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https://www.readbyqxmd.com/read/29765868/retrobulbar-steatitis-and-meningitis-empyema-secondary-to-right-otitis-media-right-otitis-interna-and-an-inflammatory-polyp-in-a-cat
#1
Elena Fenollosa-Romero, Olivier Taeymans, Pieter Nelissen, Giunio B Cherubini, Claudia Busse
The purpose was to describe a case of retrobulbar steatitis and meningitis in a cat caused by otitis media, otitis interna and an inflammatory polyp in the middle ear. Investigations included ophthalmic and neurological examinations, haematology and biochemistry, magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) analysis and aerobic, anaerobic bacterial and fungal culture of material from the middle ear. A 6-year-old female neutered domestic-short-haired cat presented with right-sided exophthalmos and resistance to retropulsion...
2018: Open Veterinary Journal
https://www.readbyqxmd.com/read/29737739/-preliminary-study-of-dti-on-cerebral-white-matter-micro-structure-of-patients-with-idiopathic-olfactory-loss
#2
Lin Yin Yao, Yi Chen Guo, Xiao Jun Zhan, Zhi Fu Sun, Ying Li, Yong Xiang Wei
OBJECTIVES: To investigate the cerebral white matter micro-structure in patients with idiopathic olfactory loss using diffusion tensor imaging (DTI). METHODS: Sixteen patients with idiopathic olfactory loss and sixteen normal subjects matched by age and sex were recruited in this study. Sniffin'Stick olfactory test was performed to evaluate the olfactory function of all subjects. We acquired diffusion tensor images with an echo planar imaging (EPI) sequence from all subject on a 3T scanner...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29733071/symmetrical-and-bilateral-basal-ganglia-calcification-case-series-and-literature-review
#3
Amado Jiménez-Ruiz, Omar Cárdenas-Sáenz, José Luis Ruiz-Sandoval
Introduction: Symmetric, bilateral basal ganglia calcification is rare finding that sometimes occurs asymptomatically. Its prevalence increases with age, and the most affected site is the globus pallidus. Report of cases: A series of seven cases with clinical and imaging diagnosis of basal ganglia calcification, recorded during the 2012 to 2016 period at the Department of Internal Medicine of the Hospital Civil de Guadalajara "Fray Antonio Alcalde, is presented...
2018: Gaceta Médica de México
https://www.readbyqxmd.com/read/29731294/derivation-and-validation-of-a-predictive-model-for-the-readmission-of-patients-with-diabetes-mellitus-treated-in-internal-medicine-departments
#4
J Ena, R Gómez-Huelgas, B C Gracia-Tello, P Vázquez-Rodríguez, J N Alcalá-Pedrajas, F J Carrasco-Sánchez, B Murcia-Casas, M Romero-Sánchez, J V Segura-Heras, J Carretero
OBJECTIVES: We developed a predictive model for the hospital readmission of patients with diabetes. The objective was to identify the frail population that requires additional strategies to prevent readmissions at 90 days. METHODS: Using data collected from 1977 patients in 3 studies on the national prevalence of diabetes (2015-2017), we developed and validated a predictive model of readmission at 90 days for patients with diabetes. RESULTS: A total of 704 (36%) readmissions were recorded...
May 4, 2018: Revista Clínica Española
https://www.readbyqxmd.com/read/29705556/deep-brain-stimulation-parameters-for-dystonia-a-systematic-review
#5
REVIEW
Philippe Magown, Rafael A Andrade, Alexandra Soroceanu, Zelma H T Kiss
INTRODUCTION: Programming of globus pallidus pars interna (GPi) deep brain stimulation (DBS) systems for dystonia is complex because clinical benefits are often gradual. Some groups have advocated starting DBS with higher electrical parameters, whereas others have suggested the opposite. This variability in programming, even within each dystonia subtype, makes it challenging to compare outcomes and program the generators. To determine how variable DBS for dystonia stimulation parameters are, we performed a systematic literature review...
April 17, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29703392/analysis-of-the-activity-of-interconsultations-conducted-by-the-departments-of-internal-medicine-reina-semi-study-registry-of-interconsultations-and-shared-care-of-the-spanish-society-of-internal-medicine
#6
R Monte-Secades, E Montero-Ruiz, J Feyjoo-Casero, M González-Anglada, M Freire-Romero, A Gil-Díaz, A Granados-Maturano, D Rubal-Bran, R Rabuñal-Rey, L Nevado Lopez-Alegria
OBJECTIVE: To analyse the activity of interconsultations conducted by internal medicine (IM) departments, their formal aspects and the profile of clinical care required and to quantify the workload they represent. MATERIAL AND METHOD: A multicentre, observational prospective study was conducted with consecutive hospitalised patients treated by IM departments using interconsultations between May 15 and June 15, 2016. We estimated the workload related to this activity (1time unit [TU]=10min)...
April 24, 2018: Revista Clínica Española
https://www.readbyqxmd.com/read/29690315/caridean-prawn-crustacea-decapoda-from-dong-ao-island-guangdong-china
#7
Qing-Hua Chen, Wen-Jian Chen, Zhao-Liang Guo
The present study, based on a faunistic and ecological survey of caridean shrimps from Dong'ao Island, Guangdong Province, expands the knowledge of morphology, colouration, and distribution of three species, two of which belong to genus Caridina and one belong to genus Marcrobrachium. Caridina zhujiangensis, new species is distinguished from the closely related species C. typus H. Miline Edwars,1837 by shorter rostrum and with only one ventral margin teeth, the shape of the endopod of the first male pleopod and the appendix interna arising from distal 1/3 of endopod...
March 21, 2018: Zootaxa
https://www.readbyqxmd.com/read/29674778/-un-processo-che-pu%C3%A3-gettare-luce-sulla-cosiddetta-paura-di-s%C3%A3-nel-disturbo-ossessivo-compulsivo-l-identificazione-retrospettiva-delle-motivazioni-e-delle-inclinazioni
#8
Gherardo Mannino, Rossella Guerini
RIASSUNTO. Al fine di comprendere meglio la psicopatologia del disturbo ossessivo-compulsivo (DOC), in anni recenti è stata prestata una crescente attenzione alla cosiddetta "paura di sé" (fear of self), vale a dire la paura che le persone con DOC nutrono di ospitare dentro di sé aspetti inaccettabili. Tuttavia, l'esatta dinamica di questo fenomeno ancora non è chiara: di conseguenza, allo scopo di delucidarla meglio, sarà qui descritto uno specifico processo psicologico denominato Identificazione Retrospettiva delle Motivazioni e delle Inclinazioni (IRMI)...
March 2018: Rivista di Psichiatria
https://www.readbyqxmd.com/read/29671179/clinical-infection-in-house-rats-rattus-rattus-caused-by-streptobacillus-notomytis
#9
Viktoria Michel, Claudia Ulber, Dietrich Pöhle, Beate Köpke, Katharina Engel, Ute Kaim, Ahmad Fawzy, Sophie Funk, Juliane Fornefett, Christoph Georg Baums, Tobias Eisenberg
Rat bite fever is an under-reported, under-diagnosed emerging zoonosis with worldwide distribution. Besides Spirillum minus, Streptobacillus moniliformis is the major causative microorganism although it usually colonises rats without any clinical signs. A group of house rats (Rattus rattus) kept in a zoo exhibition for educational purposes suffered from neurological signs including disorientation, torticollis, stall walking, ataxia and death. Gross pathological and histo-pathological examinations of the investigated rats revealed high-grade otitis interna et media, from which Streptobacillus notomytis was isolated in pure culture or as the predominant microorganism...
April 18, 2018: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29667535/clinical-features-and-short-term-outcome-of-presumptive-intracranial-complications-associated-with-otitis-media-interna-a-multi-center-retrospective-study-of-19-cats-2009-2017
#10
Sarah A Moore, R Timothy Bentley, Sheila Carrera-Justiz, Kari D Foss, Ronaldo C da Costa, Laurie B Cook
Objectives The aim of this study was to compile an overview of the clinical features of intracranial complication of otitis media/interna (OMI) in cats managed across five veterinary referral hospitals. Of additional interest were culture results that could inform empirical antibiotic selection, as well as outcome with both medical and surgical management. Methods A retrospective medical record review was conducted at five veterinary referral practices to identify cats with a diagnosis of intracranial complication secondary to OMI between 2009 and 2017...
April 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29650358/prognostic-relevance-of-glomerular-filtration-rate-estimation-obtained-through-different-equations-in-hospitalized-elderly-patients
#11
Paolo Gallo, Antonio De Vincentis, Claudio Pedone, Alessandro Nobili, Mauro Tettamanti, Umberto Vespasiani Gentilucci, Antonio Picardi, Pier Mannuccio Mannucci, Raffaele Antonelli Incalzi
The estimated glomerular filtration rate (eGFR) is a predictor of important outcomes and its reduction has been associated with the risk of all-cause mortality in both general population and elderly patients. However while reduced renal function is common in older people, the best method for estimating GFR remains unclear, especially in an acute care setting. Most studies analyzing the accuracy of eGFR in the elderly were carried out in different heterogeneous settings. In this study, we compare the prognostic value of different formulas estimating GFR in predicting the risk of in-hospital morbidity and mortality within 3 months from discharge in elderly hospitalized patients...
April 9, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29621230/conditional-mouse-models-support-the-role-of-slc39a14-zip14-in-hyperostosis-cranialis-interna-and-in-bone-homeostasis
#12
Gretl Hendrickx, Vere M Borra, Ellen Steenackers, Timur A Yorgan, Christophe Hermans, Eveline Boudin, Jérôme J Waterval, Ineke D C Jansen, Tolunay Beker Aydemir, Niels Kamerling, Geert J Behets, Christine Plumeyer, Patrick C D'Haese, Björn Busse, Vincent Everts, Martin Lammens, Geert Mortier, Robert J Cousins, Thorsten Schinke, Robert J Stokroos, Johannes J Manni, Wim Van Hul
Hyperostosis Cranialis Interna (HCI) is a rare bone disorder characterized by progressive intracranial bone overgrowth at the skull. Here we identified by whole-exome sequencing a dominant mutation (L441R) in SLC39A14 (ZIP14). We show that L441R ZIP14 is no longer trafficked towards the plasma membrane and excessively accumulates intracellular zinc, resulting in hyper-activation of cAMP-CREB and NFAT signaling. Conditional knock-in mice overexpressing L438R Zip14 in osteoblasts have a severe skeletal phenotype marked by a drastic increase in cortical thickness due to an enhanced endosteal bone formation, resembling the underlying pathology in HCI patients...
April 5, 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29609042/the-primate-fovea-structure-function-and-development
#13
REVIEW
Andreas Bringmann, Steffen Syrbe, Katja Görner, Johannes Kacza, Mike Francke, Peter Wiedemann, Andreas Reichenbach
A fovea is a pitted invagination in the inner retinal tissue (fovea interna) that overlies an area of photoreceptors specialized for high acuity vision (fovea externa). Although the shape of the vertebrate fovea varies considerably among the species, there are two basic types. The retina of many predatory fish, reptilians, and birds possess one (or two) convexiclivate fovea(s), while the retina of higher primates contains a concaviclivate fovea. By refraction of the incoming light, the convexiclivate fovea may function as image enlarger, focus indicator, and movement detector...
March 30, 2018: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/29608802/king-s-parkinson-s-disease-pain-scale-for-assessment-of-pain-relief-following-deep-brain-stimulation-for-parkinson-s-disease
#14
Marisa DiMarzio, Julie G Pilitsis, Lucy Gee, Sophia Peng, Julia Prusik, Jennifer Durphy, Adolfo Ramirez-Zamora, Era Hanspal, Eric Molho, Sarah E McCallum
OBJECTIVE: Pain is a prevalent and debilitating nonmotor symptom of Parkinson's disease (PD) that is often inadequately managed. Deep brain stimulation (DBS) has been shown to relieve pain in PD but an effective method of identifying which types of PD pain respond to DBS has not been established. We examine the effects of DBS on different types of PD pain using the King's Parkinson's disease pain scale (KPDPS), the only validated scale of PD pain. METHODS: We prospectively followed 18 PD patients undergoing subthalamic nucleus (STN) or Globus pallidus interna (GPi) DBS...
April 2, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29602447/use-of-tocilizumab-in-systemic-sclerosis-a-brief-literature-review
#15
A Fernández-Codina, J Fernández-Fernández, A Fernández-Pantiga
The available treatments for systemic sclerosis (SS) have limited effectiveness. Treatment with tocilizumab (TCZ), a biological drug that inhibits interleukin 6 (IL-6), has recently been proposed. In this study, we conducted a literature review to assess the safety and efficacy of TCZ in SS. We found 52 articles, 10 of which we selected after evaluating the articles. In a randomised clinical trial, TCZ showed a nonsignificant improvement in the degree of skin induration, while another observational study showed neutral results...
March 27, 2018: Revista Clínica Española
https://www.readbyqxmd.com/read/29572280/beta-oscillations-and-urinary-voiding-in-parkinson-disease
#16
Holly A Roy, Tipu Z Aziz, James J Fitzgerald, Alexander L Green
OBJECTIVES: To investigate the role of beta oscillations in urinary voiding and their association with lower urinary tract symptoms in Parkinson disease (PD). METHODS: We used surgically implanted deep brain stimulation electrodes to record local field potential signals from the subthalamic nucleus (STN) and globus pallidus interna (GPi) of patients with PD during urinary voiding. Five patients with STN electrodes and 5 patients with GPi electrodes were tested. We also explored correlations between beta oscillatory power and urinary symptoms assessed by the International Consultation on Incontinence Lower Urinary Tract Symptoms questionnaire...
March 23, 2018: Neurology
https://www.readbyqxmd.com/read/29559384/region-specific-expression-of-nmda-receptor-glun2c-subunit-in-parvalbumin-positive-neurons-and-astrocytes-analysis-of-glun2c-expression-using-a-novel-reporter-model
#17
Aparna Ravikrishnan, Pauravi J Gandhi, Gajanan P Shelkar, Jinxu Liu, Ratnamala Pavuluri, Shashank M Dravid
Hypofunction of NMDA receptors in parvalbumin (PV)-positive interneurons has been proposed as a potential mechanism for cortical abnormalities and symptoms in schizophrenia. GluN2C-containing receptors have been linked to this hypothesis due to the higher affinity of psychotomimetic doses of ketamine for GluN1/2C receptors. However, the precise cell-type expression of GluN2C subunit remains unknown. We describe the expression of the GluN2C subunit using a novel EGFP reporter model. We observed EGFP(GluN2C) localization in PV-positive neurons in the nucleus reticularis of the thalamus, globus pallidus externa and interna, ventral pallidum and substantia nigra...
March 17, 2018: Neuroscience
https://www.readbyqxmd.com/read/29550492/histology-confirms-that-macroscopic-evaluation-of-ovaries-is-a-valid-method-for-the-assessment-of-the-reproductive-status-in-wild-boar
#18
Friederike Gethöffer, Christiane Pfarrer, Ursula Siebert
Research on reproduction and fertility is an essential fundament of management strategies in European wild boar. Concerning the examination of the reproductive tract, methods still lack conformity and comparability. So far the reproductive status of female wild boar has been assessed by ovarian macroscopic examination. In order to find out if this is a valid method, 21 ovaries of 8-34 months old animals covering (early) follicular phase and cyclic inactivity were evaluated microscopically. Number and dimension of follicles as well as the occurrence of atretic follicles were compared and related to age, weight, ovary weight and size of ovary...
March 2, 2018: Theriogenology
https://www.readbyqxmd.com/read/29544766/molecular-characterization-expression-and-cellular-localization-of-cyp17-gene-during-geese-anser-cygnoides-follicular-development
#19
Huilan Huang, Da Chen, Shenqiang Hu, Jiwen Wang, Hehe Liu, Jiwei Hu, Liang Li
As a key member of the cytochrome P450 gene superfamily, CYP17 gene encodes 17α-hydroxylase/C17,20-lyase that is critical for directing androgen synthesis. The CYP17 gene has been identified in several species, yet little is known about its distribution and expression profile during goose follicular development. In the present study, we obtained the full-length coding sequence of goose CYP17 (gCYP17) gene for the first time using RACE method. Its sequence alignment and phylogenetic analysis suggested that gCYP17 was highly conserved with those of other birds and consisted of four main functional domains like other species...
June 5, 2018: Gene
https://www.readbyqxmd.com/read/29531607/successful-craniotomy-for-advanced-basal-cell-carcinomas-with-cranial-bone-invasion-and-dura-mater-infiltration-unique-presentation-in-a-bulgarian-patient
#20
Slavomir Kondoff, Atanas Drenchev, Torello Lotti, Uwe Wollina, Ilia Lozev, Ivan Pidakev, Ivan Terziev, Yavor Grigorov, Serena Gianfaldoni, Georgi Tchernev
BACKGROUND: Basal cell carcinomas (BCC) located in the sun-exposed regions are a serious therapeutic challenge. Therefore early diagnosis and adequate therapy should be of a high priority for every dermatologic surgeon. CASE PRESENTATION: We are presenting a patient with multiple BCCs, located on the area of the scalp, who had been treated several years ago with electrocautery and curettage after histopathological verification. However, the last few years the tumours have advanced, infiltrating firstly the tabula external and a year later the tabula interna of the cranium...
February 15, 2018: Open Access Macedonian Journal of Medical Sciences
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