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https://www.readbyqxmd.com/read/28426110/closing-the-gap-in-travel-medicine-reframing-research-questions-for-a-new-era
#1
Lin H Chen, Karin Leder, Mary E Wilson
Background: Travel medicine needs are changing. New patterns of travel, including greater travel by individuals from emerging economies with different values in costs, risks and benefits, must be considered. This review aims to (1) highlight selected studies that have been published that address previously identified gaps in knowledge; (2) propose possible ways to consider questions regarding travel medicine practice for travelers from emerging economies, underscoring priorities for research focusing on these important populations; (3) highlight potential deficiencies in relevance of current international guidelines as they pertain to travelers from emerging economies; (4) frame research questions for travelers from emerging economies and (5) consider roles for ISTM in closing the gap...
July 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28424823/-coma-in-the-emergency-room
#2
M Braun, C J Ploner, T Lindner, M Möckel, W U Schmidt
Coma of unknown origin (CUO) is a frequent unspecific emergency symptom associated with a high mortality. A fast diagnostic work-up is essential given the wide spectrum of underlying diagnoses that are made up of approximately 50% primary central nervous system (CNS) pathologies and approximately 50% extracerebral, almost exclusively internal medical causes. Despite the high mortality associated with this symptom, there are currently no generally accepted management guidelines for adult patients presenting with CUO...
April 19, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28412804/-status-and-analysis-of-off-label-drug-use-in-department-of-ophthalmology
#3
F R Han, H Y Zhao, L Li, J W Wang
Objective: To investigate and analyze the status of off-label drug use in department of ophthalmology of Beijing Tongren Hospital. Methods: Cross-sectional study. Prescription evaluation, off-label drug use application and temporary medicine purchase application were collected from January 2013 to March 2015. The off-label use of medication in department of ophthalmology were filtered out and analyzed according to the category of medications, the category of the off-label use of medication and the strength of evidence for the off-label use of medication...
April 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28406489/consensus-recommendation-for-a-diagnostic-guideline-for-acid-sphingomyelinase-deficiency
#4
Margaret M McGovern, Carlo Dionisi-Vici, Roberto Giugliani, Paul Hwu, Olivier Lidove, Zoltan Lukacs, Karl Eugen Mengel, Pramod K Mistry, Edward H Schuchman, Melissa P Wasserstein
Disclaimer:This diagnostic guideline is intended as an educational resource and represents the opinions of the authors, and is not representative of recommendations or policy of the American College of Medical Genetics and Genomics (ACMG). The information should be considered a consensus based on expert opinion, as more comprehensive levels of evidence were not available in the literature in all cases. BACKGROUND: Acid sphingomyelinase deficiency (ASMD) is a rare, progressive, and often fatal lysosomal storage disease...
April 13, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28395092/travellers-diarrhoea-a-survey-of-practice
#5
Christian M McGrath, Karin Leder
Background.: Travellers' diarrhoea (TD) is a common problem, affecting millions of tourists each year and creating a large economic burden. Risk factors for TD are known and guidelines exist to assist practitioners in advising travellers on how to prevent and treat TD. However, data are lacking regarding actual prescribing practices or approaches used in TD management. This study aims to establish a baseline which identifies uniformities and diversities in practice. Methods...
March 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28394965/-ethical-conflicts-in-the-authorship-of-scientific-papers
#6
Astrid von Oetinger, Kabir P Sadarangani, Sofía P Salas
The frequency of conflicts about authorship of publications has increased along with the increase in the number of people involved in scientific work. Some of the factors that strongly influence the generation of conflicts and malpractices in authorship definition of scientific publications are the pressure of academia, economic incentives from the pharmaceutical industry in the field of biomedicine and authors’ wishes and expectations of recognition, among other factors. The article analyzes this problem, increasingly common in the field of medicine and related areas...
November 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28392735/evaluating-performance-in-sweat-testing-in-medical-biochemistry-laboratories-in-croatia
#7
Merica Aralica, Jasna Lenicek Krleza
INTRODUCTION: Sweat test has a diagnostic role in evaluation of cystic fibrosis. Its performance includes sweat stimulation, collection and analysis. All listed may be sources of inconsistencies in everyday practice. The aim of this study was an evaluation of external quality assessment (EQA) of sweat chloride measurement including sweat test performance in medical biochemistry laboratories in Croatia. MATERIALS AND METHODS: EQA for sweat chloride measurement was provided by Croatian Centre for Quality Assessment in Laboratory Medicine (CROQALM) in five consecutive exercises to medical biochemistry laboratories (MBL) that offered sweat testing...
February 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28392723/the-role-of-eqa-in-harmonization-in-laboratory-medicine-a-global-effort
#8
REVIEW
Graham R D Jones
There are many activities currently being undertaken in the field of laboratory medicine under the broad heading of "harmonization". These include traceability of results to international reference standards, processes to align results from assays where traceability has not been achieved (analytical harmonization) and international or national clinical guidelines based on studies from many parts of the world. Many of these issues are global in nature, with clinical evidence derived from studies performed in all parts of the world and multinational diagnostic companies providing assays worldwide...
February 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28385575/intersecting-worlds-of-transfusion-and-transplantation-medicine-an-international-symposium-organized-by-the-canadian-blood-services-centre-for-innovation
#9
REVIEW
Kendra M Hodgkinson, Jeffrey Kiernan, Andrew W Shih, Ziad Solh, William P Sheffield, Nicolas Pineault
The principal theme of the symposium was centered on how the world of regenerative medicine intersects with that of transfusion medicine, with a particular focus on hematopoietic stem cells (HSCs) and stem cell therapies. The symposium highlighted several exciting developments and identified areas where additional research is needed. A revised map of human hematopoietic hierarchy was presented based on the functional and phenotypic analysis of thousands of single stem and progenitor cells from adult bone marrow and fetal liver...
March 22, 2017: Transfusion Medicine Reviews
https://www.readbyqxmd.com/read/28385463/clinical-and-social-barriers-to-antimicrobial-stewardship-in-pulmonary-medicine-a-qualitative-study
#10
Jennifer K Broom, Alex F Broom, Emma R Kirby, Alexandra F Gibson, Jeffrey J Post
BACKGROUND: The treatment of pulmonary infections is one of the largest indications for antibiotics in human health care, offering significant potential for antibiotic optimization internationally. This study explores the perspectives of pulmonary clinicians on antibiotic use in hospital pulmonary infections. METHODS: Twenty-eight pulmonary doctors and nurses from 2 hospitals participated in semi-structured interviews focusing on their experiences of antibiotic use...
April 3, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28384684/an-international-collaborative-standardizing-a-comprehensive-patient-centered-outcomes-measurement-set-for-colorectal-cancer
#11
Jessica A Zerillo, Maartje G Schouwenburg, Annelotte C M van Bommel, Caleb Stowell, Jacob Lippa, Donna Bauer, Ann M Berger, Gilles Boland, Josep M Borras, Mary K Buss, Robert Cima, Eric Van Cutsem, Eino B van Duyn, Samuel R G Finlayson, Skye Hung-Chun Cheng, Corinna Langelotz, John Lloyd, Andrew C Lynch, Harvey J Mamon, Pamela K McAllister, Bruce D Minsky, Joanne Ngeow, Muhammad R Abu Hassan, Kim Ryan, Veena Shankaran, Melissa P Upton, John Zalcberg, Cornelis J van de Velde, Rob Tollenaar
Importance: Global health systems are shifting toward value-based care in an effort to drive better outcomes in the setting of rising health care costs. This shift requires a common definition of value, starting with the outcomes that matter most to patients. Objective: The International Consortium for Health Outcomes Measurement (ICHOM), a nonprofit initiative, was formed to define standard sets of outcomes by medical condition. In this article, we report the efforts of ICHOM's working group in colorectal cancer...
April 6, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28378737/-all-russian-consensus-on-diagnosis-and-treatment-of-celiac-disease-in-children-and-adults
#12
A I Parfenov, S V Bykova, E A Sabel'nikova, I V Maev, A A Baranov, I G Bakulin, L M Krums, S V Bel'mer, T E Borovik, I N Zakharova, Yu A Dmitrieva, E A Roslavtseva, E A Kornienko, A I Khavkin, A S Potapov, M O Revnova, Yu G Mukhina, P L Shcherbakov, E D Fedorov, E A Belousova, I L Khalif, S G Khomeriki, D L Rotin, N G Vorob'eva, A V Pivnik, R B Gudkova, V V Chernin, N V Vokhmyanina, T V Pukhlikova, D A Degtyarev, I V Damulin, A M Mkrtumyan, G S Dzhulai, N K Tetruashvili, A Yu Baranovsky, L I Nazarenko, A G Kharitonov, I D Loranskaya, R G Saifutdinov, M A Livzan, D A Abramov, M F Osipenko, L V Oreshko, E I Tkachenko, S I Sitkin, L I Efremov
The paper presents the All-Russian consensus on the diagnosis and treatment of celiac disease in children and adults, which has been elaborated by leading experts, such as gastroenterologists and pediatricians of Russia on the basis of the existing Russian and international guidelines. The consensus approved at the 42nd Annual Scientific Session of the Central Research Institute of Gastroenterology on Principles of Evidence-Based Medicine into Clinical Practice (March 2-3, 2016). The consensus is intended for practitioners engaged in the management and treatment of patients with celiac disease...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28378728/-prevalence-of-external-respiratory-dysfunction-in-young-people
#13
N A Koval'kova, N Yu Travnikova, Yu I Ragino, M I Voevoda
AIM: To investigate the prevalence of impaired external respiration function (ERF) in young Novosibirsk dwellers. SUBJECTS AND METHODS: A cross-sectional population-based survey in one of the typical districts of Novosibirsk was conducted at the Research Institute of Internal and Preventive Medicine in 2013-2015. ERF was examined by spirometry in accordance with the guidelines. The best indicators of forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and FEV1/FVC ratio were selected and three reproducible attempts were made to evaluate ERF...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28377393/does-a-brief-behavioural-intervention-delivered-by-paediatricians-or-psychologists-improve-sleep-problems-for-children-with-adhd-protocol-for-a-cluster-randomised-translational-trial
#14
E Sciberras, M Mulraney, H Heussler, N Rinehart, T Schuster, L Gold, N Hayes, H Hiscock
INTRODUCTION: Up to 70% of children with attention-deficit/hyperactivity disorder (ADHD) experience sleep problems. We have demonstrated the efficacy of a brief behavioural intervention for children with ADHD in a large randomised controlled trial (RCT) and now aim to examine whether this intervention is effective in real-life clinical settings when delivered by paediatricians or psychologists. We will also assess the cost-effectiveness of the intervention. METHODS AND ANALYSIS: Children aged 5-12 years with ADHD (n=320) are being recruited for this translational cluster RCT through paediatrician practices in Victoria and Queensland, Australia...
April 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28377294/a-survey-on-general-and-temperature-management-of-post-cardiac-arrest-patients-in-large-teaching-and-university-hospitals-in-14-european-countries-the-spame-trial-results
#15
Christian Storm, J Nee, Kjetil Sunde, Michael Holzer, Pia Hubner, Fabio Silvio Taccone, Hans Friberg, Esteban Lopez-de-Sa, Alain Cariou, Joerg C Schefold, Giuseppe Ristagno, Marko Noc, Dirk W Donker, Janusz Andres, Pawel Krawczyk, Markus B Skrifvars, James Penketh, Alexander Krannich, Michael Fries
INTRODUCTION: International guidelines recommend a bundle of care, including targeted temperature management (TTM), in post cardiac arrest survivors. Aside from a few small surveys in different European countries, adherence to the European Resuscitation Council (ERC) and European Society of Intensive Care Medicine (ESICM) recommendations are unknown. METHODS: This international European telephone survey was conducted to provide an overview of current clinical practice of post cardiac arrest management with a main focus on TTM...
April 2, 2017: Resuscitation
https://www.readbyqxmd.com/read/28376904/academic-research-productivity-of-post-graduate-students-at-makerere-university-college-of-health-sciences-uganda-from-1996-to-2010-a-retrospective-review
#16
E A Obuku, J N Lavis, A Kinengyere, D K Mafigiri, F Sengooba, C Karamagi, N K Sewankambo
BACKGROUND: Research is a core business of universities globally, and is crucial in the scientific process as a precursor for knowledge uptake and use. We aimed to assess the academic productivity of post-graduate students in a university located in a low-income country. METHODS: This is an observational retrospective documentary analysis using hand searching archives, Google Scholar and PubMed electronic databases. The setting is Makerere University College of Health Sciences, Uganda...
April 4, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28370388/quality-of-widely-available-video-instructional-materials-for-point-of-care-ultrasound-guided-procedure-training-in-internal-medicine
#17
Aditi Khandelwal, Luke A Devine, Mirek Otremba
OBJECTIVES: Many instructional materials for point-of-care ultrasound (US)-guided procedures exist; however, their quality is unknown. This study assessed widely available educational videos for point-of-care US-guided procedures relevant to internal medicine: central venous catheterization, thoracentesis, and paracentesis. METHODS: We searched Ovid MEDLINE, YouTube, and Google to identify videos for point-of-care US-guided paracentesis, thoracentesis, and central venous catheterization...
April 3, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28367005/a-multidisciplinary-approach-to-improve-the-quality-of-care-for-patients-with-fragility-fractures
#18
Laura C Lamb, Stephanie C Montgomery, Brian Wong Won, Siobhan Harder, Jeffrey Meter, James M Feeney
BACKGROUND: Fragility fractures have become a worldwide epidemic associated with significant morbidity and mortality. As the world population ages, the number of patients that experience these fractures is also expected to rise. A multidisciplinary team was assembled that was coordinated by the Acute Inpatient Medical Service and included orthopedic surgeons, geriatricians, anesthesiologists, cardiologists, nurses, trauma surgeons, emergency medicine physicians, physiatrists, and physical therapists...
June 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28358779/early-identification-and-treatment-of-osteoporosis-in-a-rural-internal-medicine-clinic-a-quasi-experimental-approach-toquality-improvement
#19
J J Jones, Kristina Henry
Osteoporosis affects more than 44 million individuals in the United States annually while disease management continues to fall short of the recommended guidelines. This study institutes a practice change for osteoporosis/osteopenia screening and treatment founded on current evidence-based guidelines. A retrospective chart review was evaluated for current trends in the identification and treatment of osteoporosis/osteopenia in female patients older than 65 years. Data were then compared with identical data collected after implementing an evidence-based osteoporosis guideline tool...
March 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/28357835/identification-of-world-health-organisation-ship-s-medicine-chest-contents-by-anatomical-therapeutic-chemical-atc-classification-codes
#20
Seyed Khorsow Tayebati, Giulio Nittari, Syed Sarosh Mahdi, Nicholas Ioannidis, Fabio Sibilio, Francesco Amenta
BACKGROUND: Ships should carry mandatory given amounts of medicinal products and basic first aid items, collectively known as the ship's medicine chest. Type and quantities of these products/items are suggested by the World Health Organisation (WHO) and regulated by individual flag states. In countries that lack national legislation, it is assumed that ships should follow WHO indications. An objective difficulty mainly involving vessels of international long-haul routes could be to recognise medicinal compounds obtained in other countries for replacing products used or expired...
2017: International Maritime Health
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