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https://www.readbyqxmd.com/read/28081317/hormone-therapy-in-hypospadias-surgery-a-survey-on-the-current-practice-in-turkey
#1
Gülnur Göllü Bahadır, Ergun Ergün, Onur Telli, Farid Khanmammadov, Ahmet Murat Çakmak
BACKGROUND/AIM: Nowadays surgical intervention is possible in smaller phalluses and younger children with hypospadias disease. Different hormone treatments with different doses, modalities, indications, and treatment times come along with some disputes. The aim of this study is to evaluate the management approaches in hypospadias surgery of surgeons in regards to hormone preparations. MATERIALS AND METHODS: Questionnaires were sent via e-mail to 110 actively working pediatric surgeons and urologists...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28077148/linking-communities-to-formal-health-care-providers-through-village-health-teams-in-rural-uganda-lessons-from-linking-social-capital
#2
Laban Kashaija Musinguzi, Emmanueil Benon Turinawe, Jude T Rwemisisi, Daniel H de Vries, David K Mafigiri, Denis Muhangi, Marije de Groot, Achilles Katamba, Robert Pool
BACKGROUND: Community-based programmes, particularly community health workers (CHWs), have been portrayed as a cost-effective alternative to the shortage of health workers in low-income countries. Usually, literature emphasises how easily CHWs link and connect communities to formal health care services. There is little evidence in Uganda to support or dispute such claims. Drawing from linking social capital framework, this paper examines the claim that village health teams (VHTs), as an example of CHWs, link and connect communities with formal health care services...
January 11, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28076535/-femicides-in-ethnic-and-racialized-groups-syntheses
#3
Stela Nazareth Meneghel, Betty Ruth Lozano Lerma
The text entitled "Femicides in ethnic and racialized groups: syntheses" presents some of the discussions that took place during a seminar on this topic in Buenaventura. Buenaventura is the main Colombian port on the Pacific, a region rich in minerals and a corridor for the movement of goods, which makes it a strategic territory and a center for disputes. At the seminar, the social and political determinants of femicide were discussed, understanding it as a tactic of waging war against women. The forum provided a space for academic discussion, but also for grievances over inter-personal violence, the manifestation of feelings and the elaboration of pain and grief through the medium of art...
January 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28073392/does-the-dilution-effect-generally-occur-in-animal-diseases
#4
Zheng Y X Huang, Yang Yu, Frank VAN Langevelde, Willem F DE Boer
The dilution effect (DE) has been reported in many diseases, but its generality is still highly disputed. Most current criticisms of DE are related to animal diseases. Particularly, some critical studies argued that DE is less likely to occur in complex environments. Here our meta-analyses demonstrated that the magnitude of DE did not differ between animal vs plant diseases. Moreover, DE generally occurs in all three subgroups of animal diseases, namely direct-transmitted diseases, vector-borne diseases and diseases caused by parasites with free-living stages...
January 11, 2017: Parasitology
https://www.readbyqxmd.com/read/28062594/survey-of-800-datasets-from-human-tissue-and-body-fluid-reveals-xenomirs-are-likely-artifacts
#5
Wenjing Kang, Claus Heiner Bang-Bertelsen, Anja Holm, Anna Houben, Anne Holt Müller, Thomas Thymann, Flemming Pociot, Xavier Estivill, Marc Riemer Friedländer
miRNAs are small 22 nucleotide RNAs that can post-transcriptionally regulate gene expression. It has been proposed that dietary plant miRNAs can enter the human bloodstream and regulate host transcripts, however these findings have been widely disputed. We here conduct the first comprehensive meta-study in the field, surveying the presence and abundances of cross-species miRNAs (xenomiRs) in 824 sequencing datasets from various human tissues and body fluids. We find that xenomiRs are commonly present in tissues (17%) and body fluids (69%), however the abundances are low, comprising 0...
January 6, 2017: RNA
https://www.readbyqxmd.com/read/28058053/survival-regression-modeling-strategies-in-cvd-prediction
#6
Mahnaz Barkhordari, Mojgan Padyab, Mahsa Sardarinia, Farzad Hadaegh, Fereidoun Azizi, Mohammadreza Bozorgmanesh
BACKGROUND: A fundamental part of prevention is prediction. Potential predictors are the sine qua non of prediction models. However, whether incorporating novel predictors to prediction models could be directly translated to added predictive value remains an area of dispute. The difference between the predictive power of a predictive model with (enhanced model) and without (baseline model) a certain predictor is generally regarded as an indicator of the predictive value added by that predictor...
April 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28049867/elephant-s-breast-milk-contains-large-amounts-of-glucosamine
#7
Zenta Takatsu, Muneya Tsuda, Akio Yamada, Hiroshi Matsumoto, Akira Takai, Yasuhiro Takeda, Mitsunori Takase
Hand-reared elephant calves that are nursed with milk substitutes sometimes suffer bone fractures, probably due to problems associated with nutrition, exercise, sunshine levels and/or genetic factors. As we were expecting the birth of an Asian elephant (Elephas maximus), we analyzed elephant's breast milk to improve the milk substitutes for elephant calves. Although there were few nutritional differences between conventional substitutes and elephant's breast milk, we found a large unknown peak in the breast milk during high-performance liquid chromatography-based amino acid analysis and determined that it was glucosamine (GlcN) using liquid chromatography/mass spectrometry...
December 31, 2016: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28043668/contrasting-association-between-alcohol-consumption-and-risk-of-myocardial-infarction-and-heart-failure-two-prospective-cohorts
#8
Susanna C Larsson, Alice Wallin, Alicja Wolk
BACKGROUND: The potential cardioprotective effect of light-to-moderate alcohol consumption is disputed, and the association between heavy drinking and heart failure (HF) risk is unclear. We examined the association between alcohol consumption and risk of myocardial infarction (MI) and HF in two prospective cohorts. METHODS: We analyzed data from the Cohort of Swedish Men (40,590 men) and the Swedish Mammography Cohort (34,022 women). Participants were free of ischemic heart disease and HF at baseline...
December 28, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28034764/the-concept-of-the-personal-vitamin-d-response-index
#9
REVIEW
Carsten Carlberg, Afrozul Haq
Humans are able to synthesize vitamin D3 in their skin when exposed to UV-B, but seasonal variations, textile coverage and predominant indoor activities often make supplementation with the compound necessary. There is some dispute on the desired vitamin D status, measured via the serum concentration of the most stable vitamin D3 metabolite, 25-hydroxyvitamin D3, and the respective recommended daily supplementation. A possible answer may be provided by the concept of the personal vitamin D response index describing the efficiency of the molecular response to supplementation with vitamin D...
December 26, 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28031594/suicide-in-rural-central-india-profile-of-attempters-of-deliberate-self-harm-presenting-to-padhar-hospital-in-madhya-pradesh
#10
Johann Alex Ebenezer, Vivek Joge
BACKGROUND: Suicide is a significant public health issue. India currently has the largest number of suicides in the world and has a disproportionate number of youth suicides including young women. The studies on patterns of suicide in rural central India are sparse, particularly among tribal communities. AIMS: The aim of this study is to describe the profile of suicide attempters presenting to a secondary-level hospital in rural central India and identify areas for potential future research toward preventive strategies...
November 2016: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28030597/enoblock-does-not-inhibit-the-activity-of-the-glycolytic-enzyme-enolase
#11
Nikunj Satani, Yu-Hsi Lin, Naima Hammoudi, Sudhir Raghavan, Dimitra K Georgiou, Florian L Muller
Inhibition of glycolysis is of great potential for the treatment of cancer. However, inhibitors of glycolytic enzymes with favorable pharmacological profiles have not been forthcoming. Due to the nature of their active sites, most high-affinity transition-state analogue inhibitors of glycolysis enzymes are highly polar with poor cell permeability. A recent publication reported a novel, non-active site inhibitor of the glycolytic enzyme Enolase, termed ENOblock (N-[2-[2-2-aminoethoxy)ethoxy]ethyl]4-4-cyclohexylmethyl)amino]6-4-fluorophenyl)methyl]amino]1,3,5-triazin-2-yl]amino]benzeneacetamide)...
2016: PloS One
https://www.readbyqxmd.com/read/28030533/physical-and-physiological-profile-of-wrestler-athletes-short-review
#12
Helmi Chaabene, Yassine Negra, Raja Bouguezzi, Bessem Mkaouer, Emerson Franchini, Ursula Julio, Younés Hachana
Wrestling is one of the oldest combat sports, disputed since the ancient Greek Olympic Games. This combat sport discipline has caught the attention of scientists since 1943 which is the date that matches the appearance of the first scientific research dealing with wrestling. The current short review aimed to summarize and critically analyze the scientific literature related to wrestling's physical and physiological attributes and to provide practical recommendations for testing/training together with new perspective and areas of future scientific research...
December 24, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28012892/head-anatomy-of-adult-coniopteryx-pygmaea-enderlein-1906-effects-of-miniaturization-and-the-systematic-position-of-coniopterygidae-insecta-neuroptera
#13
Susanne Randolf, Dominique Zimmermann, Ulrike Aspöck
External and internal head structures of adult Coniopteryx pygmaea Enderlein, 1906, one of the smallest known lacewings, are described in detail for the first time. Possible effects of miniaturization and two hypotheses on the phylogenetic position of Coniopterygidae are evaluated and compared with data from literature. Several convergent modifications in C. pygmaea and other miniaturized insect species are outlined, e.g., a relative increase in the size of the brain, simplification of the tracheal system with respect to the number of tracheae, and reduction of the number of ommatidia and diameter of the facets...
December 21, 2016: Arthropod Structure & Development
https://www.readbyqxmd.com/read/28009005/low-abundance-of-archaeorhizomycetes-among-fungi-in-soil-metatranscriptomes
#14
Michal Choma, Jiří Bárta, Hana Šantrůčková, Tim Urich
The Archaeorhizomycetes are recently discovered fungi with poorly resolved ecology. Even their abundance in soil fungal communities is currently disputed. Here we applied a PCR-independent, RNA-based metatranscriptomic approach to determine their abundance among fungi in eleven different soils across Europe. Using small subunit (SSU) ribosomal RNA transcripts as marker, we detected Archaeorhizomycetes in 17 out of 28 soil metatranscriptomes. They had average relative SSU rRNA abundance of 2.0% with a maximum of 9...
December 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28006856/the-thoracic-outlet-syndromes-part-2-the-arterial-venous-neurovascular-and-disputed-thoracic-outlet-syndromes
#15
Mark A Ferrante, Nicole D Ferrante
The thoracic outlet syndromes (TOSs) are a group of etiologically and clinically distinct disorders with 1 feature in common: compression of 1 or more neurovascular elements as they traverse the thoracic outlet. The medical literature reflects 5 TOSs: arterial, venous, traumatic neurovascular, true neurogenic, and disputed. Of these, the first 4 demonstrate all of the features expected of a syndrome, whereas disputed TOS does not, causing many experts doubt its existence altogether. Thus, some categorize disputed TOS as cervicoscapular pain syndrome rather than as a type of TOS...
December 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/28006844/the-thoracic-outlet-syndromes-part-1-overview-of-the-thoracic-outlet-syndromes-and-review-of-true-neurogenic-thoracic-outlet-syndrome
#16
Mark A Ferrante, Nicole D Ferrante
The thoracic outlet syndromes (TOSs) are a group of etiologically and clinically distinct disorders with 1 feature in common: compression of 1 or more neurovascular elements as they traverse the thoracic outlet. The medical literature reflects 5 TOSs: arterial, venous, traumatic neurovascular, true neurogenic, and disputed. Of these, the first 4 demonstrate all of the features expected of a syndrome, whereas disputed TOS does not, causing many experts to doubt its existence altogether. Thus, some categorize disputed TOS as a cervicoscapular pain syndrome rather than as a type of TOS...
December 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/28005547/the-legal-strength-of-international-health-instruments-what-it-brings-to-global-health-governance
#17
Haik Nikogosian, Ilona Kickbusch
Public health instruments have been under constant development and renewal for decades. International legal instruments, with their binding character and strength, have a special place in this development. The start of the 21st century saw, in particular, the birth of the first World Health Organization (WHO)-era health treaties - the WHO Framework Convention on Tobacco Control (WHO FCTC) and its first Protocol. The authors analyze the potential impact of these instruments on global health governance and public health, beyond the traditional view of their impact on tobacco control...
September 4, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28001135/a-survey-of-physicians-attitudes-toward-decision-making-authority-for-initiating-and-withdrawing-va-ecmo-results-and-ethical-implications-for-shared-decision-making
#18
Ellen C Meltzer, Natalia S Ivascu, Meredith Stark, Alexander V Orfanos, Cathleen A Acres, Paul J Christos, Thomas Mangione, Joseph J Fins
OBJECTIVE: Although patients exercise greater autonomy than in the past, and shared decision making is promoted as the preferred model for doctor-patient engagement, tensions still exist in clinical practice about the primary locus of decision-making authority for complex, scarce, and resource-intensive medical therapies: patients and their surrogates, or physicians. We assessed physicians' attitudes toward decisional authority for adult venoarterial extracorporeal membrane oxygenation (VA-ECMO), hypothesizing they would favor a medical locus...
2016: Journal of Clinical Ethics
https://www.readbyqxmd.com/read/27996996/-ecg-for-non-competitive-sports-in-childhood-strengths-and-disputes
#19
Elena Poggi, Alessandro Giannattasio, Sara Bolloli, Andrea Beccaria, Paola Mezzano, Paola Rocca, Cecilia Del Vecchio
BACKGROUND: Sport is very important for health promotion and conservation. Active lifestyle and regular exercise reduce cardiovascular disease incidence. The Italian Ministry of Health issued the Law Decree no. 243 (10/18/2014) concerning "guidelines for certification about non-competitive sports" to promote safety in sports. This regulation defines the activities for which a certificate is required, the professional actors involved and the clinical exams to be performed according to the patient's health status...
November 2016: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/27996923/a-framework-for-unrestricted-prenatal-whole-genome-sequencing-respecting-and-enhancing-the-autonomy-of-prospective-parents
#20
Stephanie C Chen, David T Wasserman
Noninvasive, prenatal whole genome sequencing (NIPW) may be a technological reality in the near future, making available a vast array of genetic information early in pregnancy at no risk to the fetus or mother. Many worry that the timing, safety, and ease of the test will lead to informational overload and reproductive consumerism. The prevailing response among commentators has been to restrict conditions eligible for testing based on medical severity, which imposes disputed value judgments and devalues those living with eligible conditions...
January 2017: American Journal of Bioethics: AJOB
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