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Lichen sclerosus

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https://www.readbyqxmd.com/read/28219801/ala-photodynamic-treatment-in-lichen-sclerosus-clinical-and-immunological-outcome-focusing-on-the-assesment-of-anti-nuclear-antibodies
#1
Anita Olejek, Iwona Gabriel, Anna Bilska-Janosik, Iwona Kozak-Darmas, Aleksandra Kawczyk-Krupka
BACKGROUND: Lichen sclerosus (LS) is a difficult to treat, often relapsing disease with unknown background. An autoimmune diseases coexist with LS. Over recent years photodynamic therapy (PDT) has been shown to be noninvasive and successful therapeutic approach for the effective treatment many conditions. However, the change of immune status of the patients based on ANA antibodies has not been yet reported. Our aim was to observe the clinical response followed by possible changes in autoimmune antibodies levels before and after PDT...
February 17, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28217480/extragenital-lichen-sclerosus-et-atrophicus-co-exististing-with-pemphigus-vulgaris
#2
Chirag Desai, Utpal Durve, Uday Khopkar
No abstract text is available yet for this article.
January 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28188018/surgical-treatment-of-disabling-conditions-caused-by-anogenital-lichen-sclerosus-in-women-an-account-of-surgical-procedures-and-results-including-patient-satisfaction-benefits-and-improvements-in-health-related-quality-of-life
#3
Filip Rangatchew, Jens Knudsen, Michael V Thomsen, Krzysztof T Drzewiecki
BACKGROUND: Anogenital lichen sclerosus (LS), a chronic dermatitis that causes scarring and introital stenosis, may prevent sexual intercourse and reduce health-related quality of life (QoL). Surgery can restore the anatomy, allowing patients to resume their sexual lives. This study investigates outcomes in women treated with local skin flaps. METHODS: Thirty-eight consecutive LS-verified patients, surgically treated for debilitating conditions between 1990 and 2013, were retrospectively evaluated...
January 9, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28161837/autologous-platelet-rich-plasma-prp-in-chronic-penile-lichen-sclerosus-the-impact-on-tissue-repair-and-patient-quality-of-life
#4
Francesco Casabona, Ilaria Gambelli, Federica Casabona, Pierluigi Santi, Gregorio Santori, Ilaria Baldelli
PURPOSE: Lichen sclerosus (LS) is a chronic inflammatory skin condition that frequently involves the anogenital region. Ongoing research is focused on finding more effective treatments for tissue repair and reducing symptoms. The aim of this study is to evaluate the effectiveness of platelet-rich plasma (PRP) local injections in penile LS. METHODS: Forty-five male patients affected by penile LS underwent injections of autologous PRP in the affected skin areas. Age at diagnosis and at first treatment, number of treatments, clinical conditions (phimosis, splitting, inflammation, synechiae, meatus stenosis), symptoms (pain, burning, itching), and functional impairment were considered...
February 4, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28134725/sclerosing-dermatofibrosarcoma-protuberans-shows-significant-overlap-with-sclerotic-fibroma-in-both-routine-and-immunohistochemical-analysis-a-potential-diagnostic-pitfall
#5
Maram Yousef Odeh Abdaljaleel, Jeffrey P North
Dermatofibrosarcoma protuberans (DFSP) is an uncommon, low-to-intermediate grade sarcoma with several histologic variants, including pigmented (Bednar tumor), sclerosing, myxoid, atrophic, and DFSP with fibrosarcomatous changes. Two patterns of sclerosis in DFSP can be observed, a sclerotic fibroma-like pattern and a morphea/lichen sclerosus-like pattern. Partial biopsies of sclerosing DFSPs with the sclerotic fibroma pattern can be misdiagnosed as sclerotic fibroma or other benign sclerosing tumors (eg, perineurioma, dermatofibroma)...
February 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28124469/lichen-sclerosus-and-risk-of-cancer
#6
Pia M Halonen, Maija I Jakobsson, M A Oskari Heikinheimo, Annika E Riska, Mika V Gissler, Eero I Pukkala
Malignant potential of lichen sclerosus (LS) has been suspected, but evidence is sparse. We used the population-based Finnish Cancer Registry data to further study this connection. We identified all women with the diagnosis of LS (n= 7,616) listed in the Finnish Hospital Discharge Registry from 1970-2012. The cohort was followed through the Finnish Cancer Registry for subsequent cancer diagnoses until 2014. Standardized Incidence Ratios (SIRs) were calculated for different cancers by dividing the observed numbers of cancers by expected ones...
January 25, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28108798/augmented-perineal-urethrostomy-using-a-dorsal-buccal-mucosal-graft-bi-institutional-study
#7
Jessica DeLong, Kurt McCammon, Leandro Capiel, Augustín Rovegno, Jeremy B Tonkin, Gerald Jordan, Ramón Virasoro
PURPOSE: To present our technique and outcomes for perineal urethrostomy augmented with a dorsal onlay buccal mucosa graft (BMG). Results from initial series and collaboration from an international center are included. METHODS: A retrospective chart review of all adult patients who underwent urethral reconstruction with perineal urethrostomy utilizing a buccal mucosal graft between January 1, 2002 and January 1, 2013 was performed. All surgeries were performed by three surgeons using the same technique (GHJ, KAM, and RV)...
January 20, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28087029/lichen-sclerosus-of-the-glans-simulating-melanoma
#8
Pietro Sollena, Giacomo Caldarola, Alessandro Di Stefani, Guido Massi, Ketty Peris
No abstract text is available yet for this article.
February 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28043767/bleeding-after-circumcision-is-more-likely-in-children-with-lichen-sclerosus-balanitis-xerotica-obliterans
#9
P Somov, B K Y Chan, C Wilde, H Corbett
INTRODUCTION: Over 27,000 circumcisions were performed in England in 2012-13. The complication rate is generally perceived to be low, although published figures vary widely. Balanitis xerotica obliterans, more correctly termed Lichen Sclerosus et atrophicus (LS), is one of the commonest indications for medical circumcision. To test the hypothesis that children undergoing circumcision for LS have a higher rate of postoperative bleeding than those undergoing the procedure for other reasons, we retrospectively reviewed records for patients undergoing circumcision...
December 9, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28024127/combined-therapy-in-vulvar-lichen-sclerosus-does-topical-tretinoin-improve-the-efficacy-of-mometasone-furoate
#10
Alessandro Borghi, Sara Minghetti, Giulia Toni, Annarosa Virgili, Monica Corazza
Purpose To assess efficacy and safety profile of combining a potent corticosteroid with a retinoid in in the treatment of vulvar lichen sclerosus (VLS). Methods We retrospectively compared 21 VLS patients treated with tretinoin (T) in short contact therapy and mometasone furoate (MMF) (group A) and 20 treated with cold cream (CC) and MMF (group B) for 5 consecutive days/week for 12 weeks. The efficacy parameters were the response rate, the percentage of patients achieving an improvement from baseline of ≥75% in subjective and objective scores, and the mean reduction in subjective and objective scores...
December 26, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27989640/commentary-to-bleeding-after-circumcision-is-more-likely-in-children-with-lichen-sclerosus-facts-are-stubborn-but-statistics-are-more-pliable
#11
Anne-Françoise Spinoit
No abstract text is available yet for this article.
December 5, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27986140/intradermal-injection-of-autologous-platelet-rich-plasma-for-the-treatment-of-vulvar-lichen-sclerosus
#12
Andrew T Goldstein, Michelle King, Charles Runels, Meghan Gloth, Richard Pfau
No abstract text is available yet for this article.
January 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27978615/lichen-sclerosus-in-stable-sexual-partners-etiologic-correlation-or-mere-coincidence
#13
Marina Ambrifi, Maria G Dona', Marinella Tedesco, Alessandra Latini, Carlo Cota, Massimo Giuliani, Maria Benevolo, Tarik Gheit, Massimo Tommasino, Antonio Cristaudo
No abstract text is available yet for this article.
February 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/27978612/neurofibromatosis-type-1-and-lichen-sclerosus-an-uncommon-association
#14
Emanuele Miraglia, Stefano Calvieri, Sandra Giustini
No abstract text is available yet for this article.
February 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/27975027/use-of-platelet-rich-plasma-for-vulvovaginal-autoimmune-conditions-like-lichen-sclerosus
#15
Fariba Behnia-Willison, Nina Reza Pour, Behrang Mohamadi, Nadia Willison, Madeleine Rock, Ian W Holten, Robert O'Shea, Joseph Miller
BACKGROUND: Lichen sclerosus (LS) is an inflammatory dermatosis with autoimmune pathogenesis. Although relatively common, its true incidence is unknown and likely underestimated. LS is usually anogenital, but in around 10% of patients, it can present as extragenital lesions. Continuous administration of topical corticosteroids is the mainstay of medical treatment. Other treatments are available but are only occasionally prescribed along with or instead of topical steroids. Injection of platelet-rich plasma (PRP) into affected areas has been reported to result in the regeneration of normal skin...
November 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27919664/photodynamic-therapy-with-green-light-for-the-treatment-of-vulvar-lichen-sclerosus-preliminary-results
#16
B J Osiecka, K Jurczyszyn, P Nockowski, M Murawski, P Ziółkowski
INTRODUCTION: The standard treatment for lichen sclerosus (LS) is symptomatic and is primarily based on the chronic use of corticosteroids, sometimes resulting in unsatisfactory effects. Therefore, other non-pharmacological methods are being sought, which are less aggravating for the patient. LS can be treated topically by using photodynamic therapy (PDT) based on 5-aminolevulinic acid (5-ALA). Unfortunately, therapy with the red light is often connected with severe local pain during the illumination...
December 2, 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/27911123/lichen-sclerosus-et-atrophicus-in-a-surgical-scar-treated-with-fractional-laser
#17
Marta Mendieta Eckert, Izaskun Ocerin Guerra, Nerea Landa Gundin
Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory disease of unknown cause that typically affects the genital area(1). It has been reported in post-traumatic areas as a result of Koebner´s phenomenon. LSA responds poorly to treatment making it a therapeutic challenge(2). Laser therapy has been described for LSA with variable results(3,4).
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27908373/management-of-panurethral-stricture
#18
REVIEW
Sanjay Kulkarni, Jyotsna Kulkarni, Sandesh Surana, Pankaj M Joshi
Panurethral stricture, involving the penile and bulbar urethra, is seen across the world .It is a complex disease with a relative paucity of literature on the subject. In India, Lichen Sclerosus is the most common cause of panurethral stricture followed by iatrogenic causes. The article presents the authors' experiences of Panurethral stricture repair using a single stage, One side dissection, dorsal onlay repair with oral mucosa graft.
February 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/27906807/quality-of-life-and-sexual-distress-in-women-with-erosive-vulvovaginal-lichen-planus
#19
Harriet Cheng, Amanda Oakley, John V Conaglen, Helen M Conaglen
OBJECTIVES: Erosive vulvovaginal lichen planus (EVLP) is a chronic and painful genital dermatosis. Little is published about its impact on quality of life. This study aimed to evaluate quality of life and sexual function in women with EVLP. MATERIALS AND METHODS: Women with genital dermatoses were surveyed using the Dermatology Life Quality Index (DLQI) and Hospital Depression and Anxiety Scales. A subgroup completed the Female Sexual Distress Scale and Female Sexual Function Index subscales...
November 30, 2016: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27896230/evaluation-of-symptoms-and-prevention-of-cancer-in-menopause-the-value-of-vulvar-exam
#20
A R Palumbo, C Fasolino, G Santoro, V Gargano, M Rinaldi, B Arduino, M Belli, M Guida
Vulvar and vaginal atrophy (VVA), is a chronic medical condition experienced by postmenopausal women, with prevalence estimated ranging from 10% to 50% [1]. VVA is characterized by a constellation of symptoms, that may affect daily activities, sexuality, relationships, and quality of life [3]. Early recognition and effective treatment of VVA may enhance sexual health and the quality of life of women and their partners. Some vulvar conditions such as lichen sclerosus are more prevalent in the postmenopausal years...
November 2016: Translational Medicine @ UniSa
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