keyword
MENU ▼
Read by QxMD icon Read
search

john walkup

keyword
https://www.readbyqxmd.com/read/28448176/child-and-adolescent-adherence-with-cognitive-behavioral-therapy-for-anxiety-predictors-and-associations-with-outcomes
#1
Phyllis Lee, Asima Zehgeer, Golda S Ginsburg, James McCracken, Courtney Keeton, Philip C Kendall, Boris Birmaher, Dara Sakolsky, John Walkup, Tara Peris, Anne Marie Albano, Scott Compton
Cognitive behavioral therapy (CBT) for anxiety disorders is effective, but nonadherence with treatment may reduce the benefits of CBT. This study examined (a) four baseline domains (i.e., demographic, youth clinical characteristics, therapy related, family/parent factors) as predictors of youth adherence with treatment and (b) the associations between youth adherence and treatment outcomes. Data were from 279 youth (7-17 years of age, 51.6% female; 79.6% White, 9% African American), with Diagnostic and Statistical Manual of Mental Disorders (4th ed...
April 27, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28423149/transdiagnostic-behavioral-therapies-in-pediatric-primary-care-looking-ahead
#2
John T Walkup, Tara Mathews, Cori Meredith Green
No abstract text is available yet for this article.
April 19, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28384010/placebo-response-in-pediatric-anxiety-disorders-results-from-the-child-adolescent-anxiety-multimodal-study
#3
Jeffrey R Strawn, Eric T Dobson, Jeffrey A Mills, Gary J Cornwall, Dara Sakolsky, Boris Birmaher, Scott N Compton, John Piacentini, James T McCracken, Golda S Ginsburg, Phillip C Kendall, John T Walkup, Anne Marie Albano, Moira A Rynn
OBJECTIVES: The aim of this study is to identify predictors of pill placebo response and to characterize the temporal course of pill placebo response in anxious youth. METHODS: Data from placebo-treated patients (N = 76) in the Child/Adolescent Anxiety Multimodal Study (CAMS), a multisite, randomized controlled trial that examined the efficacy of cognitive-behavioral therapy, sertraline, their combination, and placebo for the treatment of separation, generalized, and social anxiety disorders, were evaluated...
April 6, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28278599/mediators-of-treatment-outcomes-for-anxious-children-and-adolescents-the-role-of-somatic-symptoms
#4
Amy E Hale, Golda S Ginsburg, Grace Chan, Philip C Kendall, James T McCracken, Dara Sakolsky, Boris Birmaher, Scott N Compton, Anne Marie Albano, John T Walkup
Cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitors are effective treatments for pediatric anxiety disorders. However, the mechanisms of these treatments are unknown. Previous research indicated that somatic symptoms are reduced following treatment, but it is unclear if their reductions are merely a consequence of treatment gains. This study examined reductions in somatic symptoms as a potential mediator of the relationship between treatment and anxiety outcomes. Participants were 488 anxious youth ages 7-17 (M = 10...
February 26, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28253735/antidepressant-efficacy-for-depression-in-children-and-adolescents-industry-and-nimh-funded-studies
#5
John T Walkup
Significant controversy surrounds the efficacy of the newer antidepressants for children and adolescents with depression. The controversy largely hinges on meta-analyses of studies that suggest that antidepressants are minimally effective, not effective, or equivalent to placebo. In this review, the author discusses several scientific and clinical complexities that are important to understand in reviewing the antidepressant literature: the strengths and weaknesses of meta-analyses; the scientific and regulatory context for the large number of antidepressant trials in the late 1990s and early 2000s; and the distinction between a negative trial, where the treatment does not demonstrate efficacy, and a failed trial, where methodological problems make it impossible to draw any conclusion about efficacy...
March 3, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28202705/moderators-and-predictors-of-response-to-behavior-therapy-for-tics-in-tourette-syndrome
#6
Denis G Sukhodolsky, Douglas W Woods, John Piacentini, Sabine Wilhelm, Alan L Peterson, Lily Katsovich, James Dziura, John T Walkup, Lawrence Scahill
OBJECTIVE: To examine moderators and predictors of response to behavior therapy for tics in children and adults with Tourette syndrome and chronic tic disorders. METHODS: Data from 2 10-week, multisite studies (1 in children and 1 in adults; total n = 248) comparing comprehensive behavioral intervention for tics (CBIT) to psychoeducation and supportive therapy (PST) were combined for moderator analyses. Participants (177 male, 71 female) had a mean age of 21.5 ± 13...
March 14, 2017: Neurology
https://www.readbyqxmd.com/read/28199072/genetic-risk-score-analysis-in-early-onset-bipolar-disorder
#7
Paul E Croarkin, Joan L Luby, Kelly Cercy, Jennifer R Geske, Marin Veldic, Matthew Simonson, Paramjit T Joshi, Karen Dineen Wagner, John T Walkup, Malik M Nassan, Alfredo B Cuellar-Barboza, Leah Casuto, Susan L McElroy, Peter S Jensen, Mark A Frye, Joanna M Biernacka
OBJECTIVE: In this study, we performed a candidate genetic risk score (GRS) analysis of early-onset bipolar disorder (BD). METHODS: Treatment of Early Age Mania (TEAM) study enrollment and sample collection took place from 2003 to 2008. Mayo Clinic Bipolar Biobank samples were collected from 2009 to 2013. Genotyping and analyses for the present study took place from 2013 to 2014. The diagnosis of BD was based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision criteria...
February 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27882443/gut-microbiota-and-autism-key-concepts-and-findings
#8
Helen T Ding, Ying Taur, John T Walkup
There is an emerging body of evidence linking the intestinal microbiota with autism spectrum disorders (ASD). Studies have demonstrated differences in the composition of gut bacteria between children with ASD and controls. Certain intestinal bacteria have been observed in abundance and may be involved in the pathogenesis of ASD; including members of the Clostridium and Sutterella genus. Evidence from animal models suggest that certain microbial shifts in the gut may produce changes consistent with the clinical picture of autism, with proposed mechanisms including toxin production, aberrations in fermentation processes/products, and immunological and metabolic abnormalities...
November 24, 2016: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/27864156/neurocognitive-predictors-of-treatment-response-to-randomized-treatment-in-adults-with-tic-disorders
#9
Amitai Abramovitch, Lauren S Hallion, Hannah E Reese, Douglas W Woods, Alan Peterson, John T Walkup, John Piacentini, Lawrence Scahill, Thilo Deckersbach, Sabine Wilhelm
Tourette's disorder (TS) and chronic tic disorder (CTD) are neurodevelopmental disorders characterized by involuntary vocal and motor tics. Consequently, TS/CTD have been conceptualized as disorders of cognitive and motor inhibitory control. However, most neurocognitive studies have found comparable or superior inhibitory capacity among individuals with TS/CTD relative to healthy controls. These findings have led to the hypothesis that individuals with TS/CTD develop increased inhibitory control due to the constant need to inhibit tics...
March 6, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/27736202/decreases-in-suicide-deaths-and-attempts-linked-to-the-white-mountain-apache-suicide-surveillance-and-prevention-system-2001-2012
#10
Mary F Cwik, Lauren Tingey, Alexandra Maschino, Novalene Goklish, Francene Larzelere-Hinton, John Walkup, Allison Barlow
OBJECTIVES: We evaluated the impact of a comprehensive, multitiered youth suicide prevention program among the White Mountain Apache of Arizona since its implementation in 2006. METHODS: Using data from the tribally mandated Celebrating Life surveillance system, we compared the rates, numbers, and characteristics of suicide deaths and attempts from 2007 to 2012 with those from 2001 to 2006. RESULTS: The overall Apache suicide death rates dropped from 40...
October 13, 2016: American Journal of Public Health
https://www.readbyqxmd.com/read/27492388/feasibility-tolerability-and-safety-of-pediatric-hyperpolarized-129-xe-magnetic-resonance-imaging-in-healthy-volunteers-and-children-with-cystic-fibrosis
#11
Laura L Walkup, Robert P Thomen, Teckla G Akinyi, Erin Watters, Kai Ruppert, John P Clancy, Jason C Woods, Zackary I Cleveland
BACKGROUND: Hyperpolarized (129)Xe is a promising contrast agent for MRI of pediatric lung function, but its safety and tolerability in children have not been rigorously assessed. OBJECTIVE: To assess the feasibility, safety and tolerability of hyperpolarized (129)Xe gas as an inhaled contrast agent for pediatric pulmonary MRI in healthy control subjects and in children with cystic fibrosis. MATERIALS AND METHODS: Seventeen healthy control subjects (ages 6-15 years, 11 boys) and 11 children with cystic fibrosis (ages 8-16 years, 4 boys) underwent (129)Xe MRI, receiving up to three doses of (129)Xe gas prepared by either a commercially available or a homebuilt (129)Xe polarizer...
November 2016: Pediatric Radiology
https://www.readbyqxmd.com/read/27477942/hyperpolarized-129-xe-for-investigation-of-mild-cystic-fibrosis-lung-disease-in-pediatric-patients
#12
Robert P Thomen, Laura L Walkup, David J Roach, Zackary I Cleveland, John P Clancy, Jason C Woods
BACKGROUND: Cystic fibrosis (CF) is a genetic disease which carries high morbidity and mortality from lung-function decline. Monitoring disease progression and treatment response in young patients is desirable, but serial imaging via CT is often considered prohibitive, and detailed functional information cannot be obtained using conventional imaging techniques. Hyperpolarized (129)Xe magnetic resonance imaging (MRI) can depict and quantify regional ventilation, but has not been investigated in pediatrics...
March 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/27456111/temperamental-characteristics-of-withdrawn-behavior-problems-in-children
#13
David H Rubin, Eileen T Crehan, Robert R Althoff, David C Rettew, Erica Krist, Valerie Harder, John T Walkup, James J Hudziak
Withdrawn/depressed behavior (WD) as defined by the Child Behavior Checklist (CBCL) relates to various outcomes in developmental psychopathology such as depression, pervasive developmental disorders, and suicide. We sought to examine the temperamental characteristics of children who concurrently endorse symptoms of WD. Junior Temperament and Characteristic Inventory (JTCI) and CBCL data were collected from 397 children's parents in a family study in the northeastern United States. Linear mixed models were used to test the relations between WD and temperament dimensions (Novelty Seeking, Harm Avoidance, Reward Dependence, Persistence) on the JTCI, while controlling for age, sex, item overlap, and co-occurring aggression and attention problems...
June 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/27110050/relationships-between-premonitory-urge-and-anxiety-in-youth-with-chronic-tic-disorders
#14
Michelle Rozenman, Olivia E Johnson, Susanna W Chang, Douglas W Woods, John T Walkup, Sabine Wilhelm, Alan Peterson, Lawrence Scahill, John Piacentini
Tourette's Disorder and other chronic tic disorders are common neurodevelopmental conditions. One characteristic of tic disorders is the premonitory urge, an aversive or unpleasant sensory phenomenon that may precede tics. Initial examination of premonitory urge in pediatric tic disorders suggests that awareness and experience of sensations preceding tics may be related to anxiety and OCD. However, it may be possible that specific anxiety-related symptoms, such as anxious physiologic arousal, are particularly relevant to the experience of premonitory urge...
July 1, 2015: Children's Health Care: Journal of the Association for the Care of Children's Health
https://www.readbyqxmd.com/read/26938709/review-of-trichotillomania-skin-picking-and-other-body-focused-repetitive-behaviors-by-jon-e-grant-dan-j-stein-douglas-w-woods-and-nancy-j-keuthen
#15
Shannon M Bennett, John T Walkup
No abstract text is available yet for this article.
March 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/26855465/clinical-correlates-and-predictors-of-caregiver-strain-in-children-with-chronic-tic-disorders
#16
Krishnapriya Ramanujam, Michael B Himle, Loran P Hayes, Douglas W Woods, Lawrence Scahill, Denis G Sukhodolsky, Sabine Wilhelm, Thilo Deckersbach, Alan L Peterson, Matt Specht, John T Walkup, Susanna Chang, John Piacentini
Although tics are the defining feature of chronic tic disorders (CTD), many children experience comorbid internalizing and externalizing problems that contribute to impairment across several domains, including family functioning. The current study examined clinical correlates and predictors of caregiver strain in parents of children with CTD. Participants were 123 children and adolescents diagnosed with a CTD who participated in a randomized-controlled trial of behavior therapy for reducing tics. Results showed that a combination of disruptive behavior, inattention/hyperactivity, and tic intensity best explained objective strain and a combination of inattention/hyperactivity and tic intensity were the best predictors of subjective caregiver strain...
2015: Children's Health Care: Journal of the Association for the Care of Children's Health
https://www.readbyqxmd.com/read/26763495/an-empirical-examination-of-symptom-substitution-associated-with-behavior-therapy-for-tourette-s-disorder
#17
Alan L Peterson, Joseph F McGuire, Sabine Wilhelm, John Piacentini, Douglas W Woods, John T Walkup, John P Hatch, Robert Villarreal, Lawrence Scahill
Over the past six decades, behavior therapy has been a major contributor to the development of evidence-based psychotherapy treatments. However, a long-standing concern with behavior therapy among many nonbehavioral clinicians has been the potential risk for symptom substitution. Few studies have been conducted to evaluate symptom substitution in response to behavioral treatments, largely due to measurement and definitional challenges associated with treated psychiatric symptoms. Given the overt motor and vocal tics associated with Tourette's disorder, it presents an excellent opportunity to empirically evaluate the potential risk for symptom substitution associated with behavior therapy...
January 2016: Behavior Therapy
https://www.readbyqxmd.com/read/26630122/developmental-differences-in-functioning-in-youth-with-social-phobia
#18
Alexandra L Hoff, Philip C Kendall, Audra Langley, Golda Ginsburg, Courtney Keeton, Scott Compton, Joel Sherrill, John Walkup, Boris Birmaher, Anne Marie Albano, Cynthia Suveg, John Piacentini
Social phobia (SoP) in youth may manifest differently across development as parent involvement in their social lives changes and social and academic expectations increase. This cross-sectional study investigated whether self-reported and parent-reported functioning in youth with SoP changes with age in social, academic, and home/family domains. Baseline anxiety impairment data from 488 treatment-seeking anxiety-disordered youth (ages 7-17, N = 400 with a SoP diagnosis) and their parents were gathered using the Child Anxiety Impact Scale and were analyzed using generalized estimating equations...
December 2, 2015: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/26598476/treatment-of-early-age-mania-outcomes-for-partial-and-nonresponders-to-initial-treatment
#19
RANDOMIZED CONTROLLED TRIAL
John T Walkup, Karen Dineen Wagner, Leslie Miller, Gayane Yenokyan, Joan L Luby, Paramjit T Joshi, David A Axelson, Adelaide Robb, Jay A Salpekar, Dwight Wolf, Abanti Sanyal, Boris Birmaher, Benedetto Vitiello, Mark A Riddle
OBJECTIVE: The Treatment of Early Age Mania (TEAM) study evaluated lithium, risperidone, and divalproex sodium (divalproex) in children with bipolar I disorder who were naive to antimanic medication, or were partial or nonresponders to 1 of 3 study medications. This report evaluates the benefit of either an add-on or a switch of antimanic medications for an 8-week trial period in partial responders and nonresponders, respectively. METHOD: TEAM is a randomized, controlled trial of individuals (N = 379) aged 6 to 15 years (mean ± SD = 10...
December 2015: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/26598475/depression-and-suicidality-outcomes-in-the-treatment-of-early-age-mania-study
#20
RANDOMIZED CONTROLLED TRIAL
Jay A Salpekar, Paramjit T Joshi, David A Axelson, Shauna P Reinblatt, Gayane Yenokyan, Abanti Sanyal, John T Walkup, Benedetto Vitiello, Joan L Luby, Karen Dineen Wagner, Nasima Nusrat, Mark A Riddle
OBJECTIVE: To assess the efficacy of mood-stabilizing medications for depression and suicidality in pediatric bipolar disorder. METHOD: The Treatment of Early Age Mania (TEAM) study is a multicenter, prospective, randomized, masked comparison of divalproex sodium (VAL), lithium carbonate (LI), and risperidone (RISP) in an 8-week parallel clinical trial. A total of 279 children and adolescents with DSM-IV diagnoses of bipolar I disorder, mixed or manic, aged 6 to 15 years were enrolled...
December 2015: Journal of the American Academy of Child and Adolescent Psychiatry
keyword
keyword
104005
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"