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https://www.readbyqxmd.com/read/28933736/pulsed-polarization-based-nox-sensors-of-ysz-films-produced-by-the-aerosol-deposition-method-and-by-screen-printing
#1
Jörg Exner, Gaby Albrecht, Daniela Schönauer-Kamin, Jaroslaw Kita, Ralf Moos
The pulsed polarization technique on solid electrolytes is based on alternating potential pulses interrupted by self-discharge pauses. Since even small concentrations of nitrogen oxides (NOx) in the ppm range significantly change the polarization and discharge behavior, pulsed polarization sensors are well suited to measure low amounts of NOx. In contrast to all previous investigations, planar pulsed polarization sensors were built using an electrolyte thick film and platinum interdigital electrodes on alumina substrates...
July 26, 2017: Sensors
https://www.readbyqxmd.com/read/28924507/awareness-about-antibiotic-resistance-in-a-self-medication-user-group-from-eastern-romania-a-pilot-study
#2
Gabi Topor, Ionela-Alina Grosu, Cristina Mihaela Ghiciuc, Aurel Lulu Strat, Cătălina Elena Lupuşoru
BACKGROUND: Awareness about antibiotic resistance depends on the attitudes and information about antibiotic resistance of both patients and physicians. Persons who practice self-medication are at high risk of also self-medicating with antibiotics. The purpose of the present study was to evaluate the awareness about antibiotic resistance by investigating the practice in a group of self-medication users in a sample of adults in Romania and the variables associated with such practice. MATERIAL AND METHODS: A cross-sectional self-filled questionnaire based study was conducted from December 2016 through January 2017 amongst 218 self-medication users (SMUG)...
2017: PeerJ
https://www.readbyqxmd.com/read/28922389/comprehensive-metabolic-characterization-of-serum-osteocalcin-action-in-a-large-non-diabetic-sample
#3
Lukas Entenmann, Maik Pietzner, Anna Artati, Anke Hannemann, Ann-Kristin Henning, Gabi Kastenmüller, Henry Völzke, Matthias Nauck, Jerzy Adamski, Henri Wallaschofski, Nele Friedrich
Recent research suggested a metabolic implication of osteocalcin (OCN) in e.g. insulin sensitivity or steroid production. We used an untargeted metabolomics approach by analyzing plasma and urine samples of 931 participants using mass spectrometry to reveal further metabolic actions of OCN. Several detected relations between OCN and metabolites were strongly linked to renal function, however, a number of associations remained significant after adjustment for renal function. Intermediates of proline catabolism were associated with OCN reflecting the implication in bone metabolism...
2017: PloS One
https://www.readbyqxmd.com/read/28888650/detection-of-rat-hepatitis-e-virus-in-wild-norway-rats-rattus-norvegicus-and-black-rats-rattus-rattus-from-11-european-countries
#4
René Ryll, Samuel Bernstein, Elisa Heuser, Mathias Schlegel, Paul Dremsek, Maxi Zumpe, Sandro Wolf, Michel Pépin, Daniel Bajomi, Gabi Müller, Ann-Charlotte Heiberg, Carina Spahr, Johannes Lang, Martin H Groschup, Hermann Ansorge, Jona Freise, Sebastian Guenther, Kristof Baert, Francisco Ruiz-Fons, Jiri Pikula, Nataša Knap, Ιoannis Tsakmakidis, Chrysostomos Dovas, Stefania Zanet, Christian Imholt, Gerald Heckel, Reimar Johne, Rainer G Ulrich
Rat hepatitis E virus (HEV) is genetically only distantly related to hepeviruses found in other mammalian reservoirs and in humans. It was initially detected in Norway rats (Rattus norvegicus) from Germany, and subsequently in rats from Vietnam, the USA, Indonesia, China, Denmark and France. Here, we report on a molecular survey of Norway rats and Black rats (Rattus rattus) from 12 European countries for ratHEV and human pathogenic hepeviruses. RatHEV-specific real-time and conventional RT-PCR investigations revealed the presence of ratHEV in 63 of 508 (12...
September 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28885991/chronic-diarrhea-and-metabolic-acidosis-associated-with-topiramate-use
#5
Gaby S Gil, Ana Caballes, Estuardo Saravia F, Noella Boma
No abstract text is available yet for this article.
September 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28874533/type-1-diabetes-induction-in-humanized-mice
#6
Shulian Tan, Yang Li, Jinxing Xia, Chun-Hui Jin, Zheng Hu, Gaby Duinkerken, Yuying Li, Mohsen Khosravi Maharlooei, Estefania Chavez, Grace Nauman, Nichole Danzl, Maki Nakayama, Bart O Roep, Megan Sykes, Yong-Guang Yang
There is an urgent and unmet need for humanized in vivo models of type 1 diabetes to study immunopathogenesis and immunotherapy, and in particular antigen-specific therapy. Transfer of patient blood lymphocytes to immunodeficient mice is associated with xenogeneic graft-versus-host reactivity that complicates assessment of autoimmunity. Improved models could identify which human T cells initiate and participate in beta-cell destruction and help define critical target islet autoantigens. We used humanized mice (hu-mice) containing robust human immune repertoires lacking xenogeneic graft-versus-host reactivity to address this question...
September 5, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28846683/acylcarnitines-profile-best-predicts-survival-in-horses-with-atypical-myopathy
#7
François Boemer, Johann Detilleux, Christophe Cello, Hélène Amory, Christel Marcillaud-Pitel, Eric Richard, Gaby van Galen, Gunther van Loon, Laurence Lefère, Dominique-Marie Votion
Equine atypical myopathy (AM) is caused by hypoglycin A intoxication and is characterized by a high fatality rate. Predictive estimation of survival in AM horses is necessary to prevent unnecessary suffering of animals that are unlikely to survive and to focus supportive therapy on horses with a possible favourable prognosis of survival. We hypothesized that outcome may be predicted early in the course of disease based on the assumption that the acylcarnitine profile reflects the derangement of muscle energetics...
2017: PloS One
https://www.readbyqxmd.com/read/28841625/american-society-of-maxillofacial-surgeons-2006-to-2016-another-decade-of-excellence-in-education-and-research
#8
Gaby Doumit, Ali Totonchi, Andy Wexler, Arun K Gosain
Over the past 10 years, the American Society of Maxillofacial Surgeons (ASMS) has continued to advance to meet its mission of being the premier organization to represent maxillofacial and pediatric plastic surgery in the United States. These advances are focused on education of its members, to include the American Society of Maxillofacial Surgeons basic course, the preconference symposium, the annual meeting, two basic maxillofacial courses per year, advanced maxillofacial courses, a boot camp for craniofacial fellows, a cleft course, quarterly webinars, sponsored fellowships, a visiting professorship, and the ASMS journal...
September 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28841621/analysis-of-craniofacial-remodeling-in-the-aging-midface-using-reconstructed-three-dimensional-models-in-paired-individuals
#9
Mihiran Karunanayake, Frederick To, Johnny I Efanov, Gaby Doumit
BACKGROUND: Aging leads to a panoply of changes of facial morphology. The present study was conducted to analyze modifications of the facial skeleton with aging, using high-resolution imaging and comparing the same individuals at two time points. METHODS: The electronic medical record system was reviewed since its inception in 2001 for patients for whom two computed tomographic scans of the midface were obtained at least 9 years apart. The computed tomographic scans were converted into three-dimensional craniofacial models for each patient, using the initial and the follow-up computed tomographic scan data...
September 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28829745/everolimus-eluting-bioresorbable-scaffolds-in-patients-with-coronary-artery-disease-results-from-the-german-austrian-absorb-registry-gabi-r
#10
Holger M Nef, Jens Wiebe, Johannes Kastner, Julinda Mehilli, Thomas Münzel, Christoph Naber, Till Neumann, Gert Richardt, Axel Schmermund, Jochen Wöhrle, Ralf Zahn, Thomas Riemer, Stephan Achenbach, Christian W Hamm
AIMS: To analyze procedural results and mid-term safety of everolimus-eluting bioresorbable vascular scaffolds (BVS) used for percutaneous coronary intervention in a large all-comer cohort from the German-Austrian ABSORB Registry (GABI-R). METHODS AND RESULTS: A total of 3231 patients were included in this prospective, observational, multicentre study (Clinicaltrial.gov NCT02066623) of consecutive patients undergoing BVS implantation between November 2013 and January 2016...
August 22, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28829439/an-integrated-expression-atlas-of-mirnas-and-their-promoters-in-human-and-mouse
#11
Derek de Rie, Imad Abugessaisa, Tanvir Alam, Erik Arner, Peter Arner, Haitham Ashoor, Gaby Åström, Magda Babina, Nicolas Bertin, A Maxwell Burroughs, Ailsa J Carlisle, Carsten O Daub, Michael Detmar, Ruslan Deviatiiarov, Alexandre Fort, Claudia Gebhard, Daniel Goldowitz, Sven Guhl, Thomas J Ha, Jayson Harshbarger, Akira Hasegawa, Kosuke Hashimoto, Meenhard Herlyn, Peter Heutink, Kelly J Hitchens, Chung Chau Hon, Edward Huang, Yuri Ishizu, Chieko Kai, Takeya Kasukawa, Peter Klinken, Timo Lassmann, Charles-Henri Lecellier, Weonju Lee, Marina Lizio, Vsevolod Makeev, Anthony Mathelier, Yulia A Medvedeva, Niklas Mejhert, Christopher J Mungall, Shohei Noma, Mitsuhiro Ohshima, Mariko Okada-Hatakeyama, Helena Persson, Patrizia Rizzu, Filip Roudnicky, Pål Sætrom, Hiroki Sato, Jessica Severin, Jay W Shin, Rolf K Swoboda, Hiroshi Tarui, Hiroo Toyoda, Kristoffer Vitting-Seerup, Louise Winteringham, Yoko Yamaguchi, Kayoko Yasuzawa, Misako Yoneda, Noriko Yumoto, Susan Zabierowski, Peter G Zhang, Christine A Wells, Kim M Summers, Hideya Kawaji, Albin Sandelin, Michael Rehli, Yoshihide Hayashizaki, Piero Carninci, Alistair R R Forrest, Michiel J L de Hoon
MicroRNAs (miRNAs) are short non-coding RNAs with key roles in cellular regulation. As part of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) project, we created an integrated expression atlas of miRNAs and their promoters by deep-sequencing 492 short RNA (sRNA) libraries, with matching Cap Analysis Gene Expression (CAGE) data, from 396 human and 47 mouse RNA samples. Promoters were identified for 1,357 human and 804 mouse miRNAs and showed strong sequence conservation between species...
September 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/28828118/gastrointestinal-bleeding-from-supraduodenal-artery-with-aberrant-origin
#12
Qiong Han, Chenghao Qian, Gaby Gabriel, Steven Krohmer, Driss Raissi
Angiography and endovascular embolization play an important role in controlling acute arterial upper gastrointestinal hemorrhage, particularly when endoscopic intervention fails to do so. In our case, the patient presented with recurrent life-threatening bleed in spite of multiple prior endoscopic interventions and gastroduodenal artery embolization. Our teaching points focus on the role of angiography in acute upper gastrointestinal bleed and when to conduct empiric embolization, while reviewing the supraduodenal artery as an atypical but important potential culprit for refractory upper gastrointestinal bleed...
September 2017: Radiology case reports
https://www.readbyqxmd.com/read/28825894/adhesion-and-invasion-to-epithelial-cells-and-motility-of-extended-spectrum-%C3%AE-lactamase-producing-escherichia-coli-reveal-st131-superiority-a-comparative-in-vitro-study-of-extraintestinal-pathogenic-e-coli-lineages
#13
Kira Kondratyeva, Ayala Wollman, Gabi Gerlitz, Shiri Navon-Venezia
PURPOSE: Extended-spectrum β-lactamase (ESBL)-producing extraintestinal pathogenic Escherichia coli (ExPEC) sequence type ST131 is pandemic, and it is the major contributor to antibiotic resistance in E. coli. Despite its epidemiological superiority, the physiological reasons that decipher its success remain elusive. We aimed to compare the adhesion, invasion and motility potential of ST131 versus other E. coli lineages. METHODOLOGY: In this in vitro comparative study, 14 ESBL-producing ExPEC community-onset bacteremia isolates were chosen from a reported clinical collection (Karfunkel D, Carmeli Y, Chmelnitsky I, Kotlovsky T, Navon-Venezia S...
September 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28815850/editorial
#14
EDITORIAL
Gaby Hirsbrunner
No abstract text is available yet for this article.
August 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28797657/systematic-review-of-transabdominal-cerclage-placed-via-laparoscopy-for-the-prevention-of-preterm-birth
#15
REVIEW
Gaby N Moawad, Paul Tyan, Tracey Bracke, Elias D Abi Khalil, Vicky Vargas, Alexis Gimovsky, Cherie Marfori
Preterm birth is the leading cause of neonatal mortality and morbidity. Multiple interventions have been put in place to minimize this occurrence. Despite current recommendations including medical management, cervical length screening, and transvaginal cerclage a substantial number of women still experience preterm birth. For those patients, experts recommend a transabdominal cerclage. In our systematic review, we compare 26 studies (1116 patients) on transabdominal cerclage placed via laparotomy (TAC-lap) to 15 studies (728 patients) on transabdominal cerclage placed via laparoscopy (TAC-lsc)...
August 7, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28793186/an-engineered-optogenetic-switch-for-spatiotemporal-control-of-gene-expression-cell-differentiation-and-tissue-morphogenesis
#16
Lauren Polstein, Mark Juhas, Gabi Hanna, Nenad Bursac, Charles A Gersbach
The precise spatial and temporal control of gene expression, cell differentiation, and tissue morphogenesis has widespread application in regenerative medicine and the study of tissue development. In this work, we applied optogenetics to control cell differentiation and new tissue formation. Specifically, we engineered an optogenetic "on" switch that provides permanent transgene expression following a transient dose of blue light illumination. To demonstrate its utility in controlling cell differentiation and reprogramming, we incorporated an engineered form of the master myogenic factor MyoD into this system in multipotent cells...
August 9, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28774597/nintedanib-reduces-radiation-induced-microscopic-lung-fibrosis-but-this-cannot-be-monitored-by-ct-imaging-a-preclinical-study-with-a-high-precision-image-guided-irradiator
#17
Dirk De Ruysscher, Patrick Vincent Granton, Natasja Gaby Lieuwes, Stefan van Hoof, Lutz Wollin, Birgit Weynand, Anne-Marie Dingemans, Frank Verhaegen, Ludwig Dubois
BACKGROUND: Nintedanib has anti-fibrotic and anti-inflammatory activity and is approved for the treatment of idiopathic pulmonary fibrosis. The aim of this study was to noninvasively assess the efficacy of nintedanib in a mouse model of partial lung irradiation to prevent radiation-induced lung damage (RILD). METHODS: 266 C57BL/6 adult male mice were irradiated with a single radiation dose (0, 4, 8, 12, 16 or 20Gy) using parallel-opposed fields targeting the upper right lung using a precision image-guided small animal irradiator sparing heart and spine based on micro-CT images...
July 31, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28762187/the-choroid-plexus-is-a-key-cerebral-invasion-route-for-t-cells-after-stroke
#18
Gemma Llovera, Corinne Benakis, Gaby Enzmann, Ruiyao Cai, Thomas Arzberger, Alireza Ghasemigharagoz, Xiang Mao, Rainer Malik, Ivana Lazarevic, Sabine Liebscher, Ali Ertürk, Lilja Meissner, Denis Vivien, Christof Haffner, Nikolaus Plesnila, Joan Montaner, Britta Engelhardt, Arthur Liesz
Neuroinflammation contributes substantially to stroke pathophysiology. Cerebral invasion of peripheral leukocytes-particularly T cells-has been shown to be a key event promoting inflammatory tissue damage after stroke. While previous research has focused on the vascular invasion of T cells into the ischemic brain, the choroid plexus (ChP) as an alternative cerebral T-cell invasion route after stroke has not been investigated. We here report specific accumulation of T cells in the peri-infarct cortex and detection of T cells as the predominant population in the ipsilateral ChP in mice as well as in human post-stroke autopsy samples...
July 31, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28758372/metabolomic-profiling-of-long-term-weight-change-role-of-oxidative-stress-and-urate-levels-in-weight-gain
#19
Cristina Menni, Marie Migaud, Gabi Kastenmüller, Tess Pallister, Jonas Zierer, Annette Peters, Robert P Mohney, Tim D Spector, Vincenzo Bagnardi, Christian Gieger, Steve C Moore, Ana M Valdes
OBJECTIVE: To investigate the association between long-term weight change and blood metabolites. METHODS: Change in BMI over 8.6 ± 3.79 years was assessed in 3,176 females from the TwinsUK cohort (age range: 18.3-79.6, baseline BMI: 25.11 ± 4.35) measured for 280 metabolites at follow-up. Statistically significant metabolites (adjusting for covariates) were included in a multivariable least absolute shrinkage and selection operator (LASSO) model. Findings were replicated in the Cooperative Health Research in the Region of Augsburg (KORA) study (n = 1,760; age range: 25-70, baseline BMI: 27...
July 31, 2017: Obesity
https://www.readbyqxmd.com/read/28724814/comparison-of-intraocular-pressure-measurements-using-goldmann-tonometer-i-care-pro-tonopen-xl-and-schiotz-tonometer-in-patients-after-descemet-stripping-endothelial-keratoplasty
#20
Oded Ohana, David Varssano, Gabi Shemesh
PURPOSE: Post-Descemet stripping endothelial keratoplasty (DSEK) patients are prone for intraocular pressure (IOP) elevations and glaucoma. Corneal characteristics influence various IOP measuring devices in various ways. The aim of this study was to evaluate the agreement between four different IOP measuring devices: Goldmann applanation tonometer (GAT), I-care pro, Tonopen XL, and Schiotz tonometr in patients who underwent DSEK. METHODS: This was a prospective comparative study using a convenience cohort of post-DSEK patients with compact grafts...
July 2017: Indian Journal of Ophthalmology
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