after unicompartmental knee arthroplasty (UKA). METHODS: We prospectively enrolled 112 patients undergoing UKA to determine the incidence of DVT utilizing aspirin 325 mg twice a day (BID) for 4 weeks postoperatively as DVT prophylaxis. The data were compared with a recent randomized controlled trial of patients undergoing total knee arthroplasty utilizing aspirin and Lovenox in conjunction with pneumatic compression devices...
September 28, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27786570/ulipristal-acetate-for-pre-operative-treatment-of-moderate-to-severe-uterine-fibroids-in-women-of-reproductive-age-in-the-netherlands-cost-minimization-analysis-and-budget-impact-analysis
#20
N Zakiyah, Adi van Asselt, M J Postma
OBJECTIVE: Ulipristal acetate has been found to be non-inferior to other pre-operative treatments of uterine fibroids, particularly leuprolide. The objective of this study was to assess the pharmacoeconomic profile of ulipristal acetate compared to leuprolide for the pre-operative treatment of moderate to severe uterine fibroids in women of reproductive age in The Netherlands. The analysis was performed and applied within the framework of the ulipristal acetate submission for reimbursement in 2012...
October 27, 2016: Journal of Medical Economics
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