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https://www.readbyqxmd.com/read/28925046/in-vivo-pharmacodynamic-and-pharmacokinetic-interactions-of-hibiscus-sabdariffa-calyces-extracts-with-simvastatin
#1
S J Showande, O M Adegbolagun, S I Igbinoba, T O Fakeye
WHAT IS KNOWN AND OBJECTIVES: Increasing number of patients use herbs with their medications. Such practice may result in beneficial or harmful herb-drug interactions. A recent survey reported that some participants co-administered Hibiscus sabdariffa, a widely used beverage, or tea, with their antihyperlipidaemic medications. This study therefore evaluated the effect of concomitant administration of Hibiscus sabdariffa calyces' extracts with simvastatin on hyperlipidaemia and pharmacokinetics of the drug in vivo...
September 18, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28924378/vasopressin-mediates-the-renal-damage-induced-by-limited-fructose-rehydration-in-recurrently-dehydrated-rats
#2
Fernando E García-Arroyo, Edilia Tapia, Mónica G Blas-Marron, Guillermo Gonzaga, Octaviano Silverio, Magdalena Cristóbal, Horacio Osorio, Abraham S Arellano-Buendía, Cecilia Zazueta, Omar Emiliano Aparicio-Trejo, Juan G Reyes-García, José Pedraza-Chaverri, Virgilia Soto, Carlos Roncal-Jiménez, Richard J Johnson, Laura G Sánchez-Lozada
Recurrent dehydration and heat stress cause chronic kidney damage in experimental animals. The injury is exacerbated by rehydration with fructose-containing beverages. Fructose may amplify dehydration-induced injury by directly stimulating vasopressin release and also by acting as a substrate for the aldose reductase-fructokinase pathway, as both of these systems are active during dehydration. The role of vasopressin in heat stress associated injury has not to date been explored. Here we show that the amplification of renal damage mediated by fructose in thermal dehydration is mediated by vasopressin...
2017: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/28923558/highly-selective-and-sensitive-sensor-based-on-an-organic-electrochemical-transistor-for-the-detection-of-ascorbic-acid
#3
Lijun Zhang, Guiheng Wang, Di Wu, Can Xiong, Lei Zheng, Yunsheng Ding, Hongbo Lu, Guobing Zhang, Longzhen Qiu
In this study, an organic electrochemical transistor sensor (OECT) with a molecularly imprinted polymer (MIP)-modified gate electrode was prepared for the detection of ascorbic acid (AA). The combination of the amplification function of an OECT and the selective specificity of MIPs afforded a highly sensitive, selective OECT sensor. Cyclic voltammetry and electrochemical impedance spectroscopy measurements were carried out to monitor the stepwise fabrication of the modified electrodes and the adsorption capacity of the MIP/Au electrodes...
September 7, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28923549/color-stability-of-lithium-disilicate-ceramics-after-aging-and-immersion-in-common-beverages
#4
Eleni-Sotiria Palla, Eleana Kontonasaki, Nikolaos Kantiranis, Lambrini Papadopoulou, Triantafyllia Zorba, Konstantinos M Paraskevopoulos, Petros Koidis
STATEMENT OF PROBLEM: The color of an esthetic restoration and its color stability are important for long-term success. However, the impact of common beverages on lithium disilicate ceramic is not well known. PURPOSE: The purpose of this in vitro study was to investigate color variations of lithium disilicate ceramics after thermal cycling (TC) and immersion in commonly consumed beverages. MATERIAL AND METHODS: A total of 288 specimens (1×10×10 mm) were fabricated from IPS e-max computer-aided design (CAD) (n=72), IPS e-max CERAM ([CER] n=72), IPS e-max Press with glazing ([PG] n=72), and IPS e-max Press without glazing ([PNG] n=72) according to the manufacturer's instructions...
September 16, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28922262/sugar-in-infants-children-and-adolescents-a-position-paper-of-the-european-society-for-paediatric-gastroenterology-hepatology-and-nutrition-committee-on-nutrition
#5
Nataša Fidler Mis, Christian Braegger, Jiri Bronsky, Cristina Campoy, Magnus Domellöf, Nicholas D Embleton, Iva Hojsak, Jessie Hulst, Flavia Indrio, Alexandre Lapillonne, Walter Mihatsch, Christian Molgaard, Rakesh Vora, Mary Fewtrell
The consumption of sugars, particularly sugar-sweetened beverages (SSBs; beverages or drinks that contain added caloric sweeteners (i.e. sucrose, high-fructose corn syrup, fruit-juice concentrates), in European children and adolescents exceeds current recommendations. This is of concern because there is no nutritional requirement for free sugars, and infants have an innate preference for sweet taste, which may be modified and reinforced by pre- and postnatal exposures. Sugar containing beverages/free sugars increase the risk for overweight/obesity and dental caries, can result in poor nutrient supply and reduced dietary diversity and may be associated with increased risk of type 2 diabetes mellitus, cardiovascular risk, and other health effects...
September 16, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28922065/a-study-examining-the-effect-of-a-short-bout-of-postprandial-walking-on-the-glycemic-effect-of-a-meal-type-1-diabetes
#6
Samantha L Hinojosa, Cynthia J Heiss
OBJECTIVE: The purpose of this pilot study was to determine whether 15 minutes of postprandial walking has an effect on the glycemic response to a breakfast beverage in individuals with type 1 diabetes (T1DM). METHODS: Seven participants, aged 22.3 ± 4.3 years, with T1DM using intensive insulin therapy completed 2 days of data collection. On day 1, participants measured baseline fasting blood glucose (BG) with a glucometer, consumed an 8-ounce Boost® beverage (41 grams carbohydrate), administered a bolus of insulin according to the carbohydrate load and fasting BG, and sat quietly, repeating BG measurements 15, 30, 60, 90, and 120 minutes after consumption...
September 18, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28921988/interaction-of-food-additives-with-intestinal-efflux-transporters
#7
Noora Sjöstedt, Feng Deng, Oskari Rauvala, Tuomas Tepponen, Heidi Kidron
Breast cancer resistance protein (BCRP), multidrug resistance associated protein 2 (MRP2) and P-glycoprotein (P-gp) are ABC transporters that are expressed in the intestine, where they are involved in the efflux of many drugs from enterocytes back into the intestinal lumen. The inhibition of BCRP, MRP2 and P-gp can result in the enhanced absorption and exposure of substrate drugs. Food additives are widely used by the food industry to improve the stability, flavor and consistency of food products. Although they are considered safe for consumption, their interactions with intestinal transporters are poorly characterized...
September 18, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28919252/mutation-in-the-peroxin-coding-gene-pex22-contributing-to-high-malate-production-in-saccharomyces-cerevisiae
#8
Hiroaki Negoro, Mitsuru Sakamoto, Atsushi Kotaka, Kengo Matsumura, Yoji Hata
Saccharomyces cerevisiae produces organic acids such as succinate, acetate, and malate during alcoholic fermentation. Since malate contributes to the pleasant taste of sake (a Japanese alcoholic beverage), various methods for breeding high-malate-producing yeast strains have been developed. Here, a high-malate-producing yeast strain F-701H was isolated. This mutant was sensitive to dimethyl succinate (DMS) and harbored a nonsense mutation in the peroxin gene PEX22, which was identified as the cause of high malate production by comparative genome analysis...
September 14, 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28919036/blends-of-non-caloric-sweeteners-saccharin-and-cyclamate-show-reduced-off-taste-due-to-tas2r-bitter-receptor-inhibition
#9
Maik Behrens, Kristina Blank, Wolfgang Meyerhof
Non-caloric sweeteners are widely used for the formulation of calorie-reduced beverages for health-conscious consumers. However, disadvantages such as undesired off-tastes limit the use of non-nutritive sweeteners. Therefore, the food industry is constantly searching for novel sweeteners and frequently resorts to using blends combining non-caloric sweeteners in a single formulation. The earliest blend allowing higher sweetness levels with reduced bitter off-taste combined saccharin with cyclamate. However, the mechanism by which sweetener blends become superior to single compounds remained obscure...
August 23, 2017: Cell Chemical Biology
https://www.readbyqxmd.com/read/28918230/biosensing-methods-for-determination-of-triglycerides-a-review
#10
REVIEW
C S Pundir, Vinay Narwal
Triglycerides (TGs) are the major transporters of dietary fats throughout the bloodstream. Besides transporting fat, TGs also act as stored fat in adipose tissue, which is utilized during insufficient carbohydrates supply. TG level is below 150mg/dL in healthy persons. Elevated TGs level in blood over 500mg/dL is a biomarker for cardiovascular diseases, Alzheimer disease, pancreatitis and diabetes. Numerous methods are accessible for recognition of TGs, among them, most are cumbersome, time-consuming, require sample pre-treatment, high cost instrumental set-up and experienced personnel to operate...
September 9, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28917621/effects-of-latino-children-on-their-mothers-dietary-intake-and-dietary-behaviors-the-role-of-children-s-acculturation-and-the-mother-child-acculturation-gap
#11
Sandra H Soto, Elva M Arredondo, Bess Marcus, Holly B Shakya, Scott Roesch, Guadalupe X Ayala
RATIONALE: Research shows that acculturation is important to Latinas' dietary intake and related behaviors. Although evidence suggests children may also play a role, it remains unclear whether children's acculturation is related to mothers' dietary intake/behaviors. OBJECTIVES: We examined the relationship between Latino children's acculturation and mothers' dietary intake/behaviors. We also examined the mother-child acculturation gap to identify dyad characteristics associated with mothers' diet...
September 5, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28917262/determination-of-several-element-levels-in-hardaliye-beverages-using-flame-atomic-absorption-spectrometry-after-ultrasound-probe-extraction
#12
Dilek Bakircioglu, Nukte Topraksever, Yasemin Bakircioglu Kurtulus
In the present study, concentrations of calcium (Ca), copper (Cu), magnesium (Mg), manganese (Mn), sodium (Na), and zinc (Zn) in hardaliye samples produced in Turkey were determined by flame atomic absorption spectrometry after ultrasound probe extraction (UPE), microwave-assisted extraction (MAE), and wet extraction procedures. At present, there is limited work in the literature on UPE for the determination of trace elements in beverage samples. Our single-correlation analysis showed that the elements studied with the UPE method in hardaliye were strongly correlated with the MAE procedure...
September 1, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28917240/snack-and-beverage-consumption-and-preferences-in-a-sample-of-chinese-children-are-they-influenced-by-advertising
#13
Peng Liu, Yang Yu, Lesley King, Mu Li
BACKGROUND AND OBJECTIVES: The consumption of unhealthy snack and beverages can lead to childhood obesity, which has become a major concern globally. Television food advertisements may influence children's snack and beverages preferences. This article aims to explore children's snack and beverage consumption habits; examine the extent of television advertising for non-core (energy-dense, nutrient poor) snack and beverages; and assess the influence of television advertising on children's snack and beverages preferences in Harbin, China...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28917070/consumption-and-correlates-of-sweet-foods-carbonated-beverages-and-energy-drinks-among-primary-school-children-in-saudi-arabia
#14
Ali Saad R Alsubaie
To assess the consumption of sweets, carbonated beverages, and energy drinks along with their correlates among primary school children.  Methods: A total of 725 children (7-12 years old) were randomly recruited from 10 elementary schools from Al-Baha city, Saudi Arabia in 2013, using a multi-stage stratified sampling technique and pre-tested validated questionnaire.  Results: Approximately 26.1% of children reported consuming sweets on daily basis, and 63.4% consumed sweets occasionally during the week...
October 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28916568/perspective-the-paradox-in-dietary-advanced-glycation-end-products-research-the-source-of-the-serum-and-urinary-advanced-glycation-end-products-is-the-intestines-not-the-food
#15
Luanne R DeChristopher
Inconsistent research results have impeded our understanding of the degree to which dietary advanced glycation end products (dAGEs) contribute to chronic disease. Early research suggested that Western-style fast foods, including grilled and broiled meats and French fries, contain high levels of proinflammatory advanced glycation end products (AGEs). However, recent studies with state-of-the-art ultraperformance LC-tandem mass spectrometry (UPLC-MS) found that there is no evidence that these foods have elevated levels of dAGEs relative to other foods...
September 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28915966/use-of-anthropogenic-nitrogen-fertilizers-in-agriculture-is-associated-with-per-capita-ethanol-consumption
#16
Keith Fluegge, Kyle Fluegge
It has previously been demonstrated that emissions of the agricultural pollutant, nitrous oxide (N2O), may be a confounder to the relationship between herbicide use and psychiatric impairments, including ADHD. This report attempts to extend this hypothesis by testing whether annual use of anthropogenic nitrogen-based fertilizers in U.S. agriculture (thought to be the most reliable indicator of environmental N2O emissions) is associated with per capita ethanol consumption patterns, a behavior often comorbid with ADHD...
September 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28915844/financial-incentives-and-purchase-restrictions-in-a-food-benefit-program-affect-the-types-of-foods-and-beverages-purchased-results-from-a-randomized-trial
#17
Simone A French, Sarah A Rydell, Nathan R Mitchell, J Michael Oakes, Brian Elbel, Lisa Harnack
BACKGROUND: This research evaluated the effects of financial incentives and purchase restrictions on food purchasing in a food benefit program for low income people. METHODS: Participants (n=279) were randomized to groups: 1) Incentive- 30% financial incentive for fruits and vegetables purchased with food benefits; 2) Restriction- no purchase of sugar-sweetened beverages, sweet baked goods, or candies with food benefits; 3) Incentive plus Restriction; or 4) Control- no incentive or restrictions...
September 16, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28914786/baseline-and-estimated-trends-of-sodium-availability-and-food-sources-in-the-costa-rican-population-during-2004-2005-and-2012-2013
#18
Adriana Blanco-Metzler, Rafael Moreira Claro, Katrina Heredia-Blonval, Ivannia Caravaca Rodríguez, María de Los A Montero-Campos, Branka Legetic, Mary R L'Abbe
In 2012, Costa Rica launched a program to reduce salt and sodium consumption to prevent cardiovascular disease and associated risk factors, but little was known about the level of sodium consumption or its sources. Our aim was to estimate the magnitude and time trends of sodium consumption (based on food and beverage acquisitions) in Costa Rica. Data from the National Household Income and Expenditure Surveys carried out in 2004-2005 (n = 4231) and 2012-2013 (n = 5705) were used. Records of food purchases for household consumption were converted into sodium and energy using food composition tables...
September 15, 2017: Nutrients
https://www.readbyqxmd.com/read/28914764/antioxidant-activity-of-spices-and-their-impact-on-human-health-a-review
#19
REVIEW
Alexander Yashin, Yakov Yashin, Xiaoyan Xia, Boris Nemzer
Antioxidants are substances that prevent oxidation of other compounds or neutralize free radicals. Spices and herbs are rich sources of antioxidants. They have been used in food and beverages to enhance flavor, aroma and color. Due to their excellent antioxidant activity, spices and herbs have also been used to treat some diseases. In this review article, the chemical composition and antioxidant activity of spices and culinary herbs are presented. The content of flavonoids and total polyphenols in different spices and herbs are summarized...
September 15, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28913969/spray-inlet-microwave-plasma-torch-ionization-tandem-mass-spectrometry-for-the-direct-detection-of-drug-samples-in-liquid-solutions
#20
Meng Miao, Gaosheng Zhao, Yaliang Wang, Li Xu, Junguo Dong, Ping Cheng
RATIONALE: Drug abuse or dependence results in a series of social problems, including crime and traffic accidents. Spray inlet microwave plasma torch tandem mass spectrometry (MPT-MS/MS) was developed and used for the direct detection of such drugs in liquid solutions. METHODS: Drug sample solutions were directly sprayed into the flame of MPT by a sampling pump and the ions produced by Penning ionization and ion-molecule reactions were guided into a QTOF tandem mass spectrometer for mass analysis...
September 14, 2017: Rapid Communications in Mass Spectrometry: RCM
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