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https://www.readbyqxmd.com/read/28133064/-treatment-experience-with-sorafenib-for-lung-metastases-of-hepatocellular-carcinoma-complicated-with-interstitial-pneumonia
#1
Takashi Shuto, Masahiro Murakami, Junzo Shimizu, Chikato Koga, Akinobu Yasuyama, Tae Matsumura, Chizu Kameda, Ryohei Kawabata, Masaki Hirota, Masato Yoshikawa, Shingo Noura, Junichi Hasegawa
A 74-year-old man was diagnosed with hepatocellular carcinoma(HCC; S4/8)and underwent anterior segment resection of the liver in 2015. He was hospitalized with a wound infection 2 months after surgery. On the 8th hospital day he complained of respiratory discomfort. A CT showed multiple lung metastases and a ground-glass appearance in both lungs. We diagnosed interstitial pneumonia with metastatic lung tumors. Steroid therapy was performed for the interstitial pneumo- nia(prednisolone 1,000mg/day×3 days), and sorafenib therapy was initiated for the metastatic lung cancer(starting from 200mg/day to 800mg/day)...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28126400/port-site-metastases-a-survey-of-the-society-of-gynecologic-oncology-and-commentary-on-the-clinical-workup-and-management-of-port-site-metastases
#2
Caitlin D Baptiste, Alexandre Buckley de Meritens, Nathaniel L Jones, Sudeshna Chatterjee Paer, Ana I Tergas, June Y Hou, Jason D Wright, William M Burke
STUDY OBJECTIVE: Laparoscopic port site metastases (PSM) have an incidence of 0.5-2%. The management of an isolated PSM (iPSM), without evidence of recurrence elsewhere, remains unclear. The aim of this study was to elucidate practices regarding iPSMs. DESIGN: A 23-item survey was created using commercially available survey software. Over the course of January 2016 the survey was e-mailed to the members of the Society of Gynecologic Oncology with two follow up reminder e-mails...
January 23, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28090784/effect-of-resveratrol-and-tetracycline-on-the-subacute-paraquat-toxicity-in-mice
#3
R M Satpute, P P Pawar, S Puttewar, S D Sawale, P D Ambhore
Paraquat (PQ) is a nonselective bipyridyl herbicide widely used in agriculture to control weeds, but its accidental, occupational, or intentional exposure in humans is known to cause pneumo- and neurotoxicity which may proves fatal. Oxidative stress is reported as an underlined mechanism of PQ-induced toxicity in alveolar cells, neurons, and astroglia. PQ generates superoxides both through electron transport reaction (ETC) with nicotinamide adenine dinucleotide-dependent oxidoreductase and by the redox cycling via reaction with molecular oxygen...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28043271/-autocorrelation-analysis-of-pneumoconiosis-in-china
#4
P Xiao, D Wang, X J Zhu
Objective: Using spatial autocorrelation analysis to study spatial distribution characteristics of pneumoconiosis in China. Methods: The incidence of pneumoconiosis of each province from 2009 to 2013 was calculated by reported data of pneumoconiosis and the number of employment in mining and manufacturing of each province from Chinese statistical yearbook. The global and local spatial autocorrelation analysis was im-plemented by global and local's Moran's I index respectively. Results: A total of 112 066 new cases of pneumo-coniosis were reported from 2009 to 2013 in China, Global Moran's I from 2009 to 2013 was -0...
November 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28018811/management-of-postintubational-tracheal-injury-by-endoscopic-stent-placement-case-report-and-review-of-the-literature
#5
Christian Geltner, Rudolf Likar, Klaus Hausegger, Markus Rauter
Endobronchial stent placement is a novel therapy for treatment of iatrogenic tracheal tears. A review of the available literature shows surgery and long-term intubation being the established treatment strategy. We describe the case of a 64-year-old woman with a tracheal rupture following endotracheal intubation for routine surgery. Pneumo-mediastinum and chest pain were the predominant symptoms. She was treated with a covered self-expandable metal stent that closed the tear and led to immediate symptom relief...
December 2016: Thoracic and Cardiovascular Surgeon Reports
https://www.readbyqxmd.com/read/27913372/an-ehealth-project-on-invasive-pneumococcal-disease-comprehensive-evaluation-of-a-promotional-campaign
#6
Donatella Panatto, Alexander Domnich, Roberto Gasparini, Paolo Bonanni, Giancarlo Icardi, Daniela Amicizia, Lucia Arata, Stefano Carozzo, Alessio Signori, Angela Bechini, Sara Boccalini
BACKGROUND: The recently launched Pneumo Rischio eHealth project, which consists of an app, a website, and social networking activity, is aimed at increasing public awareness of invasive pneumococcal disease (IPD). The launch of this project was prompted by the inadequate awareness of IPD among both laypeople and health care workers, the heavy socioeconomic burden of IPD, and the far from optimal vaccination coverage in Italy, despite the availability of safe and effective vaccines. OBJECTIVE: The objectives of our study were to analyze trends in Pneumo Rischio usage before and after a promotional campaign, to characterize its end users, and to assess its user-rated quality...
December 2, 2016: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/27895641/pneumococcal-polysaccharide-vaccination-elicits-igg-anti-a-b-blood-group-antibodies-in-healthy-individuals-and-patients-with-type-i-diabetes-mellitus
#7
Wendelin Wolfram, Kai M T Sauerwein, Christoph J Binder, Nicole Eibl-Musil, Hermann M Wolf, Michael B Fischer
HYPOTHESIS: Blood group antibodies are natural antibodies that develop early in life in response to cross-reactive environmental antigens in the absence of antigen encounter. Even later in life structural similarities in saccharide composition between environmental antigens such as bacterial polysaccharides and blood group A/B antigens could lead to changes in serum levels, IgM/IgG isotype, and affinity maturation of blood group anti-A/B antibodies. We addressed the question whether immunization with pneumococcal polysaccharide (PnP) vaccine Pneumo 23 Vaccine "Pasteur Merieux" (Pn23) could have such an effect in patients with type I diabetes mellitus (DM I), an autoimmune disease where an aberrant immune response to microbial antigens likely plays a role...
2016: Frontiers in Immunology
https://www.readbyqxmd.com/read/27800112/-pulmonary-tuberculosis-among-hospitalized-patients-in-brazzaville-impact-of-late-diagnosis-of-hiv-infection-on-radiographic-abnormalities
#8
Esthel Lee Presley Bemba, Régis Gothard Bopaka, Régis Moyikoua, Rolland Ossibi-Ibara, Norela Bibiane Ebenga-Somboko, Syn Nerval Toungou, Paunel God'hervé Matondot, Boris Kevin Ossale-Abacka, Franck Hardain Okemba-Okombi, Joseph Mboussa
The aim was to describing the different radiographic features of pulmonary tuberculosis according to the degree of immunosuppression in HIV patients. We report a retrospective study of 80 untreated HIV-positive patients with pulmonary tuberculosis hospitalized in the Pneumo-Phthisiology Department in Brazzaville from January 2013 to January 2014. Our sample consisted of 44 women (55%) and 36 men (45%), the sex ratio was 0.81. The average age was 37.5 ± 9.17 years, the average CD4 count was 153.13 ± 86,6 cell/mm3...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27739129/anti-pd1-induced-psoriasis-a-study-of-21-patients
#9
Julie Bonigen, Christine Raynaud-Donzel, José Hureaux, Nora Kramkimel, Astrid Blom, Géraldine Jeudy, Anne-Laure Breton, Thomas Hubiche, Christophe Bedane, Delphine Legoupil, Anne Pham-Ledard, Julie Charles, Maurice Pérol, Emilie Gérard, Patrick Combemale, Daphné Bonnet, Michèle-Léa Sigal, Emmanuel Mahé
Nivolumab (Opdivo(®) ), pembrolizumab (Keytruda(®) ), atezolizumab, and pidilizumabab are anti-PD1 monoclonal antibodies. Nivolumab is licensed in advanced melanoma and second-line therapy of advanced or metastatic non-small cell lung cancer. When activated, the programmed cell death (PD)-1 is implicated in the inhibition of the immune system. Anti-PD1 removes this inhibition and allows the immune system to control tumour cell progression.(1-4) Immune-mediated toxicity of this treatment have been reported, either organ-specific toxicities - i...
October 14, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27731512/retroperitoneal-laparoscopy-in-dogs-access-technique-working-space-and-surgical-anatomy
#10
Junemoe Jeong, Jonghyeok Ko, Hyunjoo Lim, Oh-Kyeong Kweon, Wan Hee Kim
OBJECTIVE: To develop and describe a laparoscopic retroperitoneal access technique, investigate working space establishment, and describe the surgical anatomy in the retroperitoneal space as an initial step for clinical application of retroperitoneal laparoscopy in dogs. STUDY DESIGN: Cadaveric and experimental study. ANIMALS: Cadaveric (n=8) and healthy (n=6) adult dogs. METHODS: The retroperitoneal access technique was developed in 3 cadavers based on the human technique and transperitoneal observation...
November 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27709274/-injuries-to-blood-vessels-near-the-heart-caused-by-central-venous-catheters
#11
J Abram, J Klocker, N Innerhofer-Pompernigg, M Mittermayr, M C Freund, N Gravenstein, V Wenzel
Injuries to blood vessels near the heart can quickly become life-threatening and include arterial injuries during central venous puncture, which can lead to hemorrhagic shock. We report 6 patients in whom injury to the subclavian artery and vein led to life-threatening complications. Central venous catheters are associated with a multitude of risks, such as venous thrombosis, air embolism, systemic or local infections, paresthesia, hemothorax, pneumothorax, and cervical hematoma, which are not always immediately discernible...
November 2016: Der Anaesthesist
https://www.readbyqxmd.com/read/27704508/childhood-tuberculosis-a-descriptive-study-in-a-pneumo-pediatrics-department-in-tunisia
#12
Houda Snène, Anissa Berraies, Besma Hamdi, Jamel Ammar, Hanadi Ouali, Agnes Hamzaoui
Objective to assess the different localizations of tuberculosis (TB) in children in a pneumopediatric department in Tunisia and to describe its diagnosis tools since clinical investigations of childhood TB are challenged by the paucibacillary nature of the disease and the difficulties in obtaining specimens. Methods Forty-six cases of TB in children were studied between 2008 and 2013. Clinical history, examination and chest radiography were reported. Several investigations have been conducted to confirm the diagnosis of TB such as: tuberculin skin test (TST), bacteriological and histological investigations...
April 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/27678833/pneumo-bag-morcellation-technique
#13
C E Ritter
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27661066/femtosecond-assisted-big-bubble-a-feasibility-study
#14
Vasilios F Diakonis, Sonia H Yoo, Victor Hernandez, Vardhaman P Kankariya, Florence Cabot, Maria P Fernandez-Jimenez, Sander R Dubovy, Jean-Marie Parel
PURPOSE: To evaluate the feasibility of femtosecond laser-assisted (FA) tunnel creation as a pretreatment for creating a big bubble (BB) to pneumo-dissect the corneal stroma from Descemet membrane. METHODS: Five human cadaver eyes received pretreatment using a femtosecond laser. An intrastromal tunnel, along with a side cut, was achieved using customized femtosecond corneal disruption (custom mask). Before treatment, optical coherence tomography was performed and the intrastromal tunnel was intended to achieve a parallel orientation with respect to the corneal endothelial cell layer (50 µm above the endothelium)...
September 21, 2016: Cornea
https://www.readbyqxmd.com/read/27583090/-tuberculous-pyopneumothorax-about-18-cases
#15
Souhi Hicham, El Ouazzani Hanane, Janah Hicham, Rhorfi Ismaïl, Abid Ahmed
Tuberculous pyopneumothorax is a rare but serious complication of evolutive pulmonary tuberculosis. We report a series of 18 cases with tuberculous pyopneumothorax admitted to the Pneumo-Phthisiology Department of the Mohammed V Military Teaching Hospital in Rabat between January 2005 and December 2009. Our study included 15 men and 3 women, the average age was 35 ± 7 years. 4 patients were diabetic. Smoking was found in 9 cases. Right-sided pneumothorax was found in 13 cases. Chest radiograph showed cavitary lesions in 15 patients and extensive bilateral lesions in 8 cases...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27364880/three-episodes-of-kawasaki-disease-including-one-after-the-pneumo-23-vaccine-in-a-child-with-a-family-history-of-kawasaki-disease
#16
Barbara Kraszewska-Głomba, Ernest Kuchar, Leszek Szenborn
No abstract text is available yet for this article.
October 2016: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/27344665/piribedil-for-the-treatment-of-motor-and-non-motor-symptoms-of-parkinson-disease
#17
REVIEW
Santiago Perez-Lloret, Olivier Rascol
Dopamine agonists are well-established symptomatic medications for treating early and advanced Parkinson disease (PD). Piribedil was one of the first agonists to be marketed (1969) and is widely used as an extended-release oral formulation in European, Latin-American, and Asian countries. Piribedil acts as a non-ergot partial dopamine D2/D3-selective agonist, blocks alpha2-adrenoreceptors and has minimal effects on serotoninergic, cholinergic, and histaminergic receptors. Animal models support the efficacy of piribedil to improve parkinsonian motor symptoms with a lower propensity than levodopa to induce dyskinesia...
August 2016: CNS Drugs
https://www.readbyqxmd.com/read/27161643/study-of-two-separate-types-of-macrolide-resistant-mycoplasma-pneumoniae-outbreaks
#18
Yingshuo Wang, Qian Ye, Dehua Yang, Zhimin Ni, Zhimin Chen
To study the complete natural process of a Mycoplasma pneumoniae outbreak in a semiclosed room such as a primary school room, we investigated two separate M. pneumoniae outbreaks involving 81 students in total in two primary schools in Hangzhou, China. M. pneumoniae isolates from pharyngeal swabs were detected by fluorescence quantitative real-time PCR (RT-PCR) and culture. The class in school M had 39 students, with 12 (30.8%) with positive M. pneumoniae detection results. The class from school J had 42 students, with 13 (31...
July 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27107703/herbo-mineral-based-schiff-base-ligand-and-its-metal-complexes-synthesis-characterization-catalytic-potential-and-biological-applications
#19
Abdul Kareem, Laxmi, Mohammad Arshad, Shahab A A Nami, Nahid Nishat
Schiff base ligand, (L), derived from condensation reaction of 1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, (curcumin), with pyridine-3-carboxamide, (nicotinamide), and its complexes of Co(II), Ni(II) and Cu(II) ions, containing 1,10-phenanthroline as auxiliary ligand were synthesized and characterized by various physico-chemical techniques. From the micro analytical data, the stoichiometry of the complexes 1:1 (metal: ligand) was ascertained. The Co(II) and Cu(II) forms octahedral complexes, while the geometric structure around Ni(II) atom can be described as square planar...
July 2016: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/27096478/-legionella-pneumonia-after-the-use-of-cpap-equipment
#20
Jaap M Stolk, Anne Russcher, Erika P M van Elzakker, Emile F Schippers
Continuous positive airway pressure (CPAP) equipment can be colonised by Legionellae and might cause Legionella pneumonia in the user. However, there is no reported case of Legionella pneumonia related to CPAP equipment in which an identical Legionella was found in both the patient and the CPAP equipment. A 51-year-old man came to the Emergency Department with fever, confusion and dyspnoea that had been present for 3 days. His medical history included obstructive sleep apnoea, for which he had been using CPAP therapy at home for 10 weeks...
2016: Nederlands Tijdschrift Voor Geneeskunde
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