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https://www.readbyqxmd.com/read/29765338/psychotherapeutic-treatment-for-anorexia-nervosa-a-systematic-review-and-network-meta-analysis
#1
REVIEW
Almut Zeeck, Beate Herpertz-Dahlmann, Hans-Christoph Friederich, Timo Brockmeyer, Gaby Resmark, Ulrich Hagenah, Stefan Ehrlich, Ulrich Cuntz, Stephan Zipfel, Armin Hartmann
Background: The aim of the study was a systematic review of studies evaluating psychotherapeutic treatment approaches in anorexia nervosa and to compare their efficacy. Weight gain was chosen as the primary outcome criterion. We also aimed to compare treatment effects according to service level (inpatient vs. outpatient) and age group (adolescents vs. adults). Methods: The data bases PubMed, Cochrane Library, Web of Science, Cinahl, and PsychInfo were used for a systematic literature search (until Feb 2017)...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29762071/vla-4-mediated-adhesion-of-melanoma-cells-on-the-blood-brain-barrier-is-the-critical-cue-for-melanoma-cell-intercalation-and-barrier-disruption
#2
Ana B García-Martín, Pascale Zwicky, Thomas Gruber, Christoph Matti, Federica Moalli, Jens V Stein, David Francisco, Gaby Enzmann, Mitchell P Levesque, Ekkehard Hewer, Ruth Lyck
Melanoma is the most aggressive skin cancer in humans. One severe complication is the formation of brain metastasis, which requires extravasation of melanoma cells across the tight blood-brain barrier (BBB). Previously, VLA-4 has been assigned a role for the adhesive interaction of melanoma cells with non-BBB endothelial cells. However, the role of melanoma VLA-4 for breaching the BBB remained unknown. In this study, we used a mouse in vitro BBB model and imaged the shear resistant arrest of melanoma cells on the BBB...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29755119/predictive-potential-of-tumour-stroma-ratio-on-benefit-from-adjuvant-bevacizumab-in-high-risk-stage-ii-and-stage-iii-colon-cancer
#3
Stéphanie M Zunder, Gabi W van Pelt, Hans J Gelderblom, Christoph Mancao, Hein Putter, Rob A Tollenaar, Wilma E Mesker
BACKGROUND: The tumour-stroma ratio (TSR) has proven to be an independent prognostic factor in colon cancer. METHODS: Haematoxylin eosin tissue slides of patients from the AVANT trial were microscopically scored for TSR and categorised as stroma -low or stroma -high. Scores were correlated to the primary and secondary endpoint disease-free survival (DFS) and overall survival (OS). RESULTS: Patients with stroma-high tumours (N = 339, 28%) had a significantly shorter DFS (p < 0...
May 14, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29744115/thrombotic-thrombocytopenic-purpura-possibly-triggered-by-graves-disease
#4
Saurabh D Chitnis, Tuoyo O Mene-Afejuku, Amandeep Aujla, Ahmed Shady, Gaby S Gil, Eder Hans Cativo, Andrea Popescu-Martinez
Thrombotic thrombocytopenic purpura (TTP) is a part of a spectrum of thrombotic microangiopathy syndromes which are mainly characterized by platelet aggregation causing microangiopathic hemolytic anemia, thrombocytopenia and microvascular occlusion. In literature, very few cases expressing a direct association between pre-existing Grave's disease and TTP have been described. A 37-year-old African-American woman with past medical history of Grave's disease and polysubstance abuse who presented with complaints of dyspnoea at rest and chest pain was diagnosed to have TTP on further evaluation...
October 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29736265/evaluation-of-a-clinical-implementation-of-a-respiratory-muscle-training-group-during-spinal-cord-injury-rehabilitation
#5
Anja M Raab, Jörg Krebs, Claudio Perret, Mirjam Pfister, Maria Hopman, Gabi Mueller
Study design: Retrospective cohort study. Objective: To evaluate the clinical implementation of a respiratory muscle training group during rehabilitation of individuals with spinal cord injury. Setting: Spinal cord injury rehabilitation center. Methods: Individuals with complete or incomplete lesions during inpatient rehabilitation, level C4-T12.Ten or more training sessions of either an inspiratory or a combined in- and expiratory muscle training were performed in a group setting with respiratory function measurements before and after the training period...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29734887/patient-autonomy-in-home-care-nurses-relational-practices-of-responsibility
#6
Gaby Jacobs
BACKGROUND: Over the last decade, new healthcare policies are transforming healthcare practices towards independent living and self-care of older people and people with a chronic disease or disability within the community. For professional caregivers in home care, such as nurses, this requires a shift from a caring attitude towards the promotion of patient autonomy. AIM: To explore how nurses in home care deal with the transformation towards fostering patient autonomy and self-care...
January 1, 2018: Nursing Ethics
https://www.readbyqxmd.com/read/29729511/evaluating-microwave-synthesized-silver-nanoparticles-from-silver-nitrate-with-life-cycle-assessment-techniques
#7
Adarsh Bafana, Shishir V Kumar, Sila Temizel-Sekeryan, Si Amar Dahoumane, Liv Haselbach, Clayton S Jeffryes
Silver Nanoparticles (AgNPs) are well known for applications in electronics and as antimicrobial agents because of their unique optical, electrical, cytotoxic and thermal properties. These nanoparticles can be synthesized via a wide variety of techniques; however, they require the use of hazardous solvents which have very high environmental impacts. Nanoscience researchers have attempted novel synthesis routes that reduce resource requirements and use benign chemicals, while maintaining control over their unique properties...
May 2, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29727907/pancreatic-beta-cell-proliferation-induced-by-estradiol-17%C3%AE-is-foxo1-dependent
#8
Sigal Shaklai, Meital Grafi-Cohen, Orli Sharon, Nadav Sagiv, Gabi Shefer, Dalia Somjen, Naftali Stern
Estradiol-17β (E2) and the Foxo1 transcription factor have each been implicated in the regulation of β-cell proliferation. Interaction between Foxo1and estrogen receptor alpha (ERα), effecting cell cycle, has been demonstrated in breast cancer cells, but has not been studied thus far in β-cells. Using human islets and the INS1-E β-cell line, this study investigated the contribution of Foxo1 to E2-mediated β-cell replication. Foxo1 expression was knocked down in INS1-E cells using siRNA and Foxo1 activity was inhibited in human islets with a specific Foxo1 inhibitor (AS1842856)...
May 4, 2018: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29723642/predictors-of-overnight-admission-after-minimally-invasive-hysterectomy-in-the-expert-setting
#9
Gaby Moawad, Paul Tyan, Victoria Vargas, Daniel Park, Hannah Young, Cherie Marfori
OBJECTIVE: To identify predictors of Same Day Discharge (SDD) overnight admission after laparoscopic and robot-assisted hysterectomy to improve preoperative counseling and patient optimization. DESIGN: A Single-center retrospective cohort study. (Canadian Task Force classification III). SETTING: Academic university hospital. PATIENTS: Patients undergoing straight-stick laparoscopic and robot-assisted hysterectomy by fellowship-trained minimally invasive gynecologic surgeons for benign indications INTERVENTIONS: Straight-stick laparoscopic and robot-assisted hysterectomy...
April 30, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29715571/length-of-thromboprophylaxis-in-patients-operated-for-a-high-grade-glioma-a-retrospective-study
#10
Joeky T Senders, Tom J Snijders, Max van Essen, Gaby M van Bentum, Tatjana Seute, Filip Y de Vos, Timothy R Smith, Pierre A Robe, Marike Ld Broekman
OBJECTIVE: High-grade gliomas are associated with venous thromboembolism (VTE). This retrospective study with a parallel cohort design investigates the influence of continuing prophylactic anticoagulation post-discharge on the rate of VTE and intracranial hemorrhage (ICH) in patients operated for a high-grade glioma. METHODS: Consecutive adult patients who underwent sub- or gross-total resection for a high-grade glioma at a single institution were included. Multivariable logistic regression analysis was used to investigate the association between the duration of thromboprophylaxis (dalteparin administered 21 versus 0-7 days) and the occurrence of VTE and ICH within 21 or 90 days after surgery, corrected for known risk factors...
April 28, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29694127/topological-phase-transitions-in-zinc-blende-semimetals-driven-exclusively-by-electronic-temperature
#11
Egor Trushin, Andreas Görling
We show that electronic phase transitions in zinc-blende semimetals with quadratic band touching (QBT) at the center of the Brillouin zone, like GaBi, InBi, or HgTe, can occur exclusively due to a change of the electronic temperature without the need to involve structural transformations or electron-phonon coupling. The commonly used Kohn-Sham density-functional methods based on local and semilocal density functionals employing the local density approximation (LDA) or generalized gradient approximations (GGAs), however, are not capable of describing such phenomena because they lack an intrinsic temperature dependence and account for temperature only via the occupation of bands, which essentially leads only to a shift of the Fermi level without changing the shape or topology of bands...
April 6, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29688643/-fmr1-premutation-carriers-are-they-really-asymptomatic
#12
REVIEW
Shai Elizur, Michal Berkenstadt, Liat Ries-Levavi, Noah Gruber, Orit Pinhas-Hamiel, Sharon Hassin-Baer, Annick Raas-Rothschild, Hila Raanani, Tali Cukierman-Yaffe, Raoul Orvieto, Yoram Cohen, Lidia Gabis
Fragile X Syndrome (FXS), the most common form of inherited mental retardation, is caused by a trinucleotide repeat expansion (CGG) in the 5'-untranslated region of the Fragile X Mental Retardation 1 (FMR1) gene located at Xq27.3. Patients with fragile X -related mental retardation, carry the full mutation CGG-repeat expansions (>200 CGG repeats), which are generally accompanied by hypermethylation of the promoter region, with the consequent transcriptional silencing of the FMR1 gene and absence of the encoded FMR1 protein (FMRP)...
April 2018: Harefuah
https://www.readbyqxmd.com/read/29665528/optimizing-photon-dose-and-frequency-to-enhance-lipid-productivity-of-thermophilic-algae-for-biofuel-production
#13
Said Abu-Ghosh, Zvy Dubinsky, Gabi Banet, David Iluz
The aim of this work was to examine the potential of the thermophilic green microalga Micractinium sp. to accumulate triacylglycerols (TAGs) and to develop a light strategy to increase TAG productivity in this alga. To this end, dense cultures of Micractinium sp. were grown at 37 °C under nitrogen (N) starvation and exposed to a light intensity of 1000 µmol photons m-2  s-1 of different light regimes. The highest per-biomass TAG-content and maximal volumetric productivities of TAG were displayed by the cultures grown under flashing light of 5 Hz with 50% duty cycle...
March 30, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29650975/author-correction-remodeling-of-the-actin-spectrin-membrane-associated-periodic-skeleton-growth-cone-collapse-and-f-actin-decrease-during-axonal-degeneration
#14
Nicolas Unsain, Martin D Bordenave, Gaby F Martinez, Sami Jalil, Catalina von Bilderling, Federico M Barabas, Luciano A Masullo, Aaron D Johnstone, Philip A Barker, Mariano Bisbal, Fernando D Stefani, Alfredo O Cáceres
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
April 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29649805/comparing-the-efficacy-of-cbasp-with-two-versions-of-cbt-for-depression-in-a-routine-care-center-a-randomized-clinical-trial
#15
Winfried Rief, Gabi Bleichhardt, Katharina Dannehl, Frank Euteneuer, Katrin Wambach
BACKGROUND: The cognitive-behavioral analysis system of psychotherapy (CBASP) was developed for the treatment of chronic, early-onset depression. However, it is unclear whether this approach can be recommended for depression in general (episodic and chronic), and no direct comparisons between CBASP with different versions of cognitive-behavioral therapy (CBT) exist. METHODS: A randomized controlled trial compared 3 treatment conditions (all lasting 16 sessions) with a waiting list group (WL): CBASP, CBT with a focus on physical exercise (CBT-E), and CBT with a focus on pleasurable, low-energy and mindful activities (CBT-M)...
April 12, 2018: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/29649071/predictors-of-early-scaffold-thrombosis-results-from-the-multicenter-prospective-german-austrian-absorb-registry
#16
Jochen Wöhrle, Holger M Nef, Christoph Naber, Stephan Achenbach, Thomas Riemer, Julinda Mehilli, Thomas Münzel, Steffen Schneider, Sinisa Markovic, Julia Seeger, Wolfgang Rottbauer, Thomas Pfannebecker, Gert Richardt, Ralf Zahn, Tommaso Gori, Johannes Kastner, Axel Schmermund, Christian W Hamm
BACKGROUND: In randomized clinical trials, the risk of thrombotic events with the absorb bioresorbable vascular scaffold (BVS) was significantly higher than with metallic drug-eluting stents. We evaluated predictors of scaffold thrombosis in the large-scale, multicenter German-Austrian ABSORB RegIstRy. METHODS AND RESULTS: 3178 patients with treatment of 4252 lesions using 5020 scaffolds were included. Follow-up rate at 6 months was 97.4%. Forty-five (1.42%) patients experienced definite/probable scaffold thrombosis during follow-up...
April 11, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29618101/impact-of-intranasal-oxytocin-on-interoceptive-accuracy-in-alcohol-users-an-attentional-mechanism
#17
Sophie Betka, Cassandra Gould Van Praag, Yannis Paloyelis, Rod Bond, Gaby Pfeifer, Henrique Sequeira, Theodora Duka, Hugo Critchley
Interoception, i.e. the perception and appraisal of internal bodily signals, is related to the phenomenon of craving, and is reportedly disrupted in alcohol use disorders. The hormone oxytocin influences afferent transmission of bodily signals and, through its potential modulation of craving, is proposed as a possible treatment for alcohol use disorders. However, oxytocin's impact on interoception in alcohol users remains unknown.Healthy alcohol users (N = 32) attended two laboratory sessions to perform tests of interoceptive ability (heartbeat tracking: attending to internal signals and, heartbeat discrimination: integrating internal and external signals) after intranasal administration of oxytocin or placebo...
March 28, 2018: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29608528/-analysis-of-craniofacial-remodeling-in-the-aging-midface-using-reconstructed-three-dimensional-models-in-paired-individuals
#18
Mihiran Karunanayake, Gaby Doumit
No abstract text is available yet for this article.
March 22, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29607530/systematic-review-drug-induced-liver-injury-alternative-causes-in-case-series-as-confounding-variables
#19
REVIEW
Rolf Teschke, Gaby Danan
AIMS: Drug-induced liver injury (DILI) is rare as compared to the worldwide frequent acute or chronic liver diseases. Therefore, patients included in series of suspected DILI are at high risk of not having DILI, whereby alternative causes may confound the DILI diagnosis. The aim of this review is to evaluate published case series of DILI for alternative causes. METHODS: Pertinent studies were identified using a computerized search of the Medline database for publications from 1993 through 30 October 2017...
April 1, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29602398/genome-wide-association-studies-of-metabolite-concentrations-mgwas-relevance-for-nephrology
#20
REVIEW
Anna Köttgen, Johannes Raffler, Peggy Sekula, Gabi Kastenmüller
Metabolites are small molecules that are intermediates or products of metabolism, many of which are freely filtered by the kidneys. In addition, the kidneys have a central role in metabolite anabolism and catabolism, as well as in active metabolite reabsorption and/or secretion during tubular passage. This review article illustrates how the coupling of genomics and metabolomics in genome-wide association analyses of metabolites can be used to illuminate mechanisms underlying human metabolism, with a special focus on insights relevant to nephrology...
March 2018: Seminars in Nephrology
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