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https://www.readbyqxmd.com/read/29342034/atypical-presentation-of-squamous-papilloma
#1
Poorav Patel, Michael Hemond, Rona Z Silkiss
No abstract text is available yet for this article.
January 16, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29341284/atypical-presentation-of-eosinophilic-annular-erythema-in-a-5-year-old-girl
#2
A Neuberger, A Enk, F Toberer
A 5-year-old female presented with a 1-year history of slightly pruritic erythematous annular plaques covering her trunk and limbs (Figure 1). The remaining integument as wells as the mucous membranes were not affected. The lesions persisted for about one week slowly developing a more violaceous hue before disappearing. This article is protected by copyright. All rights reserved.
January 17, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29340602/emergence-of-blactx-m-55-associated-with-fosa-rmtb-and-mcr-gene-variants-in-escherichia-coli-from-various-animal-species-in-france
#3
Agnese Lupo, Estelle Saras, Jean-Yves Madec, Marisa Haenni
Objectives: In Asian countries, blaCTX-M-55 is the second most common ESBL-encoding gene. blaCTX-M-55 frequently co-localizes with fosA and rmtB genes on epidemic plasmids, which remain sporadic outside Asia. During 2010-13, we investigated CTX-M-55-producing Escherichia coli isolates and their co-resistance to fosfomycin, aminoglycosides, fluoroquinolones and colistin as part of a global survey of ESBLs in animals in France. Methods: blaCTX-M-55, fosA, rmtB and plasmidic quinolone and colistin resistance genes were characterized by PCR, sequencing and hybridization experiments...
January 10, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29340258/atypical-initial-presentation-of-painful-muscle-cramps-in-a-patient-with-amyotrophic-lateral-sclerosis-a-case-report-and-brief-review-of-the-literature
#4
Aaron R Kuzel, Muhammad Uzair Lodhi, Intekhab Askari Syed, Mustafa Rahim
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized clinically by progressive muscle weakness that can occur proximally or distally in either the upper or lower extremities. It includes both upper motor neuron signs (spasticity, hyperreflexia, clonus, and Babinski sign) and lower motor neuron signs (atrophy, weakness, and muscle fasciculation). Initial presentation of progressively painful muscle cramps should lead the physician to screen for other signs of amyotrophic lateral sclerosis...
November 10, 2017: Curēus
https://www.readbyqxmd.com/read/29340125/rare-presentation-of-refractory-thrombotic-thrombocytopenic-purpura-jejunal-stricture
#5
Prabath K Abeysundara, Inoshi Athukorala, K P C Dalpatadu, Karthiha Balendran, M D S A Dilrukshi, Gmo Fernando
Thrombotic thrombocytopenic purpura is a rare thrombotic disease characterized by episodes of thrombocytopenia and microangiopathic hemolytic anemia due to disseminated microvascular thrombosis. Thrombotic thrombocytopenic purpura was first described in 1924 by Moschowitz as a disease presenting with a pentad of signs and symptoms (anemia, thrombocytopenia, fever, hemiparesis and hematuria). Previous studies have described atypical manifestations of thrombotic thrombocytopenic purpura such as hemolysis, anemia and thrombosis...
October 1, 2017: International Journal of Hematology-oncology and Stem Cell Research
https://www.readbyqxmd.com/read/29339964/cerebral-venous-thrombosis-with-papilloedema-secondary-to-skull-base-plasmacytoma
#6
Peter W MacIntosh, Amy Y Lin, Jin Suh Kim, Fernando D Testai, Heather E Moss
A 60-year-old woman with history of multiple myeloma was in remission after stem cell transplant 6 years prior. She was undergoing work-up for headaches that were thought to be secondary to a right mastoiditis seen on magnetic resonance imaging (MRI). On routine eye exam, papilloedema was noted. A lumbar puncture was performed, with elevated opening pressure with normal constituents. She was an atypical age for idiopathic intracranial hypertension, and her mastoiditis raised concern for secondary cerebral venous sinus thrombosis...
October 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/29339529/management-of-endocrine-disease-atypical-femoral-fractures-risks-and-benefits-of-long-term-treatment-of-osteoporosis-with-anti-resorptive-therapy
#7
Robert Adler
Modern osteoporosis treatment began in the mid-1990's with the approval of amino-bisphosphonates, anti-resorptive agents that have been shown to decrease osteoporotic fracture risk by about half. In 2005, the first cases of atypical femoral fractures (AFF), occurring in the shaft of the femur, were reported. Since then, more cases have been found, leading to great concern among patients and a dramatic decrease in bisphosphonate prescribing. The pathogenesis and incidence of AFF are reviewed herein. Management and an approach to prevention or early detection of AFF are also provided...
January 16, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29339506/development-and-retention-of-a-primordial-moonlighting-pathway-of-protein-modification-in-the-absence-of-selection-presents-a-puzzle
#8
Xinyun Cao, Yaoqin Hong, Lei Zhu, Yuanyuan Hu, John E Cronan
Lipoic acid is synthesized by a remarkably atypical pathway in which the cofactor is assembled on its cognate proteins. An octanoyl moiety diverted from fatty acid synthesis is covalently attached to the acceptor protein, and sulfur insertion at carbons 6 and 8 of the octanoyl moiety form the lipoyl cofactor. Covalent attachment of this cofactor is required for function of several central metabolism enzymes, including the glycine cleavage H protein (GcvH). In Bacillus subtilis, GcvH is the sole substrate for lipoate assembly...
January 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29339322/endoscopic-endonasal-craniofacial-surgery-for-recurrent-skull-base-meningiomas-involving-the-pterygopalatine-fossa-the-infratemporal-fossa-the-orbit-and-the-paranasal-sinus
#9
Masahiro Shin, Masaaki Shojima, Kenji Kondo, Hirotaka Hasegawa, Shunya Hanakita, Akihiro Ito, Taichi Kin, Nobuhito Saito
OBJECT: Skull base meningiomas carry a non-negligible risk of recurrence. In particular, those arising from the sphenoid wings or middle cranial fossa penetrate into extracranial regions, uncommonly showing massive expansion into the craniofacial regions on recurrence. The role of endoscopic endonasal surgery for those intractable lesions remains unclear. METHODS: We performed endoscopic endonasal craniofacial surgery for 8 recurrent meningiomas invading into the pterygopalatine fossa, infratemporal fossa, nasopharynx, paranasal sinus, or orbit, comprising 2 meningothelial and 1 fibrous meningiomas (WHO grade I), 3 atypical and 1 clear cell meningiomas (grade II), and 1 anaplastic meningioma (grade III)...
January 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29339179/primary-diffuse-leptomeningeal-atypical-teratoid-rhabdoid-tumor-diagnosed-by-cerebrospinal-fluid-cytology-case-report-with-molecular-genetic-analysis
#10
Ran Tomomasa, Satoshi Nakata, Sumihito Nobusawa, Keishi Horiguchi, Nozomi Matsumura, Hayato Ikota, Junko Hirato, Yuhei Yoshimoto, Hideaki Yokoo
Atypical teratoid/rhabdoid tumors (AT/RT) are rare malignant neoplasms that mainly affect infants and young children, and are typically located in the cerebellar hemispheres. These tumors are histologically characterized by varying proportions of rhabdoid cells, and nuclear INI1 immunonegativity. Here, we report a case of a 15-year-old male with primary diffuse leptomeningeal AT/RT. The patient had symptoms similar to those of meningitis. Magnetic resonance imaging revealed leptomeningeal thickening. Cytological examination using cerebrospinal fluid was repeatedly performed and revealed rhabdoid cells with loss of INI1 reactivity, and shortly after, the diagnosis of AT/RT was confirmed by tissue biopsy...
January 12, 2018: Human Pathology
https://www.readbyqxmd.com/read/29339004/differential-activation-of-brain-areas-in-children-with-developmental-coordination-disorder-during-tasks-of-manual-dexterity-an-ale-meta-analysis
#11
REVIEW
I Fuelscher, K Caeyenberghs, P G Enticott, J Williams, J Lum, C Hyde
Recent neuroimaging studies have reported atypical neural activation in children with Developmental Coordination Disorder (DCD) during tasks assessing manual dexterity. However, small sample sizes and subtle differences in task parameters have led to inconsistent findings, rendering interpretation difficult. The aim of the present meta-analysis was to quantitatively summarize this body of evidence using activation likelihood estimation (ALE) analysis to identify reliable regions of differential neural activation in children with DCD, compared to age-matched controls...
January 12, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29338853/atypical-fractures-an-issue-of-concern-or-a-myth
#12
Mohammad Al-Ashqar, Michalis Panteli, Gautam Chakrabarty, Peter V Giannoudis
Atypical Femoral Fractures (AFF) represent fractures located between the lesser trochanter and the supracondylar flare of a femur. An increasing pool of evidence supports their association with the prolonged use of bisphosphonates, even though a direct correlation is yet to be proved. The purpose of this review is to encapsulate the current evidence associating bisphosphonate use and the development of AFFs, the clinical features related to their presentation, as well as to report the armamentarium of strategies available in the prevention and treatment of AFFs...
December 16, 2017: Injury
https://www.readbyqxmd.com/read/29338455/current-treatment-options-for-meningioma
#13
Caroline Apra, Matthieu Peyre, Michel Kalamarides
With an annual incidence of 5/100,000, meningioma is the most frequent primary tumor of the central nervous system. Risk factors are radiotherapy and hormone intake. Most meningiomas are grade I benign tumors, but up to 15% are atypical and 2% anaplastic according to the WHO 2016 histological criteria. Areas covered: This review details the current standard therapy based on international guidelines and recent literature, and describes new approaches developed to treat refractory cases. First-line treatments are observation and surgery, but adjuvant radiotherapy/radiosurgery is discussed for atypical and indicated for anaplastic meningiomas...
January 17, 2018: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/29338279/the-chondrocoracoideus-muscle-a-rare-anatomical-variant-of-the-pectoral-area
#14
Dionysios Venieratos, Alexandros Samolis, Maria Piagkou, Stergios Douvetzemis, Alexandrina Kourotzoglou, Kontantinos Natsis
OBJECTIVE: The study adds important information regarding the descriptive anatomy of a very rarely reported unilateral chondrocoracoideus muscle (of Wood). Additionally it highlights the concomitant muscular and neural alterations. CASE REPORT: The current case presents the occurrence of a chondrocoracoideus muscle situated left-sided, as an extension of the abdominal portion of the pectoralis major muscle (PM). The chondrocoracoideus coexisted with a contralateral atypical PM, partially blended with the clavicular fibers of the deltoid muscle...
November 2017: Acta Medica Academica
https://www.readbyqxmd.com/read/29337704/the-what-when-and-how-in-performing-and-interpreting-microbiological-diagnostic-tests-in-skin-and-soft-tissue-infections
#15
Carolina Navarro-San Francisco, Patricia Ruiz-Garbajosa, Rafael Cantón
PURPOSE OF REVIEW: To summarize and classify the most recent and relevant microbiological studies for each type of skin and soft tissue infection (SSTI). RECENT FINDINGS: Following Infectious Diseases Society of America and Food and Drug Administration classifications of SSTIs, we differentiate between two large groups, the superficial or uncomplicated infections and the complicated infections with deep involvement. It is not usually necessary to obtain microbiological samples in uncomplicated infections, except in cases of recurrences or for epidemiological control purposes...
January 11, 2018: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/29337454/-osteoporosis
#16
Brigitte Uebelhart, Serge Ferrari
The risk for a second fracture within two years after a first one is high. Ten years denosumab treatment show favorable results with a risk of early vertebral fractures in patients with prevalent vertebral fractures when treatment is stopped. Teriparatide is more effective than risedronate to prevent vertebral and clinical fractures in high risk patients. Romosozumab acts as an anabolic agent in osteoporosis. Atypical femoral fractures associated with bisphosphonate treatment could be more frequent in patients with particular anatomical features...
January 10, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29337407/insufficient-sleep-syndrome-an-unrecognized-but-important-clinical-entity
#17
Jun Kohyama, Yuki Anzai, Makoto Ono, Ai Kishino, Keita Tamanuki, Kazuma Takada, Kento Inoue, Maho Horiuchi, Yoshiho Hatai
BACKGROUND: In the Tokyo Bay Urayasu Ichikawa Medical Centre, a sleep clinic for adults and children was established in August 2012. As few sleep clinics are available in Japan that are specifically for children, this clinic provides the opportunity to provide data on child patients who have been suffering from sleep problems and who visited the sleep clinic. METHODS: Records of patients who visited the sleep clinic at the Tokyo Bay Urayasu Ichikawa Medical Centre at the age of 20 years or younger on their first visit were retrospectively examined, and their initial and final diagnoses were examined...
January 16, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29336692/the-first-serological-study-of-q-fever-in-humans-in-lebanon
#18
Mayssaa Fawaz Dabaja, Grazia Greco, Sara Villari, Ali Bayan, Gesualdo Vesco, Valeria Gargano, Maria Arnone, Mohamad Hneino, Rossella Lelli, Mohamad Ezzedine, Atika Berry, Hussein Mortada, Maria Tempesta, Mohamad Mortada
OBJECTIVE: The aim of this study was to estimate, for the first time, the human seroprevalence of Q fever in Lebanon, by assessing the presence of antibodies against the causative agent, Coxiella burnetii. A total number of 421 serum samples (226 females and 196 males) were collected in February 2015 from hospitals and laboratories dispersed in five Lebanese provinces: Akkar, Bekaa, Mount Lebanon, Nabatieh, and South Lebanon. METHODS: Serial testing approach was used...
January 16, 2018: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29336312/apocrine-mixed-tumour-on-the-abdomen-an-atypical-location
#19
Shoko Mai, Yasuyuki Fujita, Tatsurou Sugai, Keisuke Imafuku, Hiroo Hata, Satoru Shinkuma, Toshifumi Nomura, Naoki Kawagishi, Hiroshi Shimizu
No abstract text is available yet for this article.
January 16, 2018: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29335879/current-approaches-and-new-developments-in-the-pharmacological-management-of-tourette-syndrome
#20
REVIEW
Julio Quezada, Keith A Coffman
Tourette syndrome (TS) is a neurodevelopmental disorder of unknown etiology characterized by spontaneous, involuntary movements and vocalizations called tics. Once thought to be rare, TS affects 0.3-1% of the population. Tics can cause physical discomfort, emotional distress, social difficulties, and can interfere with education and desired activities. The pharmacologic treatment of TS is particularly challenging, as currently the genetics, neurophysiology, and neuropathology of this disorder are still largely unknown...
January 15, 2018: CNS Drugs
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