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https://www.readbyqxmd.com/read/28916433/resilience-in-families-of-children-with-autism-and-sleep-problems-using-mixed-methods
#1
Cristine A Roberts, Jennifer Hunter, An-Lin Cheng
PURPOSE: About 80% of children with autism spectrum disorder (ASD) have sleep problems that may disrupt optimal family functioning. We explored the impact of sleep problems on families' resilience. DESIGN AND METHODS: An explanatory sequential mixed methods design was used to discern whether resilience differed between families whose children with ASD have or do not have sleep problems, to seek predictors for family hardiness/resilience, and to determine whether narrative findings support, expand, or conflict quantitative findings...
September 12, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28915473/endocrine-disrupting-compounds-in-streams-in-israel-and-the-palestinian-west-bank-implications-for-transboundary-basin-management
#2
Pniela Dotan, Maayan Yeshayahu, Wa'd Odeh, Nina Gordon-Kirsch, Ludmila Groisman, Nader Al-Khateeb, Alfred Abed Rabbo, Alon Tal, Shai Arnon
Endocrine disrupting compounds (EDCs) frequently enter surface waters via discharges from wastewater treatment plants (WWTPs), as well as from industrial and agricultural activities, creating environmental and health concerns. In this study, selected EDCs were measured in water and sediments along two transboundary streams flowing from the Palestinian Authority (PA) into Israel (the Zomar-Alexander and Hebron-Beer Sheva Streams). We assessed how the complicated conflict situation between Israel and the PA and the absence of a coordinated strategy and joint stream management commission influence effective EDC control...
September 12, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28914546/defibrotide-an-oligonucleotide-for-sinusoidal-obstruction-syndrome
#3
May T Aziz, Payal P Kakadiya, Samantha M Kush, Kylie Weigel, Denise K Lowe
OBJECTIVE: To review the efficacy and safety of defibrotide as well as its pharmacology, mechanism of action, pharmacokinetics (PK), drug-drug interactions, dosing, cost considerations, and place in therapy. DATA SOURCES: A PubMed search was performed through August 2017 using the terms defibrotide, oligonucleotide, hepatic veno-occlusive disease (VOD), sinusoidal obstruction syndrome (SOS), and hematopoietic cell transplantation (HCT). Other data sources were from references of identified studies, review articles, and conference abstracts plus manufacturer product labeling and website, the Food and Drug Administration website, and clinicaltrials...
September 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28913595/health-professionals-make-their-choice-pharmaceutical-industry-leaders-understandings-of-conflict-of-interest
#4
Quinn Grundy, Lisa Tierney, Christopher Mayes, Wendy Lipworth
Conflicts of interest, stemming from relationships between health professionals and the pharmaceutical industry, remain a highly divisive and inflammatory issue in healthcare. Given that most jurisdictions rely on industry to self-regulate with respect to its interactions with health professionals, it is surprising that little research has explored industry leaders' understandings of conflicts of interest. Drawing from in-depth interviews with ten pharmaceutical industry leaders based in Australia, we explore the normalized and structural management of conflicts of interest within pharmaceutical companies...
September 14, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28912667/how-do-nurse-consultant-job-characteristics-impact-on-job-satisfaction-an-australian-quantitative-study
#5
Michelle Giles, Vicki Parker, Rebecca Mitchell, Jane Conway
BACKGROUND: There is a direct link between job satisfaction, nurses' job performance and improved patient outcomes. Understanding what job characteristics influence job satisfaction is vital if health organizations are to optimize individual employee satisfaction and performance. This is particularly necessary in the Nurse Consultant role, which is a multifaceted role that has evolved to meet the dynamic and changing needs of health services. This study aims to examine how job characteristics influence Nurse Consultant job satisfaction and identify differences across metropolitan and rural contexts...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28911214/growth-regulation-by-estrogen-in-breast-cancer-1-greb1-is-a-novel-progesterone-responsive-gene-required-for-human-endometrial-stromal-decidualization
#6
Alison J Camden, Maria M Szwarc, Sangappa B Chadchan, Francesco J DeMayo, Bert W O'Malley, John P Lydon, Ramakrishna Kommagani
STUDY QUESTION: Is Growth Regulation by Estrogen in Breast Cancer 1 (GREB1) required for progesterone-driven endometrial stromal cell decidualization? SUMMARY ANSWER: GREB1 is a novel progesterone-responsive gene required for progesterone-driven human endometrial stromal cell (HESC) decidualization. WHAT IS KNOWN ALREADY: Successful establishment of pregnancy requires HESCs to transform from fibroblastic to epithelioid cells in a process called decidualization...
September 1, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28906284/effect-of-transfusion-on-mortality-and-other-adverse-events-among-critically-ill-septic-patients-an-observational-study-using-a-marginal-structural-cox-model
#7
Claire Dupuis, Maité Garrouste-Orgeas, Sébastien Bailly, Christophe Adrie, Dany Goldgran-Toledano, Elie Azoulay, Stéphane Ruckly, Guillaume Marcotte, Bertrand Souweine, Michael Darmon, Yves Cohen, Carole Schwebel, Guillaume Lacave, Lila Bouadma, Jean-Francois Timsit
OBJECTIVES: RBC transfusion is often required in patients with sepsis. However, adverse events have been associated with RBC transfusion, raising safety concerns. A randomized controlled trial validated the 7 g/dL threshold, but previously transfused patients were excluded. Cohort studies led to conflicting results and did not handle time-dependent covariates and history of treatment. Additional data are thus warranted to guide patient's management. DESIGN: To estimate the effect of one or more RBC within 1 day on three major outcomes (mortality, ICU-acquired infections, and severe hypoxemia) at day 30, we used marginal structural models...
September 12, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28904217/two-orthoptic-treatments-in-dragged-fovea-diplopia-syndrome
#8
Silvia Maddii, Ilaria Biagini, Alessia Aragno, Mario Scrivanti, Barbara Giambene, Stanislao Rizzo, Gianni Virgili
BACKGROUND: "Dragged-fovea diplopia syndrome" is a type of central binocular diplopia that is secondary to a foveal displacement, caused by epiretinal membranes (ERMs) or other macular diseases. Its management is difficult, because prisms are not effective. CASE REPORTS: Two cases of dragged-fovea diplopia syndrome were presented. Both patients were affected with a unilateral epiretinal membrane. Therefore, the pathophysiology underlying their diplopia was the conflict between central and peripheral fusion mechanisms...
January 2017: American Orthoptic Journal
https://www.readbyqxmd.com/read/28902700/effectiveness-of-collaboration-between-emergency-department-and-intensive-care-unit-teams-on-mortality-rates-of-patients-presenting-with-critical-illness-a-systematic-review
#9
Kerchelle McDowald, Svetlana Direktor, Elizabeth A Hynes, Anna Sahadeo, Margaret E Rogers
BACKGROUND: The increasing volume of adult patients with critical illness entering emergency departments (EDs) burdens the resources of EDs worldwide. This subpopulation faces a high risk of mortality because they require specialized care which many EDs are not yet poised to deliver. An element crucial to delivering care and decreasing the mortality of critically ill patients in the ED is expert collaborative practice across disciplines. Several ED and intensive care unit (ICU) collaborative models exist including: emergency department intensive care units (EDICU) and medical emergency teams (MET)...
September 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28901787/medication-management-strategies-used-by-older-adults-with-heart-failure-a-systems-based-analysis
#10
Robin S Mickelson, Richard J Holden
BACKGROUND: Older adults with heart failure use strategies to cope with the constraining barriers impeding medication management. Strategies are behavioral adaptations that allow goal achievement despite these constraining conditions. When strategies do not exist, are ineffective or maladaptive, medication performance and health outcomes are at risk. While constraints to medication adherence are described in literature, strategies used by patients to manage medications are less well-described or understood...
September 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28901625/systemic-challenges-in-bipolar-disorder-management-a-patient-centered-approach
#11
Anastasiya Nestsiarovich, Nathaniel G Hurwitz, Stuart J Nelson, Annette S Crisanti, Berit Kerner, Matt J Kuntz, Alicia N Smith, Emma Volesky, Quentin L Schroeter, Jason L DeShaw, S Stanley Young, Robert L Obenchain, Ronald L Krall, Kimmie Jordan, Jan Fawcett, Mauricio Tohen, Douglas J Perkins, Christophe G Lambert
OBJECTIVES: As part of a series of Patient-Centered Outcomes Research Institute-funded large-scale retrospective observational studies on bipolar disorder (BD) treatments and outcomes, we sought the input of patients with BD and their family members to develop research questions. We aimed to identify systemic root causes of patient-reported challenges with BD management in order to guide subsequent studies and initiatives. METHODS: Three focus groups were conducted where patients and their family members (total n = 34) formulated questions around the central theme, "What do you wish you had known in advance or over the course of treatment for BD?" In an affinity mapping exercise, participants clustered their questions and ranked the resulting categories by importance...
September 13, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28895700/conflict-of-interest-nuances-between-principles-and-the-aim
#12
María E Serra
A conflict of interest exists when a health care provider's primary interest is at risk of being biased by a secondary interest that would cause harm. This concerns the different fields of professional practice. Based on a supplement of the Journal of the American Medical Association (JAMA) about conflicts of interest inviting to analyze the situation under the "Do No Harm" ethical principle, diverse scenarios are described, showing the intricacy and controversy of this topic. Elimination of conflict is not always possible, and there is consensus that science-based interactions among private organizations, health care providers and health institutions can be beneficial to patients...
October 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28890925/on-the-road-to-becoming-a-responsible-leader-a-simulation-based-training-approach-for-final-year-medical-students
#13
Marion Schmidt-Huber, Janine Netzel, Jan Kiesewetter
Background and objective: There is a need for young physicians to take a responsible role in clinical teams, comparable to a leadership role. However, today's medical curricula barely consider the development of leadership competencies. Acquisition of leadership skills are currently a by-product of medical education, even though it seems to be a competency relevant for physicians' success. Therefore, an innovative leadership training program for young physicians was developed and validated. Training conceptualisation were based upon findings of critical incidents interviews (N=19) with relevant personnel (e...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/28888498/parental-expectations-of-support-from-healthcare-providers-during-pediatric-life-threatening-illness-a-secondary-qualitative-analysis
#14
Kim Mooney-Doyle, Maiara Rodrigues Dos Santos, Regina Szylit, Janet A Deatrick
PURPOSES: To explain parental expectations of support from healthcare providers for their parenting roles and goals during a child's life-threatening illness (LTI). DESIGN AND METHODS: Qualitative interpretive study guided by the Family Adjustment and Adaptation Response Model. Thematic analyses were conducted with data from 31 semi-structured interviews of parents of children with LTI using systematic strategies to ensure rigor including audit trails and prolonged engagement...
September 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28886087/hong-kong-hospital-authority-resource-efficiency-evaluation-via-a-novel-dea-malmquist-model-and-tobit-regression-model
#15
Hainan Guo, Yang Zhao, Tie Niu, Kwok-Leung Tsui
The Hospital Authority (HA) is a statutory body managing all the public hospitals and institutes in Hong Kong (HK). In recent decades, Hong Kong Hospital Authority (HKHA) has been making efforts to improve the healthcare services, but there still exist some problems like unfair resource allocation and poor management, as reported by the Hong Kong medical legislative committee. One critical consequence of these problems is low healthcare efficiency of hospitals, leading to low satisfaction among patients. Moreover, HKHA also suffers from the conflict between limited resource and growing demand...
2017: PloS One
https://www.readbyqxmd.com/read/28884902/the-role-of-elimination-diets-in-atopic-dermatitis-a-comprehensive-review
#16
REVIEW
Neil R Lim, Mary E Lohman, Peter A Lio
BACKGROUND/OBJECTIVES: Diet is a common concern for individuals with atopic dermatitis (AD) and their families. Studies regarding the effect of dietary interventions on AD exist, but many are limited by small size and poor design. Conflicting results present a challenge to clinicians seeking to counsel patients. The aim of the current review is to examine the published literature and generate helpful conclusions for clinicians faced with dietary questions in AD. METHODS: A PubMed search was performed focusing on dietary interventions for AD in children and adults through July 2016...
September 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28884005/gynecological-cancers-an-alternative-approach-to-healing
#17
REVIEW
Srdjan Saso, Benjamin P Jones, Timothy Bracewell-Milnes, Gulsen Huseyin, Deborah C Boyle, Giuseppe Del Priore, James Richard Smith
Grief and hope are two conflicting emotions that a patient recently diagnosed with cancer has to master. The real challenge for gynecologic oncologists is how to reach out. Conventional wisdom states that offering patients focus and belief when combating cancer in their lives allows them to embrace hope with greater confidence, which minimizes their grief. Three pictorial models are presented: '4-cusp approach' model used at the initial consultation; 'tapestry of bereavement or landscape of grief' model at the postsurgery consultation; and 'Venn-diagram' model at any time during patient management...
August 2017: Future Science OA
https://www.readbyqxmd.com/read/28882150/care-managers-professional-choices-ethical-dilemmas-and-conflicting-expectations
#18
Siri Tønnessen, Gøril Ursin, Berit Støre Brinchmann
BACKGROUND: Care-managers are responsible for the public administration of individual healthcare decisions and decide on the volume and content of community healthcare services given to a population. The purpose of this study was to investigate the conflicting expectations and ethical dilemmas these professionals encounter in their daily work with patients and to discuss the clinical implications of this. METHODS: The study had a qualitative design. The data consisted of verbatim transcripts from 12 ethical reflection group meetings held in 2012 at a purchaser unit in a Norwegian city...
September 7, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28881932/health-facility-management-and-access-a-qualitative-analysis-of-challenges-to-seeking-healthcare-for-children-under-five-in-uganda
#19
Elizabeth Palchik Allen, Wilson Winstons Muhwezi, Dorcus Kiwanuka Henriksson, Anthony Kabanza Mbonye
While several studies have documented the various barriers that caretakers of children under five routinely confront when seeking healthcare in Uganda, few have sought to capture the ways in which caretakers themselves prioritize their own barriers to seeking services. To that end, we asked focus groups of caretakers to list their five greatest challenges to seeking care on behalf of children under five. Using qualitative content analysis, we grouped responses according to four categories: (1) geographical access barriers; (2) facility supplies, staffing, and infrastructural barriers; (3) facility management and administration barriers (e...
September 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28880756/how-greek-nurses-perceive-and-overcome-the-barriers-in-implementing-treatment-for-pressure-ulcers-against-the-odds
#20
E Kaba, M Kelesi, A Stavropoulou, D Moustakas, G Fasoi
OBJECTIVE: Although the occurrence of pressure ulcers (PUs) is now considered as an indicator of poor quality nursing care, questions and concerns remain regarding situations where PUs were unavoidable, irrespective of the care provided. The aim of this study was to explore Greek nurses' perceptions about the barriers involved and to identify the factors that influence care planning in PU treatment. METHOD: A grounded theory approach was used and semi-structured interviews were conducted with nurses who provided pressure care to clients in a rehabilitation centre in Greece...
September 1, 2017: Journal of Wound Care
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