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https://www.readbyqxmd.com/read/28549603/an-augmented-iterative-method-for-identifying-a-stress-free-reference-configuration-in-image-based-biomechanical-modeling
#1
Manuel K Rausch, Martin Genet, Jay D Humphrey
Continued advances in computational power and methods have enabled image-based biomechanical modeling to become an important tool in basic science, diagnostic and therapeutic medicine, and medical device design. One of the many challenges of this approach, however, is identification of a stress-free reference configuration based on in vivo images of loaded and often prestrained or residually stressed soft tissues and organs. Fortunately, iterative methods have been proposed to solve this inverse problem, among them Sellier's method...
May 5, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28549313/the-persistent-shadow-of-suicide-ideation-and-attempts-in-a-high-risk-group-of-psychiatric-patients-a-focus-for-intervention
#2
Jane G Tillman, A Jill Clemence, Robyn Cree, Katie C Lewis, Jennifer L Stevens, David Reiss
OBJECTIVE: Patients with a history of suicidal ideation or attempts, especially if they have serious psychopathology with repeated hospitalizations, are burdened by ongoing risk for suicide. We studied this high-risk group to assess their psychological status following their most recent suicide attempt, in contrast to equally ill patients without a suicide history. Further, among suicidal patients, we compared those with only ideation, with a non-medically serious suicide attempt and with medically serious suicide attempts...
May 18, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28549263/prevalence-reasons-perceived-effects-and-correlates-of-medical-marijuana-use-a-review
#3
REVIEW
Ji-Yeun Park, Li-Tzy Wu
BACKGROUND: The use of marijuana for medical purposes is now legal in some U.S. states and other jurisdictions, such as Canada, and Israel. Despite the widespread legalization of medical marijuana globally, there is limited information on patterns and correlates of medical marijuana use (MMU). We conducted a literature review to assess prevalence, reasons, perceived effects, and correlates of MMU among adolescents and adults. METHODS: We searched peer-reviewed articles in English between January 1996 and August 2016 from several databases (PubMed, Google Scholar, Embase, CINAHL, and PsycINFO) using different combinations of keywords...
May 16, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28548865/a-national-survey-of-canadian-psychiatrists-attitudes-toward-medical-assistance-in-death
#4
Skye Rousseau, Sarah Turner, Harvey Max Chochinov, Murray W Enns, Jitender Sareen
BACKGROUND: Bill C-14 allows for medical assistance in dying (MAID) for patients who have intolerable physical or psychological suffering that occurs in the context of a reasonably foreseeable death. In Canada, psychiatrist support for MAID on the basis of mental illness and beliefs influencing level of support are unknown. The objectives of this research were to 1) determine if psychiatrists are supportive of MAID under certain conditions and on the basis of mental illness and 2) determine what factors are related to psychiatrist support for MAID on the basis of mental illness...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28548368/developing-minimum-clinical-standards-for-physiotherapy-in-south-african-icus-a-qualitative-study
#5
Heleen van Aswegen, Shane Patman, Natascha Plani, Susan Hanekom
RATIONALE, AIMS, AND OBJECTIVES: Physiotherapists are integral members of the intensive care unit (ICU) team. Clinicians working in ICU are dependent on their own experience when making decisions regarding individual patient management thus resulting in variation in clinical practice. No formalized clinical practice guidelines or standards exist for the educational profile or scope of practice requirements for ICU physiotherapy. This study explored perceptions of physiotherapists on minimum clinical standards that ICU physiotherapists should adhere to for delivering safe, effective physiotherapy services to critically ill patients...
May 26, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28546381/adjunct-therapies-for-refractory-status-asthmaticus-in-children
#6
Kyle J Rehder
Asthma exacerbation is a common reason for children to present to the emergency department. If primary therapies fail to halt the progression of an asthma flare, status asthmaticus often leads to hospital, and potentially ICU, admission. Following the initial administration of inhaled β agonists and systemic corticosteroids, a wide array of adjunct medical therapies may be used to treat status asthmaticus. Unfortunately, the data supporting the use of these adjunct therapies are often unclear, conflicting, or absent...
June 2017: Respiratory Care
https://www.readbyqxmd.com/read/28546090/safety-and-tolerability-of-long-acting-cabotegravir-injections-in-hiv-uninfected-men-eclair-a-multicentre-double-blind-randomised-placebo-controlled-phase-2a-trial
#7
Martin Markowitz, Ian Frank, Robert M Grant, Kenneth H Mayer, Richard Elion, Deborah Goldstein, Chester Fisher, Magdalena E Sobieszczyk, Joel E Gallant, Hong Van Tieu, Winkler Weinberg, David A Margolis, Krischan J Hudson, Britt S Stancil, Susan L Ford, Parul Patel, Elizabeth Gould, Alex R Rinehart, Kimberly Y Smith, William R Spreen
BACKGROUND: Cabotegravir (GSK1265744) is an HIV-1 integrase strand transfer inhibitor with potent antiviral activity and a long half-life when administered by injection that prevented simian-HIV infection upon repeat intrarectal challenge in male macaques. We aimed to assess the safety, tolerability, and pharmacokinetics of long-acting cabotegravir injections in healthy men not at high risk of HIV-1 infection. METHODS: We did this multicentre, double-blind, randomised, placebo-controlled, phase 2a trial at ten sites in the USA...
May 22, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28546075/antimicrobial-storage-and-antibiotic-knowledge-in-the-community-a-cross-sectional-pilot-study-in-north-western-angola
#8
Joana Cortez, Edite Rosário, João E Pires, João Taborda Lopes, Moisés Francisco, Erika Vlieghe, Miguel Brito
BACKGROUND: Antimicrobials are drugs that were once lifesavers and mainly curative. Nowadays their value is increasingly under pressure because of the fast and worldwide emergence of antimicrobial resistance, which, in low resources settings, frequently occurs in microorganisms that are likely to be transmitted in the community. METHODS: A cross-sectional pilot study including 102 households within the 10th HDSS round in Dande, Bengo Province, Angola. RESULTS: From the total 102 households piloted, 77...
May 22, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28546052/status-report-from-norway-implementation-of-patient-involvement-in-norwegian-health-care
#9
Jürgen Kasper, Anne Regine Lager, Markus Rumpsfeld, Simone Kienlin, Kristine Hoel Smestad, Tone Bråthen, Holly Ankell, Tore Knutsen, Rune Kløvtveit, Pål Gulbrandsen, Per Olav Vandvik, Anja Fog Heen, Signe Flottorp, Geir Tollåli, Øystein Eiring
Norway has traditionally high standards regarding civil rights particularly emphasizing equal access to societal resources including health care. This background and the health care system's centralized national organization make it perfectly suited for implementation of shared decision making (SDM). In recent years, great efforts have been made by policy- makers, regional health authorities and not least the patients to facilitate a process of change in health communication culture. SDM is currently even given highest priority in health care strategies on all system levels...
May 22, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28546042/occluded-superficial-femoral-artery-used-for-emergency-reconstruction-a-consecutive-case-series-about-the-proper-conduit-technique
#10
M S Marsman, A Kh Jahrome, F L Moll, G G Koning
INTRODUCTION: Deep wound infections in the groin region can result in an acute or life threatening condition. Especially when there is no suitable vein available because of many reasons (e.g. previous surgery, small vessel diameter). Synthetic prosthesis sometimes are not 'first-choice-technique' because of contamination or infection. It was ad hoc hypothesized in an acute setting that a segment of an occluded Superficial Femoral Artery (SFA) could be used as a conduit in combination with eversion technique, known from carotid surgery...
May 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28545802/attitudes-towards-disorders-of-sex-development-nomenclature-among-affected-individuals
#11
Emilie K Johnson, Ilina Rosoklija, Courtney Finlayson, Diane Chen, Elizabeth B Yerkes, Mary Beth Madonna, Jane L Holl, Arlene B Baratz, Georgiann Davis, Earl Y Cheng
INTRODUCTION: Although now commonly used in medicine, the updated "disorders of sex development" (DSD) nomenclature formally introduced in 2006 has never been universally accepted by members of the affected community, particularly advocacy groups. Use of this nomenclature by medical professionals may unintentionally negatively affect access to healthcare and research for individuals with DSD conditions. OBJECTIVE: Among individuals affected by various DSD diagnoses, this study sought to (1) evaluate attitudes towards potentially controversial DSD terminology, (2) determine potential impact of terminology on how affected individuals access healthcare, and (3) explore alternate terms...
May 8, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28545610/a-case-based-reasoning-system-based-on-weighted-heterogeneous-value-distance-metric-for-breast-cancer-diagnosis
#12
Dongxiao Gu, Changyong Liang, Huimin Zhao
OBJECTIVE: We present the implementation and application of a case-based reasoning (CBR) system for breast cancer related diagnoses. By retrieving similar cases in a breast cancer decision support system, oncologists can obtain powerful information or knowledge, complementing their own experiential knowledge, in their medical decision making. METHODS: We observed two problems in applying standard CBR to this context: the abundance of different types of attributes and the difficulty in eliciting appropriate attribute weights from human experts...
March 2017: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/28545416/the-role-of-indonesian-patients-health-behaviors-in-delaying-the-diagnosis-of-nasopharyngeal-carcinoma
#13
R Fles, A C R K Bos, Supriyati, D Rachmawati, E Waliyanti, I B Tan, S M Haryana, M K Schmidt, F S T Dewi
BACKGROUND: With an estimated 13,000 newly diagnosed patients per year, nasopharyngeal carcinoma (NPC) is one of the most common types of cancer in males in Indonesia. Moreover, most patients are diagnosed at an advanced stage of the disease. This study aimed to explore the health behaviors of patients diagnosed with NPC and the possible causes of patient delay in NPC diagnosis. METHODS: A qualitative research method was used to gain better insight into patient behaviors...
May 25, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28544946/perceived-barriers-to-healthcare-and-receipt-of-recommended-medical-care-among-elderly-medicare-beneficiaries
#14
Jibby E Kurichi, Liliana Pezzin, Joel E Streim, Pui L Kwong, Ling Na, Hillary R Bogner, Dawei Xie, Sean Hennessy
PURPOSE: Many Medicare beneficiaries perceive barriers to receiving healthcare, although the consequences are unknown. Facilitators can aid in the receipt of healthcare services. The objective was to assess the relationship between perceived facilitators and barriers to healthcare and actual receipt of recommended medical care among elderly beneficiaries. METHODS: A cohort study using data from the 2001-2008 entry panels of the Medicare Current Beneficiary Survey that included 24,607 community-dwelling beneficiaries 65 years of age and older...
May 18, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28544582/evaluation-by-medical-students-of-the-educational-value-of-multi-material-and-multi-colored-three-dimensional-printed-models-of-the-upper-limb-for-anatomical-education
#15
Sreenivasulu Reddy Mogali, Wai Yee Yeong, Heang Kuan Joel Tan, Gerald Jit Shen Tan, Peter H Abrahams, Nabil Zary, Naomi Low-Beer, Michael Alan Ferenczi
For centuries, cadaveric material has been the cornerstone of anatomical education. For reasons of changes in curriculum emphasis, cost, availability, expertise, and ethical concerns, several medical schools have replaced wet cadaveric specimens with plastinated prosections, plastic models, imaging, and digital models. Discussions about the qualities and limitations of these alternative teaching resources are on-going. We hypothesize that three-dimensional printed (3DP) models can replace or indeed enhance existing resources for anatomical education...
May 19, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28544056/exploring-the-knowledge-attitudes-and-needs-of-advance-care-planning-in-older-chinese-australians
#16
S S Yap, K Chen, K M Detering, S A Fraser
AIMS AND OBJECTIVES: The purpose of this study was to identify factors that influence the engagement of Chinese-Australians with advance care planning (ACP). BACKGROUND: Despite the benefits of ACP there is a low prevalence of ACP in the Chinese-Australian community. Reasons for this are often cited as cultural considerations and taboos surrounding future medical planning and death, however, other logistical factors may also be important. DESIGN: This qualitative study used a thematic analysis grounded theory approach to explore facilitators and barriers to engagement in ACP...
May 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28543411/crowdsourcing-the-moral-limits-of-human-gene-editing
#17
Eric T Juengst
In 2015, a flourish of "alarums and excursions" by the scientific community propelled CRISPR/Cas9 and other new gene-editing techniques into public attention. At issue were two kinds of potential gene-editing experiments in humans: those making inheritable germ-line modifications and those designed to enhance human traits beyond what is necessary for health and healing. The scientific consensus seemed to be that while research to develop safe and effective human gene editing should continue, society's moral uncertainties about these two kinds of experiments needed to be better resolved before clinical trials of either type should be attempted...
May 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28542270/prevalence-of-cough-throughout-childhood-a-cohort-study
#18
Maja Jurca, Alban Ramette, Cristian M Dogaru, Myrofora Goutaki, Ben D Spycher, Philipp Latzin, Erol A Gaillard, Claudia E Kuehni
BACKGROUND: Cough in children is a common reason for medical consultations and affects quality of life. There are little population-based data on the epidemiology of recurrent cough in children and how this varies by age and sex, or between children with and without wheeze. We determined the prevalence of cough throughout childhood, comparing several standardised cough questions. We did this for the entire population and separately for girls and boys, and for children with and without wheeze...
2017: PloS One
https://www.readbyqxmd.com/read/28542027/retrospective-population-based-study-of-emergency-medical-services-attended-out-of-hospital-cardiac-arrests-in-children-in-belgium
#19
Sophie Vandeplassche, Patrick van de Voorde
OBJECTIVE: This study presents an analysis of clinical data of the circumstances and outcome of paediatric (0-16 years) out-of-hospital cardiac arrests (p-OHCA) in Belgium. METHODS: This was a retrospective study of a prospective population-based registration of physician-attended [mobile emergency group (MUG)] emergency medical services (EMS) interventions of p-OHCA in Belgium between 2010 and 2012. RESULTS: We identified 365 OHCA in 18 295 paediatric MUG interventions (2%)...
May 24, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/28541648/expert-consensus-survey-on-medication-adherence-in-psychiatric-patients-and-use-of-a-digital-medicine-system
#20
Ainslie Hatch, John P Docherty, Daniel Carpenter, Ruth Ross, Peter J Weiden
BACKGROUND: There is an unmet need to objectively assess adherence problems that are a common cause of unexplained or unexpected suboptimal outcome. A digital medicine system (DMS) has been developed to address this need in patients with serious mental illness. OBJECTIVE: To conduct a quantitative expert consensus survey to (1) assess relative importance of causes of suboptimal outcomes, (2) examine modalities used to assess adherence, (3) provide guidance on when and how to use the DMS in clinical practice once available, and (4) suggest interventions for specific reasons for nonadherence...
May 23, 2017: Journal of Clinical Psychiatry
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