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https://www.readbyqxmd.com/read/29119592/orthopedic-complications-of-linear-morphea-implications-for-early-interdisciplinary-care
#1
REVIEW
Jennifer J Schoch, Bradley S Schoch, Jean David Werthel, Amy L McIntosh, Dawn M R Davis
Linear morphea of the limb primarily affects children, and extracutaneous manifestations are common. Orthopedic surgeons are often essential in the care of patients with linear morphea, yet there are few reports outlining specific orthopedic complications in this population. We sought to improve the understanding of orthopedic complications in linear morphea of the limb. Between 1999 and 2014, 51 children were evaluated for linear morphea of an extremity. Twenty-six (51%) had documented orthopedic manifestations...
November 9, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29110020/granuloma-annulare-and-morphea-correlation-with-borrelia-burgdorferi-infections-and-chlamydia-related-bacteria
#2
Lauri Tolkki, Kati Hokynar, Seppo Meri, Jaana Panelius, Mirja Puolakkainen, Annamari Ranki
A retrospective study of 109 skin biopsies with granuloma annulare (GA) or morphea histology from patients with suspected tick bite was performed. Biopsies were tested for cutaneous Borrelia burgdorferi DNA using PCR. The same biopsies were analysed for tick-borne novel agents, Chlamydia-related bacteria (members of the Chlamydiales order), using a PCR-based method. Borrelia DNA was detected in 7/73 (9.6%) biopsies with GA and in 1/36 (2.8 %) biopsies with morphea, while Chlamydiales DNA was found in 53/73 (72...
November 7, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29025691/morphea-and-extragenital-lichen-sclerosus-et-atrophicus-after-influenza-vaccination
#3
S Requena López, Y Hidalgo García, S Gómez Díez, B Vivanco Allende
No abstract text is available yet for this article.
October 9, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28993235/the-wood-s-lamp-as-a-tool-in-the-evaluation-of-morphea
#4
Paul Curtiss, Gaurav Singh, Kristen Lo Sicco, Andrew G Franks
No abstract text is available yet for this article.
October 6, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28966531/delayed-treatment-of-generalized-morphea-due-to-misdiagnosis-as-vitiligo-at-an-oriental-medical-clinic
#5
Howard Chu, Jae Won Lee, Young In Lee, Do Young Kim
No abstract text is available yet for this article.
October 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28954874/fibrous-arthropathy-associated-with-morphea-a-new-cause-of-diffuse-acquired-joint-contractures
#6
Etienne Merlin, Sylvain Breton, Sylvie Fraitag, Jean-Louis Stéphan, Carine Wouters, Christine Bodemer, Brigitte Bader-Meunier
Etiologies for childhood-onset diffuse joint contractures encompass a large group of inherited disorders and acquired diseases, in particular a subtype of juvenile idiopathic arthritis called "dry polyarthritis," dermatomyositis, and systemic sclerosis. We report on 2 boys, aged 5 and 8 years, who developed acquired symmetric painless joint contractures preceding the development of superficial plaques of morphea by 7 to 13 months. There was no other clinical involvement, biological inflammation, or autoantibodies...
October 2017: Pediatrics
https://www.readbyqxmd.com/read/28951708/morphea-in-middle-anatolia-turkey-a-5-year-single-center-experience
#7
Isil Bulur, Hilal Kaya Erdoğan, Tekden Karapınar, Zeynep Nurhan Saracoglu
INTRODUCTION: Morphea, also referred to as localized scleroderma, is a rare fibrosing skin disorder of undetermined cause. AIM: We report our single-center experience with morphea. MATERIAL AND METHODS: The study included 53 patients who were diagnosed with morphea by histopathology in our department between 2010 and 2015. Study data were collected retrospectively from the records of morphea patients. RESULTS: The study included 53 patients (38 women, 15 men), and median age at onset was 39...
August 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28898915/-current-therapies-in-superficial-malignant-tumors
#8
Simone Luisa Scholz, Anja Eckstein, Dirk Dekowski, Joachim Esser, Henrike Westekemper, Klaus P Steuhl
This article is a review of diagnostic and therapeutic possibilities in common epibulbar malignant tumors, such as basal cell carcinoma, conjunctival lymphoma, squamous cell carcinoma and conjunctival melanoma. Most importantly, for every tumor patient there is a detailed anamnesis, split lamp examination and photo documentation. Further regular controls after therapy are required due to the risk of recurrences.Basal cell carcinoma is the most common tumor of the periocular skin, divided into three subtypes (nodular, superficial and morphea)...
September 12, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28895373/nodular-morphea-in-a-patient-with-steinert-disease
#9
Elena Campione, Alessandra Ventura, Virginia Garofalo, Claudia Torti, Roberto Massa, Chiara Terracciano, Augusto Orlandi, Luca Bianchi
No abstract text is available yet for this article.
September 8, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28865864/clinicopathologic-and-immunophenotypic-features-of-eosinophilic-fasciitis-and-morphea-profunda-a-comparative-study-of-27-cases
#10
Oluwakemi Onajin, Carilyn N Wieland, Margot S Peters, Christine M Lohse, Julia S Lehman
BACKGROUND: Eosinophilic fasciitis (EF) and morphea profunda (MP) are inflammatory and sclerosing disorders of the subcutis that can exhibit clinical and pathologic presentations that overlap. OBJECTIVE: To identify clinicopathologic features that can be used to distinguish EF from MP. METHODS: We performed a retrospective review of 16 patients with EF and 11 patients with MP. Hematoxylin-eosin, CD123, CD34, and Verhoeff-Van Gieson stains were evaluated on skin biopsies that included the fascia...
August 30, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28839399/linear-morphea-alopecia-new-trichoscopy-findings
#11
Claudia Liliana Montoya, Natalia Calvache
No abstract text is available yet for this article.
April 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28760502/-extensive-connective-tissue-nevus-in-children
#12
O Lafargue, S Fraitag, O Boccara, F Comoz, J Rod, C Turgis Mezerette, A Dompmartin
BACKGROUND: Connective tissue nevus (CTN) is a rare condition of the extracellular matrix components that generally presents as papulae of normal skin colour. This condition may be syndromic or sporadic. PATIENTS AND METHODS: We report herein two isolated cases of extensive and infiltrative CTN in children at risk for subsequent joint stiffening. The pathology samples displayed respectively mixed hamartoma and a collagenoma. DISCUSSION: The onset of these lesions is often difficult to establish, since they are usually unnoticeable at first...
November 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28736199/decreased-hepatitis-b-vaccine-response-in-pediatric-patients-with-atopic-dermatitis-psoriasis-and-morphea
#13
Deepa P Patel, James R Treat, Leslie Castelo-Socio
Multiple groups of patients have been recognized for having high rates of non-responders to the Hepatitis B vaccine including those with HIV, inflammatory bowel disease, and chronic kidney disease. These patients are at increased risk for infection due to both the nature of their underlying diseases and the immunosuppressive drugs they are commonly prescribed. Identification of groups with high non-response rates is essential in order to establish vaccination guidelines and prevent serious infections in already susceptible patients...
August 16, 2017: Vaccine
https://www.readbyqxmd.com/read/28734566/long-term-outcome-of-eosinophilic-fasciitis-a-cross-sectional-evaluation-of-35-patients
#14
Jorre S Mertens, Rogier M Thurlings, Wietske Kievit, Marieke M B Seyger, Timothy R D Radstake, Elke M G J de Jong
BACKGROUND: Eosinophilic fasciitis (EF) is a connective tissue disease with an unknown long-term course. OBJECTIVE: To evaluate presence and determinants of residual disease damage in patients with EF after long-term follow-up. METHODS: Patients with biopsy-proven EF were included for this cross-sectional study. Outcome measures included the Physician's Global Assessment of Disease Activity, Physician's Global Assessment of Damage (PhysGA-D), skin pliability scores, passive range of motion, and health-related quality of Life (HRQoL) questionnaires...
September 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28608042/-granulomatous-reaction-pattern-of-the-skin-interstitial-granulomatous-dermatitis-lymphoma-vasculitis
#15
REVIEW
C Rose, K Holl-Ulrich
A particular diagnostic situation in the classification of a granulomatous dermatitis results when no circumscribed granulomas but instead a diffuse interstitial histiocytic inflammatory infiltrate, a granulomatous vasculitis or a neoplastic lymphocytic infiltrate is found. Interstitial granulomatous dermatitis was originally described in patients with arthritis. Later, it was recognized that there are also associations with other usually immunological diseases. Differentiating between interstitial granulomatous dermatitis and the interstitial form of granuloma annulare, early morphea and variants of borreliosis or scleromyxedema as well as interstitial granulomatous drug reaction can be very difficult...
July 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28604132/the-efficacy-of-methotrexate-in-the-treatment-of-en-coup-de-sabre-linear-morphea-subtype
#16
Ploysyne Rattanakaemakorn, Joseph Jorizzo
BACKGROUND: En coup de sabre is a rare subtype of linear morphea, located on the forehead or frontoparietal scalp. Systemic treatment of localized morphea with methotrexate has been reported in a few clinical reports. However, there are no case series using methotrexate treatment for En coup de sabre. OBJECTIVE: To evaluate the efficacy and tolerability of methotrexate in the treatment of en coup de sabre linear morphea subtype. METHOD: A retrospective chart review was performed for pediatric and the adult patients with en coup de sabre evaluated in the Dermatology Clinic at Wake Forest University School of Medicine treated with methotrexate...
June 12, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28543515/thrombocytopenia-associated-with-localized-scleroderma-report-of-four-pediatric-cases-and-review-of-the-literature
#17
Ankur Kumar Jindal, Anju Gupta, Sunil Dogra, Amit Rawat, Deepti Suri, Jasmina Ahluwalia, Surjit Singh
We report on four children with localized scleroderma (morphea) and thrombocytopenia. All four had the en coup de sabre subtype of morphea and had varying degrees of thrombocytopenia (8 × 10(9) /L to 120 × 10(9) /L). None of them had major bleeding manifestations, and thrombocytopenia resolved with treatment of morphea. (One patient was also given an injection of anti-D immunoglobulin.) We propose that thrombocytopenia associated with localized scleroderma is usually benign and requires no specific therapy...
July 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28543434/metastatic-squamous-cell-carcinoma-in-a-patient-with-disabling-pansclerotic-morphea-of-childhood
#18
Juan M Ruiz-Matta, Luis R Flores-Bozo, Judith Dominguez-Cherit
Disabling pansclerotic morphea of childhood (DPMC) is a rare disorder that confers a risk of developing ulcer-related squamous cell carcinoma (SCC). We describe a young man with long-standing DPMC and SCC with lung metastasis.
May 23, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28537856/superficial-morphea-case-report-look-alikes-pathogenesis-and-treatment
#19
Jameson Loyal, Ivy I Norris, Elizabeth B Lester, Joseph C Pierson
Superficial morphea, a rare variant of morphea, is characterized by hypopigmented to hyperpigmented skin lesions located predominantly in a symmetric fashion at intertriginous sites. These patches and plaques typically lack the significant induration, contractures, and atrophy seen in other subtypes of morphea. Histologic examination is key for accurate diagnosis considering the number of similar conditions which may clinically mimic superficial morphea. Herein, we present a case of a 25-year-old woman who re-presented for consultation in our clinic after gradual progression of her skin lesions...
May 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28507446/methotrexate-an-effective-monotherapy-for-refractory-generalized-morphea
#20
Eftychia Platsidaki, Vassiliki Tzanetakou, Anargyros Kouris, Panagiotis G Stavropoulos
INTRODUCTION: Morphea is an inflammatory skin disorder characterized by excessive collagen deposition. Although treatment algorithms for morphea subtypes have been suggested, no consistent recommendations are available. This study attempts to evaluate the clinical efficacy of methotrexate (MTX) as monotherapy in refractory generalized morphea. METHODS: It is a retrospective study, including 20 patients who had already been treated with various topical and systemic therapies with minimal clinical improvement...
2017: Clinical, Cosmetic and Investigational Dermatology
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