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https://www.readbyqxmd.com/read/28749479/communicating-prognosis-with-parents-of-critically-ill-infants-direct-observation-of-clinician-behaviors
#1
R D Boss, M E Lemmon, R M Arnold, P K Donohue
OBJECTIVE: Delivering prognostic information to families requires clinicians to forecast an infant's illness course and future. We lack robust empirical data about how prognosis is shared and how that affects clinician-family concordance regarding infant outcomes. STUDY DESIGN: Prospective audiorecording of neonatal intensive care unit family conferences, immediately followed by parent/clinician surveys. Existing qualitative analysis frameworks were applied. RESULTS: We analyzed 19 conferences...
July 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28749364/bayesian-random-vector-functional-link-networks-for-robust-data-modeling
#2
Simone Scardapane, Dianhui Wang, Aurelio Uncini
Random vector functional-link (RVFL) networks are randomized multilayer perceptrons with a single hidden layer and a linear output layer, which can be trained by solving a linear modeling problem. In particular, they are generally trained using a closed-form solution of the (regularized) least-squares approach. This paper introduces several alternative strategies for performing full Bayesian inference (BI) of RVFL networks. Distinct from standard or classical approaches, our proposed Bayesian training algorithms allow to derive an entire probability distribution over the optimal output weights of the network, instead of a single pointwise estimate according to some given criterion (e...
July 25, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28749325/central-and-peripheral-reservoirs-of-feline-immunodeficiency-virus-in-cats-a-review
#3
Chrissy D Eckstrand, Ellen E Sparger, Brian G Murphy
Infection with feline immunodeficiency virus (FIV), a lentivirus similar to human immunodeficiency virus (HIV), results in lifelong viral persistence and progressive immunopathology in the cat. FIV has the ability to infect and produce infectious virus in a number of different cell types. FIV provirus can also be maintained in a replication-competent but transcriptionally quiescent state, facilitating viral persistence over time. Immediately after the initial infection, FIV infection quickly disseminates to many anatomical compartments within the host including lymphoid organs, gastrointestinal tract and brain...
July 28, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28749274/evaluation-of-the-i-stat-portable-clinical-analyzer-for-measurement-of-ionized-calcium-and-selected-blood-chemistry-values-in-asian-elephants-elephas-maximus
#4
Danielle K Tarbert, Erica Behling-Kelly, Heather Priest, Sara Childs-Sanford
Thei-STAT® portable clinical analyzer (PCA) provides patient-side results for hematologic, biochemical, and blood gas values when immediate results are desired. This analyzer is commonly used in nondomestic animals; however, validation of this method in comparison with traditional benchtop methods should be performed for each species. In this study, the i-STAT PCA was compared with the Radiometer ABL 800 Flex benchtop analyzer using 24 heparinized whole blood samples obtained from healthy E. maximus . In addition, the effect of sample storage was evaluated on the i-STAT PCA...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749158/a-wait-list-controlled-study-of-a-trauma-focused-cognitive-behavioral-treatment-for-intermittent-explosive-disorder-in-timor-leste
#5
Kalhari Hewage, Zachary Steel, Mohammed Mohsin, Alvin Kuowei Tay, Jose Carlos De Oliveira, Marcio Da Piedade, Natalino Tam, Derrick Silove
We tested a trauma-focused, cognitive-behavior therapy treatment (TF-CBT-anger) for intermittent explosive disorder (IED) and related dimensions of anger adapted to the local culture in postconflict Timor-Leste. The intention-to-treat sample (n = 78) comprised Timorese nationals (women = 49; men = 29), ages 18 years and older, meeting Diagnostic and Statistical Manual of Mental Disorders (4th ed.) criteria for IED, with equal numbers (n = 39 each) being randomized to the treatment group (TG) and wait-list (WL)...
July 27, 2017: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/28749116/autologous-dermal-patch-in-immediate-prosthetic-breast-reconstruction-a-case-series-report-and-comparative-analysis
#6
Annalisa Curcio, Francesco Marongiu, Federico Buggi, Giuseppe Falco, Matteo Mingozzi, Secondo Folli
No abstract text is available yet for this article.
July 26, 2017: Minerva Chirurgica
https://www.readbyqxmd.com/read/28748840/cardiovascular-involvement-in-severe-malaria-a-prospective-study-in-ranchi-jharkhand
#7
Hemant Narayan Ray, Darshit Doshi, Appu Rajan, Amit K Singh, S B Singh, M K Das
BACKGROUND & OBJECTIVES: Malaria is considered as the most important parasitic disease of humans, causing seri- ous illness that can be fatal, if not diagnosed and treated immediately. It is a multisystem disorder affecting nearly every system of the body. The aim of the present study was to evaluate the involvement of cardiovascular system in severe malaria using non-invasive methods. METHODS: This prospective study was conducted on patients of severe malaria who were admitted between June and November 2015 in the Department of Medicine, Rajendra Institute of Medical Sciences and Hospital, Ranchi, Jharkhand, India...
April 2017: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/28748832/temporo-spatial-distribution-of-insecticide-resistance-in-indian-malaria-vectors-in-the-last-quarter-century-need-for-regular-resistance-monitoring-and-management
#8
REVIEW
Kamaraju Raghavendra, Poonam Sharma Velamuri, Vaishali Verma, Natarajan Elamathi, Tapan Kumar Barik, Rajendra Mohan Bhatt, Aditya Prasad Dash
The Indian vector control programme similar to other programmes in the world is still reliant on chemical insecticides. Anopheles culicifacies is the major vector out of six primary malaria vectors in India and alone contributes about 2/3 malaria cases annually; and per se its control is actually control of malaria in India. For effective management of vectors, current information on their susceptibility status to different insecticides is essential. In this review, an attempt was made to compile and present the available data on the susceptibility status of different malaria vector species in India from the last 2...
April 2017: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/28748751/update-on-nitazoxanide-a-multifunctional-chemotherapeutic-agent
#9
Anshul Shakya, Hans Raj Bhat, Surjit Kumar Ghosh
The thiazolide nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that adversely affects viability, growth, and proliferation of a range of extracellular and intracellular protozoan, helminths, anaerobic and microaerophilic bacteria, and viruses. Current review compiled the potential chemotherapeutic efficacy of NTZ against a variety of such disease-causing macro and/or micro-organisms as well as neoplastic cells. The most accepted anti-infective mechanism of NTZ involves impairment of the energy metabolism in anaerobic pathogens by inhibition of the pyruvate: ferredoxin/flavodoxin oxidoreductase (PFOR)...
July 27, 2017: Current Drug Discovery Technologies
https://www.readbyqxmd.com/read/28748586/legal-termination-of-pregnancy-as-an-opportunity-for-expanding-postabortion-contraception-experience-at-the-pereira-rossell-hospital-montevideo-uruguay
#10
Fernanda Nozar, Diego Greif, Francisco Coppola, Verónica Fiol, Leonel Briozzo
OBJECTIVE: To determine to what extent women adopted highly effective contraceptive methods after a legal abortion. METHODS: The data available during a period before and another period after liberalization of the abortion law were reviewed. The data gathering was incomplete and reliable only during certain periods, which were used in the study. RESULTS: There was an increase in the proportion of women who returned for contraception and in the proportion who used any method and long-acting methods; however, no contraception was administered immediately after abortion and only 16% of all women treated started to use a long-acting method during the period after the law was liberalized...
August 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28748395/variation-in-caries-treatment-proposals-among-dentists-in-norway-the-best-interest-of-the-child
#11
A Rønneberg, A B Skaare, B Hofmann, I Espelid
AIM: To explore variation in treatment-related-decisions for severe caries in children among dentists in the Public Dental Service (PDS) in Norway. It was also to evaluate the treatment choices in relation to the best interest of children and a child's rights to enjoy the highest standard of health care. METHODS: A pre-coded questionnaire was sent electronically to all general dental practitioners (GDPs) working in the PDS in eight counties in Norway (n = 611)...
July 26, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28748311/advantages-of-melodic-over-rhythmic-movement-sonification-in-bimanual-motor-skill-learning
#12
J F Dyer, P Stapleton, M W M Rodger
An important question for skill acquisition is whether and how augmented feedback can be designed to improve the learning of complex skills. Auditory information triggered by learners' actions, movement sonification, can enhance learning of a complex bimanual coordination skill, specifically polyrhythmic bimanual shape tracing. However, it is not clear whether the coordination of polyrhythmic sequenced movements is enhanced by auditory-specified timing information alone or whether more complex sound mappings, such as melodic sonification, are necessary...
July 26, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28748152/cardiovascular-diagnosis-and-therapy-cdt-editorial-the-minimalist-immediate-mechanical-intervention-study
#13
EDITORIAL
Muhammad Aetesam-Ur-Rahman, Colin Berry
No abstract text is available yet for this article.
June 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28748101/evaluation-of-a-hockey-deceased-organ-donation-awareness-campaign-a-population-based-cohort-study
#14
Kyla L Naylor, Susan McKenzie, Cindy Cherry, Eric McArthur, Alvin H Li, Megan K McCallum, S Joseph Kim, Versha Prakash, Gregory A Knoll, Amit X Garg
BACKGROUND: The Kidney Foundation of Canada developed a pilot campaign to educate persons attending junior hockey league games in London, Ontario, Canada, on deceased organ donation. OBJECTIVE: To evaluate the impact of a hockey campaign on the number of new organ and tissue donor registrants. DESIGN: Population-based retrospective cohort study. SETTING: Residents of London, Ontario. PATIENTS: We included 255 476 individuals eligible to register for organ donation with a London, Ontario postal code...
2017: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/28748047/immediate-vs-delayed-endosseous-integration-of-maxi-implants-a-torque-removal-animal-study
#15
Hanif Allahbakhshi, Fariborz Vafaee, Mehrdad Lotfazar, Ahmad Hasan Ahangary, Masoumeh Khoshhal, Farnoush Fotovat
Background. Delayed loading is one of the concerns in implant patients. Immediate loading can solve the problem and make patients more satisfied. The present study aimed to compare the removal torque of maxi implants under different loading (immediate and delayed) patterns. Methods. This split-mouth experimental study included 2 dogs. Impressions were made and then all the premolars were extracted under general anesthesia. After a three-month healing period, 3 implants were inserted in each quadrant (a total of 12 implants)...
2017: Journal of Dental Research, Dental Clinics, Dental Prospects
https://www.readbyqxmd.com/read/28747995/assessment-of-inhibitory-effects-on-major-human-cytochrome-p450-enzymes-by-spasmolytics-used-in-the-treatment-of-overactive-bladder-syndrome
#16
Dominik Dahlinger, Sevinc Aslan, Markus Pietsch, Sebastian Frechen, Uwe Fuhr
BACKGROUND: The objective of this study was to examine the inhibitory potential of darifenacin, fesoterodine, oxybutynin, propiverine, solifenacin, tolterodine and trospium chloride on the seven major human cytochrome P450 enzymes (CYP) by using a standardized and validated seven-in-one cytochrome P450 cocktail inhibition assay. METHODS: An in vitro cocktail of seven highly selective probe substrates was incubated with human liver microsomes and varying concentrations of the seven test compounds...
July 2017: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/28747896/time-dependent-effects-of-acute-exercise-on-university-students-cognitive-performance-in-temperate-and-cold-environments
#17
Ling-Yu Ji, Xiao-Ling Li, Yang Liu, Xiu-Wen Sun, Hui-Fen Wang, Long Chen, Liang Gao
Background: Few studies have examined the acute exercise-induced changes in cognitive performance in different thermal environments and the time course effects. Objective: Investigate the time-dependent effects of acute exercise on university students' processing speed, working memory and cognitive flexibility in temperate and cold environments. Method: Twenty male university students (age 23.5 ± 2.0 years) with moderate physical activity level participated in a repeated-measures within-subjects design. Processing speed, working memory and cognitive flexibility were assessed using CogState test battery at baseline (BASE), followed by a 45-min rest (REST), immediately after (EX) and 30 min after (POST-EX) 30-min moderate-intensity treadmill running in both temperate (TEMP; 25°C) and cold (COLD; 10°C) environments...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28747888/the-hsp72-and-hsp90%C3%AE-mrna-responses-to-hot-downhill-running-are-reduced-following-a-prior-bout-of-hot-downhill-running-and-occur-concurrently-within-leukocytes-and-the-vastus-lateralis
#18
James A Tuttle, Bryna C R Chrismas, Oliver R Gibson, James H Barrington, David C Hughes, Paul C Castle, Alan J Metcalfe, Adrian W Midgley, Oliver Pearce, Chindu Kabir, Faizal Rayanmarakar, Sami Al-Ali, Mark P Lewis, Lee Taylor
The leukocyte heat shock response (HSR) is used to determine individual's thermotolerance. The HSR and thermotolerance are enhanced following interventions such as preconditioning and/or acclimation/acclimatization. However, it is unclear whether the leukocyte HSR is an appropriate surrogate for the HSR in other tissues implicated within the pathophysiology of exertional heat illnesses (e.g., skeletal muscle), and whether an acute preconditioning strategy (e.g., downhill running) can improve subsequent thermotolerance...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28747761/bmp2-modified-injectable-hydrogel-for-osteogenic-differentiation-of-human-periodontal-ligament-stem-cells
#19
Seung Hun Park, Jin Seon Kwon, Byeong Sung Lee, Ji Hoon Park, Bo Keun Lee, Jeong-Ho Yun, Bun Yeoul Lee, Jae Ho Kim, Byoung Hyun Min, Tae Hyeon Yoo, Moon Suk Kim
This is the first report on the development of a covalently bone morphogenetic protein-2 (BMP2)-immobilized hydrogel that is suitable for osteogenic differentiation of human periodontal ligament stem cells (hPLSCs). O-propargyl-tyrosine (OpgY) was site-specifically incorporated into BMP2 to prepare BMP2-OpgY with an alkyne group. The engineered BMP2-OpgY exhibited osteogenic characteristics after in vitro osteogenic differentiation of hPLSCs, indicating the osteogenic ability of BMP2-OpgY. A methoxy polyethylene glycol-(polycaprolactone-(N3)) block copolymer (MC-N3) was prepared as an injectable in situ-forming hydrogel...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747726/association-of-micrornas-with-argonaute-proteins-in-the-malaria-mosquito-anopheles-gambiae-after-blood-ingestion
#20
Xiaonan Fu, George Dimopoulos, Jinsong Zhu
Drastic changes in gene expression occur after adult female mosquitoes take a blood meal and use the nutrients for egg maturation. A growing body of evidence indicates that microRNAs (miRNAs) contribute to this tightly controlled tissue- and stage-specific gene expression. To investigate the role of miRNAs, we monitored miRNA expression in the mosquito Anopheles gambiae during the 72-h period immediately after blood feeding. We also measured the association of miRNAs with Argonaute 1 (Ago1) and Argonaute 2 (Ago2) to assess the functional status of individual miRNA species...
July 26, 2017: Scientific Reports
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